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Acta Geologica sinica(English Edition) 2021年第6期95卷 2087-2099页

作者： Osama R.sALLAM abdalla s.alshami Abd Elhadi A.ABBAs E.GUIBAL Nuclear Materials Authority CairoEgypt Institut Mines Telecom-Mines Ales Centre des Materiaux des Mines d’AlesUniversityMontpellierFrance

The Lower Carboniferous sediments at Wadi Abu El Mogheirat consist of four stratigraphic formations, from base upwards: Um Bogma, El Hashash, Magharet El Maiah and Abu Zarab formations. The most-concentrated radioactive anomalies at Wadi Abu El Mogheirat are in the middle member of the Um Bogma Formation. The gibbsitic marl in this formation shows the highest uranium contents(around 710 ppm). Gibbsitic marl and black gibbsite of the middle Um Bogma Formation show higher enrichment in Co, Cu, Mn, Ni, Pb, Zn, U, V, Ce and Th. Black gibbsite contains the highest total rare earth elements concentration, especially in terms of LREEs, while gibbsitic marl contains the highest content of HREEs. Anomalous contents of gold at Wadi Abu El Mogheirat are recorded for the first time in the gibbsitic marl(content: 10.4 ppm), black gibbsite(2.8 ppm) of the middle member of the Um Bogma Formation and in the siltstones of the El Hashash Formation(0.6 ppm). Gibbsitic marl shows the presence of uranothorite, celestite, zircon, atacamite, barite, xenotime and rutile. These characteristic demonstrate that the middle member of the Um Bogma Formation constitutes a potential source for gold. This conclusion is reinforced by the potential to exploit other metals such as Co, Cu, Mn, Ni, Pb, Zn, U, V, Th and Ce as by-products.

关键词： gibbsite rare earth elements Um Bogma

Insulin resistance as the molecular link between diabetes and Alzheimer's disease

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World Journal of Diabetes 2024年第7期15卷 1430-1447页

作者： Mona Mohamed Ibrahim abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetes mellitus(DM)and Alzheimer's disease(AD)are two major health concerns that have seen a rising prevalence *** studies have indicated a possible link between DM and an increased risk of developing ***,while primarily known for its role in regulating blood sugar,also plays a vital role in protecting brain *** resistance(IR),especially prevalent in type 2 diabetes,is believed to play a significant role in AD's *** insulin signalling becomes dysfunctional,it can negatively affect various brain functions,making individuals more susceptible to AD's defining features,such as the buildup of beta-amyloid plaques and tau protein *** research suggests that addressing insulin-related issues might help reduce or even reverse the brain changes linked to *** review aims to explore the relationship between DM and AD,with a focus on the role of *** also explores the molecular mechanisms by which IR might lead to brain changes and assesses current treatments that target *** IR's role in the connection between DM and AD offers new possibilities for treatments and highlights the importance of continued research in this interdisciplinary field.

关键词： Alzheimer's disease Insulin resistance Obesity Dementia Diabetes Metabolic syndrome

Classified VPN Network Traffic Flow Using Time Related to Artificial Neural Network

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Computers, Materials & Continua 2024年第7期80卷 819-841页

作者： saad abdalla Agaili Mohamed sefer Kurnaz Department of Electrical and Computer Engineering Altinbas UniversityIstanbul34000Turkey

VPNs are vital for safeguarding communication routes in the continually changing cybersecurity ***,increasing network attack complexity and variety require increasingly advanced algorithms to recognize and categorizeVPNnetwork *** present a novelVPNnetwork traffic flowclassificationmethod utilizing Artificial Neural Networks(ANN).This paper aims to provide a reliable system that can identify a virtual private network(VPN)traffic fromintrusion attempts,data exfiltration,and denial-of-service *** compile a broad dataset of labeled VPN traffic flows from various apps and usage ***,we create an ANN architecture that can handle encrypted communication and distinguish benign from dangerous *** effectively process and categorize encrypted packets,the neural network model has input,hidden,and output *** use advanced feature extraction approaches to improve the ANN’s classification accuracy by leveraging network traffic’s statistical and behavioral *** also use cutting-edge optimizationmethods to optimize network characteristics and *** suggested ANN-based categorization method is extensively tested and *** show the model effectively classifies VPN traffic *** also show that our ANN-based technique outperforms other approaches in precision,recall,and F1-score with 98.79%*** study improves VPN security and protects against new *** VPNtraffic flows effectively helps enterprises protect sensitive data,maintain network integrity,and respond quickly to security *** study advances network security and lays the groundwork for ANN-based cybersecurity solutions.

