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Liver cell cancer surveillance practice in Nigeria:Pitfalls and future prospects

World Journal of Hepatology 2024年第10期16卷 1132-1141页

作者： Yusuf Musa Ijeoma M Ifeorah abubakar sadiq maiyaki Rahama Mohammad Almustapha Yussuf Abdulkadir Maisuna Habib Tijjani Saleh Abdulmumini Yakubu Division of Gastroenterology and Hepatology Department of Internal MedicineFederal Teaching Hospital KatsinaKatsina 820101Nigeria Department of Medical Laboratory Sciences College of Medicine University of Nigeria Enugu CampusEnugu 400102Nigeria Division of Gastroenterology and Hepatology Department of Internal MedicineFaculty of Clinical SciencesCollege of Health SciencesUsmanu Danfodiyo UniversitySokoto 840283Nigeria Division of Gastroenterology and Hepatology Department of Internal MedicineUsmanu Danfodiyo University Teaching Hospital SokotoSokoto 840101Nigeria Infection Prevention and Control Unit Department of Community MedicineFederal Teaching HospitalKatsina 820101KatsinaNigeria Division of Gastroenterology and Hepatology Department of Internal MedicineBayero University KanoKano 700101Nigeria Division of Gastroenterology and Hepatology Department of Internal MedicineAminu Kano Teaching HospitalKano 700101Nigeria Division of Gastroenterology and Hepatology Department of Internal MedicineUsmanu Danfodiyo UniversitySokoto 840283Nigeria Division of Gastroenterology and Hepatology Department of Internal MedicineUsmanu Danfodiyo University Teaching HospitalSokoto 840283Nigeria

Hepatocellular carcinoma(HCC)is a disease of public health concern in Nigeria,with chronic hepatitis B and C infections contributing most to the disease *** the increasing incidence of HCC,surveillance practices for early diagnosis and possible cure are not deeply rooted in the *** article aims to review the current status of HCC surveillance in Nigeria,stressing the encounters,breaches,and potential *** factors,such as limited tools for screening and diagnostics,insufficient infrastructure,and low cognizance among the doctors,and the general public affect the surveillance practices for HCC in ***,the lack of standardized guidelines and protocols for HCC surveillance further intensifies the suboptimal diagnosis and ***,there are opportunities for refining surveillance practices in the *** would be achieved through boosted public health sensitization campaigns,integrating HCC screening into routine clinical services,and leveraging technological developments for early detection and ***,collaboration between government agencies,healthcare providers,and international organizations can facilitate the development of comprehensive HCC surveillance programs person-alized to the Nigerian ***,HCC surveillance practice faces substantial *** addressing the drawbacks and leveraging prospects,Nigeria can improve HCC surveillance,with subsequent improved outcomes for individuals at risk of developing the disease.

关键词： Hepatocellular cancer Surveillance Alpha-fetoprotein Ultrasonography Des-gamma-carboxy prothrombin Early disease Intermediate disease Late disease Advance disease

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DFT Study of Catalytic Dehydrogenation of Toluene on Different Platinum Surfaces

DFT Study of Catalytic Dehydrogenation of Toluene on Differe...

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作者： abubakar sadiq ABDULLAHI 厦门大学

学位级别：硕士

本文旨在利用密度泛函理论研究甲苯在铂(Pt)表面的催化氧化。首先,用热力学方法研究了甲苯在Pt(111)、(100)、(110)、(211)和(200)表面的化学吸附。结算结果表明,苯环与Pt表面具有较强的相互作用,导致甲苯分子变形;甲苯在Pt(111)和(100... 详细信息

