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Rising utilization of stable isotopes in tree rings for climate change and forest ecology

Journal of Forestry Research 2024年第1期35卷 103-116页

作者： Ru Huang Chenxi Xu Jussi Grießinger Xiaoyu Feng Haifeng Zhu achim Bräuning National Institute of Natural Hazards Beijing 100085People’s Republic of China Key Laboratory of Cenozoic Geology and Environment Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029People’s Republic of China CAS Center for Excellence in Life and Paleoenvironment Beijing 100044People’s Republic of China Institute of Geography Friedrich-Alexander-University of Erlangen-Nuremberg91058 ErlangenGermany State Key Laboratory of Tibetan Plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China

Analyses of stable isotopes(C,O,H)in tree rings are increasingly important cross-disciplinary *** rapid development in this field documented in an increasing number of publications requires a comprehensive *** study includes a bibliometric analysis-based review to better understand research trends in tree ring stable isotope ***,1475 publications were selected from the Web of Science Core Collection for *** findings are that:(1)numbers of annual publications and citations increased since *** 1974 to 1980,there were around two relevant publications per ***,from 2020 to 2022,this rose sharply to 109 publications per ***,average article citations were less than four per year before 1990,but were around four per article per year after 2000;(2)the major subjects using tree ring stable isotopes include forestry,geosciences,and environmental sciences,contributing to 42.5%of the total during 1974-2023;(3)the top three most productive institutions are the Chinese Academy of Sciences(423),the Swiss Federal Institute for Forest,Snow and Landscape Research(227),and the University of Arizona(204).These achievements result from strong collaborations;(4)review papers,for example,(Dawson et al.,Annu Rev Ecol Syst 33:507-559,2002)and(McCarroll and Loader,Quat Sci Rev 23:771-801,2004),are among the most cited,with more than 1000 citations;(5)tree ring stable isotope studies mainly focus on climatology and ecology,with atmospheric CO_(2) one of the most popular *** 2010,precipitation and drought have received increasing *** on this analysis,the research stages,key findings,debated issues,limitations and direc-tions for future research are *** study serves as an important attempt to understand the progress on the use of stable isotopes in tree rings,providing scientific guid-ance for young researchers in this field.

关键词： Tree rings Stable isotopes Web of Science Bibliometric

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开颅手术中动脉CO2分压和七氟烷对毛细血管静脉脑血流和氧饱和度的影响

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麻醉与镇痛 2011年第6期7卷 50-55页

作者： Departments of Klaus Ulrich Klein, MD Martin Glaser, MD Robert Reisch, MD, PhD achim tresch, msc Christian Werner, MD, PhD Kristin EngeLhard, MD, PhD 刘鲲鹏（译）李成辉（校） Departments of AnesthesiologyLudwig-Maximilians-University Munich Germany Departments ofNeurosurgery Johannes Gutenberg-University MainzGermanyLudwig-Maximilians-University Munich Germany Departmentof Chemistry and Biochemistry Gene Center MunichLudwig-Maximilians-University Munich Germany 不详

背景手术中常规监测脑血流和氧饱和度是一项技术上的挑战。基于脑血管对CO，反应性的生理学原理．我们对新近开发的一种神经监测仪（oxygen—to—see，O2CTM）在开颅手术患者同步监测毛细血管静脉局部脑血流量（rvCBF）、血流速度（rvV... 详细信息

背景手术中常规监测脑血流和氧饱和度是一项技术上的挑战。基于脑血管对CO，反应性的生理学原理．我们对新近开发的一种神经监测仪（oxygen—to—see，O2CTM）在开颅手术患者同步监测毛细血管静脉局部脑血流量（rvCBF）、血流速度（rvVelo）、氧饱和度（srvO2）和血红蛋白计数（rvHb）方面的表现进行评估。方法26例实施神经外科手术的患者，随机分g4采用呼气术浓度为1．4％和2．O％七氟烷进行麻醉。在颅骨切开后，在邻近手术部位肉眼所视正常的脑组织表面放置一光纤探头。每例患者同步监测较低动脉二氧化碳分压（PaCO2=35mmHg）和较高二氧化碳分压（PaC0，=45mmHg）时（随机排序）脑深度2mm和8mm处的组织脑血流。联合应用激光多普勒血流监测仪（rVcBF，rvVdo）和分光光度计（srvO，，rvHb）进行测量。采用线性模型检验较低和较高PaCO2、1.4％和2，0％呼气末七氟炕浓度2mm和8mm脑深度时rvCBF、rvVelo、srvO，和rvHb数值变化的线性关系。结果在脑组织深度2mm和8mm处，rvCBF和rvVelo随PaCO2升高而增加，与七氟皖浓度无关（P〈Q001）。高PaCO2使平均srvO2由50％升高至68％（P〈0．001）。与脑深度2mm处相比，脑深度8mm处的rvVelo（P〈0．001）和srvO，（P=0．007）较高。RvHb不受PaCO2变化的影响，但是与七氟垸浓度呈正相关（P=0．005）。结论PaCO：导致rvCBF和rvVelo增加，表明在呼气末七氟皖浓度1．4％和2％麻醉下，CO2增多可引起保护性血管扩张。SrvO2的连续升高表明PaCO2增高可导致脑动脉-静脉氧差缩小。RvHb不变表示测量期间未发生血液丢失。本研究显示，该神经监测仪可监测脑微血管主要静脉在不同PaCO2水平脑血流和氧饱和度的局部变化。

