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Histogram Matched Chest X-Rays based Tuberculosis Detection Using CNN

Computer Systems Science & Engineering 2023年第1期44卷 81-97页

作者： Joe Louis Paul Ignatius Sasirekha Selvakumar Kavin Gabriel Joe Louis Paul aadhithya b.kailash S.Keertivaas S.A.J.Akarvin Raja Prajan Department of Information Technology Sri Sivasubramaniya Nadar College of EngineeringRajiv Gandhi Salai(OMR)KalavakkamChennai603110Tamil NaduIndia Gullas College of Medicine-University of Visayas BaniladMandaue City6014CebuPhilippines

Tuberculosis(Tb)is a severe infection that mostly affects the lungs and kills millions of people’s lives every *** can be diagnosed using chest X-rays(CXR)and data-driven deep learning(DL)*** of its better automated feature extraction capability,convolutional neural net-works(CNNs)trained on natural images are particularly effective in image cate-gorization.A combination of 3001 normal and 3001 Tb CXR images was gathered for this study from different accessible public *** different deep CNNs(Resnet50,Resnet101,Resnet152,InceptionV3,VGG16,VGG19,DenseNet121,DenseNet169,DenseNet201,MobileNet)are trained and tested for identifying Tb and normal *** study presents a deep CNN approach based on histogram matched CXR images that does not require object segmenta-tion of interest,and this coupled methodology of histogram matching with the CXRs improves the accuracy and detection performance of CNN models for Tb ***,this research contains two separate experiments that used CXR images with and without histogram matching to classify Tb and non-Tb CXRs using deep *** was able to accurately detect Tb from CXR images using pre-processing,data augmentation,and deep CNN *** histogram matching the best accuracy,sensitivity,specificity,precision and F1-score in the detection of Tb using CXR images among ten models are 99.25%,99.48%,99.52%,99.48%and 99.22%*** histogram matching the best accuracy,sensitivity,specificity,precision and F1-score are 99.58%,99.82%,99.67%,99.65%and 99.56%*** proposed meth-odology,which has cutting-edge performance,will be useful in computer-assisted Tb diagnosis and aids in minimizing irregularities in Tb detection in developing countries.

关键词： Tuberculosis detection chest x-ray(CXR) convolutional neural networks(CNNs) transfer learning histogram matching

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Silicon and plant nutrition—dynamics,mechanisms of transport and role of silicon solubilizer microbiomes in sustainable agriculture:A review

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Pedosphere 2023年第4期33卷 534-555页

作者： barkha SHARMA kailash Chand KUMAWAT Shalini TIWARI Ajay KUMAR Rouf Ahmad DAR Ummed SINGH Massimiliano CARDINALE Department of Microbiology G.B.Pant University of Agriculture&TechnologyPantnagarUttarakhand 263145(India) Department of Industrial Microbiology Jacob Institute of Biotechnology and BioengineeringSam Higginbottom University of AgricultureTechnology and Sciences(SHUATS)PrayagrajUttar Pradesh 211007(India) College of Agriculture Agriculture UniversityJodhpurBaytuBarmerRajasthan 344034(India) Department of biological and Environmental Sciences and Technologies-DiSTebA University of SalentoSP6 Lecce-MonteroniLecce I-73100(Italy)

Silicon(Si)is the second most abundant element in the Earth’s crust and has numerous roles in both soils and plants,although it is inaccessible to plants in its native state(insoluble silicate minerals).This inaccessibility can lead to insufficiency,which induces anomalies in plant growth and ***,Si alleviates various biotic and abiotic stresses in plants by enhancing tolerance mechanisms at different stages of uptake/deposition as a monosilicic *** utilization of conventional Si fertilizers to boost agricultural productivity in an attempt to meet the world’s ever-increasing food demand may result in surface and groundwater pollution,waterway eutrophication,soil fertility depletion,and accumulation of hazardous elements such as arsenic in *** addressing the drawbacks of chemical fertilizers,this review emphasizes an environmentally friendly alternative,namely,Si-solubilizing microorganisms(SSMs),as bioinoculants to liberate soluble Si and thus making it available to plants.A deep understanding of recent advances in the functional diversity,colonization patterns,modes of action,role in biogeochemical cycling,and plant stress tolerance of SSMs and their implementation in Si-based agrowaste management through the fabrication of nanoparticles,could help to establish a reliable tool for economically and environmentally sustainable *** this perspective,in this review,we comprehensively summarize the latest methodologies for the isolation,screening,and characterization of SSMs and Si solubilization mechanisms,including ligands(divalent cations),acids(inorganic and organic),alkali(nucleophilic attack),extracellular polysaccharides,and factors affecting them,as well as Si-mediated regulation of gene expression involved in Si uptake,transportation,and *** have critically revised the role of SSMs according to the current *** contributions of SSMs to biofertilization are still being explored;hence,we also