本文旨在利用密度泛函理论研究甲苯在铂(Pt)表面的催化氧化。首先,用热力学方法研究了甲苯在Pt(111)、(100)、(110)、(211)和(200)表面的化学吸附。结算结果表明,苯环与Pt表面具有较强的相互作用,导致甲苯分子变形;甲苯在Pt(111)和(100)表面有稳定的吸附。在此基础上,本文进一步研究了甲苯在Pt(111)表面的分解过程,即通过过渡态搜索,计算了从甲苯的甲基和苯环中脱氢的活化能。计算结果表明,甲基中的C-H键较苯环上的C-H键弱。甲苯上甲基的脱氢反应(C6H5CH3→C6H5CH2→C6H5CH→C6H5C)是具有较低活化能的放热反应。与之相反,苯环的脱氢反应是吸热反应,且活化能较高。较低的活化能有利于甲苯的甲基在Pt(111)表面脱氢,而苯环上的氢不易脱除。甲苯上各键键长的变化说明了 Pt不同表面催化活性的差异。

关键词：甲苯催化铂脱氢 DFT 氧化

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Gain-enhanced reconfigurable radiation array with mechanically driven system and directive elements

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Frontiers of Mechanical Engineering 2022年第4期17卷 111-127页

作者： abubakar M.sadiq Yuanqing GU Yu LUO Yan CHEN Kaixue MA Tianjin Key Laboratory of Imaging and Sensing Microelectronic Technology School of MicroelectronicsTianjin UniversityTianjin 300072China School of Mechanical Engineering Tianjin UniversityTianjin 300072China

In the artificial intelligence-driven modern wireless communication system,antennas are required to be reconfigurable in terms of size according to changing application ***,conventional antennas with constant phase distributions cannot achieve enhanced gains in different reconfigurable *** this paper,we propose a mechanically reconfigurable radiation array(RRA)based on miniaturized elements and a mechanically reconfigurable system to obtain gain-enhanced antennas in compact and deployed states.A five-element RRA with a phase-reconfigurable center element is designed and analyzed *** experimental sample has been fabricated,driven by a deployable frame with only one degree of freedom to realize the size and phase distribution reconfiguration simultaneously to validate the enhanced gains of *** proposed RRA can be tessellated into larger arrays to achieve higher gains in other frequency regimes,such as terahertz or photonics applications with nanometer fabrication technology.

关键词： mechanism reconfigurable radiation array(RRA) compact state deployed state enhanced gain

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Growth and nitrogen productivity of drip-irrigated winter wheat under different nitrogen fertigation strategies in the North China Plain

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Journal of Integrative Agriculture 2023年第3期22卷 908-922页

作者： Sunusi Amin abubakar Abdoul Kader Mounkaila HAMANI WANG Guang-shuai LIU Hao Faisal MEHMOOD abubakar sadiq ABDULLAHI GAO Yang DUAN Ai-wang Key Laboratory of Crop Water Use and Regulation Ministry of Agriculture and Rural Affairs/Farmland Irrigation Research InstituteChinese Academy of Agricultural SciencesXinxiang 453002P.R.China Graduate School of Chinese Academy of Agricultural Sciences Beijing 100081P.R.China Department of Agricultural and Bioresource Engineering Abubakar Tafawa Balewa UniversityBauchi 740272Nigeria

Excessive application of nitrogen (N) fertilizer is the main cause of N loss and poor use efficiency in winter wheat (Triticum aestivum L.) production in the North China Plain (NCP).Drip fertigation is considered to be an effective method for improving N use efficiency and reducing losses,while the performance of drip fertigation in winter wheat is limited by poor N scheduling.A two-year field experiment was conducted to evaluate the growth,development and yield of drip-fertigated winter wheat under different split urea (46%N,240 kg ha^(-1)) *** six treatments consisted of five fertigation N application scheduling programs and one slow-release fertilizer (SRF) *** five N scheduling treatments were N0–100 (0%at sowing and 100%at jointing/booting),N25–75 (25%at sowing and 75%at jointing and booting),N50–50(50%at sowing and 50%at jointing/booting),N75–25 (75%at sowing and 25 at jointing/booting),and N100–0 (100%at sowing and 0%at jointing/booting).The SRF (43%N,240 kg ha^(-1)) was only used as fertilizer at *** N application significantly (P<0.05) affected wheat grain yield,yield components,aboveground biomass (ABM),water use efficiency(WUE) and nitrogen partial factor productivity (NPFP).The N50–50 and SRF treatments respectively had the highest yield(8.84 and 8.85 t ha^(-1)),ABM (20.67 and 20.83 t ha^(-1)),WUE (2.28 and 2.17 kg m^(-3)) and NPFP (36.82 and 36.88 kg kg^(-1)).This work provided substantial evidence that urea-N applied in equal splits between basal and topdressing doses compete economically with the highly expensive SRF for fertilization of winter wheat *** the single-dose SRF could reduce labor costs involved with the traditional method of manual spreading,the drip fertigation system used in this study with the N50–50 treatment provides an option for farmers to maintain wheat production in the NCP.

