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Ambulatory Radio Iodine Therapy in the Management of Hyperthyroidism in Africa: African Systematic Review and Perspectives in Burkina Faso

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Open Journal of Biophysics 2024年第1期14卷 1-10页

作者： ki Thierry Romuald Mamadou Salif Djigo Gora Thiaw Arsène sanou Mamounata Zoungrana Mamadou Mbodj Nuclear Medicine Department of the Yalgado OUEDRAOGO University Hospital Center in Ouagadougou Ouagadougou Burkina Faso Biophysics and Nuclear Medicine Laboratory of the Cheikh Anta DIOP University of Dakar Dakar Senegal Radiology Departement of the Bobo Dioulasso University Hospital Center in Bobo Dioulasso Bobo Dioulasso Burkina Faso

Introduction: In hyperthyroidism, selective irradiation of the thyroid gland with radioactive iodine is a radical treatment and an alternative to surgery. The aim of this review is to assess the medium-term efficacy of outpatient treatment of hyperthyroidism with iodine-131 in Africa. Methods: We identified the studies carried out in Africa on outpatient radiation therapy between 2016 and 2020. For each article included, we noted the country concerned and the year of publication, the numbers studied, the socio-demographic characteristics of the patients, the indications for radio iodine therapy, the dose administered, the results of the hormonal dosage 6 months after radiation. Results: 13 retrospective studies were included to constitute a total population of 925 patients. The average age was 40.77 years, the sex ratio of 1/5.4 with a clear female predominance. The 3 main etiologies of hyperthyroidism justifying outpatient radio iodine therapy were Graves’ disease (55.89%), toxic multinodular goiter (22.70%) and toxic adenoma (21.40%). The average dose of iodine 131 administered per course is 13.7 mCi. No short-and medium-term complications were reported. The radio iodine therapy was effective in 86.08% (n = 796) of the patients with extremes of 72% and 100%. Conclusion: Radio iodine therapy is effective in Africa. It is simple, inexpensive on an outpatient basis and well tolerated. The introduction of outpatient radio iodine therapy could improve the management of patients with hyperthyroidism in Burkina Faso.

关键词： Hyperthyroidism Outpatient Radio Iodine Therapy Africa

Detection of Adenovirus in Fresh Fruit, Vegetables, Wastewater and Manure from Irrigated Farms in Ouagadougou, Burkina Faso

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Food and Nutrition Sciences 2024年第7期15卷 644-662页

作者： kuan abdoulaye Traore Madou sanou Jean Bienvenue Ouoba Bruno Lalidia Ouoba Pierre Roques Nicolas Barro Laboratoire de Biologie Molculaire dEpidmiologie et de Surveillance des Bactries et Virus Transmissibles par les Aliments (LaBESTA) Universit Joseph KI-ZERBO Ouagadougou Burkina Faso Laboratoire Sciences de la Vie et de la Terre (LaSVT) Universit Norbert ZONGO Koudougou Burkina Faso Virology Unit Institut Pasteur de Guine Conakry Guinea

Enteric viral pathogens are responsible for numerous epidemics associated with the consumption of fresh fruit and vegetable, whether raw or minimally processed. The aim of the present study was to assess agricultural practices and the presence of adenovirus (AdV) in fruits and vegetables, manure and irrigation wastewater sampled in the urban and peri-urban perimeters of Ouagadougou. A total of 286 samples including 30 lettuces, 42 tomatoes, 30 carrots, 30 strawberries, 74 manures and 80 wastewater samples were collected from four market garden sites in and around Ouagadougou. Nested PCR was performed with specific primers to detect adenoviruses (AdVs). A face-to-face survey was carried out using a questionnaire on market garden production practices. Overall, adenoviruses prevalence was 5.9% [IC95, 3.2% - 8.7%] in all samples analyzed. It was specifically 7.14% (3/42) from tomatoes, 6.7% (2/30) from lettuces, 20% (6/30) on strawberries and 7.5% (6/80) in irrigation water. The survey showed that irrigation water came from untreated sources (dam, well, canal) and then 52% of farms used untreated manure. No farms have implemented measures to limit access by domestic and wild animals. This work shows the presence of human adenoviruses in surface irrigation water and fresh produce, which is of concern when fresh produce is consumed raw. To reduce the public health risks associated with consuming these foods, it is essential to follow good hygiene and cultivation practices.

