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Prevalence and risk factors associated with metabolic dysfunctionassociated steatohepatitis in patients with Helicobacter pylori infection: A population-based study

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World Journal of Hepatology 2024年第10期16卷 1169-1176页

作者： Rashid abdel-Razeq Lynn Bitar Elio R Bitar Chidera Onwuzo Mohamad-Noor abu-Hammour Barish Eren Islam Mohamed Adejoke Johnson Antoine Boustany Somtochukwu Onwuzo Imad Asaad Department of Internal Medicine Cleveland Clinic FoundationClevelandOH 44111United States Faculty of Medicine Saint Joseph University of BeirutBeirut 11042020Lebanon Faculty of Medicine American University of BeirutBeirut 11072020Lebanon Department of Medicine&Surgery General Hospital Lagos IslandLagos Island 101223LagosNigeria Department of Internal Medicine Jacobi Medical Center/North Central Bronx HospitalBronxNY 10461United States Division of Gastroenterology Department of Internal MedicineUniversity of Florida College of MedicineJacksonvilleFL 32209United States Department of Gastroenterology Allegheny General HospitalPittsburghPA 15212United States Department of Gastroenterology Firelands HealthSanduskyOH 44870United States

BACKGROUND Helicobacter pylori(***)is associated with the development of gastrointestinal disorders ranging from gastritis to gastric *** evidence of the association between metabolic dysfunction-associated steatohepatitis(MASH)and *** infection in the literature is ***,we aim to evaluate the risk of developing MASH in patients who have had a diagnosis of *** infection independently of any confounding *** To evaluate the risk of developing MASH in patients who have had a diagnosis of *** *** This study used a validated multicenter research database of over 360 hospitals across 26 healthcare systems across the United States from 1999 to *** regression analysis assessed the risk of developing MASH,adjusting for confounders including *** infection,obesity,type 2 diabetes,hypertension,dyslipidemia,and male gender.A two-sided P value<0.05 was considered as statistically significant,and all statistical analyses were performed using R version 4.0.2(R Foundation for Statistical Computing,Vienna,Austria,2008).RESULTS A total of 79476132 individuals were screened in the database and 69232620 were selected in the final analysis after accounting for inclusion and exclusion ***(14.30%),patients with hyperlipidemia(70.35%),hypertension(73.86%),diabetes mellitus type 2(56.46%),and obese patients(58.15%)were more common in patients with MASH compared to *** a multivariate regression analysis,the risk of MASH was increased in diabetics[odds ratio(OR):3.55;95%CI:3.48-3.62],obese(OR:5.93;95%CI:5.81-6.04),males(OR:1.49;95%CI:1.46-1.52),individuals with hyperlipidemia(OR:2.43;95%CI:2.38-2.49)and *** infection(OR:2.51;95%CI:2.31-2.73).CONCLUSION This is the largest population-based study in the United States illustrating an increased prevalence and odds of developing MASH in patients with *** infection after adjusting for risk factors.

关键词： Metabolic dysfunction-associated steatohepatitis Metabolic dysfunction-associated steatotic liver disease Helicobacter Pylori Cirrhosis Liver

Performance Comparison of Hyper-V and KVM for Cryptographic Tasks in Cloud Computing

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Computers, Materials & Continua 2024年第2期78卷 2023-2045页

作者： Nader abdel Karim Osama A.Khashan Waleed K.Abdulraheem Moutaz Alazab Hasan Kanaker Mahmoud E.Farfoura Mohammad Alshinwan Department of Intelligent Systems Faculty of Artificial IntelligenceAl-Balqa Applied UniversityAl-Salt1705Jordan Research and Innovation Centers Rabdan AcademyP.O.Box 114646Abu DhabiUnited Arab Emirates Department of Information Systems and Networks TheWorld Islamic Sciences and Education UniversityAmman11947Jordan Department of Cyber Security Isra UniversityAmman1162Jordan Faculty of Science and Information Technology Al-Zaytoonah University of JordanAmman11733Jordan Middle East University Research Unit Middle East UniversityAmman11831Jordan

