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顶泌汗腺囊肿伴含铁血黄素皮肤纤维瘤样基质2例

World Journal of Neuroscience（神经科学国际期刊） 2014年第5期

作者： Iria Rodriguez Constenla Antonio Pato Pato Icíar Cimas Hernando José Ramón Lorenzo gonzalez

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世界核心医学期刊文摘（皮肤病学分册） 2005年第6期1卷 42-42页

作者： gonzalez S. 崔荣 Dr. Department of Pathology Catholic University of Chile School of Medicine Lira 854PSantiago Chile

Two cases of an unusual cutaneous lesion characterized by a dermal nodule with apocrine gland cysts surrounded by a hemosiderotic dermatofibroma-like proliferating stroma are reported. The first case was a 52- year-old female who presented with a nodule on the back of several years of evolution and with the clinical diagnosis of lipoma; the second case was a 41year-old male who presented with a forehead nodule of several years of evolution with a clinical diagnosis of epidermal cyst. Histologically, an ill-delimited non-encapsulated nodule composed of cystic spaces and solid areas was found. The cystic spaces consisted of ductal structures and a bilayered epithelial covering with apocrine differentiation; the surrounding area showed a stroma composed of a mixture of both fibrocytes and macrophages and abundant hemosiderin granules;fociofrecent hemorrhages and a more dense fibrous stroma at the periphery with typical storiform areas were also visible. Both cases have shown a benign course without local recurrence in follow up until this report date.

关键词：顶泌汗腺皮肤纤维瘤含铁血黄素瘤样增生纤维细胞临床诊断近期出血间隔带巨噬细胞囊壁

Rare-Earth Doped GdVO₄ by Sol-Gel Method: Structural and Luminescence Properties

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World Journal of Engineering and Technology 2022年第4期10卷 907-922页

作者： D. Y. Medina-Velázquez A. D. J. Morales-Ramírez A. A. Morales-Hernández B. gonzalez L. Ramírez-García E. Garfías-García J. Oliva C. R. Garcia J. Reyes-Miranda M. A. Barron E. Osorio-de-la-Rosa Universidad Autónoma Metropolitana-Azcapotzalco Ciencias Básicas e Ingeniería Reynosa México Instituto Politécnico Nacional CIITEC IPN Cerrada de CECATI S/N Col. México City México Instituto Politécnico Nacional ESIQIE IPN México City México CONACyT-División de Materiales Avanzados Instituto Potosino de Investigación Científica y Tecnológica A. C. San Luis Potosí México Facultad de Ciencias Físico Matemáticas Universidad Autónoma de Coahuila Edif. A Unidad Camporredondo Saltillo México Comonfort Col. Del Bosque. C.P. 77019 Chetumal Quintana Roo México.6 CONACYT-Universidad Autónoma del Estado de Quintana Roo Boulevard Bahía s/n esq. Ignacio Chetumal México

Rare earths have been extensively developed in recent years, however, new hosts allow high excitation and emission efficiency, in this sense, gadolinium vanadate has been extensively studied and in previous works it has been widely used in down conversion systems. Because of the strong absorption of the VO4 groups and efficient energy transfer from GdVO4 to lanthanide ions, in this work its up-conversion properties were studied when is co-doped with Yb3+, X3+ where X = Tm, Er and Ho. The powders synthesized presented a high crystallinity and a rounded morphology and exhibit a high luminescence when are excited with IR radiation.

关键词： Gadolinium Rare Earths Up Convertion

Thyroid Nodule: Alpha Score 2.0 Classification for FNAB Selection, Multicentric Study in Latin America

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Open Journal of Radiology 2021年第4期11卷 160-174页

作者： Glenn Mena Maria Cristina Chammas Carlos Mario gonzalez Vasquez Lylian Rocío Villagómez Marco Alfredo Muñoz Pico Patricio Alejandro Montalvo Santiago Mena-Bucheli Julio Olmedo Elizabeth Quintero Pedro Henrique de Marqui Moraes Osmar Cassio Saito Hubertino Diaz Denise Romero Gabriela Velalcazar Angel Ramón Sosa Fleitas Yamil Oliver Quevedo Ontaneda Victor Ricardo Chara Alpha Imagen Radiología e Intervencionismo Quito Ecuador Hospital das Clínicas Faculdade de Medicina da Universidade de Sã o Paulo S&#227 o Paulo Brasil Hospital Pablo Tobón Uribe Medellin Colombia Hospital del Instituto Ecuatoriano de Seguridad Social Quito Sur Quito Ecuador Hospital San Francisco de Quito Quito Ecuador Hospital Edgardo Rebagliati Martins Lima Perú Hospital Carlos Andrade Marín Quito Ecuador Hospital de Clínicas San José de San Martín Buenos Aires Argentina Hospital Universitario de Los Andes Mérida Venezuela Hospital de la Policía Quito Ecuador Hospital Sisol Tacna Perú