关键词： Adenovirus Raw Fruits and Vegetables Nested PCR Wastewater Manure Ouagadougou

Management of Square Carcinoma of the Lower Lip Using Camille-Bernard Flap under Local Anesthesia: When Constraints Dictate Our Attitude

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Open Journal of Stomatology 2024年第4期14卷 191-197页

作者： Silly Toure Mouhamadou Makhtar Ndiaye Abibou Ndiaye Mame sanou Diouf Birame Loum Baye karim Diallo Department of Maxillofacial Surgery and Stomatology CHU Aristide Le Dantec of Dakar Dakar Senegal ENT Department Fann University Hospital Dakar Senegal

Introduction: Squamous cell carcinomas of the lip essentially pose a therapeutic management problem. In the West, their treatment is done under general anesthesia and follows the classic rules of oncology. In our context of exercise, we sometimes have a different attitude dictated by various constraints. Observation: 55-year-old patient with no notable history, seen in consultation for a very large ulcerative-budding lesion on the right 2/3 of the lower lip with mucocutaneous involvement without lymph node findings found on examination. Faced with this suspicious lesion and the patient’s financial difficulties, we decided to operate under local anesthesia to remove this tumor. The oncological excision was followed by immediate plasty using a Camille-Bernard flap with a good immediate aesthetic and functional result and postoperative day 7. The patient was unable to take his surgical specimen to anatomy-pathology and was lost to follow-up due to lack of financial resources. On anatomo-pathological analysis of the surgical specimen, the margins were healthy with confirmation of squamous cell carcinoma (anapathological reading made for scientific interest). Discussion: The particular mentality of certain patients and their difficult financial conditions push us to have an unconventional therapeutic attitude in oncology, but which nevertheless makes it possible to resolve certain problems that we often face. Local anesthesia is possible and realistic in cases like ours and the results can be acceptable and life-saving.

关键词： Squamous Cell Carcinoma Lower Lip Camille Bernard Flap Local Anesthesia

Effect of Size and Initial Water Content on the Effective Diffusion Coefficient during Convective Drying of Sweet Potato Cut into Cubic and Cylindrical Shapes

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Journal of Materials Science and Chemical Engineering 2024年第6期12卷 71-82页

作者： Ibrango abdoul Salam Ouoba kondia Honoré Bama Désiré Traoré Yssa Zongo karim Ouedraogo Salifou Laboratoire de Matriaux de lHliophysique et Environnement (La.M.H.E.) Unit de Formation et de Recherche en Sciences. Exactes et Appliques (UFR/SEA) Universit Nazi BONI de Bobo-Dioulasso Bobo-Dioulasso Burkina Faso

In this article, we investigated the influence of size and initial water content on the effective diffusion coefficient of sweet potatoes samples cut into cubic and cylindrical shapes. The sizes of the cubic samples are 0.5, 1, 1.5, 1.75, 2, 2.5 and 3 cm edge with a respective initial water content of 2.7, 3.76, 3.48, 2.68, 3.28, 2.17 and 2.29 kg/kgms. For cylindrical samples, the radius is set at 0.5 cm and sample heights are 1, 1.5, 2, 2.5, 3, 3.5 and 4 cm with respective water contents of 2.2, 3.19, 2.85, 2.1, 2.17, 2.39 and 2.03 kg/kgms. The effective diffusion coefficients of cubic samples are of the order of 10−10 and 10−9 m2∙s−1 grew with sample edge. As for the cylindrical samples, the effective diffusion coefficients were of the order of 10−9 m2∙s−1 and there was no linear correlation between cylinder height and their effective diffusion coefficient. As for the examination of the initial water content on the effective diffusion coefficient, it turned out that the initial water content had no influence on the effective diffusion coefficient of the sweet potato samples.

