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Impact of poly chlorinated biphenyl (Aroclor 1254) and vitamin C on antioxidant system of rat ventral prostate

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Asian Journal of Andrology 2004年第1期6卷 19-22页

作者： M. sridhar P. Venkataraman s. Dhanammal A. Arunkumar M.M. Aruldhas N. srinivasan J. Arunakaran Department of Endocrinology Dr. ALM Post Graduate Institute of Basic Medical Sciences University of MadrasTaramani Chennai 600 113 India

Aim: To evaluate the effect of polychlorinated biphenyls (PCB) and vitamin C on ventral prostatic antioxidant system in adult male rats. Methods: A group of 20 adult male rats were administered ip Aroclor 1254 in corn oil at a dose of 2 mg·kg-1·day-1 for 30 days. Ten control rats were administered only the vehicle. After 30 days the treated rats were divided at random into 2 sub-groups of 10 animals each. One sub-group received vitamin C at a dose of 500 mg·kg-1·day-1 for 10 days. The other group was maintained as Aroclor 1254 control. Twenty-four hours after the last treatment the rats were killed by decapitation. Ventral prostatic homogenate was prepared and used for the estimation of enzymatic antioxidants, including superoxide dismutase (sOD), catalase (CAT) and glutathione-s-transferase (GsT) and hydrogen peroxide (H2O2), lipid peroxidation (LPO) and prostatic acid phosphatase. The serum levels of total T3, total T4, TsH, testosterone and estradiol were also assayed. Results: The body weight and ventral prostatic weight were reduced in PCB treated rats. The activities of sOD, CAT, GsT and acid phosphatase were decreased while the levels of H2O2 and lipid peroxidation were increased in the ventral prostate of PCB treated rats. Administration of vitamin C restored these parameters. serum levels of thyroid hormones, estradiol and testosterone were decreased in PCB treated animals. Administration of vitamin C restored the thyroid hormone levels. Conclusion: PCB induces oxidative stress and decreases the antioxidant enzymes in the ventral prostate of adult male rats; the effects could be reversed by the administration of vitamin C.

关键词： polychlorinated biphenyls Aroclor 1254 ventral prostate antioxidants lipid peroxidation thyroid hormone vitamin C

浦项钢铁公司光阳厂用于生产超低碳钢的RH精炼技术的改进

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攀钢技术 1998年第1期21卷 72-75页

作者： alm,sB 杨冬梅

为了了解操作条件（提升气体的流量、真空度、连通管直径和顶吹氧）对２５０ｔＲＨ真空处理装置脱碳性能的影响，进行了试验和理论研究。根据用Ｃｕ作为示踪物进行的完全混合时间的测定试验，加大提升气体流量或加大真空度，可以有效地... 详细信息

为了了解操作条件（提升气体的流量、真空度、连通管直径和顶吹氧）对２５０ｔＲＨ真空处理装置脱碳性能的影响，进行了试验和理论研究。根据用Ｃｕ作为示踪物进行的完全混合时间的测定试验，加大提升气体流量或加大真空度，可以有效地缩短完全混合时间，但未观察到连通管内径的影响。加大连通管直径会促进冶炼超低砚钢时的脱碳过程。通过定向型多孔塞喷吹提升气体，可提高表现脱碳速度（Ｋｃ），生产超低碳时脱碳时间缩短。

关键词： RH精炼技术超低碳钢炼钢

为期5年的多中心开放式研究评估拉坦前列素作为青光眼治疗辅助用药的安全性

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世界核心医学期刊文摘（眼科学分册） 2005年第1期1卷 22-23页

作者：邢咏新 alm A schoenfelder J McDermott J Department ofNeuroscience Op hthalmolo-g yUniversityHospitalSE 75185Up psalaSweden.Dr

Objective:To evaluate the 5-year sa fety and efficacy of adjunctive 0.005%latanoprost once ***:Pa-tients with primary open-angle or exfoliation glaucoma who completed a 3-year,open-label,uncontrolled,prospective trial could enter a 2-year extension ***-resolution color photographs of irides were tak en at baseline and at 14subsequent *** were assessed for change in iris pigmentation compared with *** pressures and adverse events were re *** Outcome Measure:Development and progression of increased iris pigmentation over ***:Of the 519original patients,380enrolled in the extension phase with approx-imately 89%having an eye color known to be susceptible to color *** 5years,most p atients had no in-crease in iris pigmentation,but certain colored irides ex-hibited notably greater susceptibi lity than *** those whose irides did change,onset occur red during the first 8months in 74%and during the first 24months in 94%.No patient developed an increase in pig mentation after month36;the rate of progression decrease d over *** event profiles were similar for pati ents with and without increased *** overall mean intraocular pressure reduction from baseline of25%was sustained with no need for change in intraocular pre ssure-lowering treat-ment in 70%of the ***:L atanoprost therapy is safe and well tolerated for long-term treatment of open-angle glaucoma.

