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Low T3 vs low T3T4 euthyroid sick syndrome in septic shock patients:A prospective observational cohort study

World Journal of Critical Care Medicine 2024年第3期13卷 53-62页

作者： Mirza Kovacevic Visnja Nesek-adam Semir Klokic Ekrema Mujaric Department of Anesthesiology Resuscitation and Intensive CareCantonal HospitalZenica 72000Bosnia and Herzegovina Department of Anesthesiology Resuscitation and Intensive CareClinical Hospital Sveti DuhZagreb 10000Croatia gruppenpraxis General Practitioner's OfficeLaufen 4242Switzerland Department of Internal Diseases Cantonal HospitalZenica 72000Bosnia and Herzegovina

BACKgROUND Both phases of euthyroid sick syndrome(ESS)are associated with worse prognosis in septic shock *** there are still no indications for supplementation therapy,there is no evidence that both phases(initial and prolonged)are adaptive or that only prolonged is maladaptive and requires *** To analyze clinical,hemodynamic and laboratory differences in two groups of septic shock patients with *** A total of 47 septic shock patients with ESS were divided according to values of their thyroid hormones into low T3 and low T3T4 *** analysis included demographic data,mortality scores,intensive care unit stay,mechanical ventilation length and 28-day survival and laboratory with *** The Simplified Acute Physiology Score II score(P=0.029),dobutamine(P=0.003)and epinephrine requirement(P=0.000)and the incidence of renal failure and multiple organ failure(MOF)(P=0.000)were significantly higher for the low ***(P=0.047),neutrophilia(P=0.038),lymphopenia(P=0.013)and lactatemia(P=0.013)were more pronounced on T2 for the low T3T4 group compared to the low T3 *** blood pressure at T0(P=0.017)and T1(P=0.007),as well as mean arterial pressure at T0(P=0.037)and T2(P=0.033)was higher for the low T3 *** The low T3T4 population is associated with higher frequency of renal insufficiency and MOF,with worse laboratory and hemodynamic *** findings suggest potentially maladaptive changes in the chronic phase of septic shock.

关键词： Septic shock Euthyroid sick syndrome Low T3 Low T3T4 Intensive care unit

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Stroke Patients’ Reintegration into Normal Living Post-Discharge from Inpatient Rehabilitation: An Integrative Review

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Open Journal of Therapy and Rehabilitation 2024年第3期12卷 274-300页

作者： Eric F. Tanlaka Omotunmise Agbeyangi adam Mulcaster Edward Cruz Faculty of Nursing University of Windsor Windsor ON Canada Leddy Library University of Windsor Windsor ON Canada

Background: Stroke rehabilitation professionals have historically focused rehabilitation on physical functions and overlooked the concept of community reintegration after discharge from inpatient rehabilitation. The lack of focus on psychosocial functions post-stroke may lead to lower levels of satisfaction during community reintegration. Methods: This integrative review synthesized findings from research literature on stroke patients’ reintegration into the community after inpatient rehabilitation to address three research questions: a) What specific physical and psychosocial functions have been identified as predictors of successful reintegration into normal living after stroke?, b) How do physical and psychosocial functions promote successful reintegration into normal living after stroke?, and c) What factors have been identified that hinder stroke patients’ reintegration into normal living after stroke? Results: A systematic search of literature identified sixteen studies that provided significant context for the research questions. What physical and psychosocial functions of stroke patients included, for example, improved mobility, independence in daily activities, reduced disability, psychological well-being, self-efficacy, social support, and personal relationships. How physical and psychosocial functions promote reintegration included, for example, disability management, emotional well-being, self-care independence, sense of purpose, and employment influence. Factors that hinder stroke patients’ reintegration consisted of longer stride time, impaired balance/mobility, activities limitation, severe stroke, presence of comorbidity, depressive symptoms, speech and language challenges, inadequate self-efficacy, fear of falling, older age, low educational level, lack of social support, and social isolation. Conclusion: Successful community reintegration after stroke requires a shift of focus from rehabilitation interventions that target physical functions to incl

关键词： Stroke Outpatient Rehabilitation Community Reintegration Normal Living Functional Abilities