关键词： Effective Diffusion Coefficient Initial Water Content Sweet Potato Cubic Cylindrical

Alternative Phenotypic Profile for B-Cell Abnormality in a Case at Zinder National Hospital

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Open Journal of Blood Diseases 2024年第1期14卷 8-16页

作者： Brah Moustapha Maman Amadou Djibrilla-Almoustapha Moustapha Elhadji-Chefou abdoul-Aziz Garba Badé Malam-Abdou Department of Medicine Université André Salifou de Zinder Zinder Niger Department of Medicine H&#244pital National de Zinder Zinder Niger Department of Medicine Université Abdou Moumouni de Niamey Niamey Niger Department of Medicine Université Dan Dicko Dan Koulodo de Maradi Maradi Niger

Introduction: Since it is impossible to establish a diagnosis in the presence of hyperlymphocytosis not secondary to lymphocytic hyperactivation, we considered a B-lymphoid hematopathy with a non-specific phenotypic profile. We report one case of this. Observation: This is a forty-eight (48) year old patient with hyperlymphocytosis at 139,000 elements per cubic millimeter, heterogeneous splenomegaly at 25.6 cm in diameter on abdominal ultrasound without detectable deep or peripheral lymphadenopathy. Peripheral blood cytology shows lymphocyte cell proliferation suggestive of the circulating phase of chronic lymphoproliferative B syndrome. The expression profile of cell membrane markers did not allow for the definition of a specific phenotypic profile. Faced with this immunophenotyping result, we considered a B-lymphoid hemopathy with a non-specific phenotypic profile. After three courses, the MINICHOP treatment was used to achieve partial remission with wasting of more than 80% of the evaluable masses. Conclusion: Despite the contribution of immunophenotyping in the diagnosis of lymphoproliferative syndromes, it is possible to consider the diagnosis of a B-lymphoid hemopathy with a phenotypic non-specific profile of CD45+, monotypic kappa, CD19+, FMC7+, CD22+, CD5−, CD79b−, CD23−, CD43−, CD38−, CD200−.

关键词： Hyperlymphocytosis CLL Immunophenotyping MINICHOP

When the Combination of a Chinese Flap and Dufourmentel Makes It Possible to Treat a Hopeless Case of Squamous Cell Carcinoma of the Upper Lip

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Open Journal of Stomatology 2024年第7期14卷 327-335页

作者： Silly Toure Abibou Ndiaye Mouhamadou Makhtar Ndiaye Mamadou Coume Mame sanou Diouf Baye karim Diallo Department of Maxillofacial Surgery and Stomatology CHU Aristide Le DANTEC Dakar Senegal Geriatrics Department CHU AT LE DANTEC Dakar Senegal Otorhinolaryngology and Head and Neck Surgery Department FANN University Hospital Dakar Senegal

Cancers of the lip are the leading cause of labial defects, and treatment is essentially surgical. The success of a repair is assessed by two essential criteria: The functional character of the lip (restoration of continence allowing feeding) and the aesthetic quality of the repair. However, for many patients from countries whose medical infrastructure does not allow them to undertake complex reconstructions locally, medical transfers represent their only chance of treatment. The aim of this article is to share with you an extreme clinical case of labial reconstruction, the management of which was a real challenge, using two major flaps: the free ante-brachial flap and the DUFOURMENTEL-type bi-pediculated scalp flap.

关键词： Surgical Flap Reconstruction Aesthetic Lip Cancer-Plastic Surgery

Exoscopy of Detrital Zircons from Niamey Neoproterozoic Sandstones (Eastern Edge of the West African Craton, Southwestern Niger): Interpretation of Detrital Sediments Provenance

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Open Journal of Geology 2024年第5期14卷 617-628页

作者： Hassan Ibrahim Maharou karimou Laouali Idi Diafarou Alzouma Amadou Salissou abdoul Ganiou Amadou Gnissa Sidibé Moussa konaté Department of Geology Faculty of Science and Techniques Abdou Moumouni University Niamey Niger Department of Life and Earth Sciences Ecole Normale Sup&#233rieure (ENS) Abdou Moumouni University Niamey Niger

This study focuses on exoscopic analyses of detrital zircon grains of Archean and Paleoproterozoic age, contained in the sediments from the Niamey Neoproterozoic sandstones (Niamey region), with a view to confirming the sediments sources already proposed (kénéma-Man domain for Archean-age zircons and Baoulé Mossi domain for Paleoproterozoic-age zircons). Exoscopic analysis reveals that Archean zircon grains are more corroded, with rounded to sub-rounded shapes, while Paleoproterozoic zircon grains are less corroded and mostly angular in shape. The strong corrosion of Archean zircon grains, implying long-distance transport, is consistent with the remoteness of the kenema-Man domain which are the source these sediments. The fact that the Paleoproterozoic zircon grains show little or no wear implies a proximal source of sediments, corresponding to the Baoulé Mossi domain.

