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Three Different Doses of Intrathecal Morphine as Part of a Multimodal Regimen for Post-Cesarean Delivery Analgesia: A Randomized Double-Blinded Trial

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Open Journal of Obstetrics and Gynecology 2018年第9期8卷 780-789页

作者： Marcio Luiz Benevides Rubens Jardim Nochi Jr. Carlos Eduardo Solcia Valter Moreira Xavier Júnior adalberto francisco buss lima Department of Anesthesiology Hospital Geral Universitário Cuiabá Brazil

Brazil is one of the countries that carry out cesarean delivery in the world. The pain after cesarean delivery (CD) is one of the main concerns of parturient. Intrathecal Morphine (ITM) is widely used for the treatment of pain after CD;however, the optimal dose with minimal side effects is to be established. Objectives: To compare the analgesia and side effects resulted by three different doses of ITM as part of a multimodal regimen for post-cesarean delivery analgesia. Methods: One hundred ninety-four patients were sampled in this randomized, double-blinded, three-arm study (group 0.075: ITM 0.75 mg;group 0.1: ITM 0.1 mg and group 0.15: ITM 0.15 mg). All patients received intravenous dexamethasone, dipyrone and ketoprofen. The primary endpoint was pain intensity measured at rest and on movement, while the secondary endpoint was overall satisfaction with pain relief, the incidence of nausea and vomiting, intensity of pruritus, and the use of additional tramadol, antipruritic and antiemetic use within 24 hours after postoperation. Results: The three groups showed similar pain intensity at rest and on movement. The pain intensity on movement was significantly higher than at rest in the groups (p 0.001). There were no significant differences among the groups regarding secondary endpoint. Conclusions: Our findings suggest that in cases of an elective CD, 0.075 mg of ITM produces postoperative analgesia of similar quality that provided by 0.1 or 0.15 mg ITM. The patients should have a multimodal analgesia approach that includes: ITM, anti-inflammatory agents and access to additional systemic analgesic if necessary.

关键词： Spinal Anesthesia Cesarean Delivery Intrathecal Morphine Postoperative Pain Multimodal Analgesia

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COMBINING SINGULAR SPECTRUM ANALYSIS AND PAR(p) STRUCTURES TO MODEL WIND SPEED TIME SERIES

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Journal of Systems Science & Complexity 2014年第1期27卷 29-46页

作者： MENEZES Moises lima de SOUZA Reinaldo Castro PESSANHA Jos francisco Moreira Department of Statistics Fluminense Federal University ( UFI~ Brazil. Email: moisesAima@msn.com.SOUZA Reinaldo Castro Electrical Engineering Department: Pontifical Catholic University of Rio de Janeiro (PUC-Rio) Brazil. Institute of Mathematics and Statistics State University of Rio de Janeiro (UERJ) Brazil.

Singular spectrum analysis （SSA） is a technique that decomposes a time series into a set of components, such as, trend, harmonics, and residuals. Leaving out the residual components and adding up the others, the time series can be smoothed. This procedure has been used to model Brazilian electricity consumption and flow series. The PAR（p）, periodic autoregressive models, has been broadly used in modelling energy series in Brazil. This paper presents an approach of this decomposition method, by fitting the PAR（p）, considering its multivariate version known as multivariate SSA （MSSA）. The method was applied to a vector of two wind speed series recorded at two locations in the Brazilian Northeast region. The obtained results, when compared to the univariate decomposition of each series, were far superior, showing that the spatial correlation between the two series were considered by MSSA decomposition stage.

关键词： MSSA periodic autoregressive model SSA wind speed series.

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Integrated risk management: a Petrobras application in offshore well construction safety to minimize critical emergency disconnections

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Petroleum Science 2018年第2期15卷 421-431页

作者： Claudio Benevenuto de Campos lima Pedro Esteves Aranha Jose francisco Tebaldi de Castro Gilson Brito Alves lima Augusto Borella Hougaz Felipe de Souza Terra Petrobras Department of Production Engineering Federal Fluminense University

In order to avoid mistakes and to save a great deal of time in analysis, an innovative methodology was developed that can analyze the well operations and rig characteristics involved to define the best emergency disconnect sequence （EDS） available. A solution was developed based on the characteristics of the rigs and blowout preventers （BOPs）, and six variables were considered that directly affect the choice of EDS. All possible combinations of 64 scenarios were analyzed, and the priority of choice of the EDS was defined empirically. This paper presents an approach to EDS risk management and examples of exposure time （time without riser safety margin and shear capability） for the same well, which can be lowered from 13% to 0.1%. The impact of this reduction is related to the ability of the BOP to cut some of the heavy casings, in addition to improved availability of EDS modes. This implementation opened up many possibilities for the performance of risk exposure analysis, enabling comparison of several BOP configurations of contracted rigs and selection of the best options. This innovative approach allowed a better management of the rig schedules, prioritizing safety aspects and making it possible to allocate the fleet in a systematic way.

