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Journal of Modern Power Systems and Clean Energy 2023年第6期11卷 1756-1769页

作者： Yuan Chi anqi tao Xiaolong Xu Qianggang Wang Niancheng Zhou IEEE State Key Laboratory of Power Transmission Equipment and System Security and New Technology Chongqing UniversityChongqing 400044China

The deployment of dynamic reactive power sourcecan effectively improve the voltage performance after a disturbance for a power system with increasing wind power penetration level and ubiquitous induction *** improve the voltage stability of the power system,this paper proposes an adaptive many-objective robust optimization model to deal with thedeployment issue of dynamic reactive power ***,two metrics are adopted to assess the voltage stability of the system at two different stages,and one metric is proposed to assess the tie-line reactive power ***,a robustness index isdeveloped to assess the sensitivity of a solution when subjectedto operational uncertainties,using the estimation of acceptablesensitivity region(ASR)and D-vine *** objectives areoptimized simultaneously:①total equipment investment;②adaptive short-term voltage stability evaluation;③tie-line power flow evaluation;④prioritized steady-state voltage stabilityevaluation;and⑤robustness ***,an anglebased adaptive many-objective evolutionary algorithm(MaOEA)is developed with two improvements designed for the application in a practical engineering problem:①adaptive mutationrate;and②elimination procedure without a requirement for athreshold *** proposed model is verified on a modifiedNordic 74-bus system and a real-world power *** results demonstrate the effectiveness and efficiency of theproposed model.

关键词： Voltage stability reactive power planning robust many-objective optimization tie-line correlated uncertainty

Multi-stage Coordinated Robust Optimization for Soft Open Point Allocation in Active Distribution Networks with PV

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Journal of Modern Power Systems and Clean Energy 2023年第5期11卷 1553-1563页

作者： anqi tao Niancheng Zhou Yuan Chi Qianggang Wang Guangde Dong State Key Laboratory of Power Transmission Equipment and System Security and New Technology Chongqing UniversityChongqing 400044China State Grid Chongqing Electric Power Company Limited Chongqing 401123China

To optimize the placement of soft open points(SOPs)in active distribution networks(ADNs),many aspects should be considered,including the adjustment of transmission power,integration of distributed generations(DGs),coordination with conventional control methods,and maintenance of economic *** address this multi-objective planning problem,this study proposes a multi-stage coordinated robust optimization model for the SOP allocation in ADNs with photovoltaic(PV).First,two robust technical indices based on a robustness index are proposed to evaluate the operation conditions and robust optimality of the ***,the proposed coordinated allocation model aims to optimize the total cost,robust voltage offset index,robust utilization index,and voltage collapse proximity ***,the optimization methods of the multiand single-objective models are coordinated to solve the proposed multi-stage ***,the proposed model is implemented on an IEEE 33-node distribution system to verify its *** results show that the proposed index can better reveal voltage offset conditions as well as the SOP utilization,and the proposed model outperforms conventional ones in terms of robustness of placement plans and total cost.

关键词： Multi-stage coordinated optimization allocation robustness index soft open point(SOP) active distribution network

Aerial observations of sea ice and melt ponds near the North Pole during CHINARE2010

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Acta Oceanologica Sinica 2017年第1期36卷 64-72页

作者： LI Lanyu KE Changqing XIE Hongjie LEI Ruibo tao anqi Jiangsu Provincial Key Laboratory of Geographic Information Science and Technology Nanjing University Department of Geological Sciences University of Texas at San Antonio Polar Research Institute of China State Oceanic Administration