As the extensive use of cloud computing raises questions about the security of any personal data stored there,cryptography is being used more frequently as a security tool to protect data confidentiality and privacy in the cloud environment.A hypervisor is a virtualization software used in cloud hosting to divide and allocate resources on various pieces of *** choice of hypervisor can significantly impact the performance of cryptographic operations in the cloud *** important issue that must be carefully examined is that no hypervisor is completely superior in terms of performance;Each hypervisor should be examined to meet specific *** main objective of this study is to provide accurate results to compare the performance of Hyper-V and Kernel-based Virtual Machine(KVM)while implementing different cryptographic algorithms to guide cloud service providers and end users in choosing the most suitable hypervisor for their cryptographic *** study evaluated the efficiency of two hypervisors,Hyper-V and KVM,in implementing six cryptographic algorithms:Rivest,Shamir,Adleman(RSA),Advanced Encryption Standard(AES),Triple Data Encryption Standard(TripleDES),Carlisle Adams and Stafford Tavares(CAST-128),BLOWFISH,and *** study’s findings show that KVM outperforms Hyper-V,with 12.2%less Central Processing Unit(CPU)use and 12.95%less time overall for encryption and decryption operations with various file *** study’s findings emphasize how crucial it is to pick a hypervisor that is appropriate for cryptographic needs in a cloud environment,which could assist both cloud service providers and end *** research may focus more on how various hypervisors perform while handling cryptographic workloads.

关键词： Cloud computing performance virtualization hypervisors Hyper-V KVM cryptographic algorithm

Evaluation of the Integrated Management Program for Acute Malnutrition in the Douentza Health District, Mopti Region, Mali

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Food and Nutrition Sciences 2024年第8期15卷 790-806页

作者： Abdoul salam Diarra Lamine Traore Mohamed Diarra Tawfiq abu Mamadou Traore Yacouba Guindo Sidi Sangare Seydou Kante Intimbeye Tembine Dramane Coulibaly Mamadou Fodé Diarra Salia Keita Sadio Sambala Diallo Mamadou Samake Hamadoun Sangho National Center for Scientific and Technological Research Bamako Mali Division of Nutrition Regional Directorate of Health and Public Hygiene Mopti Mali Department of Pediatric Health Referral Center of Kalaban Coro Koulikoro Mali Private Practice for Family and Emergency Medicine Casablanca Morocco Division of Nutrition General Directorate of Health and Public Hygiene Bamako Mali Administration Department Health Referral Center of Djenne Mopti Mali Administration Department Health Referral Center of Douentza Mopti Mali Administration and Planning Department Regional Health Directorate Mopti Mali Division of Health Department Regional Health Directorate of Mopti Mopti Mali Golden Life American Hospital Bamako Mali Department of Public Health Faculty of Medicine and Odontostomatology University of Sciences Techniques and Technologies of Bamako Bamako Mali

Introduction: Malnutrition is a major public health problem in Mali, despite the efforts of the government, its technical and financial partners. The aim of this study was to evaluate the integrated management program for acute malnutrition (IMPAM). Methodology: This was a descriptive cross-sectional study that took place from January to December 2020 in the Douentza health district. The study included anyone with at least one malnourished child aged 6 to 59 months in their care who agreed to take part in the study, community health center staff who had given their consent, and the URENI manager at the Douentza reference health center. Data collected via questionnaires were entered into Excel and then analyzed using Epi-Info version 7 software. Results: A total of 138 acutely malnourished children aged 6 - 59 months, including 71 girls (51.45%), 138 accompanying mothers and 11 health workers, were included in our case study. Among the malnourished, 54.34% were in the 12 - 23 months age group and 69.57% had the severe form. 93% of the mothers interviewed were satisfied with the care provided, and all the health staff interviewed stated that community conflicts had an impact on IMPAM’s activities. Cure rates were 81% in Moderate Outpatient Nutritional Recovery and Education Unit (URENAM), 84% in Severe Ambulatory Nutritional Recovery and Education Unit (URENAS) and 92% in Recovery and Intensive Nutritional Education Unit (URENI). Drop-out rates were 19% in URENAM, 16% in URENAS and 0% in URENI. The death rate was 8% in URENI and 0% in URENAM and URENAS. Conclusion: This study confirms the high prevalence of malnutrition in the district (10.54%). It also reveals that factors such as inter-community conflict and insecurity have seriously affected the IMPAM program.

