检索结果-南通市图书馆

Genetic Analysis of Familial Mediterranean Fever among Egyptian Patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Immunology 2022年第4期12卷 137-147页

作者： Marwa A. Besar Adel Abd el Salam Asmaa F. Enein Samar Tharwat Radwan Fatma Hamdy Fouad Abeer saad Ali el Zekred Nehed Abdallah Hassan Internal Medicine (Rheumatology & Immunology) Mansoura School of Medicine Mansoura University Al Mansoura Egypt Department of Biochemistry Specialized Medical Hospital Specialised Medical Hospital Mansoura Egypt Specialised Medical Hospital Mansoura Egypt

Background: Familial Mediterranean fever (FMF) is an autoinflammatory genetic disorder that associated with different genetic mutations. Frequency of clinical manifestation differs according to age group, geographic region and ethnic population. Objectives: To study the clinical manifestation of FMF in relation to genotype (M680I, M694V, M694I and V726A). Result: The main presentation of studied group was abdominal pain 65.9% (203), followed by fever 60.4% (186) patients. (Mutation M694V) was the commonest 47.6% (297), followed by (Mutation V726A) in 32.8% (169%), then (Mutation M6802) in 23.4% (121) lastly (Mutation M6941) was in 22.1% (114) patients. Fever was highly associated with mutation (V729A) and it was statistically significant (*p value 0.047). Conclusion: Abdominal pain and fever were the most common manifestation of FMF patients. (Mutation M694V), (Mutation V726A) were the most detected mutation. Third age group;fever was associated with genetic mutation (V726A), abdominal pain with (M6941).

关键词： Familial Mediterranean Fever (FMF) MEFV Gene Mutation (M680I M694V M694I and V726A) Fever Abdominal Pain Autoinflammatory

Role of Ischemia Modified Albumin in Diagnosis of Pulmonary Embolism

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Respiratory Diseases 2014年第1期4卷 22-26页

作者： Ashraf Abd el Halim Adel Attia saad Samra Tayseer Zytoun Hosam eldeen Salah Manal Al-Anazi Chest Department Faculty of Medicine Zagazig University Zagazig Egypt Clinical Pathology Department Faculty of Medicine Zagazig University Zagazig Egypt Critical Care Department Faculty of Medicine Alexandria University Alexandria Egypt Resident Internal Medicine King Fahad Specialist Hospital Dammam KSA

Pulmonary embolism is a common and potentially lethal condition. Clinical signs and symptoms for pulmonary embolism are nonspecific. New and simple tests are therefore needed in order to help in early diagnosis of pulmonary embolism. The aim of this work is to elucidate the role of IMA in the diagnosis of pulmonary embolism. Subjects and Methods: 75 patients with suspected pulmonary embolism and 20 control healthy subjects were included in this study. Measurement of IMA was done in all subjects. Results: The mean values of IMA were statistically significantly higher among the PE patient group (0.43 ± 0.104 ABSU) in comparison with non PE patient group (0.27 ± 0.053 ABSU) and healthy control subjects (0.21 ± 0.080 ABSU). At cut-off value of 0.305 ABSU, IMA had 97.5% sensitivity and 71.42% specificity. The area under the curve was 0.952. The positive predictive value of this cut-off value was 79.59% while the negative predictive value was 96.15%. Conclusions: IMA is a good alternative to D-dimer in the diagnosis and exclusion of PE. Larger studies are needed to augment our results.

