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国外地质与勘测 1994年第1期 24-26页

作者： aa.,ta 夏克文

Enhancing prognostic accuracy in predicting rectal neuroendocrine neoplasms

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World Journal of Gastroenterology 2024年第37期30卷 4087-4089页

作者： Renin Peter aa.Raj Abdulqadir J Nashwan Department of Medicine Aston Medical SchoolBirmingham B47ETUnited Kingdom Department of Nursing&Midwifery Research Hamad Medical CorporationDoha 3050Qatar

The recently published retrospective study introduces the GATIS score,a new predictive model for rectal neuroendocrine *** analyzing data from a large Chinese multicenter cohort,the study shows that the GATIS score,incor-porating tumor grade,T stage,tumor size,age,and prognostic nutritional index,demonstrates superior predictive power for overall survival and progression-free survival compared to traditional World Health Organization grade and tumor,nodes and metastases staging *** editorial aims to discuss the impor-tance of the GATIS score,its potential impact on clinical practice,and the strengths and limitations of the ***,it explores the significance,methodology,and clinical implications of these findings.

关键词： Rectal neuroendocrine neoplasm Nomogram Random forest Prognosis Overall survival Progression-free survival

Graphene oxide-lithium-ion batteries:inauguration of an era in energy storage technology

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Clean Energy 2024年第3期8卷 194-205页

作者： Yachana Mishra Aditi Chattaraj Alaa.aa.Aljabali Mohamed El-tanani Murtaza M.tambuwala Vijay Mishra School of Bioengineering and Biosciences Lovely Professional UniversityPhagwara(Punjab)-144411India Department of Pharmaceutics&Pharmaceutical Technology Yarmouk UniversityIrbidJordan College of Pharmacy Ras Al Khaimah Medical and Health Sciences UniversityUAE Lincoln Medical School University of LincolnBrayford Pool CampusLincoln LN67TSEnglandUK School of Pharmaceutical Sciences Lovely Professional UniversityPhagwara(Punjab)-144411India

A significant driving force behind the brisk research on rechargeable batteries,particularly lithium-ion batteries(LiBs)in high-performance applications,is the development of portable devices and electric ***-based materials,which have finite specific capacity,make up the anodes of *** attempts are being made to produce novel nanostructured composite anode materials for LiBs that display cycle stability that is superior to that of graphite using graphene ***,using significant amounts of waste graphene oxide from used LiBs represents a fantastic opportunity to engage in waste management and circular *** review outlines recent studies,developments and the current advancement of graphene oxide-based LiBs,including preparation of graphene oxide and utilization in LiBs,particularly from the perspective of energy storage technology,which has drawn more and more attention to creating high-performance electrode systems.

关键词： lithium-ion batteries graphene oxide energy storage technology waste management clean energy

targeting cAMP in D1-MSNs in the nucleus accumbens, a new rapid antidepressant strategy

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Acta Pharmaceutica Sinica B 2024年第2期14卷 667-681页

作者： Yue Zhang Jingwen Gao Na Li Peng Xu Shimeng Qu Jinqian Cheng Mingrui Wang Xueru Li Yaheng Song Fan Xiao Xinyu Yang Jihong Liu Hao Hong Ronghao Mu Xiaotian Li Youmei Wang Hui Xu Yuan Xie Tianming Gao Guangji Wang Jiye aa Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics State Key Laboratory of Natural MedicinesResearch Unit of PK-PD Based Bioactive Components and Pharmacodynamic Target Discovery of Natural Medicine of Chinese Academy of Medical SciencesChina Pharmaceutical UniversityNanjing 210009China Key Laboratory of Drug Monitoring and Control Drug Intelligence and Forensic CenterMinistry of Public SecurityBeijing 100193China School of Pharmacy China Pharmaceutical UniversityNanjing 211198China School of Foreign Languages China Pharmaceutical UniversityNanjing 211198China Department of Neurobiology School of Basic Medical SciencesSouthern Medical UniversityGuangzhou 510515China Department of Pharmacology China Pharmaceutical UniversityNanjing 211198China School of Pharmaceutical Sciences Zhengzhou UniversityZhengzhou 450001China

