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The Histological Variants of Urothelial Carcinoma of the Bladder: It Is Affecting the Prognosis?

Open Journal of Pathology 2020年第1期10卷 24-34页

作者： Souhail Regragui Mohammed Alae Touzani Amine Slaoui Anas Mehedra Hafsa Elouazzani Tariq Karmouni Khalid El Khader abdellatif koutani Najat Mahassini Ahmed Ibn Attya Andaloussi Faculty of Medicine and Pharmacy Mohammed 5 University Rabat Morocco “B” Urology Department Ibn Sina Hospital Rabat Morocco Pathology Department Ibn Sina Hospital Rabat Morocco

Urothelial carcinomas (UC) are likely to have particular morphological features that distinguish them from the typical form. These original aspects are called “histological variants of urothelial carcinoma”. They can constitute all or part of the tumor and concern mainly muscle invasive UC and high grade. Their frequency varies according to the type, but the knowledge of these variants is essential because of the diagnostic difficulties, and the implication of their presence on the prognosis.

关键词： Urothelial Carcinoma Variants Prognosis

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Post-Obstructive Diuresis: Physiopathology, Diagnosis and Management after Urological Treatment of Obstructive Renal Failure

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Open Journal of Urology 2018年第9期8卷 267-274页

作者： Sumba Harrison Abdelouahed Lasri Youness Jabbour Amine Slaoui Jacquet Djamal Tariq Karmouni Kadir El Khader Abdelatif koutani Ahmed Ibn Attiya Andaloussi Department of Urology “B” Ibn Sina University Hospital Rabat Morocco Faculty of Medicine and Pharmacy Mohamed V University Rabat Morocco Department of Uro-Andrology Faculty of Health Sciences Cotonou Benin

Obstructive acute renal failure is both a medical and a surgical emergency. The first treatment modality is urological by relief of obstruction. Post-obstructive diuresis is an abnormal condition of prolonged polyuria, involving both excessive solute and water loss, after acute drainage of obstructed urinary tract system. Physiopathology mechanisms are multiples. In most patients, diuresis will resolve once the kidneys normalize the volume and solute status and homeostasis is achieved. Post-obstructive diuresis can occur in up to 50% of patients with substantial urinary tract obstruction and can be life-threatening if it becomes pathologic. It can be detected by hourly monitoring of diuresis. Medical treatment of post-obstructive diuresis consists of oral or intravenous fluids adjusted to the findings of clinical examination, diuresis (volume and electrolytes) and close monitoring of patient. Fluid compensation should be tapered off over several days. Patients at high risk of post-obstructive diuresis should be identified and appropriately monitored.

关键词： Post-Obstructive Diuresis Acute Renal Failure Water and Electrolyte Compensation

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Cystitis Glandularis: A Rare Benign Condition Presenting as Bladder Tumor

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Open Journal of Urology 2018年第12期8卷 336-343页

作者： Sumba Harrison Hamza Lamchahab Jacquet Djamal Youness Jabbour Touzani Alae Tariq Karmouni Kadir El Khader Abdelatif koutani Ahmed Ibn Attiya Andaloussi Department of Urology “B” Ibn Sina University Hospital Rabat Morocco Faculty of Medicine and Pharmacy Mohamed V University Rabat Morocco Department of Uro-Andrology Faculty of Health Sciences Cotonou Benin

Cystitis glandularis or glandular metaplasia of the urinary bladder, is a benignreactive metaplasia of the urothelium, which occurs in the context of chronic irritation, in less than 2% of the general population. It is a condition in most casesasymptomatic, but also characterized by nonspecific symptoms and paraclinical findings, which is why this condition is underdiagnosed. Its evolution is mainly focused on the risk of malignant degeneration. This condition affects men much more commonly than women. Two forms of cystitis glandularis are recognized: typical and intestinal form. They differ in their histology, incidence, difficulty of diagnosis, and possible association with adenocarcinoma of the bladder. Diagnosis of certainty is histological by careful analysis of chips from bladder endoscopic resection. This rare pathology is managed by endoscopic bladder resection, with repeated cystoscopy as a monitoring tool. Extensive surgical is needed in severe or recurrent cases. We present here-in a case of a female patient having cystitis glandularis presenting with lower urinary tract symptoms. We review equally data reported in literature. To the best of our knowledge our case represents the fourth case of cystitis glandularis affecting a female patient reported in the English literature so far.

关键词： Cystitis Glandularis Cystoscopy Bladder Resection

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