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Impact of a physical activity program on plasma concentrations of adiponectin, leptin and ghrelin in overweight and obese schoolchildren: A randomized controlled trial

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Health 2013年第11期5卷 1819-1828页

作者： Andre Everton de Freitas Joel Alves Lamounier Danusa Dias Soares Thiago Henrique de Oliveira Debora Romualdo Lacerda Joyce Batista Andrade Flavia Komatsuzaki Leida Maria Botion adaliene versiani matos ferreira Camilo Adalto Mariano da Silva Dilermando Fazito Rezende Graduate Program in Child and Teenager Health Medicine SchoolFederal University of Minas GeraisBelo HorizonteBrazil Faculty of Health and Human Ecology Medicine SchoolVespasianoBrazil Graduate Program in Health Sciences Medicine SchoolFederal University of Sao Joao Del ReiCampus MidwestDivinopolisBrazil Laboratory of Exercise Physiology Federal University of Minas GeraisBelo HorizonteBrazil Laboratory of Metabolism Federal University of Minas GeraisBelo HorizonteBrazil School of Nursing Federal University of Minas GeraisBelo HorizonteBrazil School of Nutrition Federal University of Ouro PretoOuro PretoBrazil Faculty of Medicine Barbacena BarbacenaBrazil

Introduction: Child obesity has important consequences on the child’s health and is related to the risk of developing chronic diseases. That brings up the need for research assessing the impact of obesity-and overweight-reduction programs with close attention to methodology aspects and precise indicators of the impact of such programs. Goal: Assessing the impact of a physical activity program on the plasma concentrations of adiponectin, leptin, and ghrelin in overweight and obese schoolchildren. Methods: Randomized controlled trial, double-blind, with 6-to 9-year-old overweight and obese school-children. A sample of 79 schoolchildren randomly distributed into control and intervention groups was subjected to a physical activity program. The levels of adiponectin, leptin, ghrelin, body mass index, body fat percentage, anthropometry, lipid profile and glycemia were evaluated. The program’s impact was assessed through multivariate linear regression models. Result: When comparing the groups, a significant difference was found for adiponectin, which shows an increase in the proportion of subjects with higher adiponectin concentrations for the intervention group and a reduction in body mass index and body fat percentage. Conclusion: The impact of the intervention program was positive in increasing adiponectin levels associated with a reduction in body mass index and body fat percentage.

关键词： Obesity Overweight Schoolchildren Physical Activity Adipocitokines

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Combined Oxidative Phosphorylation Deficiency-20-Exome as a Diagnostic Implement

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Journal of Biosciences and Medicines 2024年第6期12卷 7-12页

作者： Paulo Roberto matos-Neto Lucas Antonissen Lima Verde Airton ferreira da Ponte-Filho Luís Eduardo Oliveira matos Amandha Espavier Trés Paulo Roberto Lacerda Leal Gerardo Cristino-Filho Regina Coeli de Carvalho Porto Carneiro Faculty of Medicine Federal University of Cear Sobral Cear Brazil Department of Neurosurgery Federal University of Cear Sobral Cear Brazil Department of Neuropediatrics Federal University of Cear Sobral Cear Brazil

Mitochondrial disorders are phenotypically varied, with serious clinical repercussions. Among them, there is the deficiency of combined oxidative phosphorylation of type 20, which occurs due to a defect in the VARS2 gene. This article presents a case of a 2-year-old female with progressive myoclonic epilepsy and psychomotor regression, with refractoriness to multiple anticonvulsants. The diagnosis was only made after the examination was carried out. Therefore, this article highlights the aspects of this rare disease and the importance of the exome for the diagnosis of rare conditions.

关键词： Oxidative Phosphorylation Epilepsy Exome Mitochondrial Defect VARS2

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Timing of Proterozoic magmatism in the Sunsas belt, Bolivian Precambrian Shield, SW Amazonian Craton

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Geoscience Frontiers 2021年第6期12卷 277-293页

作者： Ingrid M.Nedel Reinhardt A.Fuck Amarildo S.Ruiz Gerardo R.matos-Salinas Alanielson da C.D.ferreira Instituto de Geociências Universidade de Brasília(UnB)Brasília-DFBrazil Faculdade de Geociências Universidade Federal de Mato GrossoCuiabá-MTBrazil Instituto de Investigaciones Geológicas y del Medio Ambiente Universidad Mayor de San Andrés(UMSA)Pabellón GeologíaCalle 27Campus Universitario Cota CotaLa PazBolivia Department of Earth Sciences Stellenbosch UniversityPrivate Bag X1Matieland7602 StellenboschSouth Africa