Studies have suggested that the nucleus accumbens(NAc)is implicated in the pathophysiology of major depression;however,the regulatory strategy that targets the NAc to achieve an exclusive and outstanding anti-depression benefit has not been ***,we identified a specific reduction of cyclic adenosine monophosphate(cAMP)in the subset of dopamine D1 receptor medium spiny neurons(D1-MSNs)in the NAc that promoted stress susceptibility,while the stimulation of cAMP production in NAc D1-MSNs efficiently rescued depression-like *** treatment enhanced cAMP both in D1-MSNs and dopamine D2 receptor medium spiny neurons(D2-MSNs)of depressed mice,however,the rapid antidepressant effect of ketamine solely depended on elevating cAMP in NAc *** discovered that a higher dose of crocin markedly increased cAMP in the NAc and consistently relieved depression 24 h after oral administration,but not a lower *** fast onset property of crocin was verified through multicenter ***,crocin specifically targeted at D1-MSN cAMP signaling in the NAc to relieve depression and had no effect on *** findings characterize a new strategy to achieve an exclusive and outstanding anti-depression benefit by elevating cAMP in D1-MSNs in the NAc,and provide a potential rapid antidepressant drug candidate,crocin.

关键词： CAMP Nucleus accumbens Depression D1-MSN D2-MSN

Pattern of intestinal helminth infections among school children in an urban community in Ibadan,Nigeria

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Asian Pacific Journal of Tropical Medicine 2008年第3期1卷 42-47页

作者： Fatiregun aa.Oluwatoba OA Department of Epidemiology Medical Statistics and Environmental HealthFaculty of Public HealthCollege of MedicineUniversity of IbadanIbadanNigeria

Despite a substantial reduction in the incidence and prevalence of parasitic diseases in the industrialized world, they continue to be an important public health problem in many developing African countries,including Nigeria. However,estimates of the prevalence of such infections among school age children,who bear the greatest health burden due to these diseases,are hard to come *** objective of this study was therefore to determine the prevalence and type of intestinal helminth infections among primary school *** study was cross-sectional in *** participants included 266 pupils recruited from three government primary schools in the Mokola area of Ibadan,*** pupils were interviewed and their stool samples examined for eggs of common *** mean age of the pupils was 9.8±2.6 years,and 128(48.1%) were *** pupils(7.1%) had intestinal helminth *** lumbricoides was found in 17 pupils(6. 4%) and was the most prevalent helminth among the children,while Trichuris trichiura was found in only two subjects(0.8%).Previous infestations and the use of public toilets were found to be significantly associated with current infections(Ptation.

关键词： prevalence intestinal helminths school children

A Prefix Tree Based n-best List Re-scoring Strategy for Recurrent Neural Network Language Model

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Chinese Journal of Electronics 2014年第1期23卷 70-74页

作者： SI Yujing LI ta PAN Jielin YAN Yonghong The Key Laboratory of Speech Acoustics and Content Understanding Chinese Academy of Sciences

In this paper, issues of speeding up Recurrent neural network language model(RNNLM) in the testing phase are explored so that RNNLMs can be used to re-rank a large n-best list in real-time systems which could obtain better performance. A new n-best list rescoring framework, Prefix tree based n-best list re-scoring(PTNR), is proposed to hundred percent eliminate the repeated computations which makes n-best list re-scoring ineffective. At the same time, the bunch mode technique,widely-used in speeding up the training of Feed-forward neural network language model(FF-NNLM), is combined with PTNR and the speed is further improved. Experimental results show that our approach is much faster than basic n-best list re-scoring. take 1000-best as an example, our approach is almost 11 times faster than the basic n-best list re-scoring.

关键词： Recurrent neural network language model(RNNLM) n-best list Prefix tree based n-best list re-scoring(PTNR) Speedup Bunch mode

Crystallodiagnostics of some animals' helmintosis

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Asian Pacific Journal of Tropical Medicine 2010年第3期3卷 176-179页

作者： Andrew Martusevich Grishina aa.Bochkareva AV Laboratory of Physical and Chemical Medicine Institute of Traumatology and Orthopedics

Objective:To investigate the teziocrystalloscopic features of urine which were collected from both healthy rodents and those with ***:Physical-chemical characteristics of urine samples that were collected from 15 mice and 20 rats were estimated by their ability to *** test results were interpreted with integrated identity table which includes 5 main classes of the crystalline and amorphous *** quantitative and semiquantitative evaluation indicators were also ***:Presence of Trichinella spiralis in animal organism transformed results of the biofluid free *** main components of rats’ urine facia were single-crystalline rectangles which were made of cholesterol and its *** biofluid microsamples of healthy rats and rats with echinococcosis had both common and ***:Urine teziocrystalloscopic analysis is an informative method for diagnosis of helminthiasis in animals.

