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Salt-Induced Changes in Physio-Biochemical and Antioxidant Defense System in Mustard Genotypes

Phyton-International Journal of Experimental Botany 2020年第3期89卷 541-559页

作者： Md.Shakhawat Hossain Md.Daud Hossain abdul hannan Mirza Hasanuzzaman Md.Motiar Rohman Central Laboratory Research WingBangladesh Agricultural Research InstituteGazipur 1701Bangladesh Seed Technology Division Bangladesh Agricultural Research InstituteGazipur 1701Bangladesh Department of Agronomy Sher-e-Bangla Agricultural UniversityDhaka 1207Bangladesh Molecular Breeding Lab Plant Breeding DivisionBangladesh Agricultural Research InstituteGazipur 1701Bangladesh

Salinity stress is a major factor limiting plant growth and productivity of many crops including *** present study investigated the identification of salt tolerant mustard genotypes and better understanding the mechanism of salinity *** stresses significantly reduced relative water content(RWC),chlorophyll(Chl)content,K^(+) and K^(+)/Na^(+) ratio,photosynthetic rate(P N),tran-spiration rate(Tr),stomatal conductance(gs),intercellular CO_(2) concentration(Ci)and increased the levels of proline(Pro)and lipid peroxidation(MDA)contents,Na+,superoxide(O_(2)^(•−))and hydrogen peroxide(H_(2)O_(2))in both tolerant and sensitive mustard *** tolerant genotypes maintained higher Pro and lower MDA content than the salt sensitive genotypes under stress *** activities of superoxide dismutase(SOD),catalase(CAT),peroxidase(POD),glutathione peroxidase(GPX),monodehydroascorbate reductase(MDHAR)and dehydroascorbate reductase(DHAR)were increased with increasing salinity in salt tolerant genotypes,BJ-1603,BARI Sarisha-11 and BARI Sarisha-16,but the activities were unchanged in salt sensitive genotype,BARI ***,the increment of ascorbate peroxidase(APX)activity was higher in salt sensitive genotype as compared to tolerant ***,the activ-ities of glutathione reductase(GR)and glutathione S-transferase(GST)were increased sharply at stress conditions in tolerant genotypes as compared to sensi-tive *** accumulation of Pro along with improved physiological and biochemical parameters as well as reduced oxidative damage by up-regulation of antioxidant defense system are the mechanisms of salt tolerance in selected mustard genotypes,BJ-1603 and BARI Sarisha-16.

关键词： Mustard saline sensitivity photosynthesis antioxidants ionic imbalance oxidative stress

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Controllable synthesis of a hollow Cr2O3 electrocatalyst for enhanced nitrogen reduction toward ammonia synthesis

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Chinese Journal of Chemical Engineering 2022年第1期35卷 358-365页

作者： Lei Shi Yu Yin Hong Wu Rajan Arjan Kalyan Hirani Xinyuan Xu Jinqiang Zhang Nasir Rafique abdul hannan Asif Shu Zhang Hongqi Sun School of Engineering Edith Cowan UniversityJoondalupWA 6027Australia College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China

As a fascinating alternative to the energy-intensive Haber-Bosch process,the electrochemically-driven N_(2) reduction reaction(NRR)utilizing the N_(2) and H_(2)O for the production of NH3 has received enormous *** development and preparation of promising electrocatalysts are requisite to realize an efficient N_(2) conversion for NH3 *** this research,we propose a template-assisted strategy to construct the hollow electrocatalyst with controllable *** a paradigm,the hollow Cr_(2)O_(3) nanocatalyst with a uniform size(~170 nm),small cavity and ultrathin shell(~15 nm)is successfully fabricated with this *** promising hollow structure is favourable to trap N_(2) into the cavity,provides abundant active sites to accelerate the three-phase interactions,and facilitates the reactant transfer across the *** to these synergetic effects,the designed catalyst displays an outstanding behaviour in N_(2) fixation for NH3 production in ambient *** the neutral electrolyte of 0.1 mol·L^(-1) Na_(2)SO_(4),an impressive electrocatalytic performance with the NH3 generation rate of 2.72μg·h^(-1)·cm^(-2) and a high FE of 5.31%is acquired respectively at-0.85 V with the hollow Cr_(2)O_(3) *** by this work,it is highly expected that this approach could be applied as a universal strategy and extended to fabricating other promising electrocatalysts for realizing highly efficient nitrogen reduction reaction(NRR).