关键词： Ischemia Modified Albumin D-Dimer Pulmonary Embolism

Gene expression of 49 kDa apyrase,cytoskeletal proteins,ATPase,ADPase and amino acid contents of Pisum sativum(L.)cells germinated in Euryops arabicus(*** Jaub.&Spach)water extract

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

BIOCelL 2019年第2期43卷 81-87页

作者： MAHMOUD MOUSTAFA saad ALAMRI HOIDA ZAKI NAGLAA LOUTFY TAREK TAHA ALI SHATI MOHAMED ALKAHTANI SAJDA SIDDIQI Department of Biology College of ScienceKing Khalid University9004AbhaKingdom of Saudi Arabia(KSA) Department of Botany Faculty of ScienceSouth Valley UniversityQenaEgypt Environmental Biotechnology Department Genetic Engineering and Biotechnology Research Institute(GEBRI)City of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab City21934AlexandriaEgypt

The present research reports of quick and marked changes induced by plant extract of Euryops arabicus in the gene expression of 49-kDa apyrases,cytoskeletal proteins,ATPases,ADPase and amount of amino acid of pea(Pisum sativum ***).Pellets of cytoskeletals proteins(27000 xg)were probed with anti-apyrase antibody,biotinylated anti-rat,actin and alpha and beta-tubulin for Western *** and ADPase activities were determined based on the hydrolytic efficacy of adenine triphosphate and adenine *** 72 hours,the abundance of apyrases,cytoskeletal proteins and amount of amino acid in pellets of 27000 xg of germinated pea seeds in *** extracts were sharply increased than those sown in distilled *** the samples exhibited that the stems had more amount from apyrases,cytoskeletal proteins,amino acids and ATPase and ADPase activities than primary leaves and primary roots that were germinated either on *** water extract or in distilled *** on the enzyme’s capability to hydrolyse nucleotide triphosphate and nucleotide diphosphate as well as the direct association between expression of 49-kDa apyrase and cytoskeletal proteins,*** water extract had an important effect on plant germinations.

关键词： Cytoskeletal proteins ATPase ADPase Pisum sativum Euryops arabicus

Massive Rhinorrhea as a Complication of COVID-19 Nasopharyngeal Swab

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Modern Neurosurgery 2023年第3期13卷 145-148页

作者： Inas el Kacemi Yao Christian Hugues Dokponou Fresnel Lutèce Ontsi Obame Moussa elmi saad Napoleao Imbunhe Salami Mohcine Abad Cherif el Asri Miloud Gazzaz Department of Neurosurgery Military Teaching Hospital Mohammed V University Rabat Morocco

The nasopharyngeal swab for COVID-19 testing is generally considered safe;however, it is primarily performed by staff that may not completely understand the anatomy of the nasal cavity and nasopharynx. We report the treatment of a 48-year-old man who developed unilateral left rhinorrhea after a nasopharyngeal swab sample. It is aimed to draw attention to this complication that can be prevented with the appropriate technique during nasopharyngeal swab sampling.

关键词： COVID-19 Testing Nasopharyngeal Swab Rhinorrhea

Gamma induced changes in Makrofol/CdSe nanocomposite films

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2022年第9期31卷 547-553页

作者： Ali A.Alhazime M.ME.Barakat Radiyah A.Bahareth E.M.Mahrous saad Aldawood S.Abd el Aal S.A.Nouh Physics Department Faculty of ScienceTaibah UniversityMedinaSaudi Arabia Department of Physics Faculty of ScienceTaibah UniversityYanbuSaudi Arabia Department of Physics Faculty of ScienceAlexandria UniversityAlexandriaEgypt Physics Department College of ScienceJeddah UniversityJeddahSaudi Arabia Department of Physics and Astronomy College of ScienceP.O.BOX 2455King Saud UniversitySaudi Arabia Center of Radiation Research and Technology Egyptian Atomic AuthorityNasr CityCairoEgypt Qassim University P.B.6644Buraidah 51452QassimSaudi Arabia Physics Department Faculty of ScienceAin Shams UniversityCairoEgypt

We applied an ex-situ casting procedure to prepare a nanocomposite(NCP)from Makrofol polycarbonate(PC)and CdSe *** CdSe nanoparticles were prepared by a thermolysis procedure in the presence of N_(2) gas *** refinement of x-ray data illustrated that the CdSe adopts a cubic zinc blend structure of 6.057 A lattice parameter and 2 nm typical grain *** from the prepared NCP were exposed to γ dosages(20 kGy-250 kGy).The modifications induced in the NCP films owing to γ dosages have been ***γirradiation(50 kGy-250 kGy)causes crosslinks that reduce the optical bandgap from 4.15 eV to 3.81 eV,associated with an increase in dielectric parameters and refractive *** is attributed to an increase in the mass fraction of the disordered regions as specified by x-ray *** PC-CdSe NCP was found to have a reaction to color modification which makes it suitable for saleable reproduction on a printing press.