An aerial photography has been used to provide validation data on sea ice near the North Pole where most polar orbiting satellites cannot cover. This kind of data can also be used as a supplement for missing data and for reducing the uncertainty of data interpolation. The aerial photos are analyzed near the North Pole collected during the Chinese national arctic research expedition in the summer of 2010（CHINARE2010）. The result shows that the average fraction of open water increases from the ice camp at approximately 87°N to the North Pole, resulting in the decrease in the sea ice. The average sea ice concentration is only 62.0% for the two flights（16 and 19 August 2010）. The average albedo（0.42） estimated from the area ratios among snow-covered ice,melt pond and water is slightly lower than the 0.49 of HOTRAX 2005. The data on 19 August 2010 shows that the albedo decreases from the ice camp at approximately 87°N to the North Pole, primarily due to the decrease in the fraction of snow-covered ice and the increase in fractions of melt-pond and open-water. The ice concentration from the aerial photos and AMSR-E（The Advanced Microwave Scanning Radiometer-Earth Observing System） images at 87.0°–87.5°N exhibits similar spatial patterns, although the AMSR-E concentration is approximately 18.0%（on average） higher than aerial photos. This can be attributed to the 6.25 km resolution of AMSR-E, which cannot separate melt ponds/submerged ice from ice and cannot detect the small leads between floes. Thus, the aerial photos would play an important role in providing high-resolution independent estimates of the ice concentration and the fraction of melt pond cover to validate and/or supplement space-borne remote sensing products near the North Pole.

关键词： sea ice melt pond albedo concentration aerial observation North Pole

Comprehensive bioinformatics analysis and experimental validation:An anoikis-related gene prognostic model for targeted drug development in head and neck squamous cell carcinoma

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Oncology Research 2023年第5期31卷 715-752页

作者： LIN QIU anqi tao XIAOQIAN SUN FEI LIU XIANPENG GE CUIYING LI Central Laboratory Peking University School and Hospital of Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijing100081China Department of Dentistry Xuanwu Hospital Capital Medical UniversityBeijing100053China National Clinical Research Center for Geriatric Disorders Beijing100101China School of Medicine Nankai UniversityTianjin300071China Department of Oral and Maxillofacial Surgery Tianjin Stomatological HospitalSchool of MedicineNankai UniversityTianjin300041China

We analyzed RNA-sequencing(RNA-seq)and clinical data from head and neck squamous cell carcinoma(HNSCC)patients in The Cancer Genome Atlas(TCGA)Genomic Data Commons(GDC)portal to investigate the prognostic value of anoikis-related genes(ARGs)in HNSCC and develop new targeted *** expressed ARGs were screened using bioinformatics methods;subsequently,a prognostic model including three ARGs(CDKN2A,BIRC5,and PLAU)was *** results showed that the model-based risk score was a good prognostic indicator,and the potential of the three ARGs in HNSCC prognosis was validated by the TISCH database,the model’s accuracy was validated in two independent cohorts of the Gene Expression Omnibus *** correlation analysis and half-maximal inhibitory concentration were also performed to reveal the different landscapes of TIME between risk groups and to predict immuno-and chemo-therapeutic *** small-molecule drugs for HNSCC were subsequently predicted using the L1000FWD ***,in vitro experiments were used to verify the database *** relative ARG mRNA expression levels in HNSCC and surrounding normal tissues remained consistent with the model ***5 knockdown inhibited anoikis resistance in WSU-HN6 and CAL-27 *** docking,real-time PCR,cell counting kit-8(CCK-8),plate clone,and flow cytometry analyses showed that small-molecule drugs predicted by the database may target the ARGs in the prognostic model,inhibit HNSCC cells survival rate,and promote anoikis in ***,we constructed a new ARG model for HNSCC patients that can predict prognosis and immune activity and identify a potential small-molecule drug for HNSCC,paving the way for clinically targeting anoikis in HNSCC.

关键词： Head and neck squamous cell carcinoma Anoikis Prognosis Proliferation Apoptosis

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时间洞察力对跨期选择偏好的预测

心理科学 2015年第2期38卷 279-283页

作者：陶安琪刘金平冯廷勇西南大学心理学部重庆400715 河南大学教育科学学院开封475004

利用津巴多时间洞察力问卷,采用跨期选择经典范式,考察"现在享乐型"和"未来定向型"两类时间洞察力个体在跨期选择上的偏好,从人格特质角度来探究跨期选择的认知机制。结果发现:(1)现在享乐定向组的延迟折扣率显著高于未来定向组;(2)未... 详细信息

利用津巴多时间洞察力问卷,采用跨期选择经典范式,考察"现在享乐型"和"未来定向型"两类时间洞察力个体在跨期选择上的偏好,从人格特质角度来探究跨期选择的认知机制。结果发现:(1)现在享乐定向组的延迟折扣率显著高于未来定向组;(2)未来定向组在时间洞察力量表"未来维度"得分与延迟折扣率显著负相关。这说明时间洞察力对个体延迟折扣率具有预测作用,支持了跨期选择的时间感知基础模型。

