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Gastrointestinal radiation injury:Prevention and treatment

World Journal of Gastroenterology 2013年第2期19卷 199-208页

作者： abobakr K Shadad Frank J Sullivan Joseph D Martin Laurence J Egan Department of Gastroenterology University Hospital GalwayUniversity Hospital Galway34562 GalwayIreland Department of Pharmacology and Therapeutics School of MedicineUniversity Hospital Galway34562 GalwayIreland Department of Radiation Oncology National University of Ireland GalwayUniversity Hospital Galway34562 GalwayIreland

With the recent advances in detection and treatment of cancer,there is an increasing emphasis on the efficacy and safety aspects of cancer *** therapy is a common treatment for a wide variety of cancers,either alone or in combination with other *** radiation injury to the gastrointestinal tract is a frequent side effect of radiation therapy and a considerable proportion of patients suffer acute or chronic gastrointestinal symptoms as a *** side effects often cause morbidity and may in some cases lower the efficacy of radiotherapy *** injury to the gastrointestinal tract can be minimised by either of two strategies:technical strategies which aim to physically shift radiation dose away from the normal intestinal tissues,and biological strategies which aim to modulate the normal tissue response to ionising radiation or to increase its resistance to *** considerable improvement in the safety of radiotherapy treatment has been achieved through the use of modern optimised planning and delivery techniques,biological techniques may offer additional further *** agents have been used to prevent or minimize the severity of gastrointestinal injury induced by ionising radiation exposure,including biological,chemical and pharmacological *** this review we aim to discuss various technical strategies to prevent gastrointestinal injury during cancer radiotherapy,examine the different therapeutic options for acute and chronic gastrointestinal radiation injury and outline some examples of research directions and considerations for prevention at a pre-clinical level.

关键词： Radiation enteritis Radiation proctitis Prevention Treatment Gastrointestinal radiation injury

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Prevalence and associated risk factors of recurrent otitis media with effusion in children in Upper Egypt

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2021年第4期7卷 280-284页

作者： Khaled Saad abobakr abdelm.ghny Yasser F.Abdel-Raheem Eman Fathalla Gad Amira Elhoufey Department of Pediatrics Faculty of MedicineAssiut UniversityAssiutEgypt Department of ENT Faculty of MedicineAl-Azhar UniversityAssiutEgypt Department of Community Health Nursing Faculty of NursingAssiut UniversityEgypt Department of Community Health Nursing Alddrab University CollegeJazan UniversitySaudi Arabia

Objective:We conducted this study to determine the associations of possible risk factors and prevalence of recurrent otitis media with effusion(OME)in a cohort of children in Upper ***:This was a cross-sectional study undertaken in two tertiary referral centers in Upper *** of possible risk factors with prevalence of recurrent OME were ***-factor logistic regression analysis was done to recognize the statistically significant risk factors associated with recurrent ***:We collected the data of 2003 pediatric patients,of which 1016 were males(50.7%).A total number of 310 children have OME,including 159 males(51.3%).The prevalence rate of OME in our cohort was 15.5%.Multi-factor logistic regression analysis of the risk factors related to recurrent OME showed it was strongly associated with adenoid hypertrophy(P<0.0001),tonsil hypertrophy(P<0.0001),sinusitis(P<0.0001),posterior nostril polyps(P =0.009),allergic rhinitis(P<0.0001),recurrent URTIs(P=0.029)and gastroesophageal reflux(P=0.031).Conclusions: Our study showed that recurrent OME in children in Upper Egypt is a common multifactorial problem, especially in young age. In our locality, allergic rhinitis, recurrent upper respiratory tract infections, gastroesophageal reflux, adenoid and tonsil hypertrophy were the most important associated factors related to the etiopathogenesis of OME.

关键词： Otitis media with effusion Children Risk Prevalence Recurrent

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Design Optimization of Reinforced Concrete Frames

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Open Journal of Civil Engineering 2015年第1期5卷 74-83页

作者： abobakr A. A. Aga Fathelrahman M. Adam Saudi Automotive Services Company Jedah KSA Department of Civil Engineering Jazan University Jazan KSA Nile Valley University Khartoum Sudan

In this paper, a design optimization for the reinforced concrete plane frame structure has been done in order to minimize the cost of the concrete and steel for beams and columns by adopting the Artificial Neural Network (ANN) computational model trough the NeuroShell-2 software program. The design procedure conforms to the ACI-318-08 Code. The variables used for design optimization are the width, depth and the area of reinforced steel, including longitudinal reinforcement and shear reinforcement. A three-bay two-story RC frame is modeled with selecting different span length and different load cases. Acceptable design results are obtained from more than 50 examples which are subjected to all the constraints of the ACI Code, using different cross-section sizes and these results are used to train the NeuroShell-2 program. The results obtained demonstrate the efficiency of the ANN procedure for the multi story RC frame design.

