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Endophytes and associated marine derived fungi—ecological and chemical perspectives

Fungal Diversity 2012年第6期57卷 45-83页

作者： abdessamad debbab Amal H.Aly Peter Proksch Heinrich-Heine-Universität Düsseldorf Institut für Pharmazeutische Biologie und BiotechnologieUniversitätsstr.1Geb.26.2340225 DüsseldorfGermany

The potential of endophytes and algal or invertebrate associated marine derived fungi as promising sources of structurally unprecedented bioactive natural products is undeniable and continues to attract broad *** review highlights new bioactive fungal metabolites reported in 2011 until April 2012,as well as known compounds for which novel biological activities have been *** compounds are grouped according to their reported biological activities which include cytotoxic,anti-infective,as well as radical scavenging,enzyme inhibition,anti-fouling and anti-parasitic ***,178 fungal metabolites,including 138 new natural products are ***,new insights into fungal-host interaction,chemical communication,and chemo-ecological roles of fungal metabolites,as well as new strategies for bioprospecting are presented.

关键词： Fungi Endophytes Associated marine fungi Bioactive metabolites Natural products Biosynthetic pathways

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Mangrove derived fungal endophytes–a chemical and biological perception

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Fungal Diversity 2013年第4期61卷 1-27页

The potential of mangrove-derived endophytic fungi as a promising source of diverse and structurally unprecedented bioactive natural products is unquestionable and continues to attract considerable *** review highlights new bioactive mangrove fungal metabolites and known compounds with hitherto unreported biological activities described during the last 10 *** compounds are categorized according to their reported biological activities,including cytotoxic,anti-infective,in addition to a wide range of miscellaneous activities such as protein kinase,αglucosidase,acetylcholinesterase and tyrosinase inhibitory activities,as well as antiangiogenic and neovascularisation effects,radical scavenging,DNA-binding affinity,and calcium and potassium channel blocking activity.

关键词： Fungi Endophytes Mangroves Bioactive natural products

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