关键词：跨期选择时间洞察力延迟折扣

The curative effect of zoledronic acid and pamidronic acid on treating ostealgia in malignant tumor with bone metastases and its side effects on serum calcium and phosphorus

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The Chinese-German Journal of Clinical Oncology 2011年第6期10卷 344-348页

作者： Yuedi Dai Meixing Wang Li tao anqi Li Haixia Wu Mi Xiao Department of Medical Oncology Minhang Branch of Cancer Hospital Fudan University Shanghai 200240 China

Objective： Bisphosphonates were widely used with the rate of malignant tumor with bone metastases increasing rapidly. The aim of this study was to evaluate zoledronic acid and pamidronic acid on treating ostealgia of malignant tumor with bone metastases and serum calcium, phosphorus and alkaline phosphorus movement. Methods： One Hundred cancer patients with bone metastases were diagnosed according to pathological and imaging methods. After zoledronic acid or pamidronic acid intravenous infusion one and two months, ostealgia degree, serum calcium, serum phosphorus and alkaline phosphorus were observed before bisphosphonates treatment, one and two months after treatment, respectively. Results： Ostealgia degree did not change significantly after diphosphonates treatment from one to two months （P 〉 0.05）. The linear correlation between serum calcium and serum phosphorus on bone metastases cancer patients before therapy was dismissed after bisphosphonates treatment one month and did not recover in two months. The incidence of hypo-calcium after diphosphonate treatment one month （54%） and two months （56%） were significantly increased than that before treatment （36%）（X2 = 6.55, P = 0.011; X2 = 8.05, P = 0.005）. Serum calcium and serum phosphorus were both decreased after treatment one month （t = 4.39, P = 0.000; t = 2.50, P = 0.014） and two months （t = 4.32, P = 0.000; t = 2.49, P = 0.010）. There had no difference between zoledronic acid and pamidronic acid on treating of ostealgia and serum calcium and phosphorus changing. Conclusion： Zoledronic acid and pamidronic acid can relief ostealgia of cancer patients with bone metastases and induce hypo-calcium, break the linear relationship between calcium and phosphorus. There have no difference between zoledronic acid and pamidronic acid on treating ostealgia and inducing hypo-calcium and hypo-phosphorus.

关键词： zoledronic acid pamidronic acid ostealgia calcium phosphorus

Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model

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Neural Regeneration Research 2025年第3期20卷 858-872页

作者： Xintian Ding Chun Chen Heng Zhao Bin Dai Lei Ye tao Song Shuai Huang Jia Wang tao You Department of Orthopedics The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Orthopedics Provincial Hospital Affiliated to Anhui Medical UniversityHefeiAnhui ProvinceChina

Reducing the secondary inflammatory response, which is partly mediated by microglia, is a key focus in the treatment of spinal cord injury. Src homology 2-containing protein tyrosine phosphatase 2(SHP2), encoded by PTPN11, is widely expressed in the human body and plays a role in inflammation through various mechanisms. Therefore, SHP2 is considered a potential target for the treatment of inflammation-related diseases. However, its role in secondary inflammation after spinal cord injury remains unclear. In this study, SHP2 was found to be abundantly expressed in microglia at the site of spinal cord injury. Inhibition of SHP2 expression using siRNA and SHP2 inhibitors attenuated the microglial inflammatory response in an in vitro lipopolysaccharide-induced model of inflammation. Notably, after treatment with SHP2 inhibitors, mice with spinal cord injury exhibited significantly improved hind limb locomotor function and reduced residual urine volume in the bladder. Subsequent in vitro experiments showed that, in microglia stimulated with lipopolysaccharide, inhibiting SHP2 expression promoted M2 polarization and inhibited M1 polarization. Finally, a co-culture experiment was conducted to assess the effect of microglia treated with SHP2 inhibitors on neuronal cells. The results demonstrated that inflammatory factors produced by microglia promoted neuronal apoptosis, while inhibiting SHP2 expression mitigated these effects. Collectively, our findings suggest that SHP2 enhances secondary inflammation and neuronal damage subsequent to spinal cord injury by modulating microglial phenotype. Therefore, inhibiting SHP2 alleviates the inflammatory response in mice with spinal cord injury and promotes functional recovery postinjury.

