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First multicenter study for risk factors for hepatocellular carcinoma development in North Africa

World Journal of Hepatology 2011年第1期3卷 24-30页

作者： Olfa Bahri Sayeh Ezzikouri Nissaf Ben Alaya-Bouafif Fella Iguer abdallah essaid el feydi Hafedh Mestiri Moustapha Benazzouz Tahar Khalfallah Rajaa Afifi Latifa elkihal Salah Berkane Agnes Marchio Nabil Debzi Anne Dejean Pascal Pineau Hinda Triki Soumaya Benjelloun Laboratory of Clinical Virology Institut Pasteur of Tunis Laboratory of Viral Hepatitis Institut Pasteur of Casablanca Laboratory of Epidemiology Institut Pasteur of Tunis Laboratory of Viral Hepatitis Institut Pasteur of Algiers Department of Medicine C Ibn-Sina University Hospital Department of General Surgery Mongi Slim Hospital Department of Gastroenterology Bologhine University Hospital Bologhine 16090AlgiersAlgeria Nuclear Organization and Oncogenesis Unit INSERM U993Institut Pasteur of Paris Department of Gastroenterology Mustapha University Hospital

AIM:To assess the role of the major risk factors for hepatocellular carcinoma(HCC) development in the western part of North ***:A multicenter case control study was conducted in Tunisia,Morocco and Algeria in collaboration with Pasteur Institutes in these countries.A total of 164 patients with HCC and 250 control subjects without hepatic diseases were *** of HBsAg,anti-hepatitis C virus(HCV)and diabetes were *** and HBV genotyping were performed for anti-HCV and HBsAg positive ***:The mean age of patients was 62±10 years old for a 1.5 M:F sex *** percent of HCC patients were positive for anti-HCV and 17.9% for *** was detected in 18% of *** ratio(OR)and 95% confidence intervals(CI) were 32.0(15.8-65.0),7.2(3.2-16.1) and 8.0(3.1 -20.0)for anti-HCV,HBsAg and diabetes *** analysis indicated that the three studied factors were independent.1b HCV genotype and D HBV genotype were predominant in HCC *** was the only risk factor significantly associated with an excess of cirrhosis(90% vs 68% for all other risk factors collectively,P=0.00168).Excessive alcohol consumption was reliably established for 19(17.6%) cases among the 108 HCC patients for whom data is ***:HCV and HBV infections and diabetes are the main determinants of HCC development in North *** active surveillance and secondary prevention programs for patients with chronic hepatitis and nutrition-associated metabolic liver diseases are the most important steps to reduce the risk of HCC in the *** Berkane,Department of Gastroenterology BologhineUniversity Hospital,Bologhine 16090,Algiers。

关键词： Hepatocellular carcinoma Hepatitis B virus Hepatitis C virus Non-insulin-dependent diabetes mellitus North Africa

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Management of a Second-Trimester Abdominal Pregnancy: A Case Report and Review of the Literature

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Open Journal of Obstetrics and Gynecology 2022年第1期12卷 33-42页

作者： abdallah el Farouqi essaid Iraki Anas Boumezzough Department of Obstetrics and Gynecology Agadir Faculty of Medicine and Pharmacy University Hospital Center Agadir Morocco Surgeon Regional Hospital Center Agadir Morocco

Introduction: The abdominal pregnancy is a rare pathology that can threaten the vital prognosis of the mother. The positive diagnosis is difficult to establish. It is most often made in an acute context, leading to a high fetomaternal morbidity and mortality. Our objective is to recall the diagnostic approach and optimal management of this condition. Case report: We present the case of an abdominal pregnancy at 18 weeks of amenorrhea with partial placental abruption in a 26-year-old patient who presented with abdominal pain in emergency obstetrical department of university hospital center of Agadir. The ultrasound revealed the presence of an evolving abdominal pregnancy. The MRI allowed precisely the localization of the placenta and its relationship with the surrounding organs. A laparotomy revealed the insertion of the placenta on the right adnexa. The right adnexectomy allowed removal of the placenta without incident. Conclusion: Abdominal pregnancy is difficult to diagnose. It is essential to be well informed about the clinical and ultrasonographic semiology of this pregnancy, in order to avoid operative surprises and to ensure the appropriate treatment.

关键词： Abdominal Pregnancy Ectopic Pregnancy Advanced Ectopic Pregnancy

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