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Lactic Acidosis and Atrial Tachycardia: Unusual Presentations of Disseminated Burkitt-Like Lymphoma

Journal of Cancer Therapy 2012年第5期3卷 589-594页

作者： Hazem El-Osta abdulrahman abdulbaki Prakash Peddi Amol Takalkar James Cotelingam Diana Veillon Andres Vargas Nuri Akkus Gerhard C. Hildebrandt Department of Medicine Division of Cardiology Louisiana State University Health Sciences Center Shreveport USA Department of Medicine Division of Hematology oncology Louisiana State University Health Sciences Center Shreveport USA Department of Medicine Division of internal medicine Louisiana State University Health Sciences Center Shreveport USA Department of Nuclear Medicine Louisiana State University Health Sciences Center Shreveport USA Department of Pathology Louisiana State University Health Sciences Center Shreveport USA

Lactic acidosis is a rare complication of malignancies and is seen more frequently in high grade lymphoma and leukemia. Although, its pathogenesis is not well understood, it remains a surrogate of poor prognosis. Herein, we present a case of Burkitt-like lymphoma presenting with metabolic abnormalities including lactic acidosis and hypoglycemia along with atrial tachycardia. We will discuss the different mechanisms involved in these metabolic disturbances and we will provide insight on novel therapeutic strategies based on our understanding of the underlying pathophysiology.

关键词： Atrial Tachycardia Burkitt-Like Lymphoma B-Cell Lymphoma Intra-Cardiac Tumor Hypoglycemia Lactic Acidosis

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COVID-19 vaccine candidates and vaccine development platforms available worldwide

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Journal of Pharmaceutical Analysis 2021年第6期11卷 675-682页

作者： Nilgun Duman Zahraa ALzaidi Busra Aynekin Duygu Taskin Busra Demirors abdulbaki Yildirim Izem Olcay Sahin Faik Bilgili Eda Tahir Turanli Tommaso Beccari Matteo Bertelli Munis Dundar Department of Medical Genetics Dragos Hospital IstanbulBezmialem Vakif UniversityIstanbul34854Turkey Department of Biotechnology Faculty of Applied ScienceCukurova UniversityAdana01380Turkey Department of Medical Genetics Medical FacultyErciyes UniversityKayseri38030Turkey Department of Economics Faculty of Economics and Administrative SciencesErciyes UniversityKayseri38030Turkey Department of Molecular Biology and Genetics Faculty of ScienceAcibadem University34684IstanbulTurkey Department of Pharmaceutical Sciences University of PerugiaPerugia06123Italy MAGI'S LAB Trentino38068Italy

The pandemic caused by the worldwide spread of the coronavirus,which first appeared in 2019,has been named coronavirus disease 19(COVID-19).More than 4.5 million deaths have been recorded due to the pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),according to the World Health ***-19 Dashboard in September *** from the wildtype,other variations have been successfully transmitted early in the outbreak although they were not discovered until March *** in the SARS-CoV-2 genetic material,such as mutation and recombination,have the ability to modify the viral life span,along with transitivity,cellular tropism,and symptom *** processes are involved in introducing novel vaccines to the population,including vaccine manufacturing,preclinical studies,Food and Drug Administration permission or certification,processing,and ***-19 vaccine candidates have been developed by a number of public and private groups employing a variety of strategies,such as RNA,DNA,protein,and viral vectored *** comprehensive review,which included the most subsequent evidence on unique features of SARS-CoV-2 and the associated morbidity and mortality,was carried out using a systematic search of recent online databases in order to generate useful knowledge about the COVID-19 updated versions and their consequences on the disease symptoms and vaccine development.

关键词： COVID-19 vaccine Vaccine development platform Coronavirus outbreak SARS-CoV-2 variants Treatment

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Eczema Disease Detection and Recognition in Cloud Computing

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Computer Technology and Application 2016年第1期7卷 57-64页

作者： Azmi Shawkat abdulbaki Samir Abdulrasoul Khadim Saif Al-din M. Najim College of Computer Science & Info. Tech. University of Anbar Ramadi Iraq Dept. of Computer Science University of Al-Maarif College Ramadi Iraq

ED (eczema disease) is the most common form of skin inflammation in humans. Most of the skin disease is curable at initial stages with the advancement of technology. So, an early detection of skin disease can save the patient’s life and prevent theprogression of the disease. It is proposed to have a study on the diagnosis of ED using BpNN (backpropagation neural network) in cloud computing approach due to that BpNN is currently widespread research area in medicine and plays an important role in a decision support system. In this paper, an attempt has been made to make use of BpNN in the medical field along cloud computing to detect ED.

关键词： BpNN cloud computing EDD (eczema disease detection) Skin Inflammation GA (genetic algorithm)

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