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Fault Location Method for Overhead Feeders with Distributed generation Units Based on Direct Load Flow Approach

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Journal of Modern Power Systems and Clean Energy 2024年第4期12卷 1135-1146页

作者： Charalampos g.Arsoniadis Vassilis C.Nikolaidis Department of Electrical and Computer Engineering Democritus University of ThraceXanthi 67100Greece

This paper proposes a novel fault location method for overhead feeders,which is based on the direct load flow *** method is developed in the phase domain to effec-tively deal with unbalanced network conditions,while it can al-so handle any type of distributed generation(Dg)units without requiring equivalent *** utilizing the line series parame-ters and synchronized or unsynchronized voltage and current phasor measurements taken from the sources,the method reli-ably identifies the most probable faulty *** the aid of an index,the exact faulty section among the multiple candi-dates is *** simulation studies for the IEEE 123-bus test feeder demonstrate that the proposed method accu-rately estimates the fault position under numerous short-circuit conditions with varying pre-fault system loading conditions,fault resistances,and measurement *** proposed meth-od is promising for practical applications due to the limited number of required measurement devices as well as the short computation time.

关键词： Fault location distribution system direct load flow distributed generation

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Comparative measurement of CO_(2),CH_(4)and CO at two traffic interjunctions having inflated vehicular flow in Delhi

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Journal of Environmental Sciences 2024年第7期141卷 314-329页

作者： Komal Daya Soni Khem Singh Shankar g.Aggarwal CSIR-National Physical Laboratory Dr.K.S.Krishnan MargNew Delhi 110012India Academy of Scientific&Innovative Research(AcSIR) Ghaziabad 201002India

Vehicular emissions are considered one of the major anthropogenic sources of greenhouse gases and poor air quality in metropolitan *** study aims to see the correlation of CO_(2),CH_(4),and CO through monitoring over a period from December 2020 to October 2021 covering three seasons’winter,summer,and monsoon at two different traffic locations of Delhi having different traffic volumes,road patterns,and traffic *** annual average morning concentration of CO_(2),CH_(4)and CO was found(533±105),(7.3±3.1),(10.7±3.0)ppm at Najafgarh and(480±70),(5.2±1.8),(7.8±2.8)ppm at Rajendra Place,respectively.A relationship between concentration of all three gases and meteorological parameters such as temperature,humidity,wind speed and wind direction has also been investigated using Pearson correlation coefficient and pollution rose diagram.A comparable pattern in concentration was observed for all three gases in spatial(location)and temporal(diurnal)*** concentration trend of CO_(2)in different seasons is winter>summer>monsoon,while in the case of CH_(4)winter=summer>monsoon but not any seasonal trend was noted in CO *** is observed that CO_(2)has a good relation with CO(a tracer for vehicular emission)in terms of diurnal variation,whereas,CH_(4)does not represent a relation with CO and CO_(2)diurnally,suggesting that vehicles are the source of CO_(2)but not much contributing to other greenhouse gases like CH_(4).

关键词： Vehicular emission greenhouse gases Harmful pollutants Meteorological parameters

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Study of hybrid nanofluid flow in a stationary cone-disk system with temperature-dependent fluid properties

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 677-694页

作者： A.S.JOHN B.MAHANTHESH g.LORENZINI Center for Mathematical Needs Department of MathematicsCHRIST(Deemed to be University)Karnataka 560029India School of Mathematical and Statistical Sciences The University of Texas Rio Grande ValleyTexas 78539U.S.A. Department of Engineering and Architecture University of ParmaParma 43124Italy

Cone-disk systems find frequent use such as conical diffusers,medical devices,various rheometric,and viscosimetry *** this study,we investigate the three-dimensional flow of a water-based Ag-Mg O hybrid nanofluid in a static cone-disk system while considering temperature-dependent fluid *** the variable fluid properties affect the dynamics and heat transfer features is studied by Reynolds's linearized model for variable viscosity and Chiam's model for variable thermal *** single-phase nanofluid model is utilized to describe convective heat transfer in hybrid nanofluids,incorporating the experimental *** model is developed as a coupled system of convective-diffusion equations,encompassing the conservation of momentum and the conservation of thermal energy,in conjunction with an incompressibility condition.A self-similar model is developed by the Lie-group scaling transformations,and the subsequent self-similar equations are then solved *** influence of variable fluid parameters on both swirling and non-swirling flow cases is ***,the Nusselt number for the disk surface is *** is found that an increase in the temperature-dependent viscosity parameter enhances heat transfer characteristics in the static cone-disk system,while the thermal conductivity parameter has the opposite effect.

