检索结果-南通市图书馆

Comparative Studies of Different Organs of Nyctanthes arbortristis in Modulation of Cytokines in Murine Model of Arthritis

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2007年第2期20卷 154-159页

作者： BRIJESH RATHORE BHOLANATH PAUL BHUSAN P CHAUDHURY ASHOK KUMAR SAXENA anand prakash sahu YOGENDRA KUMAR GUPTA Immunobiology Laboratory Central Pathology Laboratory Preventive Toxicology Laboratory Industrial Toxicology Research Centre M. G. MargLucknow 226001India

Objective To study the modulation effect of pro- and anti-inflammatory cytokines following long term use of water soluble ethanol extracts from different organs of Nyctanthes arbortristis （NAT） in mouse model of arthritis. Methods Arthritis was induced in mice by two injections of Freund＇s complete adjuvant on days 0 and 12 in the sub-planter surface of the right hind paw. Results Injection of adjuvant resulted in a maximum primary edema of the footpad with erythema, and edema and distortion of joints of the right hind paw after 24-48 hours. Second injection of FCA led to the formation of secondary swellings persisting more than four weeks that spread onto the other hind limb but to a lesser extent. Histological analysis of the ankle on day 47 showed marked evidence of cartilage destruction in association with pannus formation and moderate bone resorption. Proinfiammatory cytokine levels in the inflamed joint homogenate were elevated on days 2, 14, and 47. Oral administration of leaf and fruit extracts in arthritic mice reduced joint homogenate levels of tumor necrosis factor-α, interleukin-1β, and interleukin-6 on days 2, 14, and 47 in comparison to untreated arthritic mice. Intedeukin-10 level was elevated in the inflamed joint on days 2, 14, and 47 in comparisons to untreated arthritic mice. Confusion Evidence of lesser inflammation of the footpad and joint and associated histological observation support the therapeutic benefit of leaf and fruit extracts from Nyctanthes arbortristis. This study helps in understanding the mechanism of anti-inflammatory action of Nyctanthes arbortristis in the light of pro- and anti-inflammatory cytokine balance.

关键词： Nyctanthes arbortristis Arthritis TNF-α IL- 1β IL-6 IL-10

Efficient ID-based proxy multi-signature scheme secure in random oracle

在线全文

学校读者我要写书评

暂无评论

Frontiers of Computer Science 2012年第4期6卷 421-428页

作者： Rajeev anand sahu Sahadeo PADHYE Department of Mathematics Motilal Nehru National Institute of TechnologyAllahabad-211004India

Proxy signature schemes enable an entity to del- egate its signing rights to any other party, called proxy signer. As a variant of proxy signature primitive, proxy multi- signature allows a group of original signers to delegate their signing capabilities to a single proxy signer in such a way that the proxy signer can sign a message on behalf of the group of original signers. We propose a concrete ID-based proxy multi-signature scheme from bilinear pairings. The proposed scheme is existential unforgeable against adaptively chosen message and given ID-attack in random oracle model under the computational Diltie-Hellman （CDH） assumption. The fascinating property of new scheme is that the size of a proxy multi-signature is independent of the number of original sign- ers. Furthermore the proposed scheme is simple and com- putationally more efficient than other ID-based proxy multi- signature schemes.

关键词： ID-based signature scheme bilinear pairings,proxy multi-signature computational Diffie-Hellman prob-lem (CDHP) random oracle

Assessment of self-reacting bobbin tool friction stir welding for joining AZ31 magnesium alloy at inert gas environment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2019年第4期7卷 661-671页

作者： prakash Kumar sahu Nikhil P Vasudevan Bipul Das Sukhomay Pal Department of Mechanical Engineering and IDM Joint Lab Tsinghua UniversityBeijing 100084China Larsen and Toubro Limited HaziraSuratGujarat 394510India Department of Mechanical Engineering National Institute of Technology Silchar788010 AssamIndia Department of Mechanical Engineering Indian Institute of Technology Guwahati781039 AssamIndia

Research work presented in this study has the primary target of exploring joint attributes of AZ31 magnesium alloys using friction stir welding process with a modified tool referred as bobbin *** of inert and open atmosphere on mechanical properties are evaluated over a wide range of welding speed and tool rotation *** of the research findings from the inert atmosphere bobbin tool were made with the traditional process of friction stir *** results depicted improved joint properties for inert atmosphere *** and intermediate range of tool rotational speed is found to be favorable for bobbin tool friction stir welding without and with an inert medium,*** atmosphere due to inert medium leads to less oxidation of the AZ31 Mg alloy leading to superior joint *** investigations are also made with the aim of evaluating the impact of bobbin tool and inert medium on joint *** each aspect for joining of AZ31 Mg alloy,bobbin tool with inert medium is found to be an effective solution for joining with improved mechanical properties compared to without inert bobbin tool as well as conventional tool friction stir welding.

