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Ionotropic receptors mediate olfactory learning and memory in Drosophila

Insect Science 2024年第4期31卷 1249-1269页

作者： Md Zeeshan Ali Anushree Aarif Ahsan Mohammad Shamsul ola Rizwanul Haque Jawaid Ahsan Department of Biotechnology Central University of South BiharGayaBiharIndia Department of Radiation Oncology University of MichiganAnn ArborMichiganUSA Department of Biochemistry College of ScienceKing Saud UniversityRiyadhSaudi Arabia

Phenylacetaldehyde(PAH),an aromatic compound,is present in a diverse range of fruits including overripe bananas and prickly pear cactus,the two major host fruits for Drosophila *** acts as a potent ligand for the ionotropic receptor 84a(IR84a)in the adult fruit fly and it is detected by the IR84a/IR8a heterotetrameric *** role in the male courtship behavior through IR84a as an environmental aphrodisiac is of additional *** ***,two distinct kinds of olfactory receptors,that is,odorant receptors(ORs)and ionotropic receptors(IRs),perceive the odorant *** display unique structural,molecular,and functional characteristics in addition to having different evolutionary ***,olfactory cues detected by the ORs such as ethyl acetate,1-butanol,isoamyl acetate,1-octanol,4-methylcyclohexanol,*** as aliphatic esters and alcohols have been employed in olfactory classical conditioning using fruit *** underlines the participation of OR-activated olfactory pathways in learning and memory *** study elucidates that likewise ethyl acetate(EA)(an OR-responsive odorant),PAH(an IR-responsive aromatic compound)too can form learning and memory when associated with an appetitive gustatory *** association of PAH with sucrose(PAH/SUC)led to learning and formation of the long-term memory(LTM).Additionally,the Orco^(1),Ir84a^(MI00501),and Ir8a^(1)mutant flies were used to confirm the exclusive participation of the IR84a/IR8a complex in PAH/SUC olfactory associative *** results highlight the involvement of IRs via an IR-activated pathway in facilitating robust olfactory behavior.

关键词： appetitive conditioning Drosophila melanogaster ethyl acetate ionotropic receptors learning and memory phenylacetaldehyde

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Conflicts & Immigration Impacts on Built Environment: A Case Study of Arab Marshes in Iraq

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Journal of Geoscience and Environment Protection 2024年第9期12卷 33-50页

作者： ola Saad Znad University College of Dublin Dublin Ireland

The importance of water to our lives cannot be overemphasized as it is the source of all living things. Water scarcity is a concern in many Middle Eastern nations due to war and politics. Many people lose their essence due to actions made by their rulers, such as the Marsh Arabs. Water and biodiversity should be considered, and governments should be held accountable for attaining a more balanced lifestyle and reducing immigrant levels. Many academics have also explored the hydro-immigration of marshland residents. They suffer more hazards due to a lack of money, poor education, and social instability than their colleagues who remain in their own country. Furthermore, they have insufficient health care and have difficulty integrating into the new community. This implies that not all nations that receive such migrants can implement programs to assist the immigrants. This research reveals how wars, hydro-politics, and immigration issues have drastically affected architecture and social structures in the Arab Marshes region, leading to ecological destruction, mass migrations, and cultural loss. Therefore, this work focuses on the need to critically investigate all factors covered within the context of this research.

关键词： Immigration Hydro Politics Social and Culture Ecology

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Cardiac differentiation is modulated by anti-apoptotic signals in murine embryonic stem cells

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World Journal of Stem Cells 2024年第5期16卷 551-559页

作者： Amani Yehya Joseph Azar Mohamad Al-Fares Helene Boeuf Wassim Abou-Kheir Dana Zeineddine ola Hadadeh Department of Anatomy Cell Biology and Physiological SciencesAmerican University of BeirutBeirut 1107-2020Lebanon Inserm BiotisU1026University BordeauxBordeaux F-33000France Rammal Rammal Lab Physio-Toxicity Environmental TeamFaculty of SciencesLebanese UniversityNabatieh 0000Lebanon