关键词： VPN network traffic flow ANN classification intrusion detection data exfiltration encrypted traffic feature extraction network security

Advancing diabetes management: Exploring pancreatic beta-cell restoration’s potential and challenges

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World Journal of Gastroenterology 2024年第40期30卷 4339-4353页

作者： Mona Mohamed Ibrahim abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetes mellitus,characterized by chronic hyperglycemia due to insulin deficiency or resistance,poses a significant global health *** to its pathogenesis is the dysfunction or loss of pancreatic beta cells,which are res-ponsible for insulin *** advances in beta-cell regeneration research offer promising strategies for diabetes treatment,aiming to restore endogenous insulin production and achieve glycemic *** review explores the physiological basis of beta-cell function,recent scientific advan-cements,and the challenges in translating these findings into clinical *** highlights key developments in stem cell therapy,gene editing technologies,and the identification of novel regenerative *** the potential,the field faces hurdles such as ensuring the safety and long-term efficacy of regen-erative therapies,ethical concerns around stem cell use,and the complexity of beta-cell differentiation and *** review highlights the importance of interdisciplinary collaboration,increased funding,the need for patient-centered approaches and the integration of new treatments into comprehensive care strategies to overcome these *** continued research and collab-oration,beta-cell regeneration holds the potential to revolutionize diabetes care,turning a chronic condition into a manageable or even curable disease.

关键词： Diabetes therapies Beta cell regeneration Regenerative medicine stem cell therapy Gene editing Molecular therapeutics

Advancing sandstone reservoir compressibility prediction:A correlation-driven methodology

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Petroleum Research 2024年第2期9卷 273-279页

作者： Tarek Ganat Meftah Hrairi Amr Badawy Vahid Khosravi Mohammed abdalla Department of Petroleum Chemical Engineering Sultan Qaboos UniversityP.O.Box 50Al-Khod123MuscatOman Department of Mechanical and Aerospace Engineering International Islamic University MalaysiaP.O.Box 1050728Kuala LumpurMalaysia Reservoir Engineering section Petronas Carigali SDN BHDP.O.Box 10500088Kuala LumpurMalaysia Department of Chemical and Petroleum Engineering Faculty of EngineeringTechnologyand Built EnvironmentUCSI University56000Kuala LumpurMalaysia Chemical&Petroleum Engineering United Arab Emirates UniversityP.O.Box No.15551Al AinUAE

This study presents a correlation-based approach for predicting the compressibility of sandstone reservoir *** study proposes a matrix of new empirical equations that significantly improve the precision of measuring the pore volume compressibility,with the most optimal fit of results based on a cubic polynomial *** accuracy of the calculations was validated through comparison with actual data using root mean square method,and the suggested correlations significantly enhance the precise prediction of rock compressibility in sandstone *** this study,the source of data collection is consolidated and unconsolidated sandstone from East Asia offshore ***,variations in compressibility with net overburden pressure over the course of the field's lifespan have been *** results demonstrate the application of regression analysis in establishing a network of linkages between independent and dependent *** proposed correlations for consolidated and unconsolidated sandstones offer a remarkable improvement in the accurate calculation of rock compressibility compared to traditional laboratory procedures,with an average error of 2.5%compared to 5-10%for laboratory *** approach of this study offers a cost-effective and time-efficient alternative to remarkedly enhance the overall performance of sandstone reservoirs in the oil and gas industry.