关键词：局部脑血流量 CO2分压氧饱和度毛细血管开颅手术七氟烷静脉动脉二氧化碳分压

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Development and characterization of 3D-printed electroconductive pHEMA-co-MAA NP-laden hydrogels for tissue engineering

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Bio-Design and Manufacturing 2024年第3期7卷 262-276页

作者： Sara De Nitto Aleksandra Serafin Alexandra Karadimou achim Schmalenberger John J.EMulvihill Maurice N.Collins DIBRIS Polytechnic Inter-School Section University of Genoa16126 GenoaItaly School of Engineering Bernal InstituteUniversity of LimerickLimerick V94 T9PXIreland School of Natural Sciences Department of Biological SciencesUniversity of LimerickLimerick V94 T9PXIreland Health Research Institute University of LimerickLimerick V94 T9PXIreland AMBER University of LimerickLimerick V94 T9PXIreland

Tissue engineering(TE)continues to be widely explored as a potential solution to meet critical clinical needs for diseased tissue replacement and tissue *** this study,we developed a poly(2-hydroxyethyl methacrylate-co-methacrylic acid)(pHEMA-co-MAA)based hydrogel loaded with newly synthesized conductive poly(3,4-ethylene-dioxythiophene)(PEDOT)and polypyrrole(PPy)nanoparticles(NPs),and subsequently processed these hydrogels into tissue engineered constructs via three-dimensional(3D)*** presence of the NPs was critical as they altered the rheological properties during ***,all samples exhibited suitable shear thinning properties,allowing for the development of an optimized processing window for 3D *** were 3D printed into pre-determined disk-shaped configurations of 2 and 10 mm in height and diameter,*** observed that the NPs disrupted the gel crosslinking efficiencies,leading to shorter degradation times and compressive mechanical properties ranging between 450 and 550 *** conductivity of the printed hydrogels increased along with the NP concentration to(5.10±0.37)×10^(−7)S/*** vitro studies with cortical astrocyte cell cultures demonstrated that exposure to the pHEMA-co-MAA NP hydrogels yielded high cellular viability and proliferation ***,hydrogel antimicrobial studies with staphylococcus epidermidis bacteria revealed that the developed hydrogels affected bacterial *** together,these materials show promise for various TE strategies.

关键词： Conductive nanoparticles Hydroxyethyl methacrylate(HEMA) Ultraviolet(UV)polymerization 3D printing

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追求卓越向“智”而行——访德国HAINBUCH瀚柏格夹具集团首席执行官achim Feinauer博士

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现代制造 2024年第S1期 24-26页

作者：张欣 achim Feinauer 不详德国HAINBUCH瀚柏格夹具集团

在高精度、高效率以及不断增长的柔性自动化需求的生产环境中,工件夹具的重要性日益凸显。随着行业转型升级步伐加快,多品种小批量生产乃至多品种大批量生产规模的需求快速增长,用户群体愈加重视夹具的选型和管理,这进一步对工装夹具提... 详细信息

在高精度、高效率以及不断增长的柔性自动化需求的生产环境中,工件夹具的重要性日益凸显。随着行业转型升级步伐加快,多品种小批量生产乃至多品种大批量生产规模的需求快速增长,用户群体愈加重视夹具的选型和管理,这进一步对工装夹具提出了更高的要求和挑战,带动了夹具的快速发展与创新。

关键词：多品种小批量生产柔性自动化工装夹具工件夹具大批量生产首席执行官追求卓越

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Anesthetic Management of a Patient with Spinal Muscular Atrophy Type III Undergoing Emergent Caesarean Section: A Case Report

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Open Journal of Anesthesiology 2024年第6期14卷 151-158页

作者： Kwame Awuku achim Younker Breta Osei-Bonsu Joseph Nalbone Aditi Master Dongchen Li Ming Xiong Rutgers New Jersey Medical School Newark New Jersey USA

In this case report, we describe the anesthetic management for a 36-year-old G2P0010 at 36 weeks gestation with Spinal Muscular Atrophy Type III who underwent an emergent caesarean section due to fetal footling breech position. The patient is a wheelchair-bound quadriplegic with kyphoscoliosis and a lack of cough reflex who required nasal continuous noninvasive ventilatory support (CNVS) for chronic hypercapnic respiratory failure. Surgery was done under general anesthesia due to its emergent nature, and the patient was successfully extubated and transitioned to nasal CNVS in the operating room at the end of the case. Postoperative care was provided in the medical intensive care unit for three days without complication and the patient was discharged home uneventfully.