BACKGROUND Embryonic stem cells(ESCs)serve as a crucial ex vivo model,representing epiblast cells derived from the inner cell mass of blastocyst-stage *** exhibit a unique combination of self-renewal potency,unlimited proliferation,and *** latter is evident by the ability of the isolated cells to differ-entiate spontaneously into multiple cell lineages,representing the three primary embryonic germ *** regulatory networks guide ESCs,directing their self-renewal and lineage-specific ***,or programmed cell death,emerges as a key event involved in sculpting and forming various organs and structures ensuring proper embryonic ***-ever,the molecular mechanisms underlying the dynamic interplay between diffe-rentiation and apoptosis remain poorly *** To investigate the regulatory impact of apoptosis on the early differentiation of ESCs into cardiac cells,using mouse ESC(mESC)models-mESC-B-cell lym-phoma 2(BCL-2),mESC-PIM-2,and mESC-metallothionein-1(MET-1)-which overexpress the anti-apoptotic genes Bcl-2,Pim-2,and Met-1,*** mESC-T2(wild-type),mESC-BCL-2,mESC-PIM-2,and mESC-MET-1 have been used to assess the effect of potentiated apoptotic signals on cardiac *** hanging drop method was adopted to generate embryoid bodies(EBs)and induce terminal differentiation of *** size of the generated EBs was measured in each condition compared to the wild *** the functional level,the percentage of cardiac differentiation was measured by calculating the number of beating cardiomyocytes in the manipulated mESCs compared to the *** the molecular level,quantitative reverse transcription-polymerase chain reaction was used to assess the mRNA expression of three cardiac markers:Troponin T,GATA4,and ***,troponin T protein expression was evaluated through immunofluorescence and western blot *** Our findings showed that the upregulation of Bcl-

关键词： Mouse embryonic stem cells Self-renewal Apoptosis Cardiac differentiation B-cell lymphoma 2 PIM-2 Metallothionein-1

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Assessing the impact of booster vaccination on diphtheria transmission:Mathematical modeling and risk zone mapping

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Infectious Disease Modelling 2024年第1期9卷 245-262页

作者： Ilham Saiful Fauzi Nuning Nuraini ade Maya Sari Imaniah Bazlina Wardani Delsi Taurustiati Purnama Magdalena Simanullang Bony Wiem Lestari Department of Accounting Politeknik Negeri MalangMalangIndonesia Department of Mathematics Faculty of Mathematics and Natural SciencesInstitut Teknologi BandungBandungIndonesia Center for Mathematical Modeling and Simulation Institut Teknologi BandungBandungIndonesia Study Program of Biology Education Faculty of Education and Teacher TrainingUIN Kiai Haji Achmad Siddiq JemberJemberIndonesia West Java Provincial Health Office West JavaIndonesia Department of Public Health Faculty of MedicineUniversitas PadjadjaranBandungIndonesia Department of Internal Medicine Radboud Institute for Health SciencesRadboud University Medical CentreNijmegenthe Netherlands

The COVID-19 pandemic caused significant disruptions in the healthcare system,affecting vaccinations and the management of diphtheria *** a consequence of these disruptions,numerous countries have experienced a resurgence or an increase in diphtheria *** Java province in Indonesia is identified as one of the high-risk areas for diphtheria,experiencing an upward trend in cases from 2021 to *** analyze the situation,we developed an SIR model,which integrated DPT and booster vaccinations to determine the basic reproduction number,an essential parameter for infectious *** spatial analysis of geo-referenced data,we identified hotspots and explained diffusion in diphtheria case *** calculation of R0 resulted in an R0=1.17,indicating the potential for a diphtheria outbreak in West *** control the increasing cases,one possible approach is to raise the booster vaccination coverage from the current 64.84%to 75.15%,as suggested by simulation ***,the spatial analysis revealed that hot spot clusters were present in the western,central,and southern regions,posing a high risk not only in densely populated areas but also in rural *** diffusion pattern of diphtheria clusters displayed an expansion-contagious *** the rising trend of diphtheria cases and their geographic distribution can offer crucial insights for government and health authorities to manage the number of diphtheria cases and make informed decisions regarding the best prevention and intervention strategies.

关键词： Diphtheria Vaccination Mathematical modeling SIR model Hot spot analysis

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东方祥瑞话“龙”年

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环球飞行 2024年第2期 58-63页

作者： ade 不详

共赏新月之辉,同庆新岁之始。2024年是农历甲辰龙年,自年初起,大街小巷便洋溢着龙年的氛围寄寓着人们对新一年的美好期盼。龙,这一传说中的神圣生物,承载着人们对于风调雨顺的祈愿。作为十二生肖中唯一一种现实中不存在的动物,龙却是最... 详细信息

