检索结果-南通市图书馆

MRBLES 2.0: High-throughput generation of chemically functionalized spectrally and magnetically encoded hydrogel beads using a simple single-layer microfluidic device

引用

Microsystems & Nanoengineering 2020年第1期6卷 145-157页

作者： Yinnian Feng adam k.white Jamin B.Hein Eric A.Appel Polly M.Fordyce Department of Genetics Stanford UniversityStanfordCA 94305USA Department of Bioengineering Stanford UniversityStanfordCA 94305USA Department of Biology Stanford UniversityStanfordCA 94305USA The Novo Nordisk Foundation Center for Protein Research Faculty of Health and Medical SciencesUniversity of CopenhagenBlegdamsvej 3b2200 CopenhagenDenmark Department of Materials Science&Engineering Stanford UniversityStanfordCA 94305USA Stanford ChEM-H Stanford UniversityStanfordCA 94305USA Chan Zuckerberg Biohub San FranciscoCA 94110USA

The widespread adoption of bead-based multiplexed bioassays requires the ability to easily synthesize encoded microspheres and conjugate analytes of interest to their ***,we present a simple method(MRBLEs 2.0)for the efficient high-throughput generation of microspheres with ratiometric barcode lanthanide encoding(MRBLEs)that bear functional groups for downstream surface *** production in MRBLEs 2.0 relies on the manual mixing of lanthanide/polymer mixtures(each of which comprises a unique spectral code)followed by droplet generation using single-layer,parallel flow-focusing devices and the off-chip batch polymerization of droplets into *** streamline downstream analyte coupling,MRBLEs 2.0 crosslinks copolymers bearing functional groups on the bead surface during bead *** the MRBLEs 2.0 pipeline,we generate monodisperse MRBLEs containing 48 distinct well-resolved spectral codes with high throughput(>150,000/min and can be boosted to 450,000/min).We further demonstrate the efficient conjugation of oligonucleotides and entire proteins to carboxyl MRBLEs and of biotin to amino ***,we show that MRBLEs can also be magnetized via the simultaneous incorporation of magnetic nanoparticles with only a minor decrease in the potential code *** the advantages of dramatically simplified device fabrication,elimination of the need for custom-made equipment,and the ability to produce spectrally and magnetically encoded beads with direct surface functionalization with high throughput,MRBLEs 2.0 can be directly applied by many labs towards a wide variety of downstream assays,from basic biology to diagnostics and other translational research.

关键词： beads spectral functional

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Spatio-temporal coupled mode theory for nonlocal metasurfaces

引用

Light(Science & Applications) 2024年第2期13卷 267-282页

作者： adam Overvig Sander A.Mann Andrea Alù Photonics Initiative Advanced Science Research CenterCity University of New YorkNew YorkNY10031USA Physics Program Graduate Center of the City University of New YorkNew YorkNY10016USA

Diffractive nonlocal metasurfaces have recently opened a broad range of exciting developments in nanophotonics research and applications,leveraging spatially extended—yet locally patterned—resonant modes to control light with new degrees of *** conventional grating responses are elegantly captured by temporal coupled mode theory,current approaches are not well equipped to capture the arbitrary spatial response observed in the nascent field of nonlocal ***,we introduce spatio-temporal coupled mode theory(STCMT),capable of elegantly capturing the key features of the resonant response of wavefront-shaping nonlocal *** framework can quantitatively guide nonlocal metasurface design while maintaining compatibility with local metasurface frameworks,making it a powerful tool to rationally design and optimize a broad class of ultrathin optical *** validate this STCMT framework against full-wave simulations of various nonlocal metasurfaces,demonstrating that this tool offers a powerful semi-analytical framework to understand and model the physics and functionality of these devices,without the need for computationally intense full-wave *** also discuss how this model may shed physical insights into nonlocal phenomena in photonics and the functionality of the resulting *** a relevant example,we showcase STCMT’s flexibility by applying it to study and rapidly prototype nonlocal metasurfaces that spatially shape thermal emission.