关键词： Optimization Design RC Beam Design RC Column Design Artificial Neural Network

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Gastrointestinal radiation injury:Symptoms,risk factors and mechanisms

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World Journal of Gastroenterology 2013年第2期19卷 185-198页

Ionising radiation therapy is a common treatment modality for different types of cancer and its use is expected to increase with advances in screening and early detection of *** injury to the gastrointestinal tract is important factor working against better utility of this important therapeutic *** survivors can suffer a wide variety of acute and chronic symptoms following radiotherapy,which significantly reduces their quality of life as well as adding an extra burden to the cost of health *** accurate diagnosis and treatment of intestinal radiation injury often represents a clinical challenge to practicing physicians in both gastroenterology and *** the growing recognition of the problem and some advances in understanding the cellular and molecular mechanisms of radiation injury,relatively little is known about the pathophysiology of gastrointestinal radiation injury or any possible susceptibility factors that could aggravate its *** aims of this review are to examine the various clinical manifestations of post-radiation gastrointestinal symptoms,to discuss possible patient and treatment factors implicated in normal gastrointestinal tissue radiosensitivity and to outline different mechanisms of intestinal tissue injury.

关键词： Radiation enteritis Radiation proctitis Symptoms Pathophysiology Risk factors

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智能手机品牌营销策略研究 ——基于苹果与三星公司的比较分析

智能手机品牌营销策略研究 ——基于苹...

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作者：伊布（abobakr Abdullah Ali Al-koli）长安大学

学位级别：硕士

营销策略是组织成功的关键要素,执行良好的营销策略与概念化和制定策略一样重要。通过市场营销策略的实施,公司通过市场营销能力来利用稀缺资源,从而实现既定目标。营销策略是使公司能够研究和思考受限资源以扩大销售并完成领先的有效... 详细信息

营销策略是组织成功的关键要素,执行良好的营销策略与概念化和制定策略一样重要。通过市场营销策略的实施,公司通过市场营销能力来利用稀缺资源,从而实现既定目标。营销策略是使公司能够研究和思考受限资源以扩大销售并完成领先的有效途径。智能手机已经成为移动设备的主流,它开辟了所谓“智能时代”带来了整个世界人类生活和文化的变化。苹果和三星目前是全球智能手机行业的两大巨头。苹果的i Phone开辟了智能手机时代。与此相反,三星智能手机Galaxy对智能手机的普及起了至关重要的作用。这两家企业在智能手机市场上的营销策略如此深刻。它们带动了整个行业的发展,给其他企业创造了市场机会,也给其他企业带来了很大的压力。本论文的研究将分析苹果与三星在智能手机市场的增长和竞争情况以及苹果和三星两家智能手机市场现状,通过SWOT分析更深入地了解苹果和三星两家智能手机竞争状况。论文中将分析苹果和三星两家智能手机的营销策略,以便更深入地了解苹果和三星如何采用营销组合的四个组成部分来区分自己,不同的营销策略一样能取得优秀的成绩,以获得相对于竞争对手的优势。研究结果发现,苹果与三星市场营销策略主要有品牌策略和产品,苹果和三星公司利用这样的品牌形象和价值,让新产品更快被消费者认可。具有较高的研发能力和较低的推广成本,新产品和新服务可以更快地占领市场。然后通过提供高质量产品在全球消费者中建立和发展了自己的品牌形象和声誉。创新和新技术,创新者总是具有竞争优势,特别是当一项创新受到市场的积极欢迎时消费者会因为新奇感而觉得有吸引力。正是有益的创新和良好的品牌形象增加了智能手机的感知价值,弥补了竞争优势,使其在竞争激烈的智能手机市场中获得成功。定价策略以吸引更多的消费者,以吸引那些想买智能手机的消费者购买他们的产品。一个好的产品定价策略不仅有助于提高销售收入,而且有助于企业与客户建立良好的关系。该两家企业能够以惊人的新技术,一流的设计和稳定性相结合。凭借其卓越的营销策略以及强大的创新和开拓性技术,它们有许多机会细分市场,在这些市场中,两家企业可以渗透并确保领先地位。