关键词： agrowaste management biofertilizer bioinoculant monosilicic acid plant stress silicon-solubilizing microorganism

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Antiplasmodial activity of silver nanoparticles: A novel green synthesis approach

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Asian Pacific Journal of Tropical biomedicine 2018年第5期8卷 268-272页

作者： Madhur Sardana Varnika Agarwal Akansha Pant Vinita Kapoor kailash C.Pandey Sanjay Kumar Department of Chemistry Sri Venkateswara College University of Delhi National Institute of Malaria Research ICMR Department of biochemistry National Institute for Research in Environmental HealthICMR

Objective:To synthesize silver nanoparticles using silver nitrate by a green technique which involves different compositions of aqueous leaf extracts of Azadirachta indica(neem)and Ocimum sanctum(tulsi).Methods:Their shape and size were determined using transmission electron microscopy and UV-visible *** antiplasmodial activity was studied using the malarial parasite strain(Plasmodium falciparum,3D7).The parasite strain(3D7)was collected and revived in vitro using Trager and Jensen method in RPMI 1640 medium for *** maximal effective concentration values were calculated by nonlinear regression ***:Transmission electron microscopy results confirmed the formation of silver nanoparticles with size ranging from 4.74-39.32 nm and their size differs by varying the concentrations from 20%to 100%of neem extract in neem and tulsi *** was observed that samples b and C showed half maximum effective concentration of about 0.3μ***:It can be easily established that the aqueous leaf extracts of neem and tulsi in combination can be a good source for synthesis of silver nanoparticles with small size possessing appreciable antiplasmodial activity.

关键词： Malaria Antiplasmodial activity Silver nanoparticles Green synthesis Azadirachta indica Ocimum sanctum

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Plant diversity of the Kangchenjunga Landscape, Eastern Himalayas

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Plant Diversity 2019年第3期41卷 153-165页

作者： Pratikshya Kandel Nakul Chettri Ram P.Chaudhary Hemant Kumar badola kailash S.Gaira Sonam Wangchuk Namgay bidha Yadav Uprety Eklabya Sharma International Centre for Integrated Mountain Development Kathmandu Nepal Research Centre for Applied Science and Technology (RECAST) Kathmandu Nepal G b Pant National Institute of Himalayan Environment and Sustainable Development (GbPNIHESD) Sikkim India Nature Conservation Division Department of Forest and Park Services Thimphu Bhutan

The Kangchenjunga Landscape (KL) in the Eastern Himalayas is a transboundary complex shared by bhutan, India, and Nepal. It forms a part of the ‘Himalayan biodiversity Hotspot’ and is one of the biologically richest landscapes in the Eastern Himalayas. In this paper, we use secondary information to review and consolidate the knowledge on the flora of the KL. We reviewed 215 journal articles, analysed the history of publications on the flora of the KL, their publication pattern in terms of temporal and spatial distribution and key research areas. Our review shows that the landscape has a long history of botanical research that dates back to the 1840s and progressed remarkably after the 1980s. Most of the studies have been carried out in India, followed by Nepal and bhutan. The majority of these have been vegetation surveys, followed by research on ethnobotanical aspects and Non-Timber Forest Products (NTFPs). This paper describes the forest types and characteristic species of the KL and details the species richness, diversity and dominant families of seed plants. A total of 5198 species of seed plants belonging to 1548 genera and 216 families have been recorded from the landscape, including 3860 dicots, 1315 monocots and 23 gymnosperms. Among families, Orchidaceae is the most diversely represented family in terms of species richness. This paper also draws attention to the threatened and endemic flora of the KL, including 44 species that are threatened at national and global level and 182 species that are endemic. Finally, the paper reviews the major challenges facing the KL, the conservation efforts and practices that are currently in place and recommends systematic and comprehensive floral surveys, particularly long-term data collection and monitoring and transboundary collaboration, to address the existing knowledge gaps on floral diversity of the KL.

