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Evolution of heart transplant donor characteristics in the 21st century: A United states single center’s experience

World Journal of Transplantation 2024年第3期14卷 22-29页

作者： Alexander M spring Christiana Gjelaj shivank Madan snehal R Patel Omar saeed sandhya Murthy Yogita Rochlani Daniel B sims sasha Vukelic stephen J Forest Jamil F Borgi Daniel J Goldstein Ulrich P jorde Montefiore-Einstein Center for Heart and Vascular Care Montefiore Medical CenterAlbert Einstein College of MedicineBronxNY 10467United States Division of Cardiothoracic surgery Tulane UniversityNew OrleansLA 70112United States

Despite a record setting number of heart transplants performed annually,the national donor shortage continues to plague transplant teams across the United *** we describe the barriers to adaptation of numerous“non-traditional”orthotopic heart transplant donor characteristics including donors with hepatitis C virus,those meeting criteria for donation after cardiac death,donors with coronavirus disease 19 infection,donors with the human immunodeficiency virus,and grafts with left ventricular systolic *** center’s objective was to increase our transplant volume by expanding our donor pool from“traditional”donors to these“non-traditional”*** detail how medical advances such as certain laboratory studies,pharmacologic interventions,and organ care systems have allowed our center to expand the donor pool thereby increasing transplantation volume without adverse effects on outcomes.

关键词： Orthotopic heart transplantation Hepatitis C virus COVID-19 Left ventricular systolic dysfunction Human immunodeficiency virus Donation after cardiac death

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继发性甲状旁腺功能亢进患者的乳糜泻

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世界核心医学期刊文摘（胃肠病学分册） 2005年第7期1卷 60-61页

作者： jorde R. saleh F. sundsfjord J. 程欣 Medical Department B University Hospital of North Norway NO-9038 Tromsφ Norway

Objective. Coeliac disease (CD) may present in its clas sical form with diarrhoea and weight loss, but also with atypical symptoms th at are both related and unrelated to malabsorption. Osteomalacia or osteopenia f ollowing malabsorption of calcium and vitamin D is known to occur in patients wi th CD, and in such cases secondary hyperparathyroidism(sHP) caused by low serum calcium levels is frequently found. However, the prevalence of CD in subjects wi th sHP has not been reported. Material and methods. In the Troms study 2001, ser um parathyroid hormone (PTH) and calcium were measured in 7954 subjects of whom 6061 were eligible for follow- up. From this group, 97 subjects with sHP (serum PTH ≥ 6.5 pmol/l and serum calcium subj ects were re- examined with serological tests for CD (antitissue transglutamina se, anti- gluten IgA and IgG). Results. CD was diagnosed in 4 subjects, all fro m the original sHP group. At the re- examination, only 29 of the 97 subjects wi th sHP still had elevated serum PTH levels. Among these were 3 of the subjects w ith CD. When grouping the serological test results as negative, borderline or po sitive, there was a significant difference between the sHP group and the control s for anti- tissue transglutaminase and anti- gluten IgA (p sio ns. subjects with sHP, at least when sHP is persistent, should be tested for CD.

关键词：乳糜泻吸收不良骨质缺乏不典型症状骨质软化症甲状旁腺素血清钙谷蛋白患者群血清学

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