关键词： Spinal Muscular Atrophy General Anesthesia Cesarean Section Obstetric Anesthesia

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Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed

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Infectious Diseases of Poverty 2024年第1期13卷 85-89页

作者： Robert Colebunders Joseph Nelson Siewe Fodjo Olivia Kamoen Luis-Jorge Amaral Amber Hadermann Chiara Trevisan Mark J.Taylor Julia Gauglitz achim Hoerauf Yasuaki Sato Katja Polman Maria-Gloria Basanez Dan Bhwana Thomson Lakwo Gasim Abd-Elfarag Sebastien D.Pion Global Health Institute University of AntwerpAntwerpBelgium Department of Neurology Heilig Hart ZiekenhuisLierBelgium Department of Public Health Institute of Tropical MedicineAntwerpBelgium Liverpool School of Tropical Medicine LiverpoolUK Department of Computer Science University of AntwerpAntwerpBelgium Institute of Medical Microbiology Immunology and ParasitologyUniversity Hospital BonnBonnGermany German Center for Infection Research(DZIF) Partner Site Bonn-CologneBonnGermany School of Global Humanities and Social Sciences Nagasaki UniversityNagasakiJapan MRC Centre for Global Infectious Disease Analysis and London Centre for Neglected TropicalDisease Research Department of Infectious Disease EpidemiologySchool of Public HealthImperial College LondonLondonUK National Institute for Medical Research TangaTanzania Vector Control Division Ministry of HealthKampalaUganda School of Public Health University of JubaJubaSouth Sudan Access for Humanity JubaSouth Sudan French National Research Institute for Sustainable Development MontpellierFrance

Background There is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing the concept of onchocerciasis-associated epilepsy (OAE). The aim of this paper is to provide an update on the new knowledge about OAE and to propose recommendations to the World Health Organization how to address this public health *** text During the 2nd International Workshop on OAE held on 19-21 September, 2023, in Antwerp, Belgium, participants recognised OAE as a substantial yet neglected public health problem, particularly in areas of sub-Saharan Africa where onchocerciasis remains hyperendemic. Evidence from prospective population-based studies suggest that strengthening onchocerciasis elimination efforts leads to a significant reduction of OAE incidence. There is a need to validate an OAE case definition to estimate the burden of disease and identify onchocerciasis-endemic areas requiring intensification of onchocerciasis elimination programmes and integration of epilepsy care. It is expected that raising awareness about OAE will boost the population uptake of ivermectin. The implementation of a community-based epilepsy treatment programme offering free anti-seizure medications (ASMs) has shown high effectiveness in reducing the frequency of seizures and improving the overall quality of life of people with *** To reduce OAE burden, enhanced collaboration between onchocerciasis and mental health programmes at community, national, and international levels is required. Urgent efforts are needed to ensure the uninterrupted provision of free ASMs in onchocerciasis-endemic areas. Furthermore, OAE should be included in the quantification of the onchocerciasis disease burden.

关键词： Onchocerciasis Morbidity Burden of disease Prevention Ivermectin Epilepsy Nodding syndrome Treatment Children Policy

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Combining High-Resolution Imaging,Deep Learning,and Dynamic Modeling to Separate Disease and Senescence in Wheat Canopies

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Plant Phenomics 2023年第2期5卷 295-312页

作者： Jonas Anderegg Radek Zenkl achim Walter Andreas Hund Plant Pathology Group Institute of Integrative BiologyETH ZurichZurichSwitzerland Crop Science Group Institute of Agricultural SciencesETH ZurichZurichSwitzerland

Maintenance of sufficiently healthy green leaf area after anthesis is key to ensuring an adequate assimilate supply for grain *** regulated age-related physiological senescence and various biotic and abiotic stressors drive overall greenness decay dynamics under field *** direct effects on green leaf area in terms of leaf damage,stressors often anticipate or accelerate physiological senescence,which may multiply their negative impact on grain ***,we present an image processing methodology that enables the monitoring of chlorosis and necrosis separately for ears and shoots(stems+leaves)based on deep learning models for semantic segmentation and color properties of vegetation.A vegetation segmentation model was trained using semisynthetic training data generated using image composition and generative adversarial neural networks,which greatly reduced the risk of annotation uncertainties and annotation *** of the models to image time series revealed temporal patterns of greenness decay as well as the relative contributions of chlorosis and ***-based estimation of greenness decay dynamics was highly correlated with scoring-based estimations(r≈0.9).Contrasting patterns were observed for plots with different levels of foliar diseases,particularly septoria tritici *** results suggest that tracking the chlorotic and necrotic fractions separately may enable(a)a separate quantification of the contribution of biotic stress and physiological senescence on overall green leaf area dynamics and(b)investigation of interactions between biotic stress and physiological *** high-throughput nature of our methodology paves the way to conducting genetic studies of disease resistance and tolerance.

