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Effect of quarry dust addition on the performance of controlled low-strength material made from industrial waste incineration bottom ash

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International Journal of Minerals,Metallurgy and Materials 2012年第6期19卷 536-541页

作者： Naganathan Sivakumar abdul Razak Hashim abdul hamid siti nadzriah Department of Civil Engineering University of MalayaKuala Lumpur 50603Malaysia Kualiti Alam Sendirian Berhad Port Dickson 71000Malaysia

The performance of industrial waste incineration bottom ash in controlled low-strength material （CLSM） was investigated in this paper, as the quarry dust was added. CLSM mixtures were made from the industrial waste incineration bottom ash, quarry dust, and cement. Tests for fresh density, bleeding, compressive strength, shear strength, hydraulic conductivity, and excavatability were carried out. The com- pressive strength ranges from 60 kPa to 6790 kPa, the friction angle varies from 5°to 19°, and the cohesion is from 4 to 604 kPa. Most of the mixtures are found to be non-excavatable. It is indicated that the quarry dust addition increases the compressive strength and shear parame- ters, decreases bleeding, and increases the removability modulus.

关键词： industrial waste treatment waste incineration ashes quarries dust hydraulic conductivity strength of materials

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Nephroprotective effects of Zingiber zerumbet Smith ethyl acetate extract against paracetamol-induced nephrotoxicity and oxidative stress in rats

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第3期13卷 176-185页

作者： Zariyantey abdul hamid siti Balkis BUDIN Ng WEN JIE Asmah hamid Khairana HUSAIN Jamaludin MOHAMED Department of Biomedical Science Faculty of Health Sciences Universiti Kebangsaan Malaysia Jalan Raja Muda Abdul Aziz 50300 Kuala Lumpur Malaysia Drug and Herbal Research Center Faculty of Pharmacy Universiti Kebangsaan Malaysia Jalan Raja Muda Abdul Aziz 50300 Kuala Lumpur Malaysia

Paracetamol (PCM) overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms mediating the event. In this study, the effects of ethyl acetate extract of Zingiber zerumbet rhizome [200 mg per kg of body weight (mg/kg) and 400 mg/kg] on PCM-induced nephrotoxicity were examined. Rats were divided into five groups containing 10 rats each. The control group received distilled water while other groups were treated with extract alone (400 mg/kg), PCM alone (750 mg/kg), 750 mg/kg PCM+200 mg/kg extract (PCM+ 200-extract), and 750 mg/kg PCM+400 mg/kg extract (PCM+400-extract), respectively, for seven consecutive days. The Z. zerumbet extract was given intraperitoneally concurrent with oral administration of PCM. Treatment with Z. zerumbet extract at doses of 200 and 400 mg/kg prevented the PCM-induced nephrotoxicity and oxidative impairments of the kidney, as evidenced by a significantly reduced (P<0.05) level of plasma creatinine, plasma and renal malondialdehyde (MDA), plasma protein carbonyl, and renal advanced oxidation protein product (AOPP). Furthermore, both doses were also able to induce a significant increment (P<0.05) of plasma and renal levels of glutathione (GSH) and plasma superoxide dismutase (SOD) activity. The nephroprotective effects of Z. zerumbet extract were confirmed by a reduced intensity of renal cellular damage, as evidenced by histological findings. Moreover, Z. zerumbet extract administered at 400 mg/kg was found to show greater protective effects than that at 200 mg/kg. In conclusion, ethyl acetate extract of Z. zerumbet rhizome has a protective role against PCM-induced nephrotoxicity and the process is probably mediated through its antioxidant properties.

关键词： Zingiber zerumbet Antioxidant Oxidative stress Nephrotoxicity Paracetamol

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Antioxidant Properties and Glucan Compositions of Various Crude Extract from <i>Lentinus squarrosulus</i>Mycelial Culture

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Advances in Bioscience and Biotechnology 2014年第10期5卷 805-814页

作者： Rahayu Ahmad Sutha Muniandy Nur Iffah abdullah Shukri siti Mariatul Usyida Alias Aidil abdul hamid Wan Mohtar Wan Yusoff Sahidan Senafi Fauzi Daud School of Bioscience and Biotechnology Faculty Science and Technology National University of Malaysia Bangi Malaysia

Various crude extracts of Lentinus squarrosulus mushroom mycelium and culture broth were prepared for antioxidant studies, glucan and carbohydrate compound analysis. Crude extract from ethanol, cold and hot water extraction was tested on several complementary test systems namely DPPH free radical scavenging, β-carotene linoleic acid oxidation, total phenolic compound, total flavonoid compound, total carbohydrate content and total glucan compositions. The antioxidant activity of the crude extracts of Lentinus squarrosulus mushroom mycelium and culture broth was determined by 2,2’ diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method and β-carotene linoleic acid assay. Crude extracted from culture broth EPS EE recorded the highest radical scavenging effects at 20 mg/mL (85%) which is closer to the control antioxidants (ascorbic acid 97%;BHT 92.4%;BHA 93.6%). Both the ethanol extract (IPS EE and EPS EE) exhibited the highest β-carotene linoleic acid oxidation by recording IC50 values of 0.6 and 0.65 mg/mL respectively. IPS EE (0.59 mg/g) and EPS WE (0.58 mg/g) showed high flavonoid content whereas total phenol content was high in EPS WE (0.85 mg/g) and IPS EE (0.84 mg/g). Total carbohydrate concentrations were high in IPS HWE and IPS CWE with 19.1 and 16.3 mg/mL respectively and these data correlate with the β-glucan content in both extracts. The highest β-glucan content found in IPS CWE and IPS HWE were 12.2 and 11.4% w/w respectively.

关键词： Lentinus squarrosulus β-Glucan Antioxidant Polysaccharides Submerged Fermentation

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