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Journal of Pharmaceutical Analysis 2024年第4期14卷 615-618页

作者： yue Liu Mengjia Li Xing Fu yi Zhang Ce tang state Key Laboratory of southwestern Chinese Medicine Resources School of Ethnic MedicineChengdu University of Traditional Chinese MedicineChengdu611137China Meishan Hospital of Chengdu University of Traditional Chinese Medicine MeishanSichuan620010China Innovative Institute of Chinese Medicine and Pharmacy Chengdu University of Traditional Chinese MedicineChengdu611137China

The dried roots of Aconitum pendulum Busch are the major source of a commonly used Tibetan medicine,namely Tiebangchui(TBC)(Fig.s1).However,raw TBC contains a large amount of high toxic diester-diterpenoid alkaloids(DDAs),and the improper use would cause arrhythmia,irreversible cardiovascular damages,and even death.“Paozhi”,an appropriate processing method,is the essential prerequisite for the safe clinical application of ***-decocting and sand-frying are commonly used processing methods for toxicity attenuation and efficacy preservation for TBC.

关键词： dried irreversible roots

Arbuscular mycorrhizae status of host plant affects offspring's phenotype and transcriptome expression in a low-phosphorus environment

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JOURNAL OF PLANT ECOLOGy 2024年第2期17卷 173-187页

作者： Liu, shijun Xu, Jing Huang, Hong tang, Jianjun Chen, Xin Liaoning Normal Univ Sch Life Sci Key Lab Plant Biotechnol Liaoning Prov Dalian 116081 Peoples R China Zhejiang Univ Coll Life Sci Hangzhou 310058 Peoples R China Zhejiang Acad Agr sci Inst Environm Resources & Soil Fertilizers Hangzhou 310021 Peoples R China

Although the effects of arbuscular mycorrhizal fungi (AMF) on host plants have been well documented, whether the effects of AMF on parental generations affect offspring performance is not fully clear. We conducted a common garden experiment to determine whether AMF status of host plants (Medicago truncatula) affects phenotype and transcriptome expression of their offspring. seeds from four type parental treatments (low-phosphorus (P) soil without AMF, low-P soil with AMF, high-P soil without AMF and high-P soil with AMF) were grown under low-P (LPs) and normal-P soil (OHs) conditions. The flowering pattern of LP offspring was similar to their parents, such that plants with AMF flowered earlier than those without AMF under OHs condition but were opposite under LPs condition. The transcriptome differential analysis showed that some differential transcripts (45 for parental plants growing under low-P condition and 3 for parental plants growing under high-P condition) expression patterns between offspring were comparable, and that only affected by parental AMF status regardless of the P environment that offspring was grown. Others (146 for parental plants growing under low-P condition and 2 for parental plants growing under high-P condition), however, were affected both by the parental AMF status and the offspring P environment. In addition, the number of differential transcripts between offspring whose parental plants grew under high-P condition was far less than under low-P condition. These results indicate that AMF may not only affect the current generation of host plants but also affect the offspring especially when their parents have experienced a stressful environment.

关键词： arbuscular mycorrhizal fungi low-phosphorus environment flowering pattern transgenerational effects transcriptome differential analysis PHOsPHATE DEFICIENCy ARABIDOPsIs ROOTs FUNGI COLONIZATION REsPONsEs sTREss INHERITANCE

Neiguan(PC6) acupoint stimulation for preventing chemotherapy-induced nausea and vomiting: a cost-effective supplement in guideline-inconsistent chemotherapy-induced nausea and vomiting prophylaxis subgroup

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Journal of Traditional Chinese Medicine 2024年第3期44卷 581-585页

作者： yU Wenxi tang Lina LI Hongtao WANG yonggang sHEN Zan Department of Oncology Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai200233China

OBJECTIVE: To assess the efficacy and safety of Neiguan(PC6) acupoint acustimulation in preventing chemotherapy-induced nausea and vomiting(CINV),especially for patients with guideline-inconsistent CINV prophylaxis(GICP) due to personal reasons METHODs: From January 2021 to December 2021, 373 patients suffered from solid malignancy were recruited according to the inclusion criteria. Complete response(no emesis and no rescue medication use) rate during the overall phase(0-120 h of each chemo-cycle) was the primary assessment of CINV control. The Functional Living Index-Emesis(FLIE) questionnaire was investigated among these patients as a secondary 'quality of life' objective to assess the impact of CINV on patients' daily life by recording score of nausea and vomiting. REsULTs: With acustimulation of Neiguan(PC6) acupuncture point through a portable, noninvasive and user-friendly device, in terms of complete response rate and scores in nausea/vomiting by FLIE questionnaire, patients achieve a better outcome in highly emetogenic chemotherapy(HEC) induced CINV, especially GICP subgroup. Meanwhile, analysis also demonstrated this tendency existed in other patients with HEC/GCCP(guideline consistent CINV prophylaxis) and moderate emetogenic chemotherapy, although the difference was not significant. CONCLUsION: Considering advantages of Neiguan(PC6) acustimulation such as noninvasive, covered by medical insurance and few side effects, we believe it would be an ideal auxiliary tool in CINV control, especially in patients who receive highly emetogenic chemoprotocol and are reluctant to GCCP for economic reasons.