We present new U–Pb zircon and monazite ages from the Sunsas belt granitic magmatism in Bolivia, SW Amazonian Craton. The geochronological results revealed four major magmatic events recorded along the Sunsas belt domains. The older igneous event formed a granitic basement coeval to the Rio Apa Terrane(1.95–1.85 Ga) in the southern domain. The second magmatic episode is represented by 1.68 Ga granites associated to the Paraguá Terrane(1.69–1.66 Ga) in the northern domain. The 1.37–1.34 Ga granites related to San Ignacio orogeny represent the third and more pervasive magmatic event, recorded throughout the Sunsas belt. Moreover, magmatic ages of ~1.42 Ga revealed that the granitogenesis associated to the Santa Helena orogeny also affected the Sunsas belt, indicating that it was not restricted to the Jauru Terrane. Lastly, the 1.10–1.04 Ga youngest magmatism was developed during the Sunsas orogeny and represents the final magmatic evolution related to Rodinia assembly. Likewise, the 1.95–1.85 and 1.68 Ga inherited zircon cores obtained in the ~1.3 Ga and 1.0 Ga granite samples suggest strong partial melting of the Paleoproterozoic sources. The 1079 ± 14 Ma and 1018 ± 6 Ma monazite crystallization ages can be correlated to the collisional tectono-thermal event of the Sunsas orogeny, associated to reactions of medium-to high-grade metamorphism. Thus, the Sunsas belt was built by heterogeneous 1.95–1.85 Ga and 1.68 Ga crustal fragments that were reworked at 1.37–1.34 Ga and 1.10–1.04 Ga related to orogenic collages. Furthermore, the 1.01 Ga monazite age suggests that granites previously dated by zircon can bear evidence of a younger thermal history. Therefore, the geochronological evolution of the Sunsas belt may have been more complex than previously thought.

关键词： SW Amazonian Craton Sunsas belt U–Pb geochronology Zircon Monazite

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A multi-integrated approach on toxicity effects of engineered TiO2 nanoparticles

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Frontiers of Environmental Science & Engineering 2015年第5期9卷 793-803页

作者： Ana PICADO Susana M. PAIXAO Liliana MOITA Luis SILVA Mario S. DINIZ Joana LOURENCO Isabel PERES Luisa CASTRO Jose Brito CORREIA Joana PEREIRA Isabel ferreira Antonio Pedro Alves matos Pedro BARQUINHA Elsa MENDONCA LNEG-National Laboratory of Energy and Geology I.P. Lisbon 1649-038 Portugal REQUIMTE Chemistry Department Fine Chemistry and Biotechnology Center Faculty of Sciences and Technology New University of Lisbon Caparica 2829-516 Portugal IMAR-Ocean Institute Department of Sciences and Environmental Engineering Faculty of Sciences and Technology New University of Lisbon Caparica 2829-516 Portugal CENIMAT/I3N and Department of Materials Science Faculty of Sciences and Technology New University of Lisbon Caparica 2829-516 Portugal Pathological Anatomy Curry Cabml Hospital Lisbon 1069-166 Portugal CESAM Faculty of Sciences Lisbon University Lisbon 1749-016 Portugal

The new properties of engineered nanoparti- cles drive the need for new knowledge on the safety, fate, behavior and biologic effects of these particles on organisms and ecosystems. Titanium dioxide nanoparticles have been used extensively for a wide range of applica- tions, e.g, self-cleaning surface coatings, solar cells, water treatment agents, topical sunscreens. Within this scenario increased environmental exposure can be expected but data on the ecotoxicological evaluation ofnanoparticles are still scarce. The main purpose of this work was the evaluation of effects of TiO2 nanoparticles in several organisms, covering different trophic levels, using a battery of aquatic assays. Using fish as a vertebrate model organism tissue histological and ultrastructural observations and the stress enzyme activity were also studied. TiO2 nanoparticles （Aeroxide~ P25）, two phase composition ofanatase （65%） and rutile （35%） with an average particle size value of 27.64-11 nm were used. Results on the ECs0 for the tested aquatic organisms showed toxicity for the bacteria, the algae and the crustacean, being the algae the most sensitive tested organism. The aquatic plant Lemna minor showed no effect on growth. The fish Carassius auratus showed no effect on a 21 day survival test, though at a biochemical level the cytosolic Glutathione-S-Transferase total activity, in intestines, showed a general significant decrease （p〈0.05） after 14 days of exposure for all tested concentrations. The presence of TiO2 nanoparticles aggregates were observed in the intestine lumen but their internalization by intestine cells could not be confirmed.

