检索结果-南通市图书馆

Central role of altered phosphodiesterase 2-dependent signaling in the pathophysiology of cognition-based brain disorders

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2302-2303页

作者： asma Boulksibat Alessandra Tempio Barbara Bardoni Institut de Pharmacologie Moléculaire et Cellulaire CNRS UMR7275Inserm U1323ValbonneFrance

The second messengers 3',5'-cyclic adenosine monophosphate(cAMP)and 3',5'-cyclic guanosine monophosphate(cGMP)modulate molecular pathways that are involved in a large variety of cellular *** the brain,these processes include neurogenesis,neuronal differentiation,activation and function of microglia,and synaptic plasticity,finally resulting in memory formation.

关键词： formation processes finally

Energy Efficiency of a Solar Green Building Using Bio-Sourced Materials for Indoor Temperature and Humidity Optimization

在线全文

学校读者我要写书评

暂无评论

Energy Engineering 2025年第1期122卷 41-62页

作者： SoumiaMounir Youssef Maaloufa Abdelhamid Khabbazi ElinaMohd Husini Nurul SyalaAbdul Latip YakubuAminuDodo Rime ELHarrouni MinaAmazal asma Souidi Malika Atigui Ahmed Aharoune National School of Architecture Agadir New Complex Ibn ZohrAgadirBP 20732Morocco EMDD CERNE2DUniversity of Mohammed V in RabatEst SaleSaleBP 227Morocco Thermodynamics and Energetics Laboratory Faculty of ScienceIbn Zohr UniversityAgadirBP 8106Morocco Faculty of Built Environment University Sains Islam MalaysiaNilaiBP 71800Malaysia Architectural Engineering Department Najran UniversityNajranBP 1988Saudi Arabia The Centre of Scientific and Engineering Research Najran UniversityNajranBP 1988Saudi Arabia Euro-Mediterranean School of Architecture Design and UrbanismEuro-Mediterranean University of FezFezBP 51Morocco

A clean environment with low carbon emissions is the goal of research on the development of green and sustainable buildings that use bio-sourced materials in conjunction with solar energy to create more sustainable *** is particularly true in Africa,where there aren’t many studies on the *** current study suggests a 90 m^(2) model of a sustainable building in a dry climate that is movable to address the issue of housing in remote areas,ensures comfort in harsh weather conditions,uses solar renewable resources—which are plentiful in Africa—uses biosourced materials,and examines how these materials relate to temperature and humidity control while emitting minimal carbon *** order to solve the topic under consideration,the work is split into two sections:numerical and experimental *** TRNSYS and Revit,the suggested prototype building is examined numerically to examine the impact of orientation,envelope composition made of bio-sourced materials,and carbon *** a hygrothermal investigation,experiments are conducted to evaluate this prototype’s ***,an examination of the photovoltaic system’s production,consumption,and several scenarios used tomaximize battery life is included in the *** the biosourcedmaterial achieves a thermal transmittance of 0.15(W.m^(-2).K^(-1)),the results demonstrate an intriguing finding in terms of *** value satisfies the requirements of passive building,energy autonomy of the dwelling,and injection in-network with an annual value of 15,757 ***,compared to the literature,the heating needs ratio is 6.38(kWh/m^(2).an)and the cooling needs ratio is 49(kWh/m^(2).an),both of which are good *** to international norms,the inside temperature doesn’t go above 26℃,and the humidity level is within a comfortable range.

关键词： Bio-sourced materials energy sustainability green architecture built environment

Nano-Enhanced Dairy Scum Biodiesel Blends:Unleashing the Power of Aluminium Oxide for Sustainable and Efficient Engine Performance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2025年第1期 283-302页

作者： Veeranna MODI Prasad B.RAMPURE Sunil Kumar SHETTY Madeva NAGARAL Channa Keshava NAIK N Johar MGM Muhammad Irsyad abdullah abdullah I.AL-MANSOUR Shamshad ALAM KLE College of Engineering and Technology ChikodiVisvesvaraya Technological University Nitte (Deemed to be University) NMAM Institute of Technology (NMAMIT)Department of Mechanical Engineering Aircraft Research and Design Centre HAL Department of Mechanical Engineering BGS College of Engineering and TechnologyBengaluruAffiliated to Visvesvaraya Technological University Management and Science University Department of Civil Engineering College of EngineeringKing Saud University