关键词： Floral diversity Transboundary landscape Nepal India bhutan biodiversity

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Characterization of chickpea germplasm conserved in the Indian National Genebank and development of a core set using qualitative and quantitative trait data

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The Crop Journal 2016年第5期4卷 417-424页

作者： Sunil Archak Rishi K.Tyagi P.N.Harer L.b.Mahase Neeta Singh Om P.Dahiya M.Abdul Nizar Mohar Singh Vrushali Tilekar Vikas Kumar Manoranjan Dutta Narendra P.Singh kailash C.bansal ICAR-National bureau of Plant Genetic Resources Pulses Improvement Project Mahatma Phule Krishi Vidyapeeth ICAR-National bureau of Plant Genetic Resources Regional Station ICAR-Indian Institute of Pulse Research

Chickpea is the third most important pulse crop as a source of dietary protein. Ever-increasing demand in Asian countries calls for breeding superior desi-type varieties, in turn necessitating the availability of characterized germplasm to breeders. The Indian National Genebank,located at the National bureau of Plant Genetic Resources, New Delhi, conserves 14,651 accessions of chickpea. The entire set was characterized in a single large-scale *** variation was observed for eight quantitative and 12 qualitative agro-morphological traits. Allelic richness procedure was employed to assemble a core set comprising 1103 accessions, 70.0% of which were of Indian origin. Comparable values of total variation explained by the first three principal components in the entire collection(51.1%) and the core(52.4%)together with conservation of nine pairwise r values among quantitative traits in the core collection and a coincidence rate around 99.7% indicated that the chickpea core was indeed an excellent representation of the entire chickpea collection in the National Genebank. The chickpea core exhibited greater diversity than the entire collection in agro-morphological traits, as assessed by higher variance and Shannon–Weaver diversity indices, indicating that the chickpea core maximized the phenotypic diversity available in the Indian chickpea germplasm. The chickpea core, comprising mainly indigenous desi genotypes, is expected to be an excellent resource for chickpea breeders. Information on the chickpea core can be accessed at http://***/pgrportal.

关键词： Cicer arietinum Chickpea germplasm Indian National Genebank Agro-morphological variation Chickpea core

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Gas Sensing Mechanism of Metal Oxide Doped PANi Composites

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材料科学与工程（中英文b版） 2013年第5期3卷 310-313页

作者： kailash R. Nemade Sandeep A. Waghuley Department of Physics Sant Gadge Baba Amravati University Amravati 444 602 India

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A Study on Elite Mango Genotypes in Odisha—An Avenue for Crop Improvement

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Journal of Agricultural Science and Technology(b) 2016年第4期6卷 269-273页

作者： Suvalaxmi Palei basant Kumar Das kailash Chandra Mohapatra Dilip Kumar Dash Department o f Fruit Science and Horticulture Technology Orissa University o f Agriculture and Technology BhubaneswarOdisha-751003 India