关键词： apoptosis glycolysis inflammatory response microglia neurons polarization spinal cord injury Src homology 2-containing protein tyrosine phosphatase 2

考虑网络增容与无功支撑的混合型智能软开关优化配置

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电力自动化设备 2024年第12期44卷 18-25页

作者：王健吴逸凡陶安琪王蕊王强钢周念成刘皓明易永利河海大学电气与动力工程学院江苏南京211100 国网重庆市电力公司电力科学研究院重庆401123 重庆大学输变电装备技术全国重点实验室重庆400044 国网浙江省电力有限公司温州供电公司浙江温州325000

传统智能软开关(SOP)替换联络开关的工作模式使得支路传输功率完全受到SOP容量约束,限制了含高比例分布式光伏配电网的潮流转移能力。为此设计了结构灵活、控制模式可变的混合型智能软开关(HOP),并提出了考虑网络增容与无功支撑协同的HO... 详细信息

传统智能软开关(SOP)替换联络开关的工作模式使得支路传输功率完全受到SOP容量约束,限制了含高比例分布式光伏配电网的潮流转移能力。为此设计了结构灵活、控制模式可变的混合型智能软开关(HOP),并提出了考虑网络增容与无功支撑协同的HOP优化配置方法。分析了HOP在不同支路传输容量下的4种控制模式,并建立了考虑联络线和SOP功率流向的HOP功率模型;为获得光伏出力和负荷需求代表性场景,提出了基于堆叠自编码器特征提取的场景生成方法;考虑到HOP联络开关状态对潮流和网络拓扑的影响,推导含HOP的支路潮流方程约束,建立了考虑配电网重构的HOP优化配置模型,并通过线性化处理将优化配置模型转化为混合整数线性规划问题。算例结果表明HOP能够应对支路增容需求,降低配电网规划成本,提升分布式光伏消纳能力。

关键词：混合型智能软开关配电网重构网络增容无功支撑场景生成优化配置

Preparation of FeCoNi medium entropy alloy from Fe^(3+)-Co^(2+)-Ni^(2+)solution system

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 92-101页

作者： Zongyou Cheng Qing Zhao Mengjie tao Jijun Du Xingxi Huang Chengjun Liu Key Laboratory for Ecological Metallurgy of Multimetallic Mineral(Ministry of Education) Northeastern UniversityShenyang 110819China School of Metallurgy Northeastern UniversityShenyang 110819China Engineering Research Center of Frontier Technologies for Low-carbon Steelmaking(Ministry of Education) Shenyang 110819China

In recent years,medium entropy alloys have become a research hotspot due to their excellent physical and chemical *** controlling reasonable elemental composition and processing parameters,the medium entropy alloys can exhibit similar properties to high entropy alloys and have lower *** this paper,a FeCoNi medium entropy alloy precursor was prepared via sol-gel and coprecipitation methods,respectively,and FeCoNi medium entropy alloys were prepared by carbothermal and hydrogen *** phases and magnetic properties of FeCoNi medium entropy alloy were *** showed that FeCoNi medium entropy alloy was produced by carbothermal and hydrogen reduction at 1500℃.Some carbon was detected in the FeCoNi medium entropy alloy prepared by carbothermal *** alloy prepared by hydrogen reduction was uniform and showed a relatively high ***,the hydrogen reduction product exhibited better saturation magnetization and lower coercivity.

关键词： medium entropy alloy sol-gel co-precipitation carbothermal hydrogen reduction

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未来时间洞察力与健康行为

科教导刊 2014年第10期 219-页

作者：陶安琪西南大学心理学部重庆400715

未来时间洞察力是个体对未来时间的认知、体验和行动(或行动倾向)的人格特质.它反映了人们对待未来时间的认识和态度,并最终推动个体行为指向未来的短期或长期目标.本文对时间洞察力的相关概念及其与健康行为的关系进行了概述.

关键词：时间洞察力未来时间洞察力健康行为