关键词： gamma nanocomposite x-ray dfraction UV spectra color changes

Nature-Inspired Level Set Segmentation Model for 3D-MRI Brain Tumor Detection

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2021年第7期68卷 961-981页

作者： Oday Ali Hassen Sarmad Omar Abter Ansam A.Abdulhussein saad M.Darwish Yasmine M.Ibrahim Walaa Sheta Department of Computer Techniques Engineering Imam Al-Kadhum College(IKC)WasitIraq University of Information Technology and Communications Media Technology Engineering DepartmentIraq University of Information Technology and Communications Baghdad10081Iraq Department of Information Technology Institute of Graduate Studies and ResearchAlexandria University63 Horreya AvenueEl–ShatbyAlexandria21526Egypt Informatics Research Institute City of Scientific Research and Technology ApplicationsBorg EL Arab21934Egypt

Medical image segmentation has consistently been a significant topic of research and a prominent goal,particularly in computer *** tumor research plays a major role in medical imaging applications by providing a tremendous amount of anatomical and functional knowledge that enhances and allows easy diagnosis and disease therapy *** prevent or minimize manual segmentation error,automated tumor segmentation,and detection became the most demanding process for radiologists and physicians as the tumor often has complex *** methods for detection and segmentation presently exist,but all lack high *** paper’s key contribution focuses on evaluating machine learning techniques that are supposed to reduce the effect of frequently found issues in brain tumor ***,attention concentrated on the challenges related to level set *** study proposed in this paper uses the Population-based Artificial Bee Colony Clustering(P-ABCC)methodology to reliably collect initial contour points,which helps minimize the number of iterations and segmentation errors of the level-set *** proposed model measures cluster centroids(ABC populations)and uses a level-set approach to resolve contour differences as brain tumors vary as they have irregular form,structure,and *** suggested model comprises of three major steps:first,pre-processing to separate the brain from the head and improves contrast ***,P-ABCC is used to obtain tumor edges that are utilized as an initial MRI sequence *** level-set segmentation is then used to detect tumor regions from all volume slices with fewer *** suggest improved model efficiency compared to state-of-the-art methods for both datasets BRATS 2019 and BRATS *** BRATS 2019,dice progress was achieved for Entire Tumor(WT),Tumor Center(TC),and Improved Tumor(ET)by 0.03%,0.03%,and 0.01%*** BRATS 2017,an increase in precision for WT was reac

关键词： 3D-MRI tumor diagnosis bio-inspired clustering ABC optimization multimodal detection

Component Analysis and Antifungal Activity of the Compounds Extracted from Four Brown Seaweeds with Different Solvents at Different Seasons

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Ocean University of China 2018年第5期17卷 1178-1188页

作者： MOHY el-DIN Soad M. MOHYelDIN Mohamed M. Botany and Microbiology Department Faculty of ScienceAlexandria UniversityAlexandria 21511Egypt Pharmacognosy Department Faculty of PharmacyAlexandria UniversityAlexandria 21521Egypt