关键词： hybrid nanofluid cone-disk system laminar flow variable fluid property Nusselt number

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Optimal Control of Service Rates of Discrete-Time(s,Q)Queueing-Inventory Systems with Finite Buffer

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Journal of Systems Science and Systems Engineering 2024年第3期33卷 261-280页

作者： L.Iniya B.Sivakumar g.Arivarignan School of Mathematics Madurai Kamaraj UniversityMaduraiTamilnaduIndia Department of Statistics Manonmaniam Sundaranar UniversityTirunelveliTamilnaduIndia

This article,we develop an optimal policy to control the service rate of a discrete time queueing-inventory system with finite *** customers arrive according to a Bernoulli process and the service time for the customers are *** the buffer size attains its maximum,any arriving new customers are considered to be *** customers are served one by one according to FCFS rule and each customers request random number of *** inventory is replenished according to a(s,Q)inventory policy with geometric lead *** main objectives of this article are to determine the service rates to be employed at each slot so that the long run expected cost rate is minimized for fixed inventory level and fixed buffer size and to minimize the expected waiting time for a fixed inventory level and fixed buffer *** problems are modelled as Markov decision *** establish the existence of a stationary policy and employ linear programming method to find the optimal service *** provide some numerical examples to illustrate the behaviour of the model.

关键词： Queueing-inventory system discrete time batch demand-Markov decision process

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The great catastrophe: causes of the Permo-Triassic marine mass extinction

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National Science Review 2024年第1期11卷 37-50页

作者： Paul B.Wignall David P.g.Bond School of Earth & Environment University of Leeds School of Environmental Sciences University of Hull

The marine losses during the Permo-Triassic mass extinction were the worst ever experienced. All groups were badly affected, especially amongst the benthos(e.g. brachiopods, corals, bryozoans, foraminifers,ostracods). Planktonic populations underwent a fundamental change with eukaryotic algae being replaced by nitrogen-fixing bacteria, green-sulphur bacteria, sulphate-reducing bacteria and prasinophytes. Detailed studies of boundary sections, especially those in South China, have resolved the crisis to a ～55 kyr interval straddling the Permo-Triassic boundary. Many of the losses occur at the beginning and end of this interval painting a picture of a two-phase extinction. Improved knowledge of the extinction has been supported by numerous geochemical studies that allow diverse proposed extinction mechanisms to be studied. A transition from oxygenated to anoxic-euxinic conditions is seen in most sections globally, although the intensity and timing shows regional variability. Decreased ocean ventilation coincides with rapidly rising temperatures and many extinction scenarios attribute the losses to both anoxia and high *** kill mechanisms include ocean acidification for which there is conflicting support from geochemical proxies and, even less likely, siltation(burial under a massive influx of terrigenous sediment) which lacks substantive sedimentological evidence. The ultimate driver of the catastrophic changes at the end of the Permian was likely Siberian Trap eruptions and their associated carbon dioxide emissions with consequences such as warming, ocean stagnation and acidification. Volcanic winter episodes stemming from Siberian volcanism have also been linked to the crisis, but the short-term nature of these episodes(g evidence for rapid warming during the crisis makes this an unlikely cause. Finally, whilst the extinction is well studied in equatorial latitudes, a different history is found in northern Boreal latitudes

关键词： ocean anoxia ocean acidification siltation productivity collapse volcanic winter

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Photometric and Spectroscopic Study of Ten Low Mass Ratio Contact Binary Systems:Orbital Stability,O'Connell Effect and Infrared Calcium Line Filling

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Research in Astronomy and Astrophysics 2024年第8期24卷 212-222页