共赏新月之辉,同庆新岁之始。2024年是农历甲辰龙年,自年初起,大街小巷便洋溢着龙年的氛围寄寓着人们对新一年的美好期盼。龙,这一传说中的神圣生物,承载着人们对于风调雨顺的祈愿。作为十二生肖中唯一一种现实中不存在的动物,龙却是最受崇拜的神兽之一,被视为古代中国皇权的象征。《尔雅·翼·释龙》记载了龙的外形特征:“角似鹿、头似驼、眼似兔、颈似屋、麟似鱼、爪似鹰、掌似虎、耳似牛。”古代人认为龙是由八种动物的特点结合形成的物种,所以龙又被称为“鳞虫之长”。

关键词：外形特征十二生肖鳞虫

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Characteristics of Biopellets Manufactured from Various Lignocellulosic Feedstocks as Alternative Renewable Energy Sources

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Journal of Renewable Materials 2024年第6期12卷 1103-1123页

作者： Anggara Ridho Putra Apri Heri Iswanto Arif Nuryawan Saptadi Darmawan ElvaraWindra Madyaratri Widya Fatriasari Lee Seng Hua Petar Antov Harisyah Manurung ade Pera Amydha Sudrajat Herawati Pendi Department of Forest Products Faculty of ForestryUniversitas Sumatera Utara.Kampus USU Padang BulanMedan20155Indonesia Research Center for Biomass and Bioproducts National Research and Innovation Agency(BRIN)Jl Raya Bogor KM 46 CibinongBogor16911Indonesia Department of Wood Industry Faculty of Applied SciencesUniversiti Teknologi MARA(UiTM)Cawangan Pahang Kampus JengkaShah Alam26400Malaysia Faculty of Forest Industry University of ForestrySofia1797Bulgaria

The increased valorization of renewable and cost-effective lignocellulosic feedstocks represents a viable,sustainable,and eco-friendly approach toward the production of biopellets as alternative energy *** aim of this research work was to investigate and evaluate the feasibility of using various lignocellulosic raw materials,i.e.,raru(Cotylelobium melanoxylon),mangrove(Rhizophora spp.),sengon(Paraserianthes falcataria),kemenyan toba(Styrax sumatrana),oil palm(Elaeis guineensis),manau rattan(Calamus manan),and belangke bamboo(Gigantochloa pruriens)for manufacturing biopellets with different particle *** raw materials used were tested for their moisture content,specific gravity,ash,cellulose,and lignin *** addition,thermal analyses,i.e.,calorific values,thermogravimetric analysis(TGA),and differential scanning calorimetry(DSC),were *** following properties of the biopellets produced were investigated:moisture content,volatile matter,ash content,fixed carbon,density,and thermal *** on an analysis of the raw materials,raru had the lowest moisture content(12%)and ash content(1.5%)and the highest specific gravity(1.2).Markedly,palm oil stem had the highestα-cellulose(55%)and lignin(37%)*** accordance with the SNI 8675:2018 standard requirements,biopellets with optimal properties(moisture content of 1.4%,ash content of 0.79%,density of 1.09 g/m^(3),calorific value of 4672 cal/g,and TGA residue of 13.9%),were manufactured from raru wood.

关键词： Biomass biopellet renewable energy particle size

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Progression of Corneal Astigmatism after Phaco-Alternative at the University Hospital Center of the Oueme-Plateau Department in Porto-Novo

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Open Journal of Ophthalmology 2024年第3期14卷 313-323页

作者： Chakiratou olaïdé Adoukê Abouki Edjrokinto Ahomadegbe Djrodéhou Espérancia Neuilly Issifou Amadou Alfa Bio Nestor Aïgbè Soulé Alamou Lisette Odoulami Ignace Sounouvou Regional Teaching Hospital of Oueme/Plateau Porto-Novo Benin Regional Teaching Hospital of Borgou and Alibori Parakou Benin Hubert Koutoukou MAGA National Hospital Center of Cotonou Cotonou Benin District Teaching Hospital of Suru-Lere Cotonou Benin

