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Study of the Geothermal Potential of the Locality of Kaladi and Its Surroundings (Adamawa-Cameroon) from the Frequency Processing of Magnetic Data

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International Journal of Geosciences 2022年第11期13卷 1024-1039页

作者： Ndam Njikam Mohamed Moustapha Meying Arsène Zanga Amougou Alain abdou raouf Nkemndem Agendia Demianus School of Geology and Mining Engineering University of Ngaoundere Ngaoundere Cameroon Department of Physics Faculty of Sciences University of Douala Douala Cameroon Research Center for Deep Ocean Science and Underwater Engineering School of Resources and Geosciences China University of Mining and Technology (CUMT) Xuzhou China Department of Geography University of Buea Buea Cameroon

The aim of this study is to estimate the variations in curie point depth, geothermal gradient and heat flux from the frequency analysis of magnetic data in order to evaluate the geothermal potential of the Kaladi locality and its surroundings. For this purpose, the magnetic field map was first reduced to equator (RTE). The centroid method was used to divide the RTE grid into a set of 40 blocks. The spectral analysis applied to each block allowed determining the depth to top (Zt), center (Z0) and bottom (Zb also called curie point depth or CPD) of the magnetic sources. Knowing the different CPD, the geothermal gradient associated with each block was calculated. The heat flow was then calculated from the geothermal gradient associated with the anomaly block considered. From the set of values obtained for each block, maps of geothermal gradient and heat flow variations were established. Analysis of these maps shows that the sectors that could be favourable for geothermal exploration are the north of Kaladi and the Goro-Bembara corridor, because they show variations in the geothermal gradient and heat flow between 0.4 and 0.8℃/m and between 1.2 and 2 mW/m2 respectively. In addition, the superposition of the different hot springs highlighted in previous studies with areas of high geothermal gradient and heat flow values supports this analysis. The proposed models can be used as background documents for any geothermal exploration project in the study area.

关键词： Spectral Analysis Curie Point Depth Heat Flow Geothermal Gradient

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Management and Evolution of Multiple Myeloma with Renal Failure in Developing Countries: The Case of the Sylvanus Olympio University Hospital in Lome, Togo

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Open Journal of Nephrology 2022年第4期12卷 441-450页

作者： Kossi Akomola Sabi Eyram Fianyo Yoan Makafui Amekoudi Viwale Koffi Tessio Laune Odilon Blatome Badomta Dolaama Ayodélé Jonathan Sabi abdou-raouf Sibabi Zamarou Tchablinam Naleta Owonayo Oniakitan Nephrology Hemodialysis Department of CHU Sylvanus Olympio University of Lomé Lomé Togo Rheumatology Department of The Secondary Hospital of Bè University of Lomé Lomé Togo Nephrology Department of CHU Kara University of Kara Kara Togo Rheumatology Department of CHU Sylvanus Olympio University of Lomé Lomé Togo

Background: Renal failure (RF) is a frequent complication during multiple myeloma (MM) and sometimes reveals the disease. The median survival of MM patients with RF is shorter than that of patients with myeloma without renal involvement. Although patient survival has been prolonged with the new therapies, the median survival does not exceed five to seven years. Few data on this subject are available in sub-Saharan Africa. Objectives: To describe the therapeutic management and evolution of MM with RF in a developing country like Togo. Method: This was a retrospective descriptive and analytical study which took place over a period of ten years (2010-2019) and included the records of patients with MM according to the 2009 and/or 2014 IMWG criteria, hospitalized or followed up in the nephrology and rheumatology departments of the CHU-SO with a GFR Results: During the study period, 78 patients with MM had renal failure (55.7%). Therapeutically, hygienic and dietary measures were dictated in 84.6% of cases (68 patients). Rehydration was performed in 38 cases (48.7%);alkalinization of urine in 10 cases (12.8%);use of antibiotics in 36 cases (46.2%), NSAIDs in 51 cases (65.4%);use of biphosphonates in 36 cases (46.6%). Surgical immobilization by screw-plate osteosynthesis was performed in 02 patients. Nephrologically, 8 patients underwent ESRD. The different chemotherapy protocols used were Melphalan-Prednisone in 70% of cases, Melphalan-Cyclophosphamide-Prednisone in 26.7% of cases and Cyclophosphamide-Prednisone in 3.3%. The median overall survival was 8 months. The median survival was 13 months in patients who recovered from renal failure versus 2 months in those who did not recover from renal failure (p = 0.0030). Of the 78 patients in our series, 22 patients had died (28.2%). Conclusion: Despite renal failure, the Alexanian protocol and biphosphonates are still widely used in combination with symptomatic treatment with significant results.

关键词： Renal Failure Multiple Myeloma Management Evolution Togo

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Chromosomal aberrations and nucleic acids systems affected by some Egyptian medicinal plants used in treating female pregnant diabetic rats

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American Journal of Molecular Biology 2011年第1期1卷 26-32页

作者： Halima S . abdou Sherifa H. Salah Amira Abd El raouf E.A. Abdel-Rahim Dep. Biochem. Fac. Agric. Cairo. University Department of cell biology National Research Center Dokki Egypt

The influences of medicinal plants Juniperus Phoenicea (Araar), Hyphaene thebaica (Doum), An-astatica hierochuntica (Kafta) and Cleome droserifolia (Sammo) as antidiabetic agents were investigated using female pregnant albino rats. Female rats were injected with 60 mg/kg b.w. alloxan to induce diabe-tes. Diabetic rats treated orally with the methanol extracts of tested plants till the 19 day of gestation. The present studies include the frequencies of chro-mosomal aberrations and nucleic acid system of liver in the female pregnant rats and their embryos. The results showed that injection of alloxan caused highly significant increase in chromosomal aberrations as well as in blood glucose levels as a result of diabetes in pregnant females. It also caused a high incidence of chromosomal deviation in embryos and decreased the liver soluble protein contents of female rats and their embryos. These effects in alloxanized animals were treated and improved by ingestion of the methanol extracts of the tested plants (Araar, Doum, Kafta and Somma) in which under their treatments, the inceased level of blood glu-cose of diabetic rats was deceased. Ingestion with the plants methanolic extracts improved and normalized the effects of diabetes in nucleic acids values of liver tissues. These were accompanied with nucleases (RNAase and DNAase) activities. The inhibited ac-tivities of both DNA ase and RNA ase of pregnant rats and their embryos were stimulated and read-justed around the normal values. Also administration of the plants methanol extracts decreased the per-centage of chromosomal aberrations in the female rats and embryos. It is concluded that there are some biochemical dynamics which might occur in the metabo-lism of glucose, nucleic acids and proteins in order to prevent or to reduce the oxidative stress of diabetes by flavonoides treatment.

关键词： Tested Plants: Cleome Droserfolia (Sommo) Jumiperus Phoenicia (Araar) Anostatica Hierochuntica (Kafta) And Hyphened Thebaica (Doum) Alloxan Pregnant Females Albino Rats Diabetes Mellitus

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