关键词： Care Acute Malnutrition Children Aged 6 - 59 Months IMPAM Douentza

Gastric acid inhibitory and gastric protective effects of cannabis and cannabinoids

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Asian Pacific Journal of Tropical Medicine 2016年第5期9卷 401-408页

作者： Omar abdel-salam Department of Toxicology and Narcotics Medical Division National Research Centre

Cannabis sativa has long been known for its psychotropic effect. Only recently with the discovery of the cannabinoid receptors, their endogenous legends and the enzymes responsible for their synthesis and degradation, the role of this ‘endocannabinoid system’ in different pathophysiologic processes is beginning to be delineated. There is evidence that CB1 receptor stimulation with synthetic cannabinoids or Cannabis sativa extracts rich in ?9-tetrahydrocannabinol inhibit gastric acid secretion in humans and in experimental animals. This is specially seen when gastric acid secretion is stimulated by pentagastrin, carbachol or 2 deoxy-D-glucose. Cannabis and/or cannabinoids protect the gastric mucosa against noxious challenge with non-steroidal anti-inflammatory drugs, ethanol as well as against stress induced mucosal damage. Cannabis/cannabinoids might protect the gastric mucosa by virtue of its antisecretory, antioxidant, anti-inflammatory, and vasodilator properties.

关键词： Cannabis sativa Gastric mucosa Gastric acid

Therapeutic Profile and Prognostic Factors of Patients Suffering from Upper Digestive Bleeding at Sikasso Regional Hospital

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Open Journal of Gastroenterology 2024年第9期14卷 300-312页

作者： Oumar Traoré Abdoul salam Diarra Dramane Touré Tawfiq abu Amadou Boubeye Maïga Kadiatou Cissé Saïdon Touré Mohomedine Touré Aboudou Dolo Youana Koné Madou Traoré Mamadou Togo Kalba Péliaba Mamadou Samaké Hamadoun Sangho Service of Internal Medicine Regional Hospital Sikasso Mali National Center for Scientific and Technological Research Bamako Mali Department of Pediatric Health Referral Center of Kalaban Coro Koulikoro Mali Private Practice for Family and Emergency Medicine Casablanca Morocco Service of Nephrology Regional Hospital Sikasso Mali Department of Infectious Disease Regional Hospital Sikasso Mali Service de Mdecine Interne CHU Gabriel Tour Bamako Mali Service dHpato-Gastro-Entrologie CHU Gabriel Tour Bamako Mali Department of Public Health Faculty of Medicine and Odontostomatology University of Sciences Techniques and Technologies of Bamako Bamako Mali

Introduction: Upper digestive hemorrhage is one of the main digestive emergencies and remains a major cause of morbidity and mortality in Mali. The aim of this study was to describe the therapeutic profile and outcome of patients suffering from upper digestive haemorrhage. Methodology: This was a prospective study carried out in the internal medicine department of the Sikasso Regional Hospital from August 2022 to July 2023. All adult patients presenting with upper digestive haemorrhage and having given their consent, were included. Data were analyzed using SPSS version 21 software. Results: Sixty-three patients were enrolled. The mean age was 49.7 ± 18.99 years, with a male-female sex ratio of 2.2. Ruptured esophageal varices (37.5%) and peptic ulcer (25%) were the main etiologies. Pharmacological treatment was dominated by proton pump inhibitors (85.7%). Hemostasis endoscopy accounted for 3.17%. The evolution was marked by hemorrhagic arrest (69.84%), recurrence of hemorrhage (11.11%) and death (19.04%), the main cause of which was hemorrhagic shock (58.3%). We found no statistically significant relationship between prognosis and etiologies (P = 0.11), and length of hospital stay (P = 0.18). Conclusion: Hemostasis endoscopy remains a challenge for Sikasso Hospital. A holistic strategy of communication and community awareness-raising, combined with adequate technical facilities, will help to improve patient care and outcomes.

关键词： Digestive Hemorrhage Digestive Endoscopy Treatment Outcome

Factors Associated with Mortality in Children Aged 1 Month to 15 Years Hospitalized in the Pediatric Ward of the Kalaban-Coro Reference Health Center: Cross-Sectional Study

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Open Journal of Pediatrics 2024年第5期14卷 800-813页

作者： Abdoul salam Diarra Mohamed Diarra Dramane Touré Tawfiq abu Beyadari Balilé Harber Maimouna Kanté Issa Guindo Belco Maiga Karamoko Sacko Kalirou Traoré Fatoumata Dicko Mamadou Togo Kalba Pélieba Mariam Sylla Mamadou Samaké Hamadoun Sangho National Center for Scientific and Technological Research Bamako Mali Department of Pediatric Health Referral Center of Kalaban Coro Koulikoro Mali Pediatric Department of the Mopti Referral Health Center Mopti Mali Private Practice for Family and Emergency Medicine Casablanca Morocco Paediatric Ward of Nianankoro Fomba Hospital Segou Mali Paediatric Ward Referral Health Center of Common V Bamako Mali Administration Department Health Referral Center of Kalaban Coro Koulikoro Mali Department of Paediatrics Gabriel Toure University Hospital Bamako Mali Department of Internal Medicine CHU Gabriel Tour Bamako Mali Service dHpato-Gastro-Entrologie Gabriel Toure University Hospital Bamako Mali Department of Public Health Faculty of Medicine and Odontostomatology University of Sciences Techniques and Technologies of Bamako Bamako Mali