关键词： split nitrogen strategies wheat yield drip fertigation water use efficiency nitrogen use efficiency

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Interplay of transport vesicles during plant-fungal pathogen interaction

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Stress Biology 2023年第1期3卷 377-386页

作者： Yakubu Saddeeq abubakar Idris Zubair sadiq Aarti Aarti Zonghua Wang Wenhui Zheng State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops College of Life SciencesFujian Agriculture and Forestry UniversityFuzhouChina Key Laboratory of Integrated Pest Management for Fujian-Taiwan Crops Ministry of AgricultureCollege of Plant ProtectionFujian Agriculture and Forestry UniversityFuzhouChina Department of Biochemistry Faculty of Life SciencesAhmadu Bello UniversityZariaNigeria Fuzhou Institute of Oceanography Minjiang UniversityFuzhouChina

Vesicle trafficking is an essential cellular process upon which many physiological processes of eukaryotic cells *** is usually the‘language’of communication among the components of the endomembrane system within a cell,between cells and between a cell and its external ***,cells have the potential to internalize membrane-bound vesicles from external sources by *** constantly interact with both mutualistic and pathogenic microbes.A large part of this interaction involves the exchange of transport vesicles between the plant cells and the ***,in a pathogenic interaction,the pathogen releases vesicles containing bioactive molecules that can modulate the host immunity when absorbed by the host *** response to this attack,the host cells similarly mobilize some vesicles containing pathogenesis-related compounds to the pathogen infection site to destroy the pathogen,prevent it from penetrating the host cell or annul its *** fact,vesicle trafficking is involved in nearly all the strategies of phytopathogen attack subsequent plant immune ***,this field of plant-pathogen interaction is still at its infancy when narrowed down to plant-fungal pathogen interaction in relation to exchange of transport ***,we summarized some recent and novel findings unveiling the involvement of transport vesicles as a crosstalk in plant-fungal phytopathogen interaction,discussed their significance and identified some knowledge gaps to direct future research in the *** roles of vesicles trafficking in the development of both organisms are also established.

关键词： Endosomes Extracellular vesicles Plant-pathogen interaction Phytopathogens Vesicles trafficking

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Low-Lying Isomers of(TiO_(2))_(n)(n=2-8)Clusters

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Chinese Journal of Chemical Physics 2022年第2期35卷 311-321,I0002页

作者： Binli Wang abubakar sadiq Abdullahi Yahui Wang Hong-Jun Fan State Key Laboratory of Molecular Reaction Dynamics Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China University of Chinese Academy of Sciences Beijing 100049China

Although there are diverse bond features of Ti and O atoms,so far only several isomers have been reported for each(TiO_(2))n *** of the widely used global optimization,in this work,we search for the low-lying isomers of(TiO_(2))_(n)(n=2-8)clusters with up to 10000 random sampling initial *** structures were optimized by the PM6 method,followed by density functional theory *** this strategy,we have located many more low-lying isomers than thosereported *** number of isomers increases dramatically with the size of the cluster,and about 50 isomers were found for(TiO_(2))_(7) and(TiO_(2))_(8) with the energy within 30 kcal/***,new lowest isomers have been located for(TiO_(2))_(5) and(TiO_(2))_(8),and isomers with three terminal oxygen atoms,five coordinated oxygen atoms as well as six coordinated titanium atoms have been *** work highlights the diverse structural features and a large number of isomers of small TiO_(2) clusters.