关键词： acupuncture acustimulation tumor chemotherapy-induced nausea and vomiting

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Evaluating the relative importance of predictors in Generalized Additive Models using the *** R package

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Plant Diversity 2024年第4期46卷 542-546页

作者： Jiangshan Lai Jing tang Tingyuan Li Aiying Zhang Lingfeng Mao College of Ecology and Environment Nanjing Forestry UniversityNanjing210037China Research Center of Quantitative Ecology Nanjing Forestry UniversityNanjing 210037China University of Chinese Academy of sciences Beijing100049China Guangzhou Climate and Agro-meteorology Center Guangzhou 511430China Guangdong Ecological Meteorological Center Guangzhou 510640China

Generalized Additive Models(GAMs)are widely employed in ecological research,serving as a powerful tool for ecologists to explore complex nonlinear relationships between a response variable and ***,evaluating the relative importance of predictors with concurvity(analogous to collinearity)on response variables in GAMs remains a *** address this challenge,we developed an R package named *** calculates individual R^(2) values for predictors,based on the concept of'average shared variance',a method previously introduced for multiple regression and canonical *** these individual R^(2)s,which add up to the overall R^(2),researchers can evaluate the relative importance of each predictor within *** illustrate the utility of the *** package by evaluating the relative importance of emission sources and meteorological factors in explaining ozone concentration variability in air quality data from London,*** believe that the *** package will improve the interpretation of results obtained from GAMs.

关键词： Average shared variance Coefficient of determination Commonality analysis GAMs Hierarchical partitioning Individual R^(2)

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Lone-star retractor perineal exposure method for laparoscopic abdominal perineal resection of rectal cancer

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World Journal of Gastrointestinal surgery 2024年第8期16卷 2528-2537页

作者： Jun Ma Dai-Bin tang yu-Quan tang Da-Tian Wang Peng Jiang ya-Ming Zhang Department of General surgery Anqing Municipal HospitalAnqing 246000Anhui ProvinceChina Department of Anesthesiology Anqing Municipal HospitalAnqing 246000Anhui ProvinceChina

BACKGROUND The abdominal perineal resection(APR),historically referred to as Mile’s proce-dure,stands as a time-honored surgical intervention for rectal cancer *** in surgical techniques and the advent of neoadjuvant therapies have significantly improved the rate of sphincter preservation among patients afflicted with rectal cancer,including those with ultralow rectal *** these improvements,APR maintains its irreplaceable role in the clinical landscape,particularly for cases involving low rectal cancer with encroachment on the external anal sphincter or levator ani *** perineal exposure stands as a pivotal phase in APR,given that the precision of this maneuver is directly correlated with both the safety of the surgery and the patient’s subse-quent long-term *** To evaluate the value of Lone-star retractor(LsR)perineal exposure method in the treatment for laparoscopic APR of rectal *** We reviewed the records of 38 patients with rectal cancer at Anqing Municipal Hospital from January 2020 to December 2023,including 20 patients who underwent the APR procedure with a LsR perineal exposure method(LsR group)and 18 patients who underwent the APR procedure with a conventional perineal exposure method(control group).In the LsR group,following incision of the skin and subcutaneous tissue,the LsR was placed and dynamically adjusted according to the surgical plane to fully expose the perineal operative *** A total of 38 patients underwent laparoscopic APR,none of whom were found to have distant metastasis upon intraoperative *** blood loss,the postoperative hospital stays and the wound pain scores in the LsR group were significantly lower than those in the control group.A single surgeon completed the perineal operation significantly more often in the LsR group than in the control group(Psion in the LsR group was significantly lower

关键词： Rectal cancer Lone-star retractor Abdominal perineal resection Perineal exposure method Technique

Iridoschisis misdiagnosed as acute angle-closure glaucoma:a case report and literature review

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 201-205页

作者： Huan Wan yao Zhang Li tang Department of Ophthalmology West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Ophthalmology People’s Hospital of MeishanMeishan 620010Sichuan ProvinceChina

We present the case of a patient with iridoschisis complicated with cataract,peripheral anterior synechiae(PAs),secondary glaucoma,and corneal endothelial *** patient was initially misdiagnosed with acute angle-closure *** is a rare condition characterized by the splitting of the iris into two layers:the anterior layer breaks down into fibers,floating freely in the anterior chamber with a“shredded wheat”appearance.

