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Isoimperatorin alleviates acetic acid-induced colitis in rats

Asian Pacific Journal of Tropical Biomedicine 2024年第4期14卷 147-153页

作者： Saied Goodarzi Amir Hossein Abdolghaffari Behnaz Najafi Mostafa Pirali Hamedani Saeed Tavakoli Mahshad Marvi Maryam Baeeri Narguess Yassa abbas hadjiakhoondi Mohammad Abdollahi Zahra Tofighi Medicinal Plants Research Center Faculty of PharmacyTehran University of Medical SciencesTehranIran Department of Toxicology and Pharmacology Faculty of PharmacyTehran Medical SciencesIslamic Azad UniversityTehranIran Department of Pharmacognosy Faculty of PharmacyTehran University of Medical SciencesTehranIran Medicinal Plants Research Center Institute of Medicinal PlantsACECRKarajIran International Campus School of Pharmacy Tehran University of Medical SciencesTehranIran Toxicology and Diseases group The Pharmaceutical Sciences Research CenterTehran University of Medical SciencesTehranIran Department of Toxicology and Pharmacology Faculty of PharmacyTehran University of Medical SciencesTehranIran

Objective:To investigate the effect of isoimperatorin on histopathological and biochemical changes in acetic acid-induced colitis ***:Colitis was induced by intracolonic administration of acetic acid solution(4%v/v)in *** were divided into six groups including the sham group,the negative control group,the dexamethasone-treated group,and the groups treated with isoimperatorin(0.1,1,and 10 mg/kg/d by gavage).The treatments were administered for three days and then colonic status was assessed by macroscopic,histopathological,and biochemical ***:Isoimperatorin significantly alleviated colonic damage in a dose-dependent manner and improved histological changes in rats with acetic acid-induced *** also significantly reduced myeloperoxidase,TNF-α,IL-1β,and malodialdehyde ***:Isoimperatorin alleviates acetic acid-induced colitis in rats and may be a potential therapeutic agent for the treatment of colitis.

关键词： Isoimperatorin Inflammatory bowel disease Acetic acid Colitis TNF-α IL-1β

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Larvicidal activity of essential oil and methanol extract of Nepeta menthoides against malaria vector Anopheles stephensi

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Asian Pacific Journal of Tropical Medicine 2012年第12期5卷 962-965页

作者： Khanavi Mahnaz Fallah Alireza Vatandoost Hassan Sedaghat Mahdi Abai Mohammad Reza hadjiakhoondi abbas Departments of Pharmacognosy Faculty of Pharmacy and Traditional Iranian Medicine and Pharmacy Research CenterTehran University of Medical SciencesTehranIran Department of Medical Entomology and Vector Control School of Public HealthTehran University of Medical SciencesTehranIran Departments of Pharmacognosy Faculty of Pharmacy and Medicinal Plants Research CenterTehran University of Medical SciencesTehranIran

Objective:To investigate the larvicidai activity of essential oil and methanol extract of the Nepeta menthoides（***） against main malaria vector,Anopheles stephensi（An. stephensi）.Methods:The essential oil of planl was obtained by Clevenger type apparatus and the methanol extract was supplied with Percolation method,larvicidai activity was tested by WHO *** five fourth-instar larvae of *** were used in the larvicidai assay and four replicates were tested for each *** different concentrations of the oil and extract were tested for calculation of LC50 and LC50 ***:The LC50 and LC90 values were determined by probit ***50 was 69.5 and 234.3 ppm and LC50 was 175.5 and 419.9 ppm for the extract and essential oil ***:According to the results of this study methanolic extract of plant exhibited more larvicidai activity than essential *** could be useful for investigation of new natural larvicidai compounds.

