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Analysis of particle dispersion and cavity formation during bulk particle water entry using fully coupled CFD-DEM-VOF approach

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Particuology 2024年第7期90卷 558-580页

作者： Utkan Çalışkan Sanja Mišković Norman B.Keevil Institute of Mining Engineering University of British Columbia2329 West MallVancouverBC V6T 1Z4Canada

This paper presents the development and validation of a fully coupled computational fluid dynamics—discrete element method—volume of fluid(CFD-DEM-VOF)model to simulate the complex behavior of particle-laden flows with free *** coupling between the fluid and particle phases is established through the implemented continuity,momentum,and alpha transport *** coupled particle forces such as drag,pressure gradient,dense virtual mass,viscous,and interface forces are also integrated,with drag and dense virtual mass forces being dependent on local *** integrated conservative alpha transport equation ensures phase volume conservation during interactions between particles and ***,we have implemented a trilinear interpolation method designed to operate on unstructured hexahedral *** method has been tested for its ability to properly resolve the coupling effects in the numerical simulations,particularly in cases with a relatively low cell-size *** model is validated through three distinct test cases:single particle water entry,dam break with particles,and water entry of a group of particles *** experimental setup is built to study the dynamics of the water entry of a group of particles,where three key flow features are analyzed:the evolution of average particle velocity,cavity shape,and particle dispersion cloud profiles in *** tests involve four different scenarios,including two different water levels(16.1 and 20.1 cm)and two different particle densities(2650 and 4000 kg/m3).High-speed videometry and particle tracking velocimetry(using ImageJ/TrackMate)methods are employed for experimental data *** is demonstrated that numerical results are in excellent agreement with theoretical predictions and experimental *** study highlights the significance of vortices in cavity shaping and particle *** validated CFD-DEM-VOF model constitutes a robust tool for simulating particle-laden flows,cont

关键词： CFD-DEM-VOF Trilinear interpolation Particle-laden flow Free-surface Particle water entry Volume conservation

Blade Wrap Angle Impact on Centrifugal Pump Performance:Entropy Generation and Fluid-Structure Interaction Analysis

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Computer Modeling in Engineering & Sciences 2024年第7期140卷 109-137页

作者： Hayder Kareem Sakran Mohd Sharizal abdul Aziz Chu Yee Khor School of Mechanical Engineering Universiti Sains MalaysiaEngineering CampusNibong TebalPenang14300Malaysia Chemical Engineering Department Faculty of EngineeringAl-Muthanna UniversityMuthanna66001Iraq Faculty of Mechanical Engineering&Technology Universiti Malaysia Perlis(UniMAP)ArauPerlis02600Malaysia

The centrifugal pump is a prevalent power equipment widely used in different engineering patterns,and the impeller blade wrap angle significantly impacts its performance.A numerical investigation was conducted to analyze the influence of the blade wrap angle on flow characteristics and energy distribution of a centrifugal pump evaluated as a low specific speed with a value of *** study investigates six impellermodels that possess varying blade wrap angles(95°,105°,115°,125°,135°,and 145°)that were created while maintaining the same volute and other geometrical *** investigation of energy loss was conducted to evaluate the values of total and entropy generation rates(TEG,EGR).The fluid-structure interaction was considered numerically using the software tools ANSYS Fluent and *** elastic structural dynamic equation was used to estimate the structural response,while the shear stress transport k–ωturbulence model was utilized for the fluid domain *** findings suggest that the blade wrap angle has a significant influence on the efficiency of the *** impeller featuring a blade wrap angle of 145°exhibits higher efficiency,with a notable increase of 3.76%relative to the original *** in the blade wrap angle impact the energy loss,shaft power,and pump *** model with a 145°angle exhibited a maximum equivalent stress of 14.8MPa and a total deformation of 0.084 *** results provide valuable insights into the intricate flow mechanism of the centrifugal pump,particularly when considering various blade wrap angles.