关键词：青光眼治疗拉坦辅助用药剥脱性青光眼开角型青光眼色素改变眼内压辅助性治疗高分辨率彩色延长期

霍乱弧菌01群E1 Tor型溶血素的氨基末端区在古典型菌株中的表达及其细胞毒性

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微生物学免疫学进展 1992年第3期20卷 27-28,43页

作者： Richard A.alm 王叙亭

产生霍乱毒素(CT)的01群霍乱弧菌引起人霍乱。某些非01群霍乱弧菌株能产生与霍乱毒素相似的肠毒素,而另一些来自临床腹泻病例的非01群菌却不产生这种毒素,这表明还有其它因素能引起腹泻反应。现已证明这些菌株能产生溶血素——一种可能... 详细信息

产生霍乱毒素(CT)的01群霍乱弧菌引起人霍乱。某些非01群霍乱弧菌株能产生与霍乱毒素相似的肠毒素,而另一些来自临床腹泻病例的非01群菌却不产生这种毒素,这表明还有其它因素能引起腹泻反应。现已证明这些菌株能产生溶血素——一种可能的腹泻因素,尽管其致病机理尚不清楚。Yamamoto等人证实了非01群菌株和周群E1 Tor型菌株所产生的溶血素在生物学、理化住质和免疫学方面是难区分的。southern杂交分析表明两者的基因基本上是相同的。

关键词：霍乱弧菌01群溶血素氨基末端区菌株细胞毒性

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时尚的偶像永恒的经典小礼服

LONG -TERM sAFETY OF PROsTAGL - ANDINs IN THE EYE

丛书名：图解时装大师

2016年

作者：（美）莎拉·阿尔墓（sARA alm）汉娜·麦蒂维（HANNAH MCDEVITT）柯瑞·汉斯（KERRIE HEss）图片谢琛译

这些美丽超凡的女子身着美丽超凡的小礼服，奥黛丽的小黑裙、玛丽莲的经典白色褶裥裙、杰奎琳的一字领A型裙等，至今仍然让我们为之眩目。《时尚的偶像永恒的经典小礼服》为你提供了自己动手制作这些经典小礼装所需要的一切：经典的... 详细信息

ISBN: (纸本)7518020973

这些美丽超凡的女子身着美丽超凡的小礼服，奥黛丽的小黑裙、玛丽莲的经典白色褶裥裙、杰奎琳的一字领A型裙等，至今仍然让我们为之眩目。《时尚的偶像永恒的经典小礼服》为你提供了自己动手制作这些经典小礼装所需要的一切：经典的黑白老照片，唤起我们的记忆；彩色线条的时装效果图，启发着我们的创作灵感；号型尺寸齐全的1：1纸样，可按s/M/L号直接剪裁制作；分步绘制的缝制插图，让大家都可以跟上工艺的步骤； 10款经典小礼服的制作细节说明，再加上10款根据当代时尚流行稍作改进的变化款设计，本书为您提供20款小礼服的样式。这本《时尚的偶像永恒的经典小礼服》既原汁原味又完整齐全的时装工艺书是送给所有喜更多...

关键词：图解服装量裁女服

来源：汇雅图书（南通市图书馆... 畅想之星图书光盘版（南... 评论

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国际眼科杂志 2003年第1期3卷 117-117页

作者： A.alm Department of Neuroscience/Ophthalmology Uppsala University Sweden

Initial studies on the use of prostaglandins in the human eye were made with prostaglandin F2alpha but local side effects initiated the development of prostaglandin analogs. Topically applied prostaglandin analogues h... 详细信息

关键词：前列腺素类似物人眼长期用药治疗安全性副作用预防

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微裂隙和花岗岩的抗拉强度

力学学报 1987年第4期 366-373页

作者：寇绍全 O.alm 中国科学院力学研究所瑞典吕勒欧大学

本文在对不同温度热处理的花岗岩试件的裂隙微观特征及宏观力学性质的考察之后,建立了抗拉强度与微裂隙密度的关系。在理论模型要求的范围内,理论与实验结果吻合较好。该工作对设计储藏核废料,化学废料,热水和液化气的岩石仓库有参考... 详细信息

本文在对不同温度热处理的花岗岩试件的裂隙微观特征及宏观力学性质的考察之后,建立了抗拉强度与微裂隙密度的关系。在理论模型要求的范围内,理论与实验结果吻合较好。该工作对设计储藏核废料,化学废料,热水和液化气的岩石仓库有参考价值。