关键词： Larvicidal activity Anopheles stephensi Nepeta menthoides Methanol extract Essential oil

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Heat transfer analysis in particle-laden flows using the immersed boundary method

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Particuology 2024年第7期90卷 394-403页

作者： Ali abbas Zaidi Department of Mechanical Engineering University of Manitoba75A Chancellors CircleWinnipegR3T 5V6Canada

This paper investigates an efficient immersed boundary method(IBM)for multiple-core CPU machines with local grid refinement for the calculation of heat transfer between fluids and finite-sized *** fluid momentum equations are solved by using the fractional step method,while the energy equation is solved by employing the second-order Adams-Bashforth *** efficient load balancing between the CPU cores,the coupling between particles and fluid is obtained by applying the body force in the fluid equations,which depends on the solid volume fraction of particles contained in each grid cell,and then by linearly interpolating the particle temperature and velocity on the fluid grid cell(in place of the delta function commonly used in literature).Several test cases from the literature are studied,and good agreement is observed between the simulation results and the ***,a scaling study on multiple core machines is performed,demonstrating the proposed IBM's capabilities for a significant reduction in processing time.

关键词： Heat transfer Immersed boundary method Particle resolved direct numerical simulations Fluid solid interactions

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Astrodaucus persicus as a new source of bioinsectisides against malaria vector, Anopheles stephensi

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Asian Pacific Journal of Tropical Medicine 2017年第9期10卷 896-899页

作者： Saied Goodarzi Hassan Vatandoost Mohammad Reza Abai Saeed Tavakoli Amir Hatamian Yousef Ajani abbas hadjiakhoondi Narguess Yassa Zahra Tofighi Medicinal Plants Research Center Faculty of Pharmacy Tehran University of Medical Sciences Department of Medical Entomology and Vector Control School of Public Health Tehran University of Medical Sciences Department of Pharmacognosy Faculty of Pharmacy Tehran University of Medical Sciences

Objective: To determine the larvicidal activities of petroleum ether, chloroform, ethyl acetate and methanol fractions of roots and fruits extracts of Astrodaucus persicus from Apiaceae family against malaria vector, Anopheles stephensi(An. stephensi).Methods: Twenty five third instar larvae of An. stephensi were exposed to various concentrations(10–160 g/L) of fractions and were assayed according to World Health Organization protocol. The larval mortality was calculated after 24 h ***: Among tested fractions, the highest larvicidal efficacy was observed from ethyl acetate fraction of fruits extract with 50% and 90% mortality values(LC_(50) and LC_(90)) of34.49 g/L and 108.61 g/L, respectively. Chloroform fraction of fruits extract was the second larvicidal sample with LC_(50) of 45.11 g/L and LC_(90) of 139.36 g/L. Petroleum ether fractions of fruits and roots and methanol fraction of fruits showed moderate toxicity against An. ***: Astrodaucus persicus is a potential source of valuable and natural larvicidal compounds against malaria vector, An. stephensi and can be used in mosquitoes control programs as an alternative to synthetic insecticides.

关键词： Astrodaucus persicus 疟疾向量蚊子控制 Bioinsecticide 疟蚊属 stephensi 幼虫

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Phytochemistry and larvicidal activity of Eucalyptus camaldulensis against malaria vector,Anopheles stephensi

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Asian Pacific Journal of Tropical Medicine 2010年第11期3卷 841-845页

作者： Sedaghat Mohamad Medhi Sanei Dehkordi Ali Reza Khnavi Mahnaz Abai Mohammad Reza hadjiakhoondi abbas Mohtarami Fatemeh Vatandoost Hassan Department of Medical Entomology and Vector Control School of Public HealthTehran University of Medical SciencesTehranIran Departments of Pharmacognosy Faculty of PharmacologyTehran University of Medical SciencesTehranIran

Objective:To determine phytochemistry and larvicidal activity of Eucalyptus eamaldulensis against Anopheles ***:The chemical compositions of the leaf essential oils were analyzed using gas chromatography/mass spectrometry（GC/MS）.The larvicidal activity of essential oils and extract of leaf were tested against 4th instar larvae of laboratory-reared Anopheles ***:GC/MS analyses identified the presence of 28 compounds corresponding to 99.60%of the total *** main constituents in the leaf essential oil were 1,8-cineole（69.46%）,γ-Terpinene（15.10%）,α-Pinene（5.47%） and Globulol（2%）.The leaf extract and volatile oil exerted significant larvicidal activity with LC50 values of 89.85 and 397.75 ppm,*** dose-response relationships were established with the highest dose of 320 ppm essential oil extract resulted almost 100%mortality in the ***:The larvicidal properties suggest that the essential oil of plant is a potential source of valuable larvicidal compounds against malaria vector and can be used as an alternative to synthetic insecticides.