关键词： Well safety Safety barriers Emergency disconnect sequence (EDS) Well control Kick Well design

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The Dog as a Risk Factor in Transmission of Visceral Leishmaniasis: A Review

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Advances in Infectious Diseases 2012年第2期2卷 37-47页

作者： francisco Assis lima Costa Department of Clinical Veterinary Medicine and Surgery Federal University of Piaui Teresina Brazil

Visceral leishmaniasis (VL) is a serious public health problem in Brazil and worldwide. Despite the euthanasia of dogs serologically positive, such action has not solved the endemic in Brazil. A risk area for VL involves the presence of the vector, the occurrence of canines and the record of human cases. The factors that have favored the persistence and spread of VL in Brazil are related to the predatory action of man on the environment, to the migratory movements and rural exodus, and a close coexistence of man and animals. Thus considering the epidemiological chain of VL, one fact seems clear: we do not know yet the true extent of the participation of the dog in the infectious cycle of VL. The clinical disease is an important indicator of the extent of the problem in an endemic area. The immunological events are complex and involve resistance and susceptibility to canine visceral leishmaniasis (CVL). One aspect in CVL is that many symptomatic dogs underwent xenodiagnosis not infect the vector. In such cases the pattern recognition receptors CD11b+, TLR2+, and NO present higher values for dogs with results in immunohistochemistry of skin and xenodiagnosis negative (IMH-/XENO-) than dogs with immunohistochemistry in skin and xenodiagnosis positive (IMH+/XENO+), suggesting that innate immunity modulates the competence of the dog to infect the vector. The organic response in CVL varies from individual to individual and within the same individual, with a strong evidence of being organ-specific. Only 20% of asymptomatic dogs have parasites in the skin and 15% are able to recover from clinical signs and eliminate the parasites spontaneously. In this review, we analyze the epidemiology of visceral leishmaniasis and clinical, immunological and pathological conditions that can contribute to understanding the role of dogs in transmission of visceral leishmaniasis.

关键词： Visceral Leishmaniasis Dog Epidemiology Pathology

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Existence and Multiplicity Results for a Class of Nonlinear Schrödinger Equations with Magnetic Potential Involving Sign-Changing Nonlinearity

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Analysis in Theory and Applications 2022年第2期38卷 148-177页

作者： francisco Odair de Paiva Sandra Machado de Souza lima Olimpio Hiroshi Miyagaki Departamento de Matematica UFSCarSao CarlosSP13560-970 Brazil Departamento de Ciencias Exatas Biologicas e da TerraINFES-UFFSanto Antonio de Padua-RJ28470-000Brazil

In this work we consider the following class of elliptic problems{−Δ_(A)u+u=a(x)|u|^(q−2)u+b(x)|u|^(p−2)u in R^(N),u∈H_(A)^(1)(R^(N)),(P)with 2 详细信息

In this work we consider the following class of elliptic problems{−Δ_(A)u+u=a(x)|u|^(q−2)u+b(x)|u|^(p−2)u in R^(N),u∈H_(A)^(1)(R^(N)),(P)with 2

关键词： Magnetic potential sign-changing weight functions Nehari manifold Fibering map

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Adenocarcinoma of the third and fourth portions of the duodenum: The capsule endoscopy value

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World Journal of Gastroenterology 2015年第31期21卷 9437-9441页

作者： Feliciano Chanana Paquissi Ana Henriqueta Filipe Bunga Pimentel lima Maria de Fátima do Nascimento Vieira Lopes francisco Viamontes Diaz Department of Medicine Clínica GirassolLuanda 1215Angola Service of Clinical Pathology Clínica GirassolLuanda 1215Angola Service of Gastroenterology Clínica GirassolLuanda 1215Angola Department of General Surgery Clínica GirassolLuanda 1215Angola