关键词： theory resonant spatially

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applying Earth Observation Technologies to Economic Consequence Modeling:A Case Study of COVID‑19 in Los Angeles County,California

引用

International Journal of Disaster Risk Science 2024年第1期15卷 18-31页

作者： Fynnwin Prager Marina T.Mendoza Charles k.Huyck adam Rose Paul Amyx Gregory Yetman kristy F.Tiampo California State University Dominguez HillsCarsonCA 90747USA ImageCat Inc.Long BeachCA 90802USA University of Southern California Los AngelesCA 90015USA CIESIN–Center for International Earth Science Information Network Columbia UniversityPalisadesNY 10964USA Cooperative Institute for Research in Environmental Sciences(CIRES) University of Colorado BoulderBoulderCO 80309USA

Earth observation(EO) technologies,such as very high-resolution optical satellite data available from Maxar,can enhance economic consequence modeling of disasters by capturing the fine-grained and real-time behavioral responses of businesses and the *** investigated this unique approach to economic consequence modeling to determine whether crowd-sourced interpretations of EO data can be used to illuminate key economic behavioral responses that could be used for computable general equilibrium modeling of supply chain repercussions and resilience *** applied our methodology to the COVID-19 pandemic experience in Los Angeles County,California as a case *** also proposed a dynamic adjustment approach to account for the changing character of EO through longer-term disasters in the economic modeling *** found that despite limitations,EO data can increase sectoral and temporal resolution,which leads to significant differences from other data sources in terms of direct and total impact *** findings from this analytical approach have important implications for economic consequence modeling of disasters,as well as providing useful information to policymakers and emergency managers,whose goal is to reduce disaster costs and to improve economic resilience.

关键词： Computable general equilibrium models COVID-19 Disaster economic impacts Earth observation Economic consequence analysis Los Angeles County

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pro and anti-inflammatory diets as strong epigenetic factors in inflammatory bowel disease

引用

World Journal of Gastroenterology 2024年第27期30卷 3284-3289页

作者： Adele Rostami kristen white kamran Rostami Digestive Health Clinic Palmerston North 4410New Zealand Digestive Health Clinic&kōtare Wellness Ltd Palmerston North 4410New Zealand Department of Gastroenterology Palmerston North HospitalPalmerston North 4442New Zealand

Inflammatory bowel disease(IBD)is the consequence of a complex interplay between environmental factors,like dietary habits,that alter intestinal microbiota in response to luminal antigens in genetically susceptible *** represents an auspicious area for the discovery of how environmental factors influence the pathogenesis of inflammation,prognosis,and response to ***,it relates to gene expression control in response to environmental *** increasing number of patients with IBD globally is indicative of the negative effects of a food supply rich in trans and saturated fats,refined su-gars,starches and additives,as well as other environmental factors like seden-tarism and excess bodyweight,influencing the promotion of gene expression and increasing DNA hypomethylation in *** many genetic variants are now associated with Crohn's disease(CD),new therapeutic strategies targeting modi-fiable environmental triggers,such as the implementation of an anti-inflammatory diet that involves the removal of potential food antigens,are of growing interest in the current ***,as a strong epigenetic factor in the pathogenesis of inflammatory disorders like IBD,provides novel insights into the pathophysio-logy of intestinal and extraintestinal inflammatory disorders.

关键词： Inflammatory bowel disease Epigenetic Anti-inflammatory diet Immunogenetics Microbiome Polymeric diet Elemental diet

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Non-symmetric differentially subordinate martingales and sharp weak-type bounds for Fourier multipliers

引用

Science China Mathematics 2024年第8期67卷 1807-1826页

作者： Meryem Akboudj Yong Jiao adam Osękowski School of Mathematics and Statistics Hunan Key Laboratory of Analytical Mathematics and ApplicationsCentral South UniversityChangsha 410075China Faculty of Mathematics Informatics and MechanicsUniversity of WarsawWarsaw 02-097Poland

Let p>2 be a given *** this paper,we prove,with the best constant,the weak-type(p,p)inequality■for a large class of non-symmetric Fourier multipliers T_(m) obtained via modulation of jumps of certain Lévy *** particular,the estimate holds for appropriate linear combinations of second-order Riesz transforms and skew versions of the Beurling-Ahlfors operator on the complex *** proof rests on a novel probabilistic bound for Hilbert-space-valued martingales satisfying a certain non-symmetric subordination *** applications to harmonic functions and Riesz systems on Euclidean domains are indicated.