关键词： glaucoma acute closure

soluble epoxide hydrolase:a next-generation drug target for Alzheimer's disease and related dementias

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Neural Regeneration Research 2025年第9期20卷 2585-2586页

作者： Andrew Gregory Chengyun tang Fan Fan Department of Physiology Medical College of GeorgiaAugusta UniversityAugustaGAUSA

Alzheimer's disease(AD)and Alzheimer's diseaserelated dementias(ADRD)represent a significant public health challenge,with projections indicating a substantial increase in affected individuals due to the aging global *** the World Health Organization,AD/ADRD has affected more than 55 million individuals worldwide,with an additional 10 million cases diagnosed each year.

关键词： Alzheimer population. drug

simulation study on Constraining Gravitational Wave Propagation speed by Gravitational Wave and Gamma-ray Burst Joint Observation on Binary Neutron star Mergers

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Research in Astronomy and Astrophysics 2024年第8期24卷 42-51页

作者： Jin-Hui Rao shu-Xu yi Lian Tao Qing-Wen tang Department of Physics School of Physics and Materials ScienceNanchang UniversityNanchang 330031China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

Theories of modified gravity suggest that the propagation speed of gravitational waves(GW)v_gmay deviate from the speed of light c.A constraint can be placed on the difference between c and v_gwith a simple method that uses the arrival time delay between GW and electromagnetic wave simultaneously emitted from a burst *** simulated the joint observation of GW and short gamma-ray burst signals from binary neutron star merger events in different observation campaigns,involving advanced LIGO(aLIGO)in design sensitivity and Einstein Telescope(ET)joint-detected with Fermi/*** a result,the relative precision of constraint on v_gcan reach~10~(-17)(aLIGO)and~10^(-18)(ET),which are one and two orders of magnitude better than that from GW170817,*** continue to obtain the bound of graviton mass m_g≤7.1(3.2)×10~(-20)eV with aLIGO(ET).Applying the standard-Model Extension test framework,the constraint on v_gallows us to study the Lorentz violation in the nondispersive,nonbirefringent limit of the gravitational *** obtain the constraints of the dimensionless isotropic coefficients s_(00)^(4)at mass dimension d=4,which are-1×10^(-15)s_(00)^(4)s_(00)^(4<8<10^(-18))for ET.

关键词： gravitational waves-(stars)gamma-ray burst general-stars neutron

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In situ-Constructed LixMos2 with Highly Exposed Interface Boosting High-Loading and Long-Life Cathode for All-solid-state Li-s Batteries

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Energy & Environmental Materials 2024年第4期7卷 163-174页

作者： Hao Li Rui Wang Jiangping song Dan Liu Hongyang Gao yimin Chao Haolin tang A state Key Laboratory of Advanced Technology for Materials synthesis and Processing Wuhan University of Technology Department of Chemistry Chemical Engineering and Life Science Wuhan University of Technology Foshan Xianhu Laboratory of the Advanced Energy science and Technology Guangdong Laboratory school of Chemistry University of East Anglia

As the persistent concerns regarding sluggish reaction kinetics and insufficient conductivities of sulfur cathodes in all-solid-state Li-s batteries(AssLsBs),numerous carbon additives and solid-state electrolytes (ssEs) have been incorporated into the cathode to facilitate ion/electron pathways around ***,this has resulted in a reduced capacity and decomposition of ssEs.

关键词： all-solid-state lithium–sulfur batteries conversion/intercalation high-loading and long-life low carbon content mixed ionic/electronic conductivities

Application of electromagnetic metallurgy in continuous casting: A review

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Progress in Natural science:Materials International 2024年第1期34卷 1-11页

作者： Jiale Li yi Nian Xiang Liu youcheng Zong Xinyu tang Chaojie Zhang Liqiang Zhang The Intelligent Metallurgy Research Institute School of Metallurgical Engineering Anhui University of Technology

The standards within the global steel industry are constantly advancing, necessitating increasingly rigorous quality control protocols during the continuous casting process. Central to the challenges faced in this domain are persistent defects such as central segregation, V-shaped segregation, and center porosity, which significantly impede the production of high-caliber steel products. The discipline of electromagnetic metallurgy has emerged as a critical solution in reducing these defects, thereby enhancing the efficiency and stability of continuous casting operations. Its demonstrated effectiveness has led to its widespread implementation across global and domestic steel production industries. This paper aims to deliver a comprehensive examination of electromagnetic metallurgy's impact on the final stages of solidification in continuous casting, along with its contributions to the heating and purification processes within the tundish. Additionally, it will explore the potential advancements and applications of this technology in the evolving sphere of continuous casting.

关键词： continuous casting Quality control Final electromagnetic stirring Induction heating Electromagnetic purification