关键词： ecotoxicity enzymatic analysis histology,transmission electron microscopy (TEM) TiO2-nanoparti-cles

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Grain-size end-members and environmentally sensitive grain-size components: A comparative study in the mud shelf depocenters off southern Brazil

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International Journal of Sediment Research 2021年第2期36卷 317-327页

作者： Michel Michaelovitch de Mahiques Samara Cazzoli y Goya Maria Carolina da Silva Nogueira de matos Rodrigo Augusto Udenal de Oliveira Bianca Sung Mi Kim Paulo Alves de Lima ferreira Rubens Cesar Lopes Figueira Marcia Caruso Bícego Oceanographic Institute University of S?o Paulo Pra?a do Oceanográfico Institute of Energy and Environment University of S?o Paulo Avenida Professor Luciano Gualberto

The current study aims to do a comparative analysis of the results obtained with two End-Member(EM)grain-size modeling techniques(Analy Size and Bas EMMA) and the Environmental Sensitive Grain-Size(ESGS) modeling for sediment samples collected in the mudbelts of the southern Brazilian shelf. The methods were compared using grain-size data from the south Brazilian shelf, and the results are discussed here. It is the first time that the concept of ESGS, in its present form, is utilized outside China. The results show that despite its relative ease of use, the ESGS is not fully comparable to the EM analyses, and only two grain-size ESGS classes were recognized as analogous to EMs. The comparison of the Analy Size and Bas EMMA procedures also revealed significant differences between the techniques. A comparative analysis between the two EM techniques revealed advantages in the Bas EMMA, especially in the better correlation of the end-members with the original grain size distribution. The analysis of the geographical distribution of the EM abundances allowed point sources of sandy populations to be recognized as well as the contribution of the Rio de la Plata as a source of silty sediments to be inferred.

关键词： Grain-size End-member Environmentally sensitive Mudbelt Continental shelf

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The Performance of the School Psychologist in Schools for the Inclusion of Autistic Students in the Scenario of COVID-19

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Psychology Research 2023年第2期13卷 60-74页

作者： Vinicius Cutrim ferreira Pollianna Galvão Soares de matos Daniel Carvalho de matos Francidalma Soares Sousa Carvalho Filha Universidade Ceuma São LuísBrazil Instituto Evoluir São LuísBrazil Universidade Federal do Maranhão São LuísBrazil Universidade Estadual do Maranhão São LuísBrazil

During COVID-19,the repercussions on scholar dynamics,functioning and structure were inevitable,causing an impact on groups that,historically,are minority in relation to the scope of school inclusion policies,such as students diagnosed with autism spectrum disorder(ASD).This scenario is followed by educational phenomena in the face of which School Psychology has collaborated with the advancement of research and knowledge *** qualitative study,based on Historical-Cultural Psychology and Critical School Psychology,analyzed the role of the school psychologist in monitoring students diagnosed with ASD in the context of regular school during the *** following procedures were conducted:application of an online questionnaire;and semi-structured interviews with four school *** a result,three zones of shared meanings were built:the claim for the right to education with support and adaptations;the psychologist as the great savior of inclusion;the non-total inclusion that denounces the structure of injustice by *** information suggests that professional performance was hampered by different obstacles in the pandemic,such as the difficulty imposed by school,overload of demands,and impasses in the implementation of inclusion historically experienced at school,revealing that the school structure still carries historical consequences of *** shared meanings have demanded a professional performance with more effort,resistance,and strategies that accept the demands of school inclusion,providing collective mobilization,together with school actors,capable of breaking down barriers,especially those related to capacitist concepts.

关键词： school psychology autism spectrum disorder school inclusion pandemic

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Comparing the Behavior of Reinforced Concrete Columns Embedded in Walls and Subjected to Fire

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Journal of Civil Engineering and Architecture 2022年第7期16卷 354-361页

作者： Bruno Carvalho Lima de Alencar matos Fernando Luis da Silva ferreira João Paulo Correia Rodrigues Rodrigo Barreto Caldas Department of Civil Engineering University of CoimbraCoimbra 3030-788Portugal Department of Civil Engineering Federal University of Minas GeraisBelo Horizonte-MG 31270-901Brazil

Fire is an exceptional action that may occur during the life of a ***,it must be considered when designing a building *** standards provide several types of design methods for that propose,used for single elements,parts of structure or the structure as a *** fire design of columns is important both for new project as for remodel buildings and also for verification of the residual resistance of columns that have suffered a fire *** this way,the aim of this work is to analyze numerically different ways of fire exposure to check the compressive strength of the columns when subjected to fire and the influence of the adjacent walls to a column in case of *** thermal advanced analysis of the sections columns was performed using the finite element software,Abaqus CAE,where the standard fire curve,ISO 834(International Organization for Standardization 834),was used,with 4 h of fire *** was possible,with the two methods used in this work,to compare them to verify which model is more conservative and which is closer to the advanced numerical model,for calculating temperatures in the column *** was checked that the walls act as thermal insulators,protecting part of the columns from the convection and radiation of the ***,the effects of raising the temperature over the compressive resistance of the reinforced concrete column,were reduced.