关键词： TiO_(2) Cluster Low-lying isomer Density functional theory Geometric structure

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Spectrum of Bladder Cancer Patients Morbidity and Mortality in a Tertiary Hospital of Northwestern Nigeria: A 7-Year Review

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Open Journal of Urology 2021年第2期11卷 36-44页

作者： abubakar sadiq Muhammad Abdullahi Khalid Urology Unit Department of Surgery Usmanu Danfodiyo University Teaching Hospital Sokoto Nigeria

Background: Bladder cancer is a common cause of morbidity and mortality in our institution due to the late presentation. Morbidity is defined as a development of complications that may lead to mortality. Uraemia is a common presentation that constitutes a management challenge in our patients. We study the spectrum of morbidity and mortality in bladder cancer patients in our institution. Materials and Methods: This is a retrospective study of patients with clinical, radiological, cytological and or histological features of bladder cancer that had a morbidity and or mortality managed at Usmanu Danfodiyo University Teaching Hospital Sokoto from January 2011 to December, 2017. Data were retrieved from patients’ case notes via a proforma and analyzed using SPSS 20.0 version for windows. The results were presented in number percent, tables and chart. Results: There were morbidity and or mortality in 234 bladder cancer patients within the study period with a mean age of 48.4 ± 14.1 years and a range of 3 - 106 years. There were 219 males (91.5%) and 20 females (8.5%) with a male to female ratio of 11:1. There were haematuria and lower urinary tract symptoms (LUTS) in 230 patients (98.3%). There were necroturia ± weight loss and anorexia in 126 patients (53.8%). There was urinary tract infection (UTI) in 75 patients (32.1%), anaemia in 131 patients (56.0%) and uraemia in 161 patients (68.8%). Mortality was recorded in 84 patients (35.9%) which was due to uraemia in 52 patients (22.2%), urosepsis in 22 patients (9.4%) and anaemia in 8 patients (3.4%), intestinal obstruction and blood transfusion reaction in 1 patient each (0.4%). Conclusion: Anaemia, urosepsis and uraemia are the most common causes of morbidity and or mortality in bladder tumour patients in Sokoto. This poses great diagnostic and therapeutic dilemma to the urologist, patients and their relatives.

关键词： Bladder Cancer Morbidity Mortality Urosepsis Uraemia Anaemia

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The Occurence of Gastrointestinal Helminths in Slaughtered Cattle in Azare, North-East Nigeria

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Journal of Zoological Research 2021年第1期3卷 1-8页

作者： Musa Umar Bashir Mohammed abubakar Haladu Ali Gagman abubakar sadiq Yusuf Department of Biological Sciences Bauchi State University GadauPMB 065BauchiNigeria

A Cross-sectional Study was carried out to determine the prevalence of gastrointestinal(G.I.)helminths parasites in slaughtered cattle at Azare abattoir,Katagum Local Government Area,Bauchi State,North-Eastern *** hundred and twenty faecal samples were examined using the floatation and sedimentation *** of the total samples tested,*** infections were detected in 62 samples tested,giving an overall prevalence of 51.6%.Class nematodes are the most diverse class(56.5%),followed by trematodes(35.5%),while cestodes are the least prevalent(8.1%).There was a statistically significant difference in ***’prevalence among different classes(p0.05).The Red Bororo breeds had the highest prevalence of 75%,while the least was recorded in White Fulani and Sokoto Gudali,40%*** was a statistically significant difference in G.I helminth infection’s prevalence rate to breed(p<0.05).This study revealed that Fasciola spp.(15%)is the most prevalent *** parasites detected,followed by Oesophagostomum spp(11.7%);Haemonchus spp.(9.2%);Strongyloides spp.(8.3%),Schistosoma spp.(3.3%);and Moniezia spp.(1.67%).Our findings from the present study revealed a high prevalence of *** species affecting cattle in Azare,North-East ***,there is a great need for proper advocacy on appropriate management,regular deworming practices,and improved cattle hygiene to boost animal *** will help in curbing significant loss to Nigeria’s economy and the world in general.

