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International Journal of Nursing Sciences 2024年第2期11卷 187-196,I0002页

作者： Nadia Al Wachami Mohamed Chahboune Ibtissam Youlyouz-marfak Mohamed Reda Mesradi Hajar Lemriss abderraouf hilali Hassan First University of Settat Higher Institute of Health SciencesLaboratory of Sciences and Health TechnologiesSettatMorocco

目的模拟训练(simulation-based training,SBT)是一种有效的教育方法,广泛应用于包括肿瘤学在内的多种临床环境中。该文对肿瘤学中与SBT相关的研究进行了范围综述,全面了解SBT在提高医护人员技能方面的作用,从而提高护理质量和患者安全... 详细信息

目的模拟训练(simulation-based training,SBT)是一种有效的教育方法,广泛应用于包括肿瘤学在内的多种临床环境中。该文对肿瘤学中与SBT相关的研究进行了范围综述,全面了解SBT在提高医护人员技能方面的作用,从而提高护理质量和患者安全。方法根据Arksey和O’Malley提出的范围综述方法框架,在Medline、Scopus和Web of Science数据库中检索于2012年至2022年发表的,与SBT在提高肿瘤科医护人员技能方面的相关研究文献,仅纳入经过同行评审的英文或法语文献。由2名研究员独立进行文献的筛选、提取和分析。结果检索出1013篇文章,共纳入29篇文献。其中25篇文献侧重于非技术技能,如决策技能、沟通和团队合作技能以及认知能力;13篇文献侧重于技术技能。纳入文献研究结果表明,通过SBT项目,肿瘤科医护人员的技能得到了显著提高。其中14篇文献对SBT的应用进行了主观评估,9篇文献对其进行了客观评估,6篇文献采用了主观和客观相结合的评估方法。结论SBT是提高肿瘤科医护人员技能的有效方法,支持和推广SBT对提供高质量的医疗服务和确保患者安全至关重要。

关键词：护士肿瘤科患者安全卫生保健质量模拟训练

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Incidence of Extended-Spectrum Be-ta-Lactamase-Producing Klebsiella pneumoniae among Patients and in the Environment of Hassan II Hospital, Settat, Morocco

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Advances in Microbiology 2016年第3期6卷 152-161页

作者： Samira Natoubi Abouddihaj Barguigua Sanaa Bouhali Zriouil Nezha Baghdad Mohammed Timinouni abderraouf hilali Souad Amghar Khalid Zerouali Microbiology Laboratory Hassan II Hospital Settat Morocco Agrofood and Health Laboratory Faculty of Science and Technology University Hassan I Settat Morocco Molecular Bacteriology Laboratory Pasteur Institute of Morocco 1 Place Louis Pasteur Casablanca Morocco Microbiology Laboratory University Hospital Center Ibn Rochd 1 Street Hospital Casablanca Morocco Laboratory of Improved Soil Productivity and Environment University Mohammed V Higher Normal School Rabat Morocco Faculty of Medicine and Pharmacy University Hassan II Casablanca Morocco

Aim: The aim of the current study is to determine: (1) the prevalence of extended-spectrum β-lactamase-producing K. pneumoniae (ESBL-Kp) isolated from clinical samples and a hospital environment in Hassan II Hospital (Settat, Morocco);(2) the associated risk factors of ESBL-Kp infections;(3) the link between clinical and environmental isolates. Methods: During the study period (April 2010 to March 2011), all patients infected and hospital environment sites contaminated by K. pneumoniae were considered as the potential study population and environmental site. The clinical data were collected to identify risk factors for ESBL carriage of K. pneumoniae infection. Screening of ESBL-and carbapenemase-producing isolates was performed by using a double-disk synergy test and the modified Hodge test, respectively. ESBL-Kp isolates were tested for the presence of genes encoding β-lactamases and were investigated by PCR. The clonal relationship between ESBL-producing isolates was analysed by ERIC- and REP-PCR method. Results: The overall prevalence of ESBL-Kp among clinical and environmental K. pneumoniae isolates was 35.13% (13/37) and 4.04% (4/99), respectively. The main risk factors for carrying ESBL-Kp were renal disease (46.15%), recent surgery (53.84%), previous hospitalisation (76.92%), and the presence of many invasive devices (53.84%). All ESBL isolates were multidrug resistant. The blaCTX-M group1and blaSHV (70.58% for each) were the most prevalent followed by blaTEM (52.94%). Thirteen strains expressed at least two bla genes. One isolate was positive in the modified Hodge test and was a blaOXA-48 producer. ERIC and Rep-PCR methods revealed an epidemic clonal dissemination of these isolates. Conclusion: The emergence of OXA-48 carbapenemase, endemic clonal dissemination and multi-drug resistance of ESBL-Kp isolates in our institution is highly alarming.

关键词： ESBL-Producing K. pneumoniae Infections Hospital Environment Risk Factors

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Chromosomal Abnormalities in 238 Couples with Recurrent Miscarriages in Morocco

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Open Journal of Genetics 2018年第2期8卷 15-22页

作者： Hanane Houmaid Chadli El Bekkay Sanaa Nassereddine Hayat Talbi Loubna Amehdare abderraouf hilali Department of Gyneacology and Obstetrics Mohammed VI Hospital Chichaoua Morocco Department of Cytogenetics Institut Pasteur Casablanca Morocco Health and Food-Processing Industry Laboratory Faculty of Sciences and Technics Hassan 1st University Settat Morocco High Institut of Health Sciences Hassan 1st University Settat Morocco

Purpose: A proportion of cases with repeated abortion are caused by chromosomal abnormality in one of the parents. The purpose of this study was to assess the frequency and nature of chromosomal aberrations that contribute to the occurrence of recurrent miscarriages. Several studies have been done to determine the role of chromosomal abnormalities in couples with recurrent spontaneous abortion in various countries. None of these studies was done in Morocco. Material and Methods: Cytogenetic study was done for 238 Moroccan couples who presented with repeated abortion at the Institut Pasteur, Casablanca, Morocco. Results: We found that the frequency of chromosomal abnormalities was not significantly different from that reported worldwide. Chromosomal abnormalities were detected in 13 (6.1%) of 238 couples. twelve of chromosomal abnormalities were structural and one of them were numerical. Conclusion: This study highlights the importance of constitutional cytogenetic exploration of couples with a history of repeated spontaneous abortion. Cytogenetic findings could provide valuable information for genetic counseling and allow monitoring of future pregnancies by prenatal diagnosis in couples with a history of recurrent miscarriage.

关键词： Cytogenetics Recurrent Abortions Chromosomal Aberrations

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