Objective: To study the postoperative evolution of corneal astigmatism following phaco-alternative at the University Hospital Center of Ouémé-Plateau (UHC-OP) in Porto-Novo. Method: This was a prospective, cross-sectional study with a descriptive and analytical purpose conducted from April 19 to September 20, 2021;a period of 6 months. The study included all patients presenting with senile or non-senile cataracts without a history of corneal trauma and who underwent phaco-alternative during the study period. Results: A total of 62 eyes underwent phaco-alternative. The average age was 63 ± 12 years with a male predominance of 59.7%. Phaco-alternative was performed with 74.2% linear incision and 25.8% smile incision. Perioperative incidents were mainly capsular ruptures with vitreous loss occurring in 8.1% of cases. The mean preoperative astigmatism was 1.29 ± 1.5 D with an axis of 180˚ ± 20˚, indicating with-the-rule astigmatism. The mean postoperative astigmatism was 2.2 ± 1.5 D with an axis of 90˚ ± 20˚, indicating against-the-rule astigmatism. The mean induced astigmatism at Day 30 was 1.4 ± 1.2 D for smile incision and 1.8 ± 1.2 D for linear incision. Conclusion: Phaco-alternative yields good results with few complications but remains astigmatogenic. The smile incision appears to be less astigmatogenic.

关键词： Cataract Phaco-Alternative Smile Incision Astigmatism

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Digital earth applications in the twenty-first century

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International Journal of Digital Earth 2014年第7期7卷 511-515页

作者： Rolf ade By Yola Georgiadou Faculty of Geo-Information Science and Earth Observation(ITC) University of TwenteEnschedeThe Netherlands

In these early years of the twenty-first century,we must look at how the truly cross-cutting information technology supports other innovations,and how it will funda-mentally change the information positions of government,private sector and the scientific domain as well as the *** those positions,location will be a prominent linking *** classical top-down system architectures of information exchange will be diluted by peer-to-peer and bottom-up channels,forcing us to rethink their *** should not only focus on better architectures,but need to attend to a different economy of information exchange,in which the‘client’is not only the information sink,but has become an important source as *** laws of this rising‘infoconomy’have yet to be settled *** special issue on‘Digital Earth Applications:Technological design and organizational strategies’brings together a number of papers that shed light on this future information ecosystem in which location-specific information will be exchanged between *** introduction presents a framework that combines geoinformation streams and organisations brokering between government,science,private sector and *** novel framework helps us improve the appreciation of those papers.

关键词： geoinformation governance information architecture digital earth

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Approximate analytical solution of the Dirac equation with q-deformed hyperbolic Poschl–Teller potential and trigonometric Scarf II non-central potential

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Chinese Physics B 2015年第3期24卷 48-54页

作者： ade Kurniawan A.Suparmi C.Cari Physics Department Sebelas Maret University

An approximate solution of the Dirac equation for a spin-1/2 particle under the influence of q-deformed hyperbolic P ¨oschl–Teller potential combined with trigonometric Scarf II non-central potential is studied analytically. It is assumed that the scalar potential equals the vector potential in order to obtain analytical solutions. Both radial and angular parts of the Dirac equation are solved using the Nikiforov–Uvarov method. A relativistic energy spectrum and the relation between quantum numbers can be obtained using this method. Several quantum wave functions corresponding to several states are also presented in terms of the Jacobi Polynomials.

关键词： Dirac equation q-deformed hyperbolic function Poschl–Teller potential trigonometric Scarf II potential

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Effects of reduction on the catalytic performance of limonite ore

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Journal of Energy Chemistry 2018年第5期27卷 1489-1495页

作者： Keisuke Abe ade Kurniawan Takahiro Nomura Tomohiro Akiyama Graduate school of Engineering Hokkaido University Sapporo 060-8628 Japan Center for Advanced Research of Energy and Materials Hokkaido University Sapporo 060-8628 Japan

The catalytic performance of Ni-containing limonite ore in the dry reforming reaction of methane （CH_4＋CO_2→2H_2＋2CO） was determined before and after hydrogen reduction, and under a flow of hydrogen. After hydrogen reduction, the limonite ore exhibited higher catalytic performance, because of the formation of Fe-Ni. However, the Fe in Fe-Ni was readily oxidized by the input CO_2 gas. resulting in a rapid decrease in the catalytic performance of limonite ore. The performance de- crease was due to a decrease in the Ni surface area; Ni could not dissolve in iron oxides and this caused segregation in the iron oxides. When the reaction was conducted under a hydrogen flow, the Fe-Ni was formed and maintained. Ni was highly dispersed in the Fe-Ni phase, resulting in greater surface area of Ni and higher conversion rate of CH_4 and CO_2. The catalytic performance of the limonite ore was inferior to the Ni/Al_2O_3 catalyst because the effect of catalyst support was small, however, the limonite ore was more stable during catalytic use and much cheaper than the Ni/Al_2O_3.

关键词： Limonite Dry reforming Fe-Ni Catalyst

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