关键词： Column reinforced concrete thermomechanical analysis fire

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A High-Resolution Modeling Strategy to Assess Impacts of Climate Change for Mesoamerica and the Caribbean

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American Journal of Climate Change 2016年第2期5卷 202-228页

作者： Robert Oglesby Clinton Rowe Alfred Grunwaldt Ines ferreira Franklyn Ruiz Jayaka Campbell Luis Alvarado Francisco Argenal Berta Olmedo Alejandro del Castillo Pilar Lopez Edwards matos Yosef Nava Carlos Perez Joel Perez Department of Earth and Atmospheric Sciences University of Nebraska Lincoln NE USA Climate Change and Sustainability Division Inter-American Development Bank Washington DC USA Instituto de Hidrología Meteorología y Estudios Ambientales de Colombia Bogota Colombia University of the West Indies Kingston Jamaica Instituto Meteorológico Nacional Costa Rica San Jose Costa Rica Servicio Meteorológico Nacional de Honduras Dirección General de Aeronáutica Civil Tegucigalpa Honduras Empresa de Transmisión Eléctrica Paname?a Ciudad de Panamá Panamá Water Center for the Humid Tropics of Latin America and the Caribbean (CATHALAC) Ciudad de Panamá Panamá Unidad de Análisis Meteorológico Empresa de Transmisión Eléctrica Paname?a Ciudad de Panamá Panamá Instituto Nacional de Ecología y Cambio Climático Mexico City Mexico National Weather Service MARN San Salvador El Salvador

Mesoamerica and the Caribbean are low-latitude regions at risk for the effects of climate change. Global climate models provide large-scale assessment of climate drivers, but, at a horizontal resolution of 100 km, cannot resolve the effects of topography and land use as they impact the local temperature and precipitation that are keys to climate impacts. We developed a robust dynamical downscaling strategy that used the WRF regional climate model to downscale at 4 - 12 km resolution GCM results. Model verification demonstrates the need for such resolution of topography in order to properly simulate temperatures. Precipitation is more difficult to evaluate, being highly variable in time and space. Overall, a 36 km resolution is inadequate;12 km appears reasonable, especially in regions of low topography, but the 4 km resolution provides the best match with observations. This represents a tradeoff between model resolution and the computational effort needed to make simulations. A key goal is to provide climate change specialists in each country with the information they need to evaluate possible future climate change impacts.

关键词： Regional Climate Models Dynamical Downscaling Strategy Mesoamerica and Caribbean Climate Change

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A Selection Process as a Game

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Management Studies 2018年第6期6卷 531-535页

作者： Manuel Alberto M.ferreira Maria Cristina Peixoto de matos Instituto Universitário de Lisboa(ISCTE-IUL) LisbonPortugal Instituto Politecnico de Viseu(IPV)-Escola Superior deTecnologia e Gestao de Viseu(ESTGV) ViseuPortugal

The aim of this paper is to exemplify how to solve the problem of selecting a candidate up to his/her acceptance trough game *** originality this paper proposes is how this problem will be approached:It will be treated as a single game which is made up of two parts,going as far as to state that the payoffs in the first part of the game will be the mediators of the second part of the game.

关键词： selection process game theory two-part game code form

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Treatment of systemic lupus erythematosus with intravenous immunoglobulin （ivIg） and its impact on cellular subsets and immunoregulation

Treatment of systemic lupus erythematosus with intravenous i...

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The 8th International Congress on SLE

作者： Luiz Fernando Goulart Clara Pereira Ana Monica Gabriel Barbara Leal Maria Francisca Fontes Carlos Vasconcelos Carlos M.ferreira Jorge Martins Joo matos-Costa Berta Martins António Marinho Margarida Lima Jocelyne Demengeot Constantin Fesel Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPort

＜正＞Purpose:Intavenous immunoglobulin（ivIg）,which has well-demonstrated beneficial effects in various autoimmune diseases,is used as a therapeutic option for Systemic Lupus Erythematosus（SLE）patients,particularly for those with poor responses to standard *** studied immune homeostasis and regulation in patients undergoing this

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