Introduction: To perform a Latin-American multicentric study for the prediction of benign and malignant thyroid nodules using Alpha Score, and to compare it with ACR TIRADS® and Bethesda®. Materials and Methods: A prospective multicentric study in 10 radiological hospitals and institutions of Latin America was performed and 818 thyroid nodules were analyzed by ultrasound and classified by using both ACR TIRADS® and Alpha Score;fine-needle aspiration biopsy was performed when needed and classified with Bethesda. The relationships between predictors were analyzed by using binary logistic regression, statistical significance was defined by a p-value of 0.05, with an error margin of 4% and 95% confidence intervals. Results: Alpha Score 2.0 establishes five types of malignant predictors: microcalcifications, irregular borders, taller-than-wide shape, predominant solid texture and hypoechogenicity;a diameter equal to or greater than 1.5 cm adds an extra point to the final score. Resulting classification divides TNs into 4 categories: benign (1.9%), low suspicion (8.7%), mild suspicion (13.6%) and high suspicion (75.7%) of malignancy probability;sensitivity of 82%, specificity of 74%, the positive predictive value of 94%, the negative predictive value of 51%, the statistical accuracy of 81%, odds ratio of 108.89 and correlation with ACR TIRADS of 0.77 and Bethesda of 0.91. Conclusions: Alpha Score 2.0 has superior diagnostic accuracy and performance compared to the previously published Alpha Score and is able to classify a benign TN in a precise, safe and accurate way, avoiding unnecessary FNABs or determining the necessity of FNAB in cases of moderate to high suspicion of malignancy.

关键词： Thyroid Cancer-Clinical Radiology-Imaging Thyroid Nodule Alpha Score TIRADS® Thyroid Ultrasonography

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基于线性化技术的渗透压摩尔浓度测量系统

传感器与微系统 2012年第7期31卷 91-94页

作者：齐胜利李艳宁张立雄陈治 Dante J Dorantes-gonzale 傅星天津大学精密测试技术及仪器国家重点实验室天津300072

在冰点下降原理基础上,研究了渗透压摩尔浓度测量系统测量过程和参数设置问题。应用100μA恒流源供电方式法和二阶范数最小二乘法曲线拟合算法相结合,提出了NTC热敏电阻器线性化新方法,建立了NTC热敏电阻器的Matlab修正模型,实现了NTC... 详细信息

在冰点下降原理基础上,研究了渗透压摩尔浓度测量系统测量过程和参数设置问题。应用100μA恒流源供电方式法和二阶范数最小二乘法曲线拟合算法相结合,提出了NTC热敏电阻器线性化新方法,建立了NTC热敏电阻器的Matlab修正模型,实现了NTC热敏电阻器线性化处理。在此基础上,采用高分辨率A/D进行模拟信号转换,完成了渗透压摩尔浓度测量系统的设计。经实验验证,测量精度为±1 mmol/kg(≤500 mmol/kg)或RSD≤±0.2%(>500 mmol/kg)。

关键词：渗透压摩尔浓度桥式电路曲线拟合算法热敏电阻器

Role of magnetic field evolution on filamentary structure formation in intense laser–foil interactions

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High Power Laser Science and Engineering 2019年第1期7卷 99-106页

作者： M.King N.M.H.Butler R.Wilson R.Capdessus R.J.Gray H.W.Powell R.J.Dance H.Padda B.gonzalez-Izquierdo D.R.Rusby N.P.Dover G.S.Hicks O.C.Ettlinger C.Scullion D.C.Carroll Z.Najmudin M.Borghesi D.Neely P.McKenna SUPA Department of Physics University of Strathclyde Central Laser Facility STFC Rutherford Appleton Laboratory The John Adams Institute for Accelerator Science Blackett Laboratory Imperial College London Centre for Plasma Physics Queen's University Belfast

Filamentary structures can form within the beam of protons accelerated during the interaction of an intense laser pulse with an ultrathin foil target. Such behaviour is shown to be dependent upon the formation time of quasi-static magnetic field structures throughout the target volume and the extent of the rear surface proton expansion over the same *** is observed via both numerical and experimental investigations. By controlling the intensity profile of the laser drive,via the use of two temporally separated pulses, both the initial rear surface proton expansion and magnetic field formation time can be varied, resulting in modification to the degree of filamentary structure present within the laser-driven proton beam.