关键词： Hollow structure Electrocatalytic N_(2)fixation NH_(3)synthesis Template-assisted strategy Ambient condition

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Simulation, Modeling, and Optimization of Intelligent Kidney Disease Predication Empowered with Computational Intelligence Approaches

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Computers, Materials & Continua 2021年第5期67卷 1399-1412页

作者： abdul hannan Khan Muhammad Adnan Khan Sagheer Abbas Shahan Yamin Siddiqui Muhammad Aanwar Saeed Majed Alfayad Nouh Sabri Elmitwally School of Computer Sciences National College of Business Administration and EconomicsLahore54000Pakistan Department of Computer Science&IT Minhaj University LahoreLahore54000Pakistan Department of Computer Science Faculty of ComputingRiphah International UniversityLahore CampusLahore54000Pakistan Department of Computer Science Virtual University of PakistanIslamabad45000Pakistan Department of Information Systems College of Computer and Information SciencesJouf UniversitySkakaAljouf72341Saudi Arabia Department of Computer Science College of Computer and Information SciencesJouf UniversitySkakaAljouf72341Saudi Arabia Department of Computer Science Faculty of Computers and Artificial IntelligenceCairo UniversityGiza12613Egypt

Artificial intelligence(AI)is expanding its roots in medical *** acute and chronic diseases can be identified accurately at the initial level by using AI methods to prevent the progression of health *** diseases are producing a high impact on global health and medical practitioners are suggested that the diagnosis at earlier stages is one of the foremost approaches to avert chronic kidney disease and renal *** blood pressure,diabetes mellitus,and glomerulonephritis are the root causes of kidney ***,the present study is proposed a set of multiple techniques such as simulation,modeling,and optimization of intelligent kidney disease prediction(SMOIKD)which is based on computational intelligence ***,seven parameters were used for the fuzzy logic system(FLS),and then twenty-five different attributes of the kidney dataset were used for the artificial neural network(ANN)and deep extreme machine learning(DEML).The expert system was proposed with the assistance of medical *** the quick and accurate evaluation of the proposed system,Matlab version 2019 was *** proposed SMOIKD-FLSANN-DEML expert system has shown 94.16%*** this study concluded that SMOIKD-FLS-ANN-DEML system is effective to accurately diagnose kidney disease at initial levels.

关键词： Fuzzy logic system artificial neural network deep extreme machine learning feed-backward propagation SMOIKD-FLS SMOIKD-ANN SMOIKD-DEML SMOIKD-FLS-ANN-DEML

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Frequency of StaphylococcalCassette Chromosome mecType IV and Type V in Clinical Isolates of Methicillin Resistant Staphylococcus aureus

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Open Journal of Medical Microbiology 2015年第2期5卷 69-75页

作者： abdul hannan Faqeeha Javed Sidrah Saleem Khadija Tahira Shah Jahan Department of Microbiology University of Health sciences Lahore Pakistan