关键词： Compressibility Consolidated and unconsolidated sandstone Rock properties Rock mechanics

Mechanical performance of cold mix asphalt containing cup lump rubber as a sustainable bio-modifier

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Journal of Traffic and Transportation Engineering(English Edition) 2024年第3期11卷 424-440页

作者： syed Abdul Ghafar Muhammad Naqiuddin Mohd Warid Norhidayah Abdul Hassan Zulfiqar Ali Jattak Ashraf abdalla Mohammed Radwan Faculty of Civil Engineering Universiti Teknologi MalaysiaSkudai 81310Malaysia Department of Civil Engineering Balochistan University of Information TechnologyEngineering&Management SciencesQuettaPakistan Department of Civil Engineering Balochistan University of Engineering and TechnologyKhuzdarPakistan Department of Civil Engineering Faculty of EngineeringUniversity of TripoliTripoliLibya

The road construction industry aims to contribute to the protection of already compromised *** mix asphalt(CMA)is a measure initiated by the road industry to protect the environment and preserve *** having additional benefits,CMA has attracted little attention due to its inferior ***'s performance is enhanced using a sustainable binder bio-modifier,natural cup lump rubber(CLR)is one of *** study evaluated the tensile properties,rutting,moisture susceptibility,and adhesion properties of CLR-modified CMA(CMA-CR).The tensile property was enhanced by 26%due to CLR ***-CR had excellent rutting resistance of less than 2 mm rut depth at 10,000 load cycles,showing 70%improvement compared with conventional *** susceptibility evaluation indicated that CMA-CR had tensile strength ratio(TsR)value of 104%,satisfying the minimum 80%requirement of AAsHTO *** also retained more than 96%bitumen *** moisture damage resistance was improved by 12%and 10%in terms of TsR and stripping,*** durability results revealed that the CMA-CR mixture prevented higher mass loss,representing 14%improvement compared with conventional CMA.

关键词： Cup lump rubber Cup lump modified cold mix asphalt Moisture damage Tensile property Rutting Digital imaging

A gated recurrent unit model to predict Poisson’s ratio using deep learning

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第1期16卷 123-135页

作者： Fahd saeed Alakbari Mysara Eissa Mohyaldinn Mohammed abdalla Ayoub Ibnelwaleed A.Hussein Ali samer Muhsan syahrir Ridha Abdullah Abduljabbar salih Petroleum Engineering Department Universiti Teknologi PETRONAS32610Bandar Seri IskandarPerakMalaysia Institute of Hydrocarbon Recovery Universiti Teknologi PETRONAS32610Bandar Seri IskandarPerakMalaysia Gas Processing Center College of EngineeringQatar UniversityP.O.Box 2713DohaQatar Department of Chemical Engineering College of EngineeringQatar UniversityP.O.Box 2713DohaQatar Mechanical Engineering Department Universiti Teknologi PETRONAS32610Bandar Seri IskandarPerakMalaysia

static Poisson’s ratio(vs)is crucial for determining geomechanical properties in petroleum applications,namely sand *** models have been used to predict vs;however,the published models were limited to specific data ranges with an average absolute percentage relative error(AAPRE)of more than 10%.The published gated recurrent unit(GRU)models do not consider trend analysis to show physical *** this study,we aim to develop a GRU model using trend analysis and three inputs for predicting n s based on a broad range of data,n s(value of 0.1627-0.4492),bulk formation density(RHOB)(0.315-2.994 g/mL),compressional time(DTc)(44.43-186.9 μs/ft),and shear time(DTs)(72.9-341.2μ s/ft).The GRU model was evaluated using different approaches,including statistical error *** GRU model showed the proper trends,and the model data ranges were wider than previous *** GRU model has the largest correlation coefficient(R)of 0.967 and the lowest AAPRE,average percent relative error(APRE),root mean square error(RMsE),and standard deviation(sD)of 3.228%,1.054%,4.389,and 0.013,respectively,compared to other *** GRU model has a high accuracy for the different datasets:training,validation,testing,and the whole datasets with R and AAPRE values were 0.981 and 2.601%,0.966 and 3.274%,0.967 and 3.228%,and 0.977 and 2.861%,*** group error analyses of all inputs show that the GRU model has less than 5% AAPRE for all input ranges,which is superior to other models that have different AAPRE values of more than 10% at various ranges of inputs.