关键词： weak-type bound Fourier multiplier martingale differential subordination laminate

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effective thermal conductivity estimation using a convolutional neural network and its application in topology optimization

引用

Energy and AI 2024年第1期15卷 236-247页

作者： Andre adam Huazhen Fang Xianglin Li Department of Mechanical Engineering University of Kansas1530 W 15th St.Lawrence66045KSUSA Department of Mechanical Engineering and Materials Science Washington University in St.LouisOne Brookings DriveSt.Louis63130MOUSA

Topology optimization of heterogeneous structures can find significant use in a wide range of applications,and its fabrication has been made possible by recent advances in additive ***,the optimization procedure is computationally expensive,as each structural update requires the re-evaluation of the *** computational time is the major limiting factor in large-scale and complex structural *** this study,a convolutional neural network(CNN)model for predicting effective thermal conductivity inspired by the VGG networks is *** using 130,000 unique binary images,the model achieves high predictive ***,it shows a mean absolute percent error(MAPE)of 0.35%in testing when the thermal conductivity of the solid is ten times larger than the fluid,and when the thermal conductivities assigned are that of aluminum and water,the MAPE is 2.35%.The prediction time is 15 ms for a single image with 128×128 pixels,which is 3 to 5 orders of magnitude faster than a finite volume *** employed in topology optimization,the CNN retains a MAPE between 0.67%and 11.8%for different *** CNN model correctly predicts trends in effective thermal conductivity and improves the structure to close proximity of a theoretical maximum in all cases.

关键词： Machine learning Effective thermal conductivity Convolutional neural network VGG Numerical heat transfer Topology optimization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The rate of deadwood decomposition processes in tree stand gaps resulting from bark beetle infestation spots in mountain forests

引用

Forest Ecosystems 2024年第3期11卷 339-346页

作者： Ewa Błonska adam Gorski Jarosław Lasota Department of Ecology and Silviculture Faculty of ForestryUniversity of Agriculture in Krakow29 Listopada 46 Str.31-425KrakowPoland

Decaying wood is an essential element of forest ecosystems and it affects its other *** aim of our research was to determine the decomposition rate of deadwood in various humidity and thermal conditions in the gaps formed in the montane forest *** research was carried out in the Babiog orski National *** research plots were marked out in the gaps of the stands,which were formed as a result of bark beetle *** plots were located in undisturbed *** research covered wood of two species–spruce and beech in the form of cubes with dimensions of 50 mm×50 mm×22 *** samples were placed directly on the soil surface and subjected to laboratory analysis after 36 months.A significant influence of the wood species and the study plot type on the physicochemical properties of the tested wood samples was *** characteristics strongly correlated with soil moisture.A significantly higher mass decline of wood samples was recorded on the reference study plots,which were characterized by more stable moisture *** decomposition of wood in the gaps regardless of the species is related to lower *** wood species covered by the study differed in the decomposition *** wood samples were characterized by a significantly higher decomposition rate compared to beech wood *** research has confirmed that disturbances that lead to the formation of gaps have a direct impact on the decomposition process of deadwood.

关键词： Bark beetle Beech Decomposition rate Forest ecosystem Mass decline Spruce Woody debris

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pioneering the direct large-scale laser printing of flexible“graphenic silicon”self-standing thin films as ultrahigh-performance lithium-ion battery anodes

引用

Carbon Energy 2024年第7期6卷 26-40页

作者： Avinash kothuru adam Cohen Gil Daffan Yonatan Juhl Fernando Patolsky School of Chemistry Faculty of Exact SciencesTel Aviv UniversityTel AvivIsrael Department of Materials Science and Engineering The Iby and Aladar Fleischman Faculty of EngineeringTel Aviv UniversityTel AvivIsrael

Recent technological advancements,such as portable electronics and electric vehicles,have created a pressing need for more efficient energy storage ***-ion batteries(LIBs)have been the preferred choice for these applications,with graphite being the standard anode material due to its ***,graphite falls short of meeting the growing demand for higher energy density,possessing a theoretical capacity that lags *** address this,researchers are actively seeking alternative materials to replace graphite in commercial *** promising avenue involves lithiumalloying materials like silicon and phosphorus,which offer high theoretical ***-silicon composites have emerged as a viable option,showing improved capacity and performance over traditional graphite or pure silicon ***,the existing methods for synthesizing these composites remain complex,energy-intensive,and costly,preventing widespread adoption.A groundbreaking approach is presented here:the use of a laser writing strategy to rapidly transform common organic carbon precursors and silicon blends into efficient“graphenic silicon”composite thin *** films exhibit exceptional structural and energy storage *** resulting three-dimensional porous composite anodes showcase impressive attributes,including ultrahigh silicon content,remarkable cyclic stability(over 4500 cycles with∼40%retention),rapid charging rates(up to 10 A g^(-1)),substantial areal capacity(>5.1 mAh cm^(-2)),and excellent gravimetric capacity(>2400 mAh g^(-1) at 0.2 A g^(-1)).This strategy marks a significant step toward the scalable production of high-performance LIB *** widely available,cost-effective precursors,the laser-printed“graphenic silicon”composites demonstrate unparalleled performance,potentially streamlining anode production while maintaining exceptional *** innovation not only paves the way for advanced LIBs but also sets a precedent for

关键词： 4D printing energy storage fast-charging laser-induced graphene lithium-ion silicon carbon composite anodes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Community-led total sanitation(CLTS)implementation in West Mamprusi Municipal Assembly in *** do communities think eleven years on?