关键词： laser-plasma ion acceleration instabilities

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水牛感染肝片吸虫后肝脏组织的病理学变化

畜牧与兽医 1999年第6期31卷 1-3页

作者：杨倩毛卫华毛鑫智黄国庆 gonzalez-GallegoJ 南京农业大学动物医学院南京210095 西班牙莱昂大学生理药理毒理系莱昂24071

15 头水牛在人工感染条件下进行肝片吸虫感染, 慢性感染组水牛每天口服60 个囊蚴, 20 d 总共口服1 200 个囊蚴。急性感染组水牛1 次口服1 600 个囊蚴。慢性感染的水牛于感染后第26 周宰杀。急性感染的水牛分别于第10 , 13 , 16 和22 周... 详细信息

15 头水牛在人工感染条件下进行肝片吸虫感染, 慢性感染组水牛每天口服60 个囊蚴, 20 d 总共口服1 200 个囊蚴。急性感染组水牛1 次口服1 600 个囊蚴。慢性感染的水牛于感染后第26 周宰杀。急性感染的水牛分别于第10 , 13 , 16 和22 周宰杀。肝脏的组织病理学显示, 肝片吸虫幼虫可引起肝脏一系列炎症反应。急性感染后第10 周和13 周肝细胞变性、坏死, 肝小叶内淤血, 大量淋巴细胞浸润, 继而发展为肝索萎缩。急性感染后第22 周及慢性感染后第26 周, 汇管区内有大量结缔组织及新生的小胆管增生。实验表明慢性感染和急性感染肝片吸虫的水牛均可导致肝脏典型的病理学变化。

关键词：水牛肝片吸虫肝脏急性感染病理学

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M89酒店意大利米兰

世界建筑导报 2018年第5期33卷 80-83页

作者： luca lazzerotti mauro mandelli silvia calzetti alessandro leanti andrea sforzin carlos noriega daniel gonzalez santiago trujillo erica mensi federico simonetti gianluca iannotta niccolò genesio andrea martiradonna(摄) piuarch

M89酒店对面，是Caproni工厂规则排布的厂房，有着别样的棚屋顶，散发着工业考古学般的魅力。新建的M89四星级酒店，位于via Mecenate大街89号。酒店正对着百年前一大型飞机制造厂厂房，经过Piuarch精心改造和扩建，厂房现在已成为古驰... 详细信息

M89酒店对面，是Caproni工厂规则排布的厂房，有着别样的棚屋顶，散发着工业考古学般的魅力。新建的M89四星级酒店，位于via Mecenate大街89号。酒店正对着百年前一大型飞机制造厂厂房，经过Piuarch精心改造和扩建，厂房现在已成为古驰新总部大楼。

关键词：四星级酒店意大利米兰飞机制造厂厂房考古学 via 屋顶

基于构效关系研究吴茱萸主要活性成分对芳香烃受体的作用

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基于构效关系研究吴茱萸主要活性成分对芳香烃受体的作用

膳食中多氯联苯的摄入与高血压发病率的关系:一项西班牙队列研究

第三届全国药物代谢动力学青年科学家论坛暨刘昌孝人才奖颁奖大会

作者：张友波严婷婷孙冬雪张雷郑怡然谢岑杨秀伟 Frank J.gonzalez 北京大学药学院天然药物及仿生药物国家重点实验室美国国立卫生研究院代谢中心实验室沈阳药科大学中药学院

目的:研究吴茱萸碱,吴茱萸次碱及去氢吴茱萸碱对芳香烃受体的激活作用及构效关系。方法:应用小鼠原代肝细胞研究吴茱萸碱,吴茱萸次碱及去氢吴茱萸碱对芳香烃受体靶基因的表达调控作用;应用双荧光素酶报告基因实验结合分子对接技术和量... 详细信息

目的:研究吴茱萸碱,吴茱萸次碱及去氢吴茱萸碱对芳香烃受体的激活作用及构效关系。方法:应用小鼠原代肝细胞研究吴茱萸碱,吴茱萸次碱及去氢吴茱萸碱对芳香烃受体靶基因的表达调控作用;应用双荧光素酶报告基因实验结合分子对接技术和量子计算研究三个化合物对芳香烃受体激活作用;应用芳香烃受体野生型及敲除小鼠研究三个化合物在体内对芳香烃受体的影响。结果:吴茱萸次碱对芳香烃受体表现出极强的激活作用;三个化合物对芳香烃受体作用强弱顺序为:吴茱萸次碱>去氢吴茱萸碱>吴茱萸碱;14位N原子的立体构型是影响化合物作用强弱的关键因素;三个化合物在体内没有表现出明显的肝毒性。结论:本实验从结构方面阐明了吴茱萸碱,吴茱萸次碱及去氢吴茱萸碱对芳香烃受体激活的强弱作用,为研究吲哚喹啉类生物碱对芳香烃受体的激活机制提供了理论依据。

关键词：吴茱萸碱吴茱萸次碱去氢吴茱萸碱芳香烃受体构效关系

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中华高血压杂志 2015年第2期23卷 199-199页

作者： Donat-Vargas C Gea A Sayon-Orea C de la Fuente-Arrillaga C Martinez-gonzalez MA Bes-Rastrollo M 刘莉叶鹏

多氯联苯可通过食物链在生物体内蓄积，是一种持久性的食品有机污染物。有证据表明，接触多氯联苯与高血压发生呈正相关，但尚无前瞻性研究探索在成年人中的这种潜在联系。

关键词：多氯联苯高血压队列研究西班牙发病率膳食有机污染物体内蓄积