关键词： static Poisson’s ratio Deep learning Gated recurrent unit(GRU) sand control Trend analysis Geomechanical properties

Long-term outcomes of titanium-nitride-oxide coated stents and drug-eluting stents in acute coronary syndrome:A systematic review and meta-analysis

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World Journal of Cardiology 2024年第5期16卷 293-305页

作者： Muhammad Ahmed Ali Fahim Afia salman Hira Anas Khan syed Muhammad Hasan Muskan FatimaBhojani sarah Aslam Amna Zia Ul Haq Vishal Reddy Bejugam Beena Muntaha Nasir Wajiha Gul Abdul Moeed Abdelrahman s abdalla Muhammad Majid Muhammad sohaib Asghar Md Al Hasibuzzaman Department of Internal Medicine Dow University of Health SciencesKarachi 74200Pakistan Department of Internal Medicine North Central Bronx HospitalBronxNY 10467United States Department of Urology Center for Academic MedicineStanford University School of MedicinePalo AltoCA 33872United States Department of Cardiovascular Imaging Cleveland ClinicClevelandOH 44195United States Division of Nephrology and Hypertension Mayo Clinic RochesterRochesterMN 55905United States Institute of Nutrition and Food science University of DhakaDhaka 1000Bangladesh

BACKGROUND In severe cases of coronary artery disease,percutaneous coronary intervention provide promising *** stent used could be a drug-eluting stent(DEs)or a titanium-nitride-oxide coated stent(TiNOs).AIM To compare the 5-year effectiveness and safety of the two stent *** The following systematic review and meta-analysis was conducted in accordance with the preferred reporting items for systematic reviews and meta-analysis guidelines,and PubMed/MEDLINE,scopus,and Cochrane Central were searched from inception till August *** outcomes were major adverse cardiac events(MACE),cardiac death,myocardial infarction(MI),cardiac death or MI,and ischemia-driven total lesion revascularization(ID-TLR).REsULTs Four randomized controlled trials(RCT),which analyzed a sum total of 3045 patients with acute coronary syndrome(ACs)after a median follow-up time of 5 years were *** statistically insignificant,an increase in the ID-TLR was observed in patients receiving TiNOss vs *** addition,MI,cardiac death and MI,and definite stent thrombosis(DsT)were significantly decreased in the TiNOs *** analysis revealed no significant results with meta-regression presenting non-sT elevated MI(NsTEMI)as a statistically significant covariate in the outcome of *** TiNOs was found to be superior to DEs in terms of MI,cardiac death or MI,and DsT outcomes,however,the effect of the two stent types on ID-TLR and MACE was not significant.A greater number of studies are required to establish an accurate comparison of patient outcomes in TiNOs and DEs.

关键词： stents Drug-eluting Major adverse cardiac events All-cause death Meta-analysis

structure-based discovery of *** phytochemicals as potential inhibitors against Monkeypox(mpox)viral protein

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Journal of Biosafety and Biosecurity 2024年第3期6卷 157-169页