关键词： Wheat enable image

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A high-order full-discretization method using Hermite interpolation for periodic time-delayed differential equations

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Acta Mechanica Sinica 2015年第3期31卷 406-415页

作者： Yilong Liu achim Fischer Peter Eberhard Baohai Wu Key Laboratory of Contemporary Design and Integrated Manufacturing Technology Northwestern Polytechnical University Institute of Engineering and Computational Mechanics University of Stuttgart

A high-order full-discretization method （FDM） using Hermite interpolation （HFDM） is proposed and implemented for periodic systems with time delay. Both Lagrange interpolation and Hermite interpolation are used to approximate state values and delayed state values in each discretization step. The transition matrix over a single period is determined and used for stability analysis. The proposed method increases the approximation order of the semidiscretization method and the FDM without increasing the computational time. The convergence, precision, and efficiency of the proposed method are investigated using several Mathieu equations and a complex turning model as examples. Comparison shows that the proposed HFDM converges faster and uses less computational time than existing methods.

关键词： Full-discretization method Time delay -Stability Chatter

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Unmasking lower gastrointestinal bleeding under administration of norepinephrine

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World Journal of Radiology 2022年第12期14卷 375-383页

作者： David John Werner Nicolai Wenzel Nael Abusalim Ralf Kiesslich Till Baar achim tresch Johannes Wilhelm Rey Department of Radiology Helios Dr.Horst-Schmidt-ClinicWiesbaden 65199HessenGermany Radiologie Rhein-Nahe Krankenhaus St.MarienwörthBad Kreuznach 55543Rheinland-PfalzGermany Department of Diagnostic and Interventional Radiology Medical Center HanauHanau 63450HessenGermany Department of Internal Medicine II Helios Dr.Horst-Schmidt-ClinicWiesbaden 65199HessenGermany Institute for Medical Statistics and Computational Biology Faculty of MedicineUniversity of CologneCologne 50923Nordrhein-WestfalenGermany Department of Gastroenterology and Endoscopy Medical Center OsnabrueckOsnabrueck 49076NiedersachsenGermany

BACKGROUND Bleeding in the gastrointestinal tract is common and transarterial embolization enables the clinician to control gastrointestinal *** extravasation is a prerequisite for successful *** angiography is helpful in the detection of elusive *** We performed a retrospective analysis of angiographic treatment in patients with lower gastrointestinal hemorrhage and initially negative angiographies,as well as the role of norepinephrine(NE)in unmasking *** We analyzed 41 patients with lower gastrointestinal bleeding after angiography who had undergone treatment over a period of 10 *** patients had a positive shock index and needed intensive *** In three of four patients,angiography disclosed the site of bleeding when NE was used during the procedure for hemodynamic *** We suggest that angiography performed after the administration of NE in unstable patients with gastrointestinal bleeding and an initially negative angiography has the potential to unmask bleeding sites for successful ***,this statement must be confirmed in prospective studies.

关键词： Lower gastrointestinal bleeding Endoscopy Provocative angiography Norepinephrine Radiology Gastrointestinal bleeding

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Stability analysis of a thin-walled cylinder in turning operation using the semi-discretization method

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Acta Mechanica Sinica 2014年第2期30卷 214-222页

作者： Arnab Chanda achim Fischer Peter Eberhard Santosha Kumar Dwivedy Institute of Engineering and Computational Mechanics University of Stuttgart

In this work, the stability of a flexible thin cylindrical workpiece in turning is analyzed. A process model is derived based on a finite element representation of the workpiece flexibility and a nonlinear cutting force law. Repeated cutting of the same surface due to overlapping cuts is modeled with the help of a time delay. The stability of the so obtained system of periodic delay differential equations is then determined using an approximation as a time-discrete system and Floquet theory. The time-discrete system is obtained using the semi-discretization method. The method is implemented to analyze the stability of two different workpiece models of different thicknesses for different tool positions with respect to the jaw end. It is shown that the stability chart depends on the tool position as well as on the thickness.

关键词： Machine tools Stability Chatter

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