关键词： Gastrointestinal helminths Parasites Cattle Bauchi Nigeria

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Geology of the Structurally Controlled Quartz Vein Gold Mineralization in the Dikko Area, Part of Zungeru—Minna—Birnin Gwari Schist Belt, NW Nigeria

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Journal of Geoscience and Environment Protection 2021年第7期9卷 180-191页

作者： Abdullahi Adamu Mohammed Adamu Usman Mohammed Otorison Abdulganiu Danladi abubakar sadiq Applied Geology Department Abubakar Tafawa Balewa University Bauchi Nigeria Geology Department (Engineering Services) Federal Capital Development Authority (FCDA) Abuja Nigeria Hadejia Jama’are River Basin Development Authority Kano Nigeria

Dikko area, Niger State, North Central Nigeria falls within the Pan-African thermo-tectonic event which occurred in Nigeria as in other parts of West Africa with widespread effect on the mineralization of rejuvenated basement and geosynclinal trough deposits. The Pan-African Belt in Nigeria forms part of the Benin-Nigeria (Dahomeyan) shield which is regarded as the southern prolongation of the circumcratonic Pan-African belt of the West African Craton. Structurally controlled, gold-bearing quartz veins were measured and studied in the area from an extensive geological ground investigation. Field and petrographical studies indicate that the Neoproterozoic rocks constitute gneisses, amphibolite schist, amphibolites and migmatites. The amphibolites are intruded by pegmatites. The associated quartz veins are generally concordant with the main N-S regional structural trend. The lithological and structural studies carried out in these areas have demonstrated the relationship between structures and mineralization and/or lithology. The main characteristics of the gold mineralization in the area appear to indicate hydrothermal mineralization in connection with shear zones. This study allows us to predict that quartz veins in the amphibolite can be mined at a profit and a detailed geochemical and resource valuation needs to be carried out for the Au and associated Galena and Ag mineralization to fully exploit their economic potential.

关键词： Gold Mineralization Quartz Veins Pan-African Economic Potential Mined

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Phallic rubber band application to prevent enuresis unusual cause of urethral stricture in a child:A case report

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World Journal of Clinical Urology 2023年第2期12卷 10-16页

作者： Abdullahi Khalid Musa Nasiru Abdullahi Abdulwahab-Ahmed abubakar sadiq Muhammad Ngwobia Peter Agwu Christopher Suiye Lukong 不详

BACKGROUND Urethral stricture is the abnormal narrowing of the urethra due to *** established aetiological factors for urethral stricture abound in our ***,the application of a penile rubber band to prevent enuresis thereby causing this pathology is not a familiar *** with enuresis can suffer psycho-social challenges and trauma,especially for a child due to peer *** has a great impact on the child's psyche and may affect even his performance at *** aim of this paper is to highlight the psychosocial impact and management challenges of a child with enuresis(nocturnal urinary incontinence).CASE SUMMARY This is the case of a 10-year-old boy who presented with a history of nocturnal urinary incontinence since birth and lower urinary tract symptoms(LUTS)for 3 years culminating in chronic urinary *** maintained a normal urge to micturate and continent of urine during the daytime before the onset of *** had an antecedent longstanding history of tying a rubber band to the penile shaft mostly before going to the bed at night to prevent enuresis due to his peer *** was acutely ill-looking,with distended suprapubic *** phallus and scrotum were enlarged and oedematous with a circumferential proximal penile shaft scar and ventral penile shaft urethrocutaneous *** was diagnosed to have complete short segment bulbopenile stricture and right ectopic *** subsequent had augmented anastomotic urethroplasty and bilateral non-refluxing ureteroneocystostomy at different *** The adherence to surgical principles of urethral stricture and enuresis management where surgically correctable in a child is associated with the resolution of enuresis and social reintegration.

关键词： Enuresis Double ureter Ectopic ureter Rubber band Urethral stricture Case report

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