关键词：智能手机营销策略竞争分析品牌形象 SWOT分析

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The Impact of Lean Manufacturing Practices on Sustainability Performance:A Natural Resource-Based View

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Journal of Modern Accounting and Auditing 2022年第3期18卷 115-130页

作者： Mohamed A.abobakr Magdy G.Abdel-Kader Ahmed F.Elbayoumi Cairo University CairoEgypt Nahda University Beni-SuefEgypt The American University in Cairo CairoEgypt

Drawing upon a Natural Resource-Based View(NRBV),this paper aims to propose a quantitative model that could be used to investigate whether Lean Manufacturing(LM)practices/tools can improve the three aspects of corporate sustainability performance(economic,environmental,and social).This paper is based on a theoretical study to develop a new model by reviewing the literature and proposing new ideas according to the Natural Resource-Based View(NRBV).Reviewing the literature showed that there is a significant association between LM practices/tools implementation and the improvement on three aspects of corporate sustainability performance(economic,environmental,and social).This paper provides insights to manufacturing managers about the ability of LM practices to reduce cost of operations and maximize the value provided to ***,it highlighted the importance of LM practices implementation to manage organizations’activities responsibly in terms of their environmental,social,and economic *** proposing such a quantitative model according to a NRBV,this study contributes to a broader understanding of how LM practices affect three pillars of sustainability.

关键词： Lean Manufacturing(LM) sustainability economic performance environmental performance social performance Natural Resource-Based View(NRBV)

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Improving Adherence to Prescribed Antidiabetics and Cardiovascular Medications in Primary Health Care Centers in Nyala City, South Darfur State-Sudan

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Pharmacology & Pharmacy 2013年第9期4卷 701-709页

作者： Ahmed Dahab Ahmed Asim Ahmed Elnour Mirghani Abd Elrahman Yousif Farah Hamad Farah Hasab Alrasoul Akasha Ahmed Osman abobakr Abasaeed College of Pharmacy and Health Sciences Ajman University of Sciences and Technology Ajman UAE College of Pharmacy Clinical Pharmacy Taif University Taif KSA Consultant Clinical Pharmacist Al Ain Hospital Abu Dhabi Health Services Company (SEHA) Al Ain UAE Department of Pharmacology College of Medicine and Health Sciences UAE University Al Ain UAE Revolving Drug Fund (RDF) Ministry of Health (MOH) Nyala Sudan Department of Pharmaceutics Faculty of Pharmacy Gezira University Medani Sudan Social and Clinical Pharmacy Department Faculty of Pharmacy Charles University Hradec Kralove Czech Republic Registration and Drug Control Department Ministry of Health Abu Dhabi UAE. The Epidemiological Laboratory (Epi-Lab) Khartoum Sudan

Aims: Prospective pharmacist’s interventions aimed to improve patient’s knowledge and behaviors to adhere to medications in patients with type 2 diabetes with or without cardiovascular medical conditions in primary health care (PHCs) centers in Nyala city, South Darfur State, Sudan. Methodology and Materials: 300 patients were enrolled for assessing adherence with the Brief Medication Questionnaire (BMQ) in ten PHCs in Nyala city. We assessed patients’ responses to BMQ pre-and post-interventions plan by: complex interventions, humanitarianism and disease outcomes determined by health-related outcomes (SF-36), glycosylated hemoglobin (HbA1c) and blood pressure. Results: BMQ scores have improved significantly in four screens (pre-and post-interventions): regimen [4.6 ± 0.2 to 1.8 ± 0.1;P = 0.001], belief [1.6 ± 0.3 to 0.3 ± 0.3;P = 0.007], recall [1.7 ± 0.2 to 0.6 ± 0.2;P = 0.043] and access screens [1.8 ± 0.1 to 0.4 ± 0.1;P = 0.005];which have indicated an improved patients’ adherence to medications. Percentage of subjects reaching target of post prandial blood glucose (PPBG) have increased from 28.0% to 49.3%;[P = 0.02] post interventions. PPBG mean values have decreased significantly from [11.1 ± 0.6 mmol/L to 8.1 ± 0.8 mmol/L;

关键词： Adherence Darfur Medications Nyala PHCs Sudan

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