关键词： Centrifugal pump blade wrap angle entropy generation theory fluid-structure interaction hydraulic performance

Embryonic thermal manipulation:a potential strategy to mitigate heat stress in broiler chickens for sustainable poultry production

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1347-1375页

作者： Sadid al Amaz Birendra Mishra Department of Human Nutrition Food and Animal SciencesCollege of Tropical Agriculture and Human ResourcesUniversity of Hawaii at ManoaAgSci 2161955 East‑West RdHonoluluHI 96822USA

Due to high environmental temperatures and climate change, heat stress is a severe concern for poultry health and production, increasing the propensity for food insecurity. With climate change causing higher temperatures and erratic weather patterns in recent years, poultry are increasingly vulnerable to this environmental stressor. To mitigate heat stress, nutritional, genetic, and managerial strategies have been implemented with some success. However, these strategies did not adequately and sustainably reduce the heat stress. Therefore, it is crucial to take proactive measures to mitigate the effects of heat stress on poultry, ensuring optimal production and promoting poultry well-being. Embryonic thermal manipulation(TM) involves manipulating the embryonic environment's temperature to enhance broilers' thermotolerance and growth performance. One of the most significant benefits of this approach is its cost-effectiveness and saving time associated with traditional management practices. Given its numerous advantages, embryonic TM is a promising strategy for enhancing broiler production and profitability in the poultry industry. TM increases the standard incubation temperature in the mid or late embryonic stage to induce epigenetic thermal adaption and embryonic metabolism. Therefore, this review aims to summarize the available literature and scientific evidence of the beneficial effect of pre-hatch thermal manipulation on broiler health and performance.

关键词： Broiler Embryo Epigenetics Global warming Thermoregulation

Extracellular vesicles as tools and targets in therapy for diseases

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Signal Transduction and Targeted Therapy 2024年第3期9卷 872-912页

作者： Mudasir A.Kumar Sadaf K.Baba Hana Q.Sadida Sara al.Marzooqi Jayakumar Jerobin Faisal H.altemani Naseh algehainy Mohammad A.alanazi abdul-Badi Abou-Samra Rakesh Kumar Ammira S.al-Shabeeb Akil Muzafar A.Macha Rashid Mir Ajaz A.Bhat Watson-Crick Centre for Molecular Medicine Islamic University of Science and TechnologyAwantiporaKashmir 192122India Department of Human Genetics-Precision Medicine in Diabetes Obesity and Cancer ProgramSidra MedicineDohaQatar Qatar Metabolic Institute Academic Health SystemHamad Medical CorporationDohaQatar Department of Medical Laboratory Technology Prince Fahad Bin Sultan Chair for Biomedical ResearchFaculty of Applied Medical SciencesUniversity of TabukTabukSaudi Arabia School of Biotechnology Shri Mata Vaishno Devi UniversityKatraIndia

Extracellular vesicles(EVs)are nano-sized,membranous structures secreted into the extracellular *** exhibit diverse sizes,contents,and surface markers and are ubiquitously released from cells under normal and pathological *** serum is a rich source of these EVs,though their isolation from serum proteins and non-EV lipid particles poses *** vesicles transport various cellular components such as proteins,mRNAs,miRNAs,DNA,and lipids across distances,influencing numerous physiological and pathological events,including those within the tumor microenvironment(TME).Their pivotal roles in cellular communication make EVs promising candidates for therapeutic agents,drug delivery systems,and disease *** in cancer diagnostics,EV detection can pave the way for early identification and offers potential as diagnostic ***,various EV subtypes are emerging as targeted drug delivery tools,highlighting their potential clinical *** need for non-invasive biomarkers to monitor biological processes for diagnostic and therapeutic purposes remains *** into the unique composition of EVs could unlock advanced diagnostic and therapeutic avenues in the *** this review,we discuss in detail the roles of EVs across various conditions,including cancers(encompassing head and neck,lung,gastric,breast,and hepatocellular carcinoma),neurodegenerative disorders,diabetes,viral infections,autoimmune and renal diseases,emphasizing the potential advancements in molecular diagnostics and drug delivery.