A study was carried out among the local mango types in Odisha to explore their genetic variations for further utilization in crop improvement, as the genetic diversity serves as a way for the population to adopt the changing edapho-climatic condition. From 17 districts of Odisha, a total of 548 seedling trees were observed, but only 30 mango elites were selected on the basis of organoleptic test for taste, flavor and aroma. Different physico-chemical characters, like fruit size, shape, colour, flavour, aroma and other characteristics, varied widely among these genotypes. The results of the study with respect to 30 numbers of local mango genotypes revealed that the maximum individual fruit weight (510 g) and pulp percentage (78.4%) was recorded in Kali. The other desirable traits of the minimum stone percentage (5.9%) and the maximum pulp to stone ratio (12.5:1) was observed in Nakei. The minimum peel percentage (10.0%) and the maximum total soluble solid (TSS) percentage (26%) was recorded in the fruits of Mitha and Lori, respectively. Attractive fruit skin colour was observed in the genotypes Nakei and belua (yellowish), followed by Sundari (yellow with orange tinge) and Kadalia (greenish yellow). but in case of check mango cultivars Amrapali and Mallika, desirable traits, like the maximum TSS, pulp percentage, pulp to stone ratio and the minimum stone percentage was exhibited by Amrapali, whereas Mallika had the maximum fruit weight. The shape and skin colour are neither attractive nor preferred in both the commercial cultivars, so above cited eye catchy traits can be incorporated into these two superior mango genotypes from the local genotypes to meet the market demand and export potential.

关键词： Elite genotypes mango crop improvement

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Chronic Dietary Administration of 2-Deoxy-D-Glucose Does Not Compromise Neurobehavioral Functions at Tumor Preventive Doses in Mice

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Journal of behavioral and brain Science 2015年第9期5卷 381-393页

作者： Saurabh Singh Mayank Kumar kailash Manda Seenu Haridas Anant Narayan bhatt Daman Saluja bilikere S. Dwarakanath Division of Radiation biosciences Institute of Nuclear Medicine and Allied Sciences Delhi India Medical biotechnology Laboratory Dr. B.R. Ambedkar Center for Biomedical Research University of Delhi Delhi India

beneficial effects of dietary energy restriction (DER), including extension of life-span, reduction in cancer risk, anti-cancer effects and decrease in age related neurodegenerative diseases have been well established. Given that DER is difficult to implement in humans due to practical constraints, development of energy restriction mimetics (ERMs) is considered as a suitable alternative. Our recent studies have established the anti-tumor effects of the dietary administration of the glycolytic inhibitor 2-deoxy-D-glucose, a potential ERM, an alternative to DER;without any adverse effects on general physiology. Since functioning of the brain is critically dependent on glucose, we investigated the effects of chronic dietary 2-DG administration on the behavioural outcome in mice. Our findings based on a battery of neuro-behavioural tests clearly suggest that the chronic dietary administration of 2-DG that appreciably impairs the process of tumorigenesis has no adverse effect on the cognitive, affective and sensory-motor functions. Together with the maintenance of normal physiology reported by us earlier, these observations strengthen the potential of dietary 2-DG as a safe cancer preventive strategy.

关键词： Glycolysis Energy Restriction Mimetics (ERMs) 2-Deoxy-D-Glucose (2-DG) Tumor Prevention Neuro-behaviour

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豚鼠脊髓损伤模型早期骨代谢指标的改变

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复旦学报（医学版） 2002年第5期29卷 352-353页

作者：凯拉什李泽兵复旦大学附属中山医院康复科上海200032

目的　观察豚鼠脊髓损伤 (SCI)模型的骨代谢生化指标 ,骨密度骨量和形态学变化。方法　将 2 3只豚鼠分为实验组 (A组 )及正常对照组 (b组 ) ,3～ 4月龄 ,体重 4 2 7～ 710 g。A组人工脊髓损伤后 2周测bMD、血清bALP和尿Pyd/Cr,Ca/Cr,并... 详细信息

目的　观察豚鼠脊髓损伤 (SCI)模型的骨代谢生化指标 ,骨密度骨量和形态学变化。方法　将 2 3只豚鼠分为实验组 (A组 )及正常对照组 (b组 ) ,3～ 4月龄 ,体重 4 2 7～ 710 g。A组人工脊髓损伤后 2周测bMD、血清bALP和尿Pyd/Cr,Ca/Cr,并制备胫骨骺病理切片及测胫骨干重、灰重 ,采用SPSS软件作秩和检验和t检验 (P bALP减少 (bMD及干重 (P >0 .0 5 )无明显变化。结论　脊髓损伤后早期骨吸收明显增加。

关键词：脊髓损伤骨代谢指标骨吸收废用性骨质疏松

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