关键词： Eucalyptus camaldulensis Essential oil Larvicide Anopheles stephensi

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Feedback Mechanism-driven Mutation Reptile Search Algorithm for Optimizing Interpolation Developable Surfaces

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Journal of Bionic Engineering 2024年第1期21卷 527-571页

作者： Gang Hu Jiao Wang Xiaoni Zhu Muhammad abbas Department of Applied Mathematics Xi'an University of TechnologyXi'an 710054China School of Mechanical and Precision Instrument Engineering Xi'an University of TechnologyXi'an 710048China Department of Mathematics University of SargodhaSargodha 40100Pakistan

Curvature lines are special and important curves on *** is of great significance to construct developable surface interpolated on curvature lines in engineering *** this paper,the shape optimization of generalized cubic ball developable surface interpolated on the curvature line is studied by using the improved reptile search ***,based on the curvature line of generalized cubic ball curve with shape adjustable,this paper gives the construction method of SGC-Ball developable surface interpolated on the ***,the feedback mechanism,adaptive parameters and mutation strategy are introduced into the reptile search algorithm,and the Feedback mechanism-driven improved reptile search algorithm effectively improves the solving *** IEEE congress on evolutionary computation 2014,2017,2019 and four engineering design problems,the feedback mechanism-driven improved reptile search algorithm is compared with other representative methods,and the result indicates that the solution performance of the feedback mechanism-driven improved reptile search algorithm is *** last,taking the minimum energy as the evaluation index,the shape optimization model of SGC-Ball interpolation developable surface is *** developable surface with the minimum energy is achieved with the help of the feedback mechanism-driven improved reptile search algorithm,and the comparison experiment verifies the superiority of the feedback mechanism-driven improved reptile search algorithm for the shape optimization problem.

关键词： Reptile search algorithm Feedback mechanism Adaptive parameter Mutation strategy SGC-Ball interpolation developable surface Shape optimization

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A Stochastic Model to Assess the Epidemiological Impact of Vaccine Booster Doses on COVID-19 and Viral Hepatitis B Co-Dynamics with Real Data

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Computer Modeling in Engineering & Sciences 2024年第3期138卷 2973-3012页

作者： Andrew Omame Mujahid abbas Dumitru Baleanu Department of Mathematics Federal University of TechnologyOwerri460114Nigeria Abdus Salam School of Mathematical Sciences Government College UniversityLahore54000Pakistan Department of Mathematics Government College UniversityLahore54000Pakistan Department of Computer Science and Mathematics Labanese American UniversityBeirutLebanon Institute of Space Sciences Magurele-BucharestRomania Department of Medical Research China Medical University HospitalChina Medical UniversityTaichung40402Taiwan

A patient co-infected with COVID-19 and viral hepatitis B can be atmore risk of severe complications than the one infected with a single *** study develops a comprehensive stochastic model to assess the epidemiological impact of vaccine booster doses on the co-dynamics of viral hepatitis B and *** model is fitted to real COVID-19 data from *** proposed model incorporates logistic growth and saturated incidence *** analyses using the tools of stochastic calculus,are performed to study appropriate conditions for the existence of unique global solutions,stationary distribution in the sense of ergodicity and disease *** stochastic threshold estimated from the data fitting is given by:R_(0)^(S)=*** assessments are implemented to illustrate the impact of double-dose vaccination and saturated incidence functions on the dynamics of both *** effects of stochastic white noise intensities are also highlighted.

关键词： Viral hepatitis B COVID-19 stochastic model extinction ergodicity real data

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Seismic performance evaluation of hybrid coupled shear wall system with shear and flexural fuse-type steel coupling beams

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 691-712页

作者： Zahra Ramezandoust abbas Tajaddini Panam Zarfam Department of Civil Engineering Science and Research branchIslamic Azad UniversityTehran 14778-93855Iran Department of Civil Engineering Karaj BranchIslamic Azad UniversityKaraj 31485-313Iran

