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Multiple insecticide resistance/susceptibility status of Culex quinquefasciatus,principal vector of bancroftian filariasis from filaria endemic areas of northern India

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Asian Pacific Journal of Tropical Medicine 2011年第6期4卷 426-429页

作者： kaushal kumar abhay k sharma Sarita kumar Sunita Patel Manas Sarkar Chauhan LS Centre for Medical Entomology and Vector Management National Centre for Diseases Control22-Shamnath MargDelhi-110054India Regional Filariasis Training and Research Centre National Centre for Diseases ControlVaranasi-221010India

Objective:To understand the insecticide resistance status of Culex quinquefasciatus Say（Diptera: Culicidae）（***） to deltamethrin,cyfluthrin,permethrin,lambdacyhalothrin, DDT and malathion in filarial endemic areas of Uttar Pradesh,***:Insecticide susceptibility assays were performed on wild-caught adult female *** mosquitoes to deltamethrin（0.05%）,cyfluthrin（0.15%）,permethrin（0.75%）,lambdacyhalothrin （0.05%）,malathion（5.0%） and DDT（4.0%）,the discriminating doses recommended by the World Health Organisation（WHO）.Results:The data showed that *** is highly resistant to DDT and malathion;the mortality was 28.33%and 27.5%,respectively and incipient resistance to synthetic pyrethroids（deltamethrin,cyfluthrin,permethrin,and lambdacyhalothrin）, where mortality ranged from 95.83%in permethrin to 98.33%in cyfluthrin and lambdacyhalothrin. knockdown times(kDT50) in response to synthetic pyrethroids varied significantly between different insecticides（P<0.01） from 31.480 min for permethrin to 21.650 for cyfluthrin. Conclusions:The results presents here provide the status report of the insecticide resistance/ susceptibility of *** in major filaria endemic areas of northern India.

关键词： Insecticide resistance Filaria DDT Synthetic pyrethroid Malathion Culex quinquefasciatus

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Process parameters-weld bead geometry interactions and their influence on mechanical properties:A case of dissimilar aluminium alloy electron beam welds

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Defence Technology（防务技术） 2018年第2期14卷 137-150页

作者： P.Mastanaiah abhay sharma G.Madhusudhan Reddy Defence Research and Development Laboratory KanchanbaghHyderabadTelangana 500058India Indian Institute of Technology Hyderabad Kandi CampusSangareddyTelangana 502285India Defence Metallurgical Research Laboratory KanchanbaghHyderabadTelangana 500058India

Prediction of weld bead geometry is always an interesting and challenging research topic as it involves understanding of complex multi input and multi output system. The weld bead geometry has a profound impact on the load bearing capability of a weld joint, which in-turn decides the performance in real time service conditions. The present study introduces a novel approach of detecting a relationship between weld bead geometry and mechanical properties(e.g. tensile load) for the purpose of catering the best the process could offer. The significance of the proposed approach is demonstrated by a case of dissimilar aluminium alloy(AA2219 and AA5083) electron beam welds. A mathematical model of tensile braking load as a function of geometrical attributes of weld bead geometry is presented. The results of investigation suggests the effective thickness of weld-a geometric parameter of weld bead has the most significant influence on tensile breaking load of dissimilar weld joint. The observations on bead geometry and the mechanical properties(microhardness, ultimate tensile load and face bend angle) are correlated with detailed metallurgical analysis. The fusion zone of dissimilar electron beam weld has finer grain size with a moderate evaporation and segregation of alloying elements magnesium and copper *** mechanical properties of weld joint are controlled by optimum bead geometry and HAZ softening in weaker AA5083 Al alloy.

关键词： Electron beam welding AA2219 AA5083 Bead geometry Tensile breaking load

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Efficient discrete firefly algorithm for Ctrie based caching of multiple sequence alignment on optimally scheduled parallel machines

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CAAI Transactions on Intelligence Technology 2019年第2期4卷 92-100页

作者： Soniya Lalwani Harish sharma abhay Verma Rajesh kumar Department of Computer Science & Engineering Rajasthan Technical University Kota India Department of Electrical Engineering Malaviya National Institute of Technology Jaipur India