作者： Surjit S.Wadhwa adam Popowicz Raúl Michel Petar Kostić Oliver Vince Nick F.H.Tothill Ain Y.De Horta Miroslav D.Filipović School of Science Western Sydney UniversityLocked Bag 1797PenrithNSW 2751Australia Department of Electronics Electrical Engineering and MicroelectronicsSilesian University of TechnologyAkademicka 1644120 GliwicePoland Instituto de Astronomía UNAM.A.P.87722800 EnsenadaBCMéxico Astronomical Observatory Volgina 711060 BelgradeSerbia

Low mass ratio contact binary systems are more likely to have unstable orbits and potentially *** addition,such systems exhibit characteristics such as starspots and high energy emissions(UV)suggestive of chromospheric and magnetic *** curve modeling of ten contact binary systems is *** were found to be of extreme low mass ratio ranging from 0.122 to 0.24 and three were found to be potentially unstable and possible merger *** of the infrared calcium absorption lines is a marker of increased chromospheric *** use the available Large Sky Area Multi-Object Fiber Spectroscopic Telescope spectra along with matched standard spectra(broadened for rotation)to measure the excess filling of the central core depression flux of the two main infrared calcium absorption linesλ8542 andλ*** find that all reported contact binaries have excess filling of the core flux in the infrared calcium *** of the systems reported were also observed by the galaxy Evolution Explorer mission and we find that all three have features of excess ultraviolet emissions further adding evidence for increased chromospheric activity in low mass ratio contact *** of both orbital stability and absorption line filling is dependent on the determination of geometric and absolute parameters from light curve *** an insignificant number of contact binary light curves exhibit the O’Connell effect,usually attributed to *** discuss the inclusion of starspots in light curve solutions and how they influence the geometric and absolute parameters.

关键词： (stars)binaries eclipsing-techniques photometric-stars chromospheres

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Neutrophils in the tumor microenvironment-when a company becomes a crowd

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Cellular & Molecular Immunology 2024年第4期21卷 313-314页

作者： Zvi g.Fridlender Zvi granot Faculty of Medicine Hebrew University of JerusalemJerusalemIsrael Institute of Pulmonary Medicine Hadassah-Hebrew University Medical Center91120 JerusalemIsrael Department of Developmental Biology and Cancer Research Institute for Medical Research Israel CanadaFaculty of MedicineHebrew University91120 JerusalemIsrael

Traditionally,neutrophils are perceived as terminally differentiated cells with defined functions and limited *** is commonly believed that circulating,marginating and tissue-infiltrating neutrophils belong to the same homogeneous population and are capable of switching between these *** research has stagnated since the early 1980s,maintaining a narrow and simplistic view of their capabilities.

关键词： narrow infiltrating differentiated

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Silicon quantum dots-based fluorescent sensor for the detection of cobalt with high sensitivity and selectivity

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Chinese Chemical Letters 2024年第1期35卷 451-455页

作者： Ebtihaj Mohammed Sullam Khalid Mohammed adam Juanjuan Liu Hongli Chen Jianxi Xiao State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhou 730000China Department of Chemistry Faculty of EducationUniversity of KordofanEl Obeid 51111Sudan

Fluorescent silicon quantum dots(Si QDs)were hydrothermally synthesized from a mixture of 3(2-aminoethylamino)propyl(dimethoxymethylsilane)(AEAPDMMS)and poly(vinylpyrrolidine)(PVP).The resulting Si QDs exhibited good water solubility and high *** the optimized conditions,the probe revealed an excellent linear fluorescence quenching effect on Co2+ranging from 1μmol/L to 120μmol/L with a limit of detection of 0.37μmol/L(based on 3 s/k).The quenching mechanism was studied,showing that static quenching(SQE)causes the main ***,the test paper based on Si QDs was prepared,which is cost-effective,high sensitivity,good selectivity,easy to use and show excellent anti-interference *** method was applied to analyze the content of Co2+in environmental water samples with satisfying results.

关键词： Silicon quantum dots Fluorescence Poly(vinylpyrrolidine) Test paper Cobalt detection

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