关键词：微裂隙抗拉强度花岗岩损伤

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新疆特种乳乳间掺伪检测技术的研究

新疆特种乳乳间掺伪检测技术的研究

作者：阿力木·吾布力（alm·UBUL）新疆大学

学位级别：硕士

特种乳是指除牛乳之外的其他家畜的乳。本文以新疆双峰驼乳、驴乳、山羊乳和牛乳为研究对象,采用sDs-PAGE,RP-HPLC方法检测特种乳与牛乳间乳清蛋白的差异组分;采用双重PCR特异性扩增不同乳种线粒体DNA,通过三种不同的方法分析检测新疆... 详细信息

特种乳是指除牛乳之外的其他家畜的乳。本文以新疆双峰驼乳、驴乳、山羊乳和牛乳为研究对象,采用sDs-PAGE,RP-HPLC方法检测特种乳与牛乳间乳清蛋白的差异组分;采用双重PCR特异性扩增不同乳种线粒体DNA,通过三种不同的方法分析检测新疆特种乳(驼乳、驴乳和山羊乳)中牛乳的掺伪,综合评价这三种方法的优越性,为建立新疆特种乳掺伪牛乳的快速检测方法提供实验依据。主要研究结果为:***-PAGE检测新疆特种乳中掺伪的牛乳成分。通过sDs-PAGE检测新疆特种乳乳清与牛乳乳清间的差异蛋白质,其中新疆双峰驼驼乳乳清、山羊乳乳清和驴乳乳清相对于牛乳乳清分别缺失β-乳球蛋白,乳铁蛋白,ɑ-乳白蛋白。通过检测特种乳中缺失的牛乳蛋白,新疆双峰驼驼乳、山羊乳和驴乳中掺伪牛乳的最低检出限分别为1:10、1:4和1:10(V/V)。2.双重PCR的方法检测新疆特种乳中掺伪的牛乳成分。通过双重PCR特异性扩增牛乳、驼乳,山羊乳,驴乳的线粒体DNA,目的条带分别为223bp,200bp,157 bp,145bp。其中双重PCR检测驼乳、山羊乳、驴乳中掺伪牛乳的最低检出限分别为1:20、1:400和1:400(V/V)。***-HPLC检测新疆特种乳中掺伪的牛乳成分。通过RP-HPLC检测新疆特种乳与牛乳间乳清蛋白的差异,其中新疆双峰驼驼乳乳清、山羊乳乳清和驴乳乳清分别缺失β-乳球蛋白,乳铁蛋白,ɑ-乳白蛋白。其中驼乳、山羊乳、驴乳中掺伪牛乳的最低检出限分别为1:200、1:200和1:100(V/V)。结果表明,PCR,HPLC检测牛乳掺假灵敏度较高,考虑经验成本和时间,sDs-PAGE在检测新疆特种乳中掺伪牛乳具有优势,但灵敏度较差。

关键词：特种乳掺伪检测技术 sDs-PAGE RP-HPLC PCR

Psychometric evaluation of a swedish version of Krantz Health Opinion survey

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Open Journal of Nursing 2012年第3期2卷 181-187页

作者： Petra svedberg Bodil Ivarsson Ulrica G Nilsson Asa Roxberg Amir Baigi David Brunt Margareta Brannstrom Bengt Fridlund sylvi Persson Mikael Rask Carin alm-Roijer school of social and Health sciences Halmstad UniversityHalmstadSweden Department of Cardiothoracic surgery University Hospital of LundLundSweden Centre of Health Care sciences Orebro University Hospital OrebroSweden University College of Haraldsplass BergenNorway school of Health and Caring sciences Linnaeus UniversityVaxjoSweden General Practice and Public Health Halland County CouncilFalkenbergSweden Department of Nursing Umea UniversityUmeaSweden school of Health sciences Jonkoping UniversityJonkopingSweden The Faculty of Health and society Malmo UniversityMalmoSweden

The purpose of this study was to evaluate the psychometric properties of a swedish version of The Krantz Health Opinion survey (KHOs). A convenience sample of 79 persons (47 men and 32 women) was recruited from The Heart and Lung Patients’ National Association at ten local meeting places in different areas in sweden. The questionnaire was examined for face and content validity, internal consistency and test-retest reliability. The findings showed that the swedish version of KHOs is acceptable in terms of face and content validity, internal consistency and test-retest reliability over time among 79 individuals >65 years of age and with a cardiac disease. In conclusion, wider evaluations of the psychometric use of KHOs for other populations and settings are recommended.

关键词： Heart Diseases Consumer Health Information Questionnaire Reliability Content Validity