This study introduces a two-level strategy for efficient execution of multiple sequence alignment (MSA) of complex heterogeneous sequences. The two levels of the proposed technique are comprised of: designing the discrete firefly algorithm (DFFA) for the formation and implementation of makespan minimisation on parallel machines, followed by performing Ctrie-based caching for pairwise alignment to reduce the load on the data servers for handling multiple queries. The proposed strategy addresses a multi-client problem that aims to acquire the full advantage of the computational power of parallel connected machines. Further, it is shown that the inclusion of Ctrie as caching mechanism successively improves the performance of the system with accretion in several sequences. Performance of proposed DFFA is also compared with discrete versions of four swarm intelligence based algorithms at the criteria of makespan minimisation and the rate of convergence on two kinds of complex and diverse datasets. The work is unique in this sense: it is the first swarm-intelligence-based implementation for the addressed problem;it is so far the first approach for Ctrie based caching of the MSA on the scheduled parallel machines;hybridisation of DFFA with Ctrie for caching the MSA results is also a novel implementation.

关键词： strategy execution machines

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Bioprospection of marine actinomycetes: recent advances,challenges and future perspectives

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Acta Oceanologica Sinica 2019年第6期38卷 1-17页

作者： Swati sharma abhay B. Fulke Asha Chaubey CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM) CSIR-Innovation CentreMumbai 400053India Regional Centre CSIR-National Institute of Oceanography (CSIR-NIO)Mumbai 400053India CSIR-Indian Institute of Integrative Medicine Jammu180001India

In exploring new sources for economically important products, marine environment draws particular attention because of its remarkable diversity and extreme conditions;it is known to produce metabolic products of great value. It represents untapped source for the discovery of novel secondary metabolites with varying potential such as antibiotic, anti-tumor, antifouling and cytotoxic properties. Marine actinomycetes distributed throughout the marine environment from shallow to deep sea sediments have proved to be a finest source for this discovery. Secondary metabolites derived from marine actinomycetes have proved their worth in industries based on the research on their properties and wide range applications. Spotlight of the review is range of marine based actinomycetes products and significant research in this field. This shows the capability of marine actinomycetes as bioactive metabolite producers. Additionally, the present review addresses some effective and novel approaches of procuring marine microbial compounds utilizing the latest screening strategies of drug discovery from which traditional resources such as marine actinobacteria has decreased due to declining yields. The aim is in the context of promoting fruitful and profitable results in the near future. The recent surfacing of new technologies for bioprospection of marine actinomycetes are very promising, resulting in high quality value added products, and will be de?ning a new era for bioactive compounds with medical and biotechnological applications.

关键词： marine actinomycetes bioprospection commercial use bioactive compounds genome mining

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Uroflowmetric analysis and derivation of nomograms for normal paediatric Indian population between 5 to 15 years of age

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Asian Journal of Urology 2022年第2期9卷 125-131页

作者： abhay D.Mahajan Lakshman P.Singh Prashant P.Darakh Sandeep T.Bathe Martand G.Patil Arpit R.sharma Mahatma Gandhi Mission Medical College and Hospital AurangabadMaharashtraIn

Objective:We aimed to established normal uroflowmetric values and subsequently derived nomograms of _(max)imum flow rate(Q_(max))and average flow rate(Q_(avg))against voided volume(VV)in children aged 5-15 years at our ***:A total of 440 children underwent uroflowmetric evaluation with no history of urological,renal,psychiatric,or neurological disorder between 5 and 15 years of *** subject data regarding Q_(max),Q_(avg),VV,time to Q_(max),and flow time,as well as age,sex,height,and weight were *** the 440 children,around 300(68.18%)children could produce a normal flow rate at VV of more than 50 *** the remaining 140(31.82%)children,50.00%voided less than 50 mL,and remaining 50.00%had abnormal voiding pattern,staccato or interrupted(21.43%each)and plateau or tower shaped(3.57%each).Cases were divided into two age groups(5-9 years and 10-15 years),and uroflowmetric analysis was done between boys and girls in both age groups to derive nomograms of Q_(avg) and Q_(max).Results:Q_(max) and Q_(avg) flow nomograms were plotted for boys and *** Q_(max) for boys was 16.68 mL/s and for girls 20.69 mL/*** mean Q_(avg) values were 11.04 mL/s and 8.60 mL/s for girls and boys,*** Q_(max) and Q_(avg) values were higher in *** were significant increases in flow rates with increasing age,body surface area,and VV in both ***:Nomograms for Q_(max) and Q_(avg) may be a useful tool in evaluation of lower urinary tract disturbances in children.

关键词： Uroflowmetry Nomograms Pediatric Voided volume Flow rate

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