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Post-treatment with plant extracts used in Brazilian folk medicine caused a partial reversal of the antiproliferative effect of glyphosate in the Allium cepa test

引用

BIOCELL 2013年第2期37卷 23-28页

作者： VIVIANE DAL-SOUTO FRESCURA andrielle wouters kuhn HAYWOOD DAIL LAUGHINGHOUSE IV JUÇARA TEREZINHA PARANHOS SOLANGE BOSIO TEDESCO Department of Biology Centro de Ciências Naturais e Exatas(CCNE)Universidade Federal de Santa Maria(UFSM)Avenida Roraimanº1000Cep.97105-900CamobiSanta MariaRio Grande do SulBrasil Centre for Protein Engineering Institute of Chemistry B6University of LiègeBelgium.

Species of the genus Psychotria are used for multiple purposes in Brazilian folk medicine,either as water infusions,baths or *** study was aimed to evaluate the genotoxic and antiproliferative effects of infusions of Psychotria brachypoda and *** on the Allium cepa *** to distilled water was used as a negative control,while exposure to glyphosate was used as a positive *** interaction of extracts(as a post-treatment)with the effects of glyphosate was also *** showed that glyphosate and the extracts of both *** and *** reduced the mitotic index as compared with the negative control(distilled water).Surprisingly,however,both extracts from *** and *** caused a partial reversal of the antiproliferative effect of glyphosate when used as a *** also induced the highest number of cells with chromosomal alterations,which was followed by that of *** ***,the extracts from *** did not show any signifi cant genotoxic ***-treatment of glyphosate-treated samples with distilled water allowed a partial recovery of the genotoxic effect of glyphosate,and some of the Psychotria extracts also did ***,post-treatment of glyphosatetreated samples with *** extracts induced a statistically signifi cant apoptotic *** is concluded that *** extracts show antiproliferative effects and are not genotoxic,while extracts of *** show a less potent antiproliferative effect and may induce chromosomal *** fi nding of a partial reversion of the effects of glyphosate by a post-treatment with extracts from both plants should be followed up.

关键词： medicinal plants Psychotria brachypoda Psychotria birotula cell proliferation apoptosis

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