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Colonic schistosomiasis:A case report

World Journal of Gastrointestinal Endoscopy 2022年第12期14卷 789-794页

作者： Hajar Koulali abdelkrim zazour Wafaa Khannoussi Ghizlane Kharrasse Zahi Ismaili Department of Gastro-enterology Mohammed VI University HospitalOujda 60050Morocco

BACKGROUND Schistosomiasis is a chronic parasitic infection endemic in many *** schistosomiasis is a rare entity with no specific clinical manifestations or endoscopic aspects,which delays the *** is primarily dependent on histopathological analysis,and treatment with antihelminthics typically resolves the *** SUMMARY We present the case of a 21-year-old male who suffered from chronic diarrhea and abdominal *** examination found no abnormalities,blood tests were normal,and stool examination was negative.A colonoscopy revealed a nodular terminal ileal mucosa,two cecal polypoid lesions with no particular surface pattern,and millimetric erosions in the *** presence of Schistosoma eggs with thick peripheral capsules and viable embryos inside and numerous eosinophils surrounding the egg capsule were observed on histopathological *** patient received praziquantel,and his symptoms were *** Colonic schistosomiasis should be considered as a differential diagnosis,especially in endemic *** and histopathological examination can confirm the diagnosis,and antihelminthics are an effective treatment.

关键词： Schistosoma Colon Polyps Colonoscopy Histopathology Ova

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Compound Heterozygous C282Y/H63D Mutation in Hemochromatosis: A Case Report

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Open Journal of Clinical Diagnostics 2016年第3期6卷 30-35页

作者： zazour abdelkrim Wafaa Khannoussi Amine El Mekkaoui Ghizlane Kharrasse Zahi Ismaili Hepato-Gastro-Enterology Unit Mohammed VI University Hospital Oujda Oujda Morocco

Hereditary hemochromatosis is a condition characterized by iron overload, which is both treatable and preventable. It’s mainly related to hepcidin deficiency related to mutations in genes involved in hepcidin regulation. Iron overload increases the risk of disease such as liver cirrhosis, heart disease and diabetes. Two HFE genotypes have been commonly described in cases of iron overload, C282Y homozygosity and C282Y/H63D compound heterozygoty. The diagnosis of this rare disease now can be explored by biological and imaging tools. We report a case of compound heterozygous C282Y/H63D discovered by family screening for elevated serum ferritin.

关键词： Iron Overload Compound Heterozygoty Phlebotomy

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Solitary pancreatic metastasis from squamous cell lung carcinoma: A case report and review of literature

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World Journal of Gastrointestinal Endoscopy 2022年第7期14卷 455-466页

作者： Kaouthar Rais Oumayma El Eulj Najoua El Moutaoukil Imane Kamaoui Amal Bennani Ghizlane Kharrasse abdelkrim zazour Wafaa Khannoussi Zahi Ismaili Department of Hepatogastroenterology Mohammed Ⅵ University Hospital CenterDigestive Disease Research LaboratoryMedical SchoolMohammed Ⅰ UniversityOujda 60000Morocco Department of Radiology Mohammed Ⅵ University Hospital CenterDigestive Disease Research LaboratoryMedical SchoolMohammed Ⅰ UniversityOujda 60000Morocco Department of Anatomo-Pathology Mohammed Ⅵ University Hospital CenterDigestive Disease Research LaboratoryMedical SchoolMohammed Ⅰ UniversityOujda 60000Morocco

BACKGROUND Pancreatic metastases from squamous cell lung carcinoma(SCLC)are *** lesions are often asymptomatic and detected incidentally or during followup investigations,occasionally several years after removal of the primary *** SUMMARY A 56-year-old male with SCLC developed jaundice 1 mo after the cancer *** abdominal computed tomography(CT)scan showed a mass in the pancreatic head with distention of both intra-and extrahepatic biliary *** retrograde cholangiopancreatography and sphincterotomy were performed first,culminating with plastic biliary stent *** examination of the pancreatic mass sample collected by fine-needle aspiration(FNA)under endoscopic ultrasound(EUS)guidance revealed the presence of malignant cells compatible with well-differentiated squamous cell *** liver function normalized,chemotherapy was initiated with carboplatin and paclitaxel;however,4 d later,the patient presented ***-thoracoabdominal CT showed tracheoesophageal fistula and stent *** replacement with a 10 cm/10 mm uncovered metallic biliary stent and treatment of the tracheoesophageal fistula with a fully covered esophageal stent,the patient was able to start oral feeding *** died 9 mo after the initial *** The diagnosis of pancreatic metastasis from SCLC is challenging for ***-FNA is the primary exam for confirmatory diagnosis.

关键词： Squamous cell lung carcinoma Pancreatic metastasis Jaundice Esotracheal fistula Ultrasound endoscopy Case report

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