关键词： diseases sized sizes

Deep eutectic solvents:Green multi-task agents for sustainable super green hydrogen technologies

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Journal of Energy Chemistry 2024年第5期92卷 357-382页

作者： Raiyan al-Farsi Maan Hayyan Renewable Energy Engineering Program Faculty of Engineering and TechnologyMuscat UniversityMuscat 130Oman Chemical Engineering Program Faculty of Engineering and TechnologyMuscat UniversityMuscat 130Oman

While reliance on renewable energy resources has become a reality, there is still a need to deploy greener and more sustainable methods in order to achieve sustainable development goals. Indeed, green hydrogen is currently believed to be a reliable solution for global warming and the pollution challenges arising from fossil fuels, making it the resilient fuel of the future. However, the sustainability of green hydrogen technologies is yet to be achieved. In this context, generation of green hydrogen with the aid of deep eutectic solvents(DESs) as green mixtures has been demonstrated as a promising research area. This systematic review article covers green hydrogen generation through water splitting and biomass fermentation when DESs are utilized within the generation process. It also discusses the incorporation of DESs in fuel cell technologies. DESs can play a variety of roles such as solvent, electrolyte, or precursor;colloidal suspension and reaction medium;galvanic replacement, shape-controlling, decoration, or extractive agent;finally oxidant. These roles are relevant to several methods of green hydrogen generation, including electrocatalysis, photocatalysis, and fermentation. As such, it is of utmost importance to screen potential DES formulations and determine how they can function in and contribute throughout the green hydrogen mobility stages. The realization of super green hydrogen generation stands out as a pivotal milestone in our journey towards achieving a more sustainable form of development;DESs have great potential in making this milestone achievable. Overall, incorporating DESs in hydrogen generation constitutes a promising research area and offers potential scalability for green hydrogen production, storage,transport, and utilization.

关键词： Watersplitting Biohydrogen Super green hydrogen Electrocatalysis Photocatalysis Fuel cell Power-to-X

Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice

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Protein & Cell 2024年第9期15卷 661-685页

作者： Sadaf Hasan Nabil ghani Xiangli Zhao Julia Good Amanda Huang Hailey Lynn Wrona Jody Liu Chuan-ju Liu Department of Orthopedic Surgery New York University Grossman School of MedicineNew YorkNY 10016United States Department of Medicine Division of Internal MedicineSaint Peter’s University HospitalRutgers UniversityNew BrunswickNJ 08901United States Cornell University IthacaNew YorkNYUnited States Department of Biomedical Engineering University of North Carolina Chapel HillChapel HillNC 27599United States New York University NY 14853United States Department of Cell Biology New York University Grossman School of MedicineNew YorkNY 10016United States Department of Orthopedics&Rehabilitation Yale University School of MedicineNew HavenCT 06510United States

Obesity has a multifactorial etiology and is known to be a state of chronic low-grade inflammation,known as *** state is associated with the development of metabolic disorders such as glucose intolerance and nonalcoholic fatty liver *** is a glycolytic metabolite and a crucial node in various metabolic ***,its role and molecular mechanism in obesity and associated complications are *** this study,we reported that pyruvate substantially inhibited adipogenic differentiation in vitro and its administration significantly prevented HFD-induced weight gain,white adipose tissue inflammation,and metabolic *** identify the target proteins of pyruvate,drug affinity responsive target stability was employed with proteomics,cellular thermal shift assay,and isothermal drug response to detect the interactions between pyruvate and its molecular ***,we identified cytosolic phospholipase A2(cPLA2)as a novel molecular target of pyruvate and demonstrated that pyruvate restrained diet-induced obesity,white adipose tissue inflammation,and hepatic steatosis in a cPLA2-dependent *** with global ablation of cPLA2 in mice showed that the protective effects of pyruvate were largely abrogated,confirming the importance of pyruvate/cPLA2 interaction in pyruvate attenuation of inflammation and ***,our study not only establishes pyruvate as an antagonist of cPLA2 signaling and a potential therapeutic option for obesity but it also sheds light on the mechanism of its ***’s prior clinical use indicates that it can be considered a safe and viable alternative for obesity,whether consumed as a dietary supplement or as part of a regular diet.

关键词： metabolic disease pyruvate cytosolic phospholipase obesity

Acceleration of solar wind particles due to inertial alfvén waves

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Communications in Theoretical Physics 2024年第6期76卷 137-141页

作者： Kiran Batool Imran A Khan M Shamir abdul Kabir S Ayaz Theoretical Physics Department National Centre for PhysicsIslamabad 44000Pakistan Department of Space Sciences Institute of Space TechnologyIslamabad 44000Pakistan Space and Astrophysics Research Lab(SARL) National Center of GIS and Space Applications(NCGSA)Islamabad 44000Pakistan Salam Chair Department of PhysicsGC University LahoreKatchery RoadLahorePunjab 54000Pakistan Department of Space Science and CSPAR University of Alabama in HuntsvilleHuntsvilleAL 35899United States of America