Primary adenocarcinoma of the small intestine occurs in over 50% of cases in the duodenum. However,its location in the third and fourth duodenal portions occurs rarely and is a diagnostic challenge. The aim of this work is to report an adenocarcinoma of the third and fourth duodenal portions,emphasizing its diagnostic difficulty and the value of video capsule endoscopy. A man,40 years old,with no medical history,with abdominal discomfort and progressive fatigue,presented four months ago with one episode o f m o d e ra t e m e l e n a. T h e p hy s i c a l e x a m i n a t i o n was normal,except for mucosal pallor. Blood tests were consistent with microcytic,hypochromic iron deficiency anemia with 7.8 g/d L hemoglobin. The upper and lower endoscopy were normal. Additional work-up with video capsule endoscopy showed a polypoid lesion involving the third and fourth portions o f t h e d u o d e n u m. B i o p s y s h o w e d a m o d e ra t e l y differentiated adenocarcinoma. Abdominal computed tomography showed a wall thickening from the third duodenal portion to the proximal jejunum,without distant metastasis. The patient underwent segmental resection(distal duodenum and proximal jejunum) with duodenojejunostomy. The surgical specimen histology confirmed the biopsy diagnosis,with transmural infiltration,without nodal involvement. Conclusion: Adenocarcinoma of the third and fourth portions of the duodenum is difficult to diagnose and capsule endoscopy is of great value.

关键词： Duodenum Duodenal cancer Adeno-carcinoma Endoscopy

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Autoregressive spatial analysis and individual tree modeling as strategies for the management of Eremanthus erythropappus

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Journal of Forestry Research 2016年第3期27卷 595-603页

作者： Henrique Ferraco Scolforo Jose Roberto Soares Scolforo Jose Marcio de Mello Anto nio Carlos Ferraz Filho Diogo francisco Rossoni Thiza Falqueto Altoe Antonio Donizette Oliveira Renato Ribeiro de lima Department of Forest Science Federal University of Lavras PO Box: 3037 Lavras MG 37200-000 Brazil Department of Statistics State University of Maringa Av. Colombo 5.790 Jd. Universitario Bloco E90 Maringa PR 87020-900 Brazil Department of Statistics Federal University of Lavras PO Box: 3037 Lavras MG 37200-000 Brazil

The objectives of this study were to apply statistical techniques to discriminate fertilization treatments of Eremanthus erythropappus（DC.） Mac *** autoregressive modeling, and to develop individual tree models for diameter and crown area（CA） projection to define management strategies for candeia plantations subjected to different fertilization treatments. This is an important tree species originating from the Brazilian Atlantic Rain forest and Savannah biomes, intensively used in the cosmetic industry. Nonetheless, to date, research has not addressed the management of natural stands or plantations of the species. Our experiment was located in Baependi, Minas Gerais, Brazil, and comprised of four randomized blocks and 13 treatments. The treatments consisted of 12 different regimes of fertilization plus a control. Each sample plot was composed of 50 plants plus two border plants in a planting spacing of 2.5 9 2.0 m and undergoing pruning at 5 and 6 years of age. Starting in the second year, total tree height（H） and circumference（at 1.30 m from the ground or breast height, CBH） were measured every 6 months. Starting in the fifth year CA was measured. Tree growth varied by fertilization *** were detected by using an autoregressive approach, considering that standard statistical methods were not powerful enough to detect significant *** growth groups were formed, and maximum growth was obtained for treatment 10（NPK, 8-28-16）. Management guidelines are provided based on individual tree models for different fertilization levels.

关键词： Management strategies Candeia Fertilization level Brazil Crown area

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Chemical Constituents from Caesalpinia férrea:Identification and ^(1)H and ^(13)C Resonance Assignment

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American Journal of Analytical Chemistry 2014年第10期5卷 688-694页

作者： Islay lima Magalhaes francisco Chagas lima Pinto Raimundo Braz Filho Daniele Alves Ferreira Telma Leda Gomes de Lemos francisco José Queiroz Monte Departamento de Química Organica e Inorganica Universidade Federal do CearáFortalezaBrasil Laboratório de Ciencias Químicas Centro de Ciencias TecnológicasUniversidade Estadual do Norte FluminenseCampos dos GoytacazesBrasil

In a phytochemical investigation of Caesalpinia ferrea (Leguminosae), four aromatic compounds (1-4) have been isolated and identified. Their structures have been assigned based on data provided by spectroscopic techni... 详细信息