MRSA is able to generate a modified variety of penicillin binding protein named as PBP2a instead of PBP which makes it resistant against penicillin and methicillin. Production of PBP2a is due to the presence of a gene on Staphylococcal cassette chromosome or SCC termed as “mec-A gene”. SCC is a mobile genetic element carrying many resistance genes. It is because of current antibiotic selection pressure that by now there are eight types (I - VIII) of SCCmec. This research has been designed to determine frequency of SCCmec type IV and V in clinical isolates of MRSA. A total of 70 presumptive MRSA isolates collected from a tertiary care hospital of Lahore were cultured on blood agar, incubated overnight at 37°C aerobically. Next day, they were examined for cultural characteristics, colonial morphology, gram stain, and biochemical profile. Confirmation of MRSA was done by phenotypic disk diffusion method according to (CLSI) 2013 guidelines. mecA gene was also detected at molecular level. Molecular identification of SCCmec type IV and V was done by Nested PCR strategy. A total of 50 isolates were confirmed to be MRSA Molecular detection of SCCmec type IV and V revealed that 11 isolates (22%) possess SCCmec type IV and only 2 isolate (4%) carries SCCmec type V. It is obvious from results that SCCmec type IV and V are present in our population too. Larger study (with larger sample size) might be undertaken to find out actual emergence of SCCmec type IV and V in our population.

关键词： MRSA SCCmec Type IV SCCmec Type V

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Cardiometabolic Risk in Overweight and Obese Children in Bangladesh

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Open Journal of Endocrine and Metabolic Diseases 2019年第10期9卷 103-117页

作者： Muhammad abdul hannan Tahniyah Haq Muhammad Abu Hasanat Muhammad Fariduddin Sherpur District Hospital Sherpur Bangladesh Department of Endocrinology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh

Introduction: Childhood obesity is increasing dramatically and represents an important public health issue due to associated metabolic and cardiovascular comorbidities. Very limited data are available regarding cardiometabolic risk factors among this group in Bangladesh. Objective: To observe the cardiometabolic risk factors in overweight and obese children. Methods: This cross-sectional study was carried out in 88 overweight and obese children recruited consecutively by using CDC percentile chart for body mass index (BMI) in children between January 2017 and March 2018 in the Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. After completing a questionnaire and relevant clinical examination, blood was collected for fasting plasma glucose (FPG), insulin, HbA1c, lipid profile and C-reactive protein (CRP). Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) was used to determine insulin resistance. Results: Central obesity (100%), dyslipidaemia (88.6%), raised CRP (81.8%) and metabolic syndrome (69.3%) were the most common cardiometabolic risk factors. Children with grade 3 obesity had significantly higher systolic blood pressure (115.57 ± 11.60 vs 105.71 ± 8.84 mmHg, p = 0.043) and insulin resistance (7.15 ± 4.97 vs 3.53 ± 2.04, p = 0.017) than grade 1 obesity. Blood pressure, insulin resistance and CRP increased while high density lipoprotein (HDL) decreased with increasing severity of obesity. BMI z score was a significant predictor of systolic blood pressure;waist circumference was an independent predictor of diastolic blood pressure and HDL;waist height ratio best predicted insulin resistance, CRP and total cholesterol in overweight/obese children. Conclusions: We have observed a high frequency of cardiometabolic risk factors in overweight and obese children and they increased worsened with increasing grade of obesity.

关键词： Cardiometabolic Risk Overweight Obese

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The antihyperglycemic effect of Bridelia ndellensis ethanol extract and its fractions is mediated by an insulinotropic action

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Journal of Diabetes Mellitus 2013年第3期3卷 111-115页

作者： Selestin Dongmo Sokeng Begum Rokeya Jamadder Mohammed abdul hannan Liaquat Ali Pierre Kamtchouing Department of Biological Sciences University of Ngaoundéré Ngaoundéré Cameroon Department of Pharmacy North South University Dhaka Bangladesh Laboratory of Animal Physiology Faculty of Science University of Yaounde Yaounde Cameroon Research Division Bangladesh Institute of Research and Rehabilitation in Diabetes Endocrine and Metabolic Disorders (BIRDEM) Dhaka Bangladesh