关键词： Biocrystallomics Trichinosis Echinococcosis Crystallodiagnostics Urine

Aspect-ratio dependent oscillatory thermocapillary convection in the floating half zone

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Science China(Physics,Mechanics & Astronomy) 2011年第2期54卷 338-341页

作者： aa.Yan LI Kai CAO ZhongHua HU WenRui Key Laboratory of Microgravity Institute of Mechanics Chinese Academy of Sciences Beijing 100190 China and National Microgravity Laboratory Institute of Mechanics Chinese Academy of Sciences Beijing 100190 China

The dependency of the critical Marangoni number on the geometrical aspect ratio of the floating half zone is essential to predict the onset of oscillatory thermocapillary *** experimental studies in the microgravity conditions on floating half zones of several centimeters in diameter have predicted that the critical Marangoni number increases with the increasing aspect ratio,and the terrestrial experimental studies have predicted the contradictory conclusion for floating half zones of several millimeters in *** the present work,terrestrial experimental studies were conducted on the floating half zones of 5 Centistokes(cSt) silicon oil and 10 cSt silicon *** experimental results show that the critical Marangoni number generally increases with the increasing aspect ratio of the floating half zone and then ***,a further increase of the critical Marangoni number with the increasing aspect ratio occurs for the slender floating half zones.

关键词： thermocapillary convection flow instability aspect ratio

Effect of artemether on hematological parameters of healthy and uninfected adult Wistar rats

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Asian Pacific Journal of Tropical Biomedicine 2012年第6期2卷 493-495页

作者： Osonuga IO Osonuga OA Osonuga A Onadeko aa.Osonuga aa Department of Physiology Olabisi Onabanjo University Department of Pharmacology Olabisi Onabanjo University School of Medical Sciences University of Cape Coast Department of Nursing University of Cape Coast

Objective:To evaluate the effect of short term artemether administration on some blood parameters in adult male Wistar ***:Sixty five albino rats with body weight of 190-220 g were used for the four-phased study. The animals were randomly divided into five groups. The first-four groups of 15 rats were further divided into 3 subgroups of 5 rats. The drug was administered orally at sub-optimal, therapeutic, and high doses of 25, 50 and 75 mg/kg bw,respectively to the rats for 1 day, 2 days and 3 days. Blood samples were collected by cardio-puncture from the rats for hematology at the end of each phase. The last group served as control,and they were given waterad ***:Artemether caused significant reduction(P<0.05)of the hematological profile of the animals in a dose dependent manner. Discontinuation of the drug use however showed gradual recovery of the depressed indices of the blood ***:The results suggest that artemether can induce reversible changes in hematological profiles of rats by extension man. This can probably aggravate anemia when artemether is administered to malaria patients. Hence, the study supports the use of the drug with cautione specially in patients prone to anemic tendencies.

关键词： Artemether Anemia Antimalaria Hematology Hematological profile Malaria Anemic tendency

Ethnomedicinal values of some selected plant species in Federal College of Wildlife Management

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Asian Pacific Journal of Tropical Medicine 2009年第4期2卷 19-26页

作者： Osunsina IOO Ogunjinmi aa.Ajani MO Department of Forestry and Wildlife Management University of AgriculturePMB 2240AbeokutaOgun StateNigeria Department of Forestry and Wildlife Management Faculty of AgricultureUniversity Of Port HarcourtPMB 5323Port HarcourtRivers StateNigeria Federal College of Wildlife Management PMB 268New BussaNiger StateNigeria

Objective:The objective of this study was to identify the ethno-medicinal values of some selected plant species in Federal College of Wildlife Management,New Bussa,Niger state,***:Three methods of data collection were employed:(1) reconnansance survey of the College Estate was carried out to identify some selected medicinal plants found within the area:(2) field observations alongside personal recognition of some of these plant species were carried out and(3) interview was also carried out in three villages around the College Estate to determine the plants being utilized by the *** villages were Kere,Labararu and Poppoi. The various uses of the identified plants and their parts used for the said purposes were *** hundred people were interviewed altogether in these *** information gathered on the medicinal uses of plants includes the type of plants,the part used to cure sickness,preparation of concoction,and the type of sickness *** data gathered were presented and analyzed using ***:The results revealed that the identified plant species were being used in curing various diseases such as dysentery,fever, stomach pains,cough,malaria,yellow fever,diarrhea,gonorrhea,pile,body pains and other ***: The study concluded that since the vast numbers of species in the study area possess medicinal values, there is need to conserve and protect the vegetation of the area from unsustainable exploitations which are the common features of vegetation in the surrounding land uses.

关键词： Ethnomedicinal values Plant species New Bussa Nigeria