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Prevalence and outcomes of polycystic kidney disease in African populations:A systematic review

World Journal of Nephrology 2024年第1期13卷 33-40页

作者： Modou Ndongo Lot Motoula Nehemie Baratou Coundoul abou abdallah malick diouara Sidy Mohamed Seck Department of Nephrology and Dialysis Regional Hospital of KedougouKedougou 26005Senegal Department of Nephrology and Dialysis Military Hospital of OuakamDakar 28216Senegal Department of Chemical Engineering and Applied Biology Polytechnic high School of Cheikh Anta Diop UniversityDakar 5085Senegal Department of Nephrology Faculty of Health SciencesUniversity Gaston BergerSaint-Louis 234Senegal

BACKGROUND Polycystic kidney disease(PKD)is the most common genetic cause of kidney *** is a progressive and irreversible condition that can lead to end-stage renal disease and many other visceral *** comprehensive data on PKD patterns in Africa is *** To describe the prevalence and outcomes of PKD in the African *** A literature search of PubMed,African journal online,and Google Scholar databases between 2000 and 2023 was *** Preferred Reporting Items for Systematic Reviews and Meta-Analyses were followed to design the *** presentations and outcomes of patients were extracted from the included *** Out of 106 articles,we included 13 studies from 7 African *** of them were retrospective descriptive studies concerning 943 PKD patients with a mean age of 47.9 *** accurate prevalence and incidence of PKD were not known but it represented the third causal nephropathy among dialysis *** majority of patients,the diagnosis of the disease was often *** function impairment,abdominal mass,and hypertension were the leading symptoms at presentation with a pooled prevalence of 72.1%(69.1-75.1),65.8%(62.2-69.4),and 57.4%(54.2-60.6)*** and infections were the most frequent *** was performed in few studies that revealed a high proportion of new mutations mainly in the PKD1 *** The prevalence of PKD in African populations is not clearly *** symptoms were almost present with most patients who had kidney function impairment and abdominal mass at the *** studies including genetic testing are needed to determine the burden of PKD in African populations.

关键词： Polycystic kidney disease Africa Genetic disorder Systematic review

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Control of Cardiovascular Risk Factors in the Semi-Urban Population of Guéoul in Senegal

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World Journal of Cardiovascular Diseases 2021年第1期11卷 69-81页

作者： Mame Madjiguène Ka Serigne Cheikh Tidiane Ndao Kana Sonia Babaka Abu Bakr Fafa Cissé abdallah Ould Béchir Isabelle Kouamé malick Ndiaye Dior Diagne Sow Moussa Kane Bouna Diack Alassane Mbaye Abdoul Kane Cardiology Unit of Grand Yoff General Hospital Dakar Senegal

Introduction: Cardiovascular disease is a global public health problem. In Africa, they are increasingly common, however, data on the control of cardiovascular risk factors in the general Senegalese population are rare. The aim of this work was to assess the level of control of cardiovascular risk factors in semi-urban areas in the municipality of Guéoul in Senegal. Patients and methods: This is a cross-sectional, descriptive and exhaustive survey carried out from 3 November to 3 December 2012 among the population aged at least 35 years and living for more than 6 months in the commune of Gueoul. It was conducted using the WHO STEPS approach to study the prevalence of cardiovascular risk factors and assess their level of control. We looked at clinical history, lifestyle, and anthropometric data. Blood pressure was measured at both arms and fasting blood samples were taken for blood glucose, cholesterol and triglycerides. Results: We examined 1.411 subjects (1052 women) averaging 48.5 ± 12.7 years of age. The main cardiovascular risk factors were dyslipidemia (61%), sedentary (56%), abdominal obesity (53.9%), high blood pressure (46.4%) and diabetes (7.2%). Dyslipidemia was known in 22 subjects, 6 of whom were on treatment with dyslipidemia control in 1 subject (16.7%). Hypertension was known in 266 subjects. Of these, 205 subjects were prescribed medical treatment, 26 of whom were well controlled (12.7%). The level of hypertension control was lower in subjects at high cardiovascular risk

关键词： Cardiovascular Risk Factors Control Hypertension Africa

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