作者： Ranjan K.Mohapatra Ahmed Mahal Pranab K.Mohapatra Ashish K.sarangi snehasish Mishra Meshari A.Alsuwat Nada N.Alshehri sozan M.Abdelkhalig Mohammed Garout Mohammed Aljeldah Ahmad A.Alshehri Ahmed saif Mohammed Abdulrahman Alshahrani Ali s.Alqahtani Yahya A.Almutawif Hamza M.A.Eid Faisal M Albaqami Mohnad abdalla Ali A.Rabaan Department of Chemistry Government College of EngineeringKeonjhar 758002OdishaIndia Department of Medical Biochemical Analysis College of Health TechnologyCihan University–ErbilErbilKurdistan RegionIraq Department of Chemistry CV Raman Global UniversityBhubaneswarOdishaIndia Department of Chemistry School of Applied SciencesCenturion University of Technology and ManagementBalangirOdishaIndia school of Biotechnology Campus-11KIIT Deemed-to-be-UniversityBhubaneswar 751024OdishaIndia Clinical Laboratory sciences Department College of Applied Medical SciencesTaif UniversityAl-Taif 21974Saudi Arabia Internal Medicine Department King Khalid University Medical CityCollege of MedicineAbha 61481Saudi Arabia Department of Basic Medical sciences College of MedicineAlMaarefa UniversityRiyadhSaudi Arabia Department of Community Medicine and Health Care for Pilgrims Faculty of MedicineUmm Al-Qura UniversityMakkah 21955Saudi Arabia Department of Clinical Laboratory sciences College of Applied Medical SciencesUniversity of Hafr Al BatinHafr Al Batin 39831Saudi Arabia Department of Clinical Laboratory sciences Faculty of Applied Medical SciencesNajran UniversityNajran 61441Saudi Arabia Department of Medical Laboratory sciences Faculty of Applied Medical SciencesKing Khalid UniversityAbha 61481Saudi Arabia mDepartment of Medical Laboratories Technology College of Applied Medical SciencesTaibah UniversityMadinah 41411Saudi Arabia Biology Department College of ScienceIslamic University of MadinahMadinah 42351Saudi Arabia Pediatric Research Institute Children’s Hospital Affiliated to Shandong UniversityJinanShandong 250022China Molecular Diagnostic Laboratory Johns Hopkins Aramco HealthcareDhahran 31311Saudi Arabia College of Medicine Alfaisal UniversityRiyadh 11533Saudi Arabia Department of Public Health and Nutrition The University of HaripurHaripur 22610Pakistan

Outbreaks of Monkeypox(mpox)in over 100 non-endemic countries in 2022 represented a serious global health *** a neglected disease,mpox has become a global public health issue.A42R profilinlike protein from mpox(PDB ID:4QWO)represents a potential new lead for drug development and may interact with various synthetic and natural *** this report,the interaction of A42R profilinlike protein with six phytochemicals found in the medicinal plant Ficus religiosa(abundant in India)was *** on the predicted and compared protein–ligand binding energies,biological properties,IC_(50) values and toxicity,two compounds,kaempferol(C-1)and piperine(C-4),were *** characteristics and quantitative structure–activity relationship(QsAR)of these two compounds were determined,and molecular dynamics(MD)simulations were *** silico examination of the kaempferol(C-1)and piperine(C-4)interactions with A42R profilin-like protein gave best-pose ligandbinding energies of–6.98 and–5.57 kcal/mol,*** predicted IC_(50) of C-1 was 7.63 lM and 82 lM for *** data indicated that kaempferol and piperine are non-mutagenic,and the QsAR data revealed that piperlongumine(5.92)and piperine(5.25)had higher log P values than the other compounds *** simulations of A42R profilin-like protein in complex with C-1 and C-4 were performed to examine the stability of the ligand–protein ***/C and C-4 showed the highest affinity and activities,they may be suitable lead candidates for developing mpox therapeutic *** study should facilitate discovering and synthesizing innovative therapeutics to address other infectious diseases.

关键词： Monkeypox Mpox Phytochemical Molecular docking MD simulation ADMET QsAR

深度学习算法在锥束CT中检测和三维分割颌面骨病变的研究

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国际医学放射学杂志 2024年第1期 123-124页

作者： T.Yeshua s.Ladyzhensky A.Abu-Nasse R.abdalla-Aslan T.Boharon A.Itzhak-Pur 李彤巍

摘要目的开发自动化的深度学习算法并用于在颌面部锥形束CT(CBCT)扫描来检测和三维分割偶然发现的骨病变。方法该数据集包括82个CBCT扫描，其中41个经组

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