The polar and nonpolar extracts of Colpomenia sinuosa, Padina pavonia, Cystoseira barbata and Sargassum vulgare collected during spring, summer and autumn were evaluated for their antifungal activities. The phytochemicals of unexplored seaweeds were analyzed by gas chromatography and mass spectrometric （GC/MS）. The algal extracts were tested for their antifungal activities against Aspergillus niger, A. flavus, Penicillium parasiticus, Candida utilis and Fusarium solani. Phytochemicals were extracted from the four seaweeds with various solvents including methanol, ethanol, acetone, chloroform and dimethyl ether. Among the various extracts, methanolic extract showed the highest inhibition activity on all fungal species. Seasonal variation in antifungal activity was studied, while methanol extracts showed the best antifungal activity in spring. Cystoseira barbata was the most effective seaweed, having anatifungal activity throughout the whole year. The UV-Vis phytochemical procedure and GC-MS analysis of the methanol extracts from tested species indicated the existence of different constituents. In conclusions, the compounds with antifungal activity were identified as indoles, terpenes, acetogenins, phenols, and volatile halogenated hydrocarbons.

关键词： antifungal activity GC/MS UV-Vis macroalgae seasonal variation

The Need to Autonomous Radiosounding System

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Geodesy and Geomatics Engineering 2015年第1期2卷 53-58页

作者： Ahmed saad Abd-elnaby The Egyptian Meteorological Authority Koubry El-Quobba Cairo 11784 Egypt

In recent years, the upper air radiosounding system based on GPS （global positioning system） is used as an effective method resulting to improving observation accuracy and helping in simplification of the ground equipment. GPS is used to calculate the pressure and wind speed and direction. The NAVSTAR GPS has been developed by the Department of Defense of the United States, and the main purpose is to provide the military forces of the USA and its allies with a means to accurately determine their position, velocity and time, anywhere on the earth, at any time. Europe is now developing its own GPS, known as Galileo, which is independent of the USA GPS. As a result, many countries now are developing their own GPS system like Russia （GLONASS）, China （Compass）, India, and Japan. As a direct result, we can face the fact that each and every country will have its own GPS system and finally we come up with a crowded space. The INS （inertial navigation system） is a system that, once initialized （by acquiring the initial position, velocity, and orientation information）, becomes an autonomous navigation system providing 3-D position, velocity, and attitude information. So upper air observation can take advantage of this emerging technology by using this stand alone system （INS） in measuring wind speed and direction as well as measuring the altitude we can calculate the pressure.

关键词： Global positioning system inertial navigation system upper air observation.

How to Return the Death Programs of Cancer Cells to Work again and Cure Cancer within a Short Time?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CellBio 2019年第2期8卷 17-39页

作者： Mahmoud saad Mohamed el-Khodary Sahar Ezeldien Hasan Wael A. Hassan Maather M. el-Lamie Ismail A. M. Eissa Waleed F. Khalil Salah M. Aly Suez Canal University Ismailia Egypt General Organization for Export and Import Control Suez Egypt Pharmacology Department Faculty of Vet. Medicine Suez Canal University Ismailia Egypt Pathology Department Faculty of Medicine Suez Canal University Ismailia Egypt Department of Basic Sciences Suliman Al-Rajhi Collage of Medicine Al Bukayriyah KSA Department of Fish Diseases & Management Faculty of Vet. Medicine Suez Canal Univ. Ismailia Egypt Pathology Department Faculty of Vet. Medicine Suez Canal University Ismailia Egypt

Cancer is cell fleeing from death by blocking the intrinsic and extrinsic pathways of cell death programs. In the present work, the experimental formula was designed to remove these blockers. It was applied on 120 Swiss albino mice which were inoculated intraperitoneally and subcutaneously with Ehrlich Ascites Carcinoma cells;1 × (106) cell/mouse. The activity of the cell death programs of the tumor was detected by measuring the volume of Ascites fluid, counting the number of dead cancer cells, measuring the size of the tumor, detecting the positive reaction of caspase enzyme in cancer cells and presence of macrophages and apoptotic bodies in tumor tissue. The experimental formula succeeded in removing the blockers of the cell death program in cancer cells returning the cell death program to work again.

关键词： Cancer Therapeutic Strategy Accumulation Detoxification Enzymes Free Radicals Antioxidants H2O2 Glutathione NF-kB Sulforaphane Flavonoid Cur Cumin