Introduction: Infant and child mortality is a worldwide concern, but developing countries such as Mali are more affected. The aim of this study was to investigate morbidity and factors associated with mortality in children aged 1 month to 15 years. Methodology: This was a cross-sectional study which took place from January 1 to December 31, 2020 covering children aged 1 month to 15 years hospitalized at the Kalaban-Coro CSRéf. Data were entered into Excel and analyzed using SPSS version 20 software. Results: Five hundred children aged 1 months to 15 years were included. The age range 1 to 5 years (53.6%) and male sex (58.2%) were the most represented. Malaria (72.2%), acute respiratory infections (6.2%) and diarrhea/dehydration (3%) were the main morbidities. Mortality was estimated at 10.6%, and the two main causes of death were malaria (56.6%) and acute respiratory infections (7.54%). Univariate analysis revealed a statistically significant association between the dependent variable (death) and age (p Conclusion: This study confirms the high rate of infant and child morbidity and mortality in our health facilities. Strengthening human resources and intensifying behavior-change communication can help reverse the trend.

关键词： Children Aged 1 Months to 15 Years Morbidity Factors Associated with Mortality Morbidity

Quasi-Periodic Structures Based on Symmetrical Lucas Function of (2+1)-Dimensional Modified Dispersive Water-Wave System

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Communications in Theoretical Physics 2009年第12期52卷 1004-1012页

作者： Emad A-B.abdel-salam Assiut University Department of MathematicsNew Valley Faculty of Education

By introducing the Lucas-Riccati method and a linear variable separation method, new variable separation solutions with arbitrary functions are derived for a （2＋1）-dimensional modified dispersive water-wave system. The main idea of this method is to express the solutions of this system as polynomials in the solution of the Riecati equation that the symmetrical Lucas functions satisfy. From the variable separation sohition and by selecting appropriate functions, some novel Jacobian elliptic wave structure with variable modulus and their interactions with dromions and peakons are investigated.

关键词： Lucas functions quasi-periodic structure variable separation excitations modified dispersive water-wave system

Factors Controlling Bioindicators For Industrial Pollution Detection

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Biomedical and Environmental Sciences 1999年第3期12卷 194-200页

作者： GAMILAH·ALI NAGLAAF·abdel－salam WaterPollutionResarchDepartment NationalResearchCenterDokkiCairoEgypt BotanyDepartment FacultyofGi

This study describes the use of algae as potential bioindicators of pollution containing industrial metals. Phytoplanktonic algae varied with waste type and with environmental and growth *** water samples containing cermic waste Euglenophyta species and Cyclotella sp. (Bacillariophyta) were determined as potential indicator species of pollution, while in sample containing metallic waste, Cyclolella sp. was most dominant. Under laboratory growth conditions, phytoplankton collected from a major stream of the Nile River were cultivated by using Algal Growth Bottle Test (EPA, 1972). This revealed that Scensdesmus sp., Actinastrum hantzschii (Chlorophyta), Oscillatoria limneica (Cyanophyta) and Nitzschia linearis (Bacilldriophyta) were also poential indicators of pollution.

关键词： Algae Environmental Monitoring Industry Metals, Heavy Water Pollutants, Chemical

Some Geometric Invariants of Pseudo-Spherical Evolutes in the Hyperbolic 3-Space

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Computers, Materials & Continua 2018年第12期57卷 389-415页

作者： H.S.abdel-Aziz M.Khalifa Saad A.A.abdel-salam Mathematics Department Faculty of ScienceSohag University82524SohagEgypt Mathematics Department Faculty of ScienceIslamic University of Madinah170 El-MadinahKSA

In this paper,we study the pseudo-spherical evolutes of curves in three dimensional hyperbolic *** use techniques from singularity theory to investigate the singularities of pseudo-spherical evolutes and establish some relationships between singularities of these curves and geometric invariants of curves under the action of the Lorentz ***,we defray with illustration some computational examples in support our main results.

关键词： Pseudo-spherical evolutes evolute curves hyperbolic 3-space