Replaceable flexural and shear fuse-type coupling beams are used in hybrid coupled shear wall(HCSW)systems,enabling concrete buildings to be promptly recovered after severe *** study aimed to analytically evaluate the seismic behavior of flexural and shear fuse beams situated in short-,medium-and high-rise RC buildings that have *** building groups hypothetically located in a high seismic hazard zone were studied.A series of 2D nonlinear time history analyses was accomplished in OpenSees,using the ground motion records scaled at the design basis earthquake *** was found that the effectiveness of fuses in HCSWs depends on various factors such as size and scale of the building,allowable rotation value,inter-story drift ratio,residual drift quantity,energy dissipation value of the fuses,*** results show that shear fuses better meet the requirements of rotations and *** contrast,flexural fuses dissipate more energy,but their sectional stiffness should increase to meet other *** was concluded that adoption of proper fuses depends on the overall scale of the building and on how associated factors are considered.

关键词： hybrid coupled shear wall steel fuse coupling beam shear and flexural fuse nonlinear dynamic analysis seismic performance

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Predicting density log from well log using machine learning techniques and heuristic optimization algorithm:A comparative study

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Petroleum Research 2024年第2期9卷 176-192页

作者： Mehdi Rahmati Ghasem Zargar abbas Ayatizadeh Tanha National Iranian Drilling Company Well Logging DepartmentAhwazIran Faculty Member of Petroleum University of Technology Iran Department of Petroleum Engineering Tarbiat Modares UniversityTehranIran

In the petroleum industry,the analysis of petrophysical parameters is critical for efficient reservoir management,production optimization,development strategies,and accurate hydrocarbon reserve *** recent years,the integration of machine learning methodologies has revolutionized the field,addressing challenges in geology,geophysics,and petroleum engineering,even when confronted with limited or imperfect *** study focuses on the prediction of density logs,a pivotal factor in evaluating reservoir hydrocarbon *** is important to note that during well logging operations,log data for specific depths of interest may be missing or incorrect,presenting a significant *** tackle this issue,we employed the Adaptive Neuro-Fuzzy Inference System(ANFIS)and Artificial Neural Networks(ANN)in combination with advanced optimization algorithms,including Particle Swarm Optimization(PSO),Imperialist Competitive Algorithms(ICA),and Genetic Algorithms(GA).These methods exhibit promising performance in predicting density logs from gamma-ray,neutron,sonic,and photoelectric log ***,our results highlight that the Genetic Algorithms-based Artificial Neural Network(GA-ANN)approach outperforms all other methods,achieving an impressive Mean Squared Error(MSE)of *** comparison,ANFIS records an MSE of 0.0015,ICA-ANN 0.0090,PSO-ANN 0.0093,and ANN 0.0183.

关键词： Density log Machine learning approaches Artificial neural networks(ANN) Adaptive neuro-fuzzy inference system(ANFIS) Optimization algorithm

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CRX-527 as a candidate adjuvant in a recombinant BCG-based malaria vaccine

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Asian Pacific Journal of Tropical Biomedicine 2024年第1期14卷 1-7页

作者： Nor Munirah Zakaria Muhammad Adamu abbas Rapeah Suppian School of Health Sciences Universiti Sains MalaysiaHealth Campus16150 Kubang KerianKota BharuKelantanMalaysia Department of Medical Microbiology and Parasitology College of Health SciencesBayero University KanoP.M.B.3011BUKKano Nigeria

Objective:To investigate the role of CRX-527,a Toll-like receptor 4 agonist,as the possible adjuvant for recombinant Mycobacterium bovis Bacillus Calmette-Guerin expressing merozoite surface protein 1C(BCG-MSP-1C).Methods:The mice were immunized with BCG and BCG-MSP-1C in the presence and absence of *** untreated mice(injected with PBS-T80 only)were the negative *** ability of CRX-527 to enhance IgG and its subclasses,as well as IL-4 and IFN-γproduction in the serum and spleen supernatant was evaluated using ***:Mice immunized with BCG-MSP-1C exhibited the highest production of IgGs,IL-4 and IFN-γafter third *** addition,CRX-527 further promoted the production of total IgG and IgG subclasses as well as IFN-γand IL-4 in the serum and splenocytes of immunized ***:CRX-527 has the potential as an adjuvant candidate for the candidate *** study is needed to verify appropriate dosage for immunization and its efficacy.

关键词： CRX-527 BCG BCG-MSP-1C TLR-4 agonists Cytokine IgG Malaria

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