Backgroung: Bridelia ndellensis (Euphorbiaceae) is used as a traditional plant treatment of diabetes. The aim of the present study was to investigate the mechanism involved in the antihyperglycemic effects of this plant. Methods: An intestinal perfusion technique was used to study the effect of the ethanol extract of B. ndellensis on the intestinal absorption of glucose in normal rats fasted for 36 h. The effect of the extract (50 and 100 mg/kg) on Insulin secretion was evaluated using BRIN-BD11 pancreatic cells. Results: In a perfused rat intestinal preparation in situ, the plant extract at a concentration of 5 mg/ml did not show any inhibitory effects on glucose absorption when compared with control animals. Ouabain which is an inhibitor of glucose transport across the small intestine significantly (p < 0.001) decreased the glucose absorption during the whole perfusion period compared with the control group. On the other hand, the plant extract inhibited the gastrointestinal motility induced by Barium sulphate milk in rats. The ethanol extract of B. ndellensis at concentrations of 50 and100mg/ml stimulated in a concentration-dependent manner the insulin secretion from BRIN-BD11 cells in vitro. The induction of insulin release was significantly different when compared to control with the concentration of 100 μg/ml (P < 0.001). Alanine (10 mM) used as positive control, significantly (p < 0.001) stimulated insulin release from BRIN-BD11 cells. Conclusion: The present study has revealed that B. ndellensis ethanol extract stimulates insulin secretion and does not affect the glucose absorption, and it has suggested that the antihyperglycemic effects of B. ndellensis is partly mediated by the stimulation of insulin secretion.

关键词： Bridelia ndellensis Ethanol Extract Intestinal Glucose Absorption Insulin Secretion in Vitro

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Incidence and predictors of hypocalcemia in end-stage renal disease patients on denosumab therapy: A systematic review and metaanalysis

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World Journal of Meta-Analysis 2024年第3期12卷 68-78页

作者： abdul hannan Siddiqui Misbah Shaikh Afia Salman Muhammad Ahmed Ali Fahim Fizzah Batool Tahreem Mari Sarah Musani Muneeb Fareed Rooma Rehan Amna Hassni Urooj Nizami Ayesha Amir abdul Moeed Salim R Surani Department of Internal Medicine Dow University of Health SciencesKarachi 74200SindhPakistan Department of Medicine&Pharmacology Texas A&M UniversityCollege StationTX 77843United States

BACKGROUND Denosumab inhibits the receptor activator of nuclear factor *** markedly increases bone mineral density and has been proven to reduce the risk of ***,numerous adverse effects,notably hypocalcemia,are prevalent in patients with end-stage renal disease(ESRD).AIM To analyze the incidence and predictors of hypocalcemia caused by denosumab compared to control in patients with *** We conducted this study in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses ***,Scopus,Cochrane Central,and EMBASE were systematically searched from inception through March *** original studies investigating the effects of denosumab on patients with ESRD compared to control were *** primary outcomes of our study were the incidence of mild,severe,and very severe *** outcomes included serum levels of intact parathyroid hormone,calcium,and *** results were pooled and analyzed using a random-effects *** Seven articles comprising 3240 patients were included in our *** treated with denosumab had a significantly increased incidence of mild hypocalcemia[risk ratio(RR):2.79;95%confidence interval(CI):0.99-7.91;P=0.05;I^(2)=37%]and of very severe hypocalcemia(RR:9.58;95%CI:1.58-57.98;P=0.01;I^(2)=49%).However,an increase in the occurrence of severe hypocalcemia was non-significant(RR:4.23;95%CI:0.47-38.34;P=0.20;I^(2)=96%).Alternatively,denosumab showed a significant decrease in serum intact parathyroid hormone[mean difference(MD):-433.20,95%CI:-775.12 to-91.28,I2=98%,P=0.01],while there was a non-significant decrease in phosphate(MD:-0.47,95%CI:-1.35 to 0.41,I^(2)=88%,P=0.30)and calcium levels(MD:-0.33,95%CI:-0.95 to 0.29,I^(2)=94%,P=0.29).CONCLUSION Our study demonstrated that denosumab is significantly associated with mild and very severe hypocalcemia in patients with ESRD making it necessary to detect and prevent this side effect of treatmen