关键词： Exoscopic Analysis Detrial Zircon Grains U-Pb Ages Niamey Neoproterozoic Sandstones Niamey Region

Local Criteria Used by Farmers to Evaluate the Agronomic Performance and the Fertilizing Capacity of Cowpea Varieties: Diversity, Variability and Proximal Relation with Agronomic Measurements in Contrasted Sahelian Locations

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Agricultural Sciences 2024年第1期15卷 114-131页

作者： Nouhou Salifou Jangorzo abdoul-Aziz Saïdou Abou-Soufianou Sadda abdoulaye Moussa Mamoudou Hassane Bil-Assanou Issoufou Département des Sciences du Sol et Télédétection Université Dan Dicko Dankoulodo de Maradi Maradi Niger. Unité Mixte de Recherche “Diversité et Adaptation des Plantes” (UMR DAP) Université Dan Dicko Dankoulodo de Maradi Maradi Niger Centre Imaan de Support en Recherche Transdisciplinaire (Imaan Research) Niamey Niger Institut de Recherche pour le Développement Niamey Niger Université Boubacar BA de Tillabéri Tillabéri Niger Département des Sciences et Techniques de Productions Végétales Université Dan Dicko Dankoulodo de Maradi Maradi Niger

When contributing to participatory research, farmers usually appreciate the performance of cowpea varieties using qualitative scores. The score they attribute to each variety are based on local knowledge. The specific criteria they individually use to attribute a score are not well described. The objectives of this work were to: 1) identify and describe exhaustively the local criteria used by farmers to measure the agronomic performance of cowpea;2) assess the variability and statistical structure of these farmer criteria across local contexts;3) and analyze the association between these farmer criteria and the classical agronomic measurement. To achieve these objectives, an augmented block design was implemented across fifteen locations in the regions of Maradi, Dosso and Tillabéri, representing a diversity of local contexts. From a set of 36 cowpea varieties, fifteen varieties were sown per location, including five varieties (controls) common to all locations. In each location, two replicates were sown in randomized Fisher’s blocks. After agronomic measurement and participatory evaluation (scoring of varieties by farmers), a group survey (focus group) was conducted in each location to identify the criteria considered by farmers to found their discretional scoring of varieties during the participatory evaluation. The analysis of the data identified, across locations, thirteen criteria defined by farmers to characterize the agronomic performance of cowpea. Some of these criteria were different according to location. Farmers ranked the three varieties with the best performance for each agronomical trait (Top 3 varieties). A comparison of the farmer ranking with the ranking based on agronomic measurements revealed similarity and complementary between both methods. This study highlighted the importance of considering both local and scientific knowledge in local varietal evaluations.

关键词： Agronomic Performance Participatory Research Cowpea Farmers’ Criteria

Aqueous-phase reforming of hydroxyacetone solution to bio-based H_(2)over supported Pt catalysts

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Green Energy & Environment 2024年第4期9卷 777-788页

作者： A.k.k.Vikla k.koichumanova Songbo He k.Seshan Joint International Research Laboratory of Circular Carbon Nanjing Tech UniversityNanjing211816China Faculty of Science and Technology University of Twente7500 AE EnschedeThe Netherlands CoRe Pro 9723 BL GroningenThe Netherlands

Aqueous-phase reforming(APR)is an attractive process to produce bio-based hydrogen from waste biomass streams,during which the catalyst stability is often challenged due to the harsh reaction *** this work,three Pt-based catalysts supported on C,AlO(OH),and ZrO_(2)were investigated for the APR of hydroxyacetone solution in afixed bed reactor at 225℃and 35 *** them,the Pt/C catalyst showed the highest turnover frequency for H_(2)production(TOF of 8.9 molH_(2)molPt^(-1)min^(-1))and the longest catalyst *** the AlO(OH)and ZrO_(2)supported Pt catalysts,the side reactions consuming H_(2),formation of coke,and Pt sintering result in a low H_(2)production and the fast catalyst *** proposed reaction pathways suggest that a promising APR catalyst should reform all oxygenates in the aqueous phase,minimize the hydrogenation of the oxygenates,maximize the WGS reaction,and inhibit the condensation and coking reactions for maximizing the hydrogen yield and a stable catalytic performance.

关键词： APR Hydroxyacetone TOF Bio-based H_(2) Support effect