引用

Global Health Journal 2024年第2期8卷 67-73页

作者： Elijah adam Emmanuel Badu School of Media Creative and Social InquiryCurtin UniversityBentleyWestern AustraliaAustralia School of Population Health Curtin UniversityBentleyWestern AustraliaAustralia

Objective Access to improved sanitation is a fundamental human right and an important aspect of Public ***,an estimated thousands of people in Ghana especially,the West Mamprusi Municipal Assembly(WMMA)still have no access to adequate toilet *** has brought untold health repercussions to the inhabitants,the community,and the environment at *** address this menace,the community-led total sanitation(CLTS)was *** study aimed to assess communities’perspectives on the implementation of CLTS and to understand the factors influencing its success and *** A mixed-method approach involving sequential qualitative and quantitative methods was employed in this *** for the quantitative study were randomly selected and surveyed using *** qualitative study employed focus group discussion involving purposively sampled participants including assembly members,opinion leaders,and assembly *** The CLTS program in WMMA realized an apparent use of construction and proper use of household latrines leading to a reduction of open defecation free(ODF)and two communities achieving sanitized status in the history of the study area,enabling the training of latrine artisans and natural leaders to facilitate the CLTS expansion and sustainability,improved sanitation and hygiene,strengthened the enforcement of community rules and regulations and many *** The CLTS program has received more widespread acceptance in the study area than the previous government policy of constructing public toilets,which was greeted with massive failures due to poor *** ensure that gains achieved through CLTS implementation are sustained longer,it is recommended that chiefs and opinion leaders should be involved in the CLTS programs to ensure checks and *** entrenchment of bylaws and more education to address enduring myths and misconceptions will sustain the *** in the form

关键词： Community-led total sanitation(CLTS) Community development Ghana Sanitation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

‘Jelly to Joule’:Direct laser writing of sustainable jellyfish-based ‘graphenic silicon’ anodes for environmentally remediating high-performance lithium-ion batteries

引用

Journal of Energy Chemistry 2024年第10期97卷 553-565,I0012页

作者： Gil Daffan adam Cohen Yuval Sharaby Roman Nudelman Shachar Richter Fernando Patolsky Department of Materials Science and Engineering the Iby and Aladar Fleischman Faculty of EngineeringTel Aviv UniversityTel Aviv 69978Israel school of Chemistry Faculty of Exact SciencesTel Aviv UniversityTel Aviv 69978Israel

The ramifications of global climate change and resource scarcities have made it imperative to re-examine the definition of sustainable energy-storage *** is crucial to recognize that not all renewable resources are inherently sustainable,and their full impact on the environment must be *** the proliferation of invasive jellyfish species wreaking havoc on marine ecosystems and economies worldwide,utilizing overabundant jellyfish as a carbon source presents an opportunity to create energy-storage systems that are both financially beneficial and environmentally ***,a comprehensive approach to sustainability also requires eco-friendly solutions throughout the entire lifecycle,from material sourcing to battery production,without compromising highperformance ***,most electrode syntheses for lithium-ion batteries(LIBs) employed are energy-intensive,multiple-steps,complex,and *** response,this work pioneers the straightforward use of low-energy laser irradiation of a jellyfish biomass/silicon nanoparticle blend to encapsulate the silicon nanoparticles in-situ within the as-forming conductive carbonized matrix,creating sustainable and additive-free composite *** self-standing anode is directly synthesized under ambient conditions and requires no ***,a laser-synthesized conductive threedimensional porous carbon/silicon composite anode from raw jellyfish biomass for LIBs is presented,displaying outstanding cyclic stability(>1000 cycles),excellent capacity retention(>50% retention after1000 cycles),exceptional coulombic efficiency(>99%),superb reversible gravimetric capacity(>2000 mAh/g),and high rate performance capability(>1.6 A/g),paving a new path to future sustainable energy production.

关键词： Laser Silicon Carbon Jellyfish Sustainable Lithium Biomass

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：