关键词： Denosumab End-stage renal disease Hypocalcemia Parathyroid hormone Dialysis

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具有勢壘的Sturm-Liouville算子的特徵值和特徵函數

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Chinese Quarterly Journal of Mathematics 2023年第1期38卷 50-61页

作者： SARWAR Qanitah 黄振友 ZAHID abdul hannan XU Xin-Jian Department of Applied Mathematics Nanjing University of Science and TechnologyNanjing 210094China Department of Chemical Engineering University of GujratGujrat 50700Pakistan Key Laboratory for Soft Chemistry and Functional Materials Ministry of EducationNanjing University of Science and TechnologyNanjing 210094China

We aim to find the eigenvalues and eigenfunctions of the barrier potential case for Strum-Liouville operator on the finite interval [0,π] when λ > 0. Generally, the eigenvalue problem for the Sturm-Liouville operator is often solved by using integral equations, which are sometimes complex to solve, and difficulties may arise in computing the boundary values. Considering the said complexity, we have successfully developed a technique to give the asymptotic formulae of the eigenvalue and the eigenfunction for Sturm-Liouville operator with barrier potential. The results are of significant interest in the field of quantum mechanics and atomic systems to observe discrete energy levels.

关键词： Sturm-Liouville operator Eigenvalue Eigenfunction Barrier potential Asymptotic estimate

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Demographic, Clinical and Biochemical Characteristics of Drug Naive Type 2 Diabetes Patients of Bangladesh

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Open Journal of Endocrine and Metabolic Diseases 2021年第8期11卷 145-154页

作者： Shahjada Selim Masud-Un Nabi Mohammad Saifuddin Mohammad abdul hannan Muhammed Abu Bakar Samir Kumar Talukder A. B. M. Kamrul Hasan Mohammad Nurul Amin Md. Azizul Hoque Md. Shahinur Rahman Ahmed Salam Mir Faria Afsana Department of Endocrinology Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Department of Endocrinology Rajshahi Medical College Rajshahi Bangladesh Diabetes & Endocrinology Dhaka Medical College Dhaka Bangladesh Department of Endocrinology North East Medical College & Hospital Sylhet Bangladesh Department of Endocrinology Chattogram Maa O Shishu Hospital Chattogram Bangladesh Department of Endocrinology Rangpur Medical College Rangpur Bangladesh Department of Endocrinology Mymensingh Medical College Mymensingh Bangladesh Department of Endocrinology Mugda Medical College Dhaka Bangladesh Endocrinology Shaheed Ziaur Rahman Medical College Bogura Bangladesh Department of Diabetes and Endocrinology Pabna Diabetic Association Hospital Pabna Bangladesh Department of Endocrinology Bangladesh Institute of Health Sciences Dhaka Bangladesh Department of Endocrinology BIRDEM Dhaka Bangladesh

Background: Although the frequencies of getting drug naive type 2 diabetes patients among all the diabetic patients are very low, nowadays it claims more attention in the treatment procedures of drug naive diabetic patients. But in Bangladesh, we have very few research-oriented data regarding the demographic, clinical and biochemical characteristics of drug naive type 2 diabetes patients. The aim of this study was to determine the demographic clinical and biochemical characteristics of drug naive type 2 diabetes patients of Bangladesh. Methods: This was an open label observational real-life study which was conducted in the chambers of the investigators in several places of Bangladesh as outdoor setting during the period from August 2020 to December 2020. In total, 250 patients with drug naive type 2 diabetes mellitus were enrolled as the study population. Proper written consents were taken from all the participants before starting data collection. A pre-designed questionnaire was used in patient data collection. All data were processed, analyzed and disseminated by MS Office and SPSS version as per need. Result: Two hundred and fifty (250) participants were selected as study population. The male-female ratio of the participants was 1.4:1. The highest number of participants was from 51 - 60 years’ age group (31.20%). The highest number of participants (41%) was with overweight (BMI: 25 - 30 kg/m2). Majority (65%) of the patients of this study suffered from diabetes for ≤5 years. The mean (±SD) SBP of the participants was 137.25 ± 17.50 mmHg and the mean (±SD) DBP of the participants was 85.16 ± 13.39 mmHg. We found the mean (±SD) fasting blood sugar (mg/dl), post prandial blood sugar (mg/dl), total cholesterol (mg/dl), triglycerides (mg/dl), HDL-Cholesterol (mg/dl), LDL-cholesterol (mg/dl), VLDL-cholesterol (mg/dl), uric acid (mg/dl), creatinine (mg/dl), urea (mg/dl), total bilirubin (mg/dl), direct biliru