This study investigates the effect of aluminium oxide nanoparticlesaddition to biodiesel blends made from dairy milk scum on performance and combustion characteristics of the diesel *** dispersion of Al2O3nanoparticles in B20 blends at different concentrations was done with the help of *** number of blends were prepared for the *** Machine learning algorithms(Random Forest（RF）and CatBoost) was used for the *** results show that in comparison to biodiesel blends without nanoparticles,the kinematic viscosity and density is higher for fuel blends with *** these Fuel blends have higher calorific *** blends exhibited reduced Brake Specific Fuel Consumption（BSFC） of2.85% than the blends without nano particles(Dairy Scum Methyl Ester Biodiesel 20%+Neat Diesel 80%（in volume）,DSMEB20),57.14% less CO,40.8% less hydrocarbon,and increased NOxemissions compared to conventional diesel,contributing to the development of environmentally friendly and renewable biofuel blends with *** B20NP30 is the optimal blend for performance and emission *** study concludes with findings on enhanced Brake Thermal Efficiency（BTE） of 26.29% in 3×10-5（in volume） Al2O3nanoparticle-blended DSME B20 and other DSME B20 fuel blends,emphasizing the importance of optimal nanoparticle *** correlation matrix shows how engine load,efficiency measures（BTE,BSFC）,and emissions（CO,CO2,NOx,Smoke） are connected in complex *** results help us understand the complicated dynamics of engine performance and emission characteristics ***'s diagram for BTE and BSFC shows that CatBoost-based BTE models perform superior to RF-based models during the training as well as testing *** results were obtained for CO and CO2emission results.

关键词：

Decoding molecular mechanisms:brain aging and Alzheimer's disease

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2279-2299页

作者： Mahnoor Hayat Rafay Ali Syed Hammad Qaiser Mohammad Uzair Khalid Al-Regaiey Roaa Khallaf Lubna abdullah Mohammed Albassam Imdad Kaleem Xueyi Wang Ran Wang Mehwish SBhatti Shahid Bashir Atta-ur-Rahman School of Applied Biosciences(ASAB) National University of Sciences and Technology(NUST)IslamabadPakistan Department of Biotechnology Quaid-i-Azam UniversityIslamabadPakistan Department of Biological Sciences Faculty of Basic&Applied SciencesInternational Islamic University Islamabad(IIUI)IslamabadPakistan Department of Bioengineering King Fahd University of Petroleum and MineralsDhahranSaudi Arabia Department of Physiology College of MedicineKing Saud UniversityRiyadhSaudi Arabia Department of Neurology Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Mental Health Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Biosciences Commission on Science and Technology for Sustainable Development in the South(COMSATS University)IslamabadPakistan Department of Psychiatry The First Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Mental Health Institute of Hebei Medical University ShijiazhuangHebei ProvinceChina Department of Neurobiology and Behavior University of CaliforniaIrvineCAUSA Neuroscience Center King Fahad Specialist Hospital DammamDammamSaudi Arabia

The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for *** aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's *** these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging *** these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect *** review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.

关键词： Alzheimer’s disease brain aging cognitive health dementia molecular mechanisms neuronal activity neuroplasticity neurotransmission

THE DYNAMIC BUCKLING OF AN ORTHOTROPIC CYLINDRICAL THIN SHELL UNDER TORSION VARYING AS A POWER FUNCTION OF TIME

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2003年第1期16卷 81-87页

作者： Sofiyev abdullah A1 Ay Zeki A1 Sofuyev Ali A2 Department of Civil Engineering Suleyman Demirel University Isparta Turkey Kazakh Filial Tech. Sci. Department Gence Pedagogic University Kazakh Azerbaijan

The subject of this investigation is to study the buckling of orthotropic cylindrical thin shells under torsion, which is a power function of time. The dynamic stability and compatibility equations are obtained first. These equations are subsequently reduced to a time dependent differential equation with variable coefficient by using Galerkin's method. Finally, the critical dynamic and static loading, the corresponding wave numbers, the dynamic factors, critical time and critical impulse are found analytically by applying the Ritz type variational method. Using those results, the effects of the variations of the power of time in the torsion load expression, of the loading parameter, the ratio of the Young's moduli and the ratio of the radius to thickness on the critical parameters are studied numerically. It is observed that these factors have appreciable effects on the critical parameters of the problem in the heading.

关键词： dynamic buckling cylindrical shells torsion dynamic critical load dynamic factor critical impulse

Ammoniacal Nitrogen and Organics Removal Modelling in Vertical Flow Wetlands Treating Strong Wastewaters

在线全文

学校读者我要写书评

暂无评论

湿地科学 2013年第4期11卷 421-432页

作者： Tanveer Ferdous Saeed abdullah A1 Muyeed Guangzhi Sun Department of Civil Engineering Ahsanullah University of Science and Technology Dhaka Bangladesh School of Engineering and Physical Sciences James Cook University Townsville QLD 4811 Australia)