关键词： Caesalpinia ferrea Leguminosae Aromatic Compounds Spectral Studies

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Monthly and seasonal streamflow forecasting of large dryland catchments in Brazil

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Journal of Arid Land 2021年第3期13卷 205-223页

作者： Alexandre C COSTA Alvson B S ESTACIO francisco de A de SOUZA FILHO Iran E lima NETO Institute of Engineering and Sustainable Development University of International Integration of the Afro-Brazilian LusophonyRedençãoCEP 62.790-970Brazil Department of Hydraulic Engineering and Environment Federal University of CearáFortalezaCEP 60.451-970Brazil

Streamflow forecasting in drylands is *** are scarce,catchments are highly humanmodified and streamflow exhibits strong nonlinear responses to *** goal of this study was to evaluate the monthly and seasonal streamflow forecasting in two large catchments in the Jaguaribe River Basin in the Brazilian semi-arid *** adopted four different lead times:one month ahead for monthly scale and two,three and four months ahead for seasonal *** gaps of the historic streamflow series were filled up by using rainfall-runoff ***,time series model techniques were applied,i.e.,the locally constant,the locally averaged,the k-nearest-neighbours algorithm(k-NN)and the autoregressive(AR)*** criterion of reliability of the validation results is that the forecast is more skillful than streamflow *** approach outperformed the streamflow climatology for all monthly *** average,the former was 25%better than the *** seasonal streamflow forecasting(SSF)was also reliable(on average,20%better than the climatology),failing slightly only for the high flow season of one catchment(6%worse than the climatology).Considering an uncertainty envelope(probabilistic forecasting),which was considerably narrower than the data standard deviation,the streamflow forecasting performance increased by about 50%at both *** forecast errors were mainly driven by the streamflow intra-seasonality at monthly scale,while they were by the forecast lead time at seasonal *** best-fit and worst-fit time series model were the k-NN approach and the AR model,*** rainfall-runoff modelling outputs played an important role in improving streamflow forecasting for one streamgauge that showed 35%of data *** developed data-driven approach is mathematical and computationally very simple,demands few resources to accomplish its operational implementation and is applicable to other dryland *** findings may be part of drou

关键词： nonlinear time series analysis probabilistic streamflow forecasting reconstructed streamflow data dryland hydrology rainfall-runoff modelling stochastic dynamical systems

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19-year remotely sensed data in the forecast of spectral models of the environment

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International Journal of Digital Earth 2021年第8期14卷 1040-1066页

作者： Fernando Saragosa Rossi Carlos Antonio da Silva Junior Joséfrancisco de Oliveira-Júnior Paulo Eduardo Teodoro Luciano Shozo Shiratsuchi Mendelson lima Larissa Pereira Ribeiro Teodoro Auana Vicente Tiago Guilherme Fernando Capristo-Silva State University of Mato Grosso(UNEMAT) Alta FlorestaMato GrossoBrazil Department of Geography State University of Mato Grosso(UNEMAT)SinopMato GrossoBrazil cFederal University of Alagoas(UFAL) MaceióAlagoasBrazil dFederal University of Mato Grosso do Sul(UFMS) Chapadão do SulMato Grosso do SulBrazil eAgCenter School of PlantEnvironmentaland Soil SciencesLouisiana State University(LSU)Baton RougeLouisianaUSA fPostgraduate Program in Agronomy Federal University of Mato Grosso(UFMT)SinopMato GrossoBrazil

The aims of this study were:i)to compare no-till areas in two municipalities located in different regions of Brazil,along with the influence on CO_(2)Flux and GPP,and ii)to verify the difference between environmental factors followed by the trends of these variables regarding future scenarios(ARIMA time-series model number).The study was carried out in two areas with different latitudes in the municipalities of Sinop-MT and Passo Fundo-RS,both in Brazil.A time series of 19 years was performed with data acquired by remote sensing from the following satellites:i)Landsat-8(OLI and TIRS),and ii)TERRA/AQUA(MODIS).The results propound that the spectro-temporal variables are directly influenced by soil management and agricultural practices over the observation time,with a satisfactory correlation in future predictions of the variables for the next ten years,in which presented that the variation of GPP and albedo values for the two study sites would gradually increase until 2028 and the temperature remained constant between the range of its seasonality,and CO_(2)Flux tends to decrease in its seasonality,indicating a higher CO_(2) absorption.

关键词： ARIMA numerical modeling remote sensing orbital products tillage

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