关键词： Demographic Biochemical Clinical Characteristics Drug Naive Type 2 Diabetes Bangladesh

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Processed Radio Frequency towards Pancreas Enhancing the Deadly Diabetes Worldwide

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Journal of Endocrinology Research 2021年第1期3卷 1-20页

作者： Md.Rahimullah Miah Mohammad abdul hannan AAM Shazzadur Rahman Md.Shahariar Khan Md Mokbul Hossain Ishrat Tasnim Rahman Md.Sabbir Hossain Chowdhury Shadman Shahriar Mohammad Basir Uddin Mohammad Taimur Hossain Talukdar Mohammad Shamsul Alam S.A.M.Imran Hossain Alamgir Adil Samdany Shahriar Hussain Chowdhury Alexander Kiew Sayok Department of Health Information Technology Northeast Medical Pvt.LimitedSylhetBangladesh. Department of Endocrinology North East Medical College&HospitalSylhetBangladesh. Department of Medicine North East Medical CollegeSylhetBangladesh. Department of Paediatrics North East Medical College&HospitalSylhetBangladesh. Department of Pharmacology North East Medical College and HospitalSylhetBangladesh. Ananda Niketan SylhetBangladesh. Department of Pathology North East Medical College and HospitalSylhetBangladesh. USA and Ex-student of North East Medical College SylhetBangladesh. Department of Paediatrics North East Medical College and HospitalSylhetBangladesh Department of Clinical Oncology North East Medical College and HospitalSylhetBangladesh. Department of Forensic Medicine North East Medical College and HospitalSylhetBangladesh. Department of Oral and Maxillofacial Surgery North East Medical CollegeSylhetBangladesh. Department of Orthopedics North East Medical CollegeSylhetBangladesh. Department of Dermatology North East Medical CollegeSylhetBangladesh. IBEC University Malaysia SarawakKota SamarahanSarawakMalaysia.

Diabetes is a chronic and debilitating disease,which is associated with a range of complications putting tremendous burden on medical,economic and socio-technological infrastructure *** the higher authorities of health services are facing the excruciating cumulative reasons of diabetes as a very imperative worldwide issue in the 21st *** study aims to relook at the misapplication of the processed radio frequency that frailties in the pancreas within and around the personal body boundary *** administered sensor data were obtained at laboratory experiments from the selected specimens on dogs and cats in light and dark *** study shows the frequent urine flow speed varies with sudden infection due to treated wireless sensor networks in active open *** overweight and obese persons are increasingly affected in diabetes with comprehensive urinary pressure due to continuous staying at dark *** findings replicate the increasing tide of diabetes *** study also represents the difficulties of physicians to provide adequate diabetic management according to their expectancy due to insecure personal area network control *** sensor network is indispensable for healthcare but such network is at risk to health security due to digitalized poisoning within GPS *** study recommends the anti-radiation integrated system policy with user’s security alternative approach to inspire dealing with National Health Policy and Sustainable Development Goals 2030.

关键词： Diabetes Radio frequency Pancreas Active open eyes Body boundary Network security

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