This paper reports a comparative evaluation between 2 kinetic models for predicting nitrification and biodegradable organics(BOD5)removal rates in 5 vertical flow(VF)wetland systems,that received strong wastewaters(***,textile and municipal effluents).The models were formulated by combining first order and Monod kinetics,with continuous-stirred tank reactor(CSTR)flow *** performance of the 2 models had been evaluated with3 statistical parameters:coefficient of determination(R2),relative root mean square error(RRMSE),and model efficiency(ME).The statistical parameters indicated better performance of the Monod CSTR model(over first order CSTR approach),for correlating ammoniacal nitrogen(NH4+—N)and BOD5removal profiles across VF *** Monod coefficient values(from Monod CSTR model)coincided with greater input NH4+—N and BOD5loading,and experimentally measured removal rate(g/(m2·d))*** trends indicate that NH4+—N and BOD5removals in the VF systems were mainly achieved via biological *** the other hand,the rate constants(from the first order CSTR model)did not exhibit such correlations(of Monod coefficients),elucidating their inefficiencies in capturing overall removal *** interference of organics removal on nitrification process(in VF wetlands)was identified through Monod *** deviation between NH4+—N and BOD5Monod coefficients imply incorporation of both coefficients,for calculating the area of a single VF ***,closer performance of the Monod CSTR model for predicting NH4+—N and BOD5removals indicate its potential application,as a design tool for VF systems.

关键词： CSTR 废物处理技术方法 BOD

Access Pricing to An Operating System Platform when Piracy Matters

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Science and Systems Engineering 2020年第2期29卷 184-202页

作者： asma Brahem Khaireddine Jebsi Faculty of Management and Economic Sciences of Sousse University of SousseTunisia

This paper examines the impact of piracy on access pricing strategy of an operating system *** study the behavior of users and developers due to an increase in software protection when positive network externalities *** show that when piracy cost increases,access demands to the platform vary in the same direction and the magnitude of this variation depends on both the marginal network benefit that a developer derives and a certain threshold of piracy *** into account the behavior of these two sides when piracy matters,the monopoly platform changes its pricing *** show that,it tends to reduce or to increase access ***,we show that under certain conditions,the divide-and-conquer pricing strategy can be reversed.

关键词： Platform software developers piracy two-sided market single-homing

Hybrid Color Texture Features Classification Through ANN for Melanoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Intelligent Automation & Soft Computing 2023年第2期35卷 2205-2218页

作者： Saleem Mustafa Arfan Jaffar Muhammad Waseem Iqbal asma Abubakar abdullah S.Alshahrani Ahmed Alghamdi Faculty of Computer Science&Information Technology Superior UniversityLahore54600Pakistan Department of Software Engineering Superior UniversityLahore54600Pakistan Department of Computer Science&Artificial Intelligence College of Computer Science&EngineeringUniversity of Jeddah21493Saudi Arabia Department of Software Engineering College of Computer Science and EngineeringUniversity of Jeddah21493Saudi Arabia

Melanoma is of the lethal and rare types of skin *** is curable at an initial stage and the patient can survive *** is very difﬁcult to screen all skin lesion patients due to costly *** are requiring a correct method for the right treatment for dermoscopic clinical features such as lesion borders,pigment networks,and the color of *** challenges are required an automated system to classify the clinical features of melanoma and non-melanoma *** trained clinicians can overcome the issues such as low contrast,lesions varying in size,color,and the existence of several objects like hair,reﬂections,air bubbles,and oils on almost all *** contour is one of the suitable methods with some drawbacks for the segmentation of irre-gular *** entropy and morphology-based automated mask selection is pro-posed for the active contour *** proposed method can improve the overall segmentation along with the boundary of melanoma *** this study,features have been extracted to perform the classiﬁcation on different texture scales like Gray level co-occurrence matrix(GLCM)and Local binary pattern(LBP).When four different moments pull out in six different color spaces like HSV,Lin RGB,YIQ,YCbCr,XYZ,and CIE L*a*b then global information from different colors channels have been ***,hybrid fused texture features;such as local,color feature as global,shape features,and Artiﬁcial neural network(ANN)as classiﬁers have been proposed for the categorization of the malignant and *** had been carried out on datasets Dermis,DermQuest,and *** results of our advanced method showed super-iority and contrast with the existing state-of-the-art techniques.

关键词： Gray level co-occurrence matrix local binary pattern artiﬁcial neural networks support vector machines color skin cancer dermoscopic

An Online Fake Review Detection Approach Using Famous Machine Learning Algorithms

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第2期78卷 2767-2786页

作者： asma Hassan Alshehri Department of Computer Sciences College of Computer Engineering and SciencesPrince Sattam bin Abdulaziz UniversityAl KharjSaudi Arabia

Online review platforms are becoming increasingly popular,encouraging dishonest merchants and service providers to deceive customers by creating fake reviews for their goods or *** Sybil accounts,bot farms,and real account purchases,immoral actors demonize rivals and advertise their *** academic and industry efforts have been aimed at detecting fake/fraudulent product or service evaluations for *** primary hurdle to identifying fraudulent reviews is the lack of a reliable means to distinguish fraudulent reviews from real *** paper adopts a semi-supervised machine learning method to detect fake reviews on any website,among other *** reviews are classified using a semi-supervised approach(PU-learning)since there is a shortage of labeled data,and they are ***,classification is performed using the machine learning techniques Support Vector Machine(SVM)and Nave *** performance of the suggested system has been compared with standard works,and experimental findings are assessed using several assessment metrics.

关键词： Security fake review semi-supervised learning ML algorithms review detection