Gaining an understanding of the effects and dynamics of the solar wind is crucial for the study of space weather,Earth's magnetosphere,spacecraft protection,the dynamics of the Solar System,and various other *** show that alfvén waves effectively transfer energy to resonant *** study demonstrates how inertial alfvén waves deliver their energy to resonant plasma particles in different solar environments under certain *** analysis shows that inertial alfvén waves experience more rapid damping with increasing parallel wavenumber,ambient magnetic field strength,and particle number density,coupled with a decrease in *** rate of energy transfer to resonant particles intensifies with higher temperatures and reduced parallel wavenumber and particle number *** with higher initial velocities actively participate in Landau damping,especially in regions with a stronger ambient magnetic field.

关键词： solar wind inertial alfven waves resonant particles

On the existence and stability of traversable wormhole solutions with novel shapefunctions in the framework of F(R,L_(m))gravity

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Communications in Theoretical Physics 2024年第5期76卷 114-127页

作者： Sourav Chaudhary Jitendra Kumar S K Maurya Sweeti Kiroriwal abdul Aziz Department of Mathematics Central University of HaryanaJant-PaliMahendergarhIndia Department of Mathematical and Physical Sciences College of Arts and ScienceUniversity of NizwaP.O.Box 33Nizwa 616Oman

In this work,we have explored wormhole(WH)solutions in F(R,L_(m))gravity by assuming the Morris-Thorne WH metric and F(R,Lm)=R/2+(1+γR)L_(m),whereγis the free model *** determined the WH solutions by utilizing two newly developed shape functions(SF)that satisfy all basic conditions for a WH’s physical *** also observe that the null energy condition(NEC)behaves ***,for both models,we use the volume integral quantifier(VIQ)and Tolman-Oppenheimer-Volkoff(TOV)equation to determine how much exotic matter is needed near the WH throat and the stability of the *** extensive detailed discussions of the matter components have been done via graphical *** obtained WH geometries meet the physically acceptable conditions for a stable wormhole.

关键词： energy conditions wormhole exotic matter F(R L_(m))gravity

Fabrication of La,Ce co-doped ZnO nanorods for improving photodegradation of methylene blue

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Journal of Rare Earths 2024年第1期42卷 76-83,I0003页

作者： Erfan Hakim Azmal Zaid Jin-Chung Sin Sze-Mun Lam abdul Rahman Mohamed School of Chemical Engineering Universiti Sains Malaysia(USM)14300Nibong TebalPenangMalaysia College of Environmental Science and Engineering Guilin University of TechnologyGuilin541004China Guangxi Key Laboratory of Theory and Technology for Environmental Pollution Control Guilin University of TechnologyGuilin541004China Collaborative Innovation Center for Water Pollution Control and Water Safety in Karst Area Guilin University of TechnologyGuilin541004China Faculty of Engineering and Green Technology Universiti Tunku Abdul RahmanJalan UniversitiBandar Barat31900KamparPerakMalaysia

La,Ce co-doped ZnO nanorods(ZnLC)were synthesized through a one-step solvothermal *** photocatalysts were characterized by X-ray diffraction,Raman spectroscopy,field-emission scanning electron microscopy,energy dispersive X-ray,transmission electron microscopy,UV-vis diffuse reflectance spectroscopy and photo luminescence *** La and Ce doping enhanced the visible light absorption ability of ZnLC and a red shift was detected for *** simulated solar light irradiation,the ZnO doped with 3 at%La and 1 at%Ce(ZnLC1)degrades methylene blue(MB)more effectively than those of pure ZnO,La-doped ZnO(ZnL)and commercially available *** improved photocatalytic performance of ZnLC1 can be attributed to the high charge separation efficiency as demonstrated by the photoluminescence ***,the photocatalytic experiments reveal that several parameters have their own impact on the MB *** a variety of radical scavengers,it is discovered that superoxide anion radical plays a crucial role in the degradation of *** ZnLC1 is also reused several times without noticeable decrease of photoactivity,indicating that it has a substantial potential for environmental remediation applications.

关键词： ZnO Lanthanum Cerium Co-doping Photodegradation Rare earths