关键词： Mg FSW Bobbin tool Process parameters Mechanical properties Fractography Microstructural characterization

Multi-response optimization of process parameters in friction stir welded AM20 magnesium alloy by Taguchi grey relational analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2015年第1期3卷 36-46页

作者： prakash Kumar sahu Sukhomay Pal Department of Mechanical Engineering Indian Institute of Technology Guwahati781039 AssamIndia

The purpose of this paper is to optimize the process parameter to get the better mechanical properties of friction stir welded AM20 magnesium alloy using Taguchi Grey relational analysis(GRA).The considered process parameters are welding speed,tool rotation speed,shoulder diameter and plunging *** experiments were carried out by using Taguchi's L18 factorial design of *** processes parameters were optimized and ranked the parameters based on the *** percentage influence of each process parameter on the weld quality was also quantified.A validation experimental run was conducted using optimal process condition,which was obtained from the analysis,to show the improvement in mechanical properties of the *** study also shows the feasibility of the GRA with Taguchi technique for improvement in welding quality of magnesium alloy.

关键词： Friction stir welding Magnesium alloy Tensile strength Bending strength Micro-hardness Optimization Taguchi Grey relational analysis

Hybrid fuzzy-grey-Taguchi based multi weld quality optimization of Al/Cu dissimilar friction stir welded joints

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Manufacturing 2016年第3期4卷 237-247页

作者： prakash Kumar sahu Kanchan Kumari Sukhomay Pal Surjya K. Pal Department of Mechanical Engineering Indian Institute of Technology Guwahati Guwahati Assam 781039 India Department of Mechanical Engineering Indian Institute of Technology Kharagpur Kharagpur West Bengal 721302India

Nowadays aluminum alloys substitute copper in various applications for weight reduction and cost savings. This paper presents fuzzy-grey Taguchi technique for optimization of friction stir welding condition with seven weld quality attributes of dissimilar A1/Cu joints with the minimum number of experiments for effective productivity and product quality. Taguchi＇s L16 orthogonal array was used to conduct the experiments. Fuzzy inference system was adapted to convert the multi quality characteristics into an equivalent single quality parameter which was opti- mized by Taguchi approach. Four parameters namely, rotational speed of the tool, welding speed, plunging depth and tool pin offset were varied in four levels for investi- gating the effects on the process output like tensile strength, compressive strength, percentage of elongation, bending angle, weld bead thickness and average hardness at the nugget zone. The hardness profile is consistent with the variation of the structure within the nugget zone （NZ）. Confirmation experiment was conducted using predicted optimum parameter setting and it showed that the proposed approach could efficiently optimize weld quality parame- ters. The microstructural analyses were also performed for all the zones of the joints at both Al and Cu sides. It revealed the finer grain size at the NZ compared to the base material due to dynamic recrystallization.

关键词： Dissimilar friction stir welding - Grey relational analysis. Fuzzy inference system Multi-response optimization Mechanical properties Microstructural analysis

Sarcopenia in Chronic Liver Disease:A Metabolic Perspective

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Translational Hepatology 2022年第6期10卷 1213-1222页

作者： Ramesh Kumar Sabbu Surya prakash Rajeev Nayan Priyadarshi Utpal anand Department of Gastroenterology All India Institute of Medical SciencesPatnaIndia Department of Radiodiagnosis All India Institute of Medical SciencesPatnaIndia Department of Surgical Gastroenterology All India Institute of Medical SciencesPatnaIndia

Sarcopenia,a condition of low muscle mass,quality,and strength,is commonly found in patients with chronic liver disease(CLD)and is associated with adverse clinical out-comes including reduction in quality of life,increased mor-tality,and complications.A major contributor to sarcopenia in CLD is the imbalance in muscle protein turnover wherein changes in various metabolic factors such as hyperammone-mia,amino acid deprivation,hormonal imbalance,gut dys-biosis,insulin resistance,chronic inflammation,*** important *** particular,hyperammonemia is a key mediator of the liver-gut axis and is known to contribute to sarcopenia by various mechanisms including increased ex-pression of myostatin,increased phosphorylation of eukary-otic initiation factor 2a,cataplerosis ofα-ketoglutarate,mi-tochondrial dysfunction,increased reactive oxygen species that decrease protein synthesis and increased autophagy-mediated *** muscle is a major organ of insulin-induced glucose metabolism,and sarcopenia is closely linked to insulin resistance and metabolic *** with liver cirrhosis are in a hypermetabolic state that is associated with catabolism and depletion of amino acids,particularly branched-chain amino *** can have significant implications for nonalcoholic fatty liver disease,the most common form of CLD worldwide,because of the close link between metabolic syndrome and *** review discusses the potential metabolic derange-ment as a cause or effect of sarcopenia in CLD,as well as interorgan crosstalk,which that might help identifying a novel therapeutic strategies.

关键词： Sarcopenia Liver cirrhosis Chronic liver disease Metabolism Hy-perammonemia

Zooplankton Research in Indian Seas:A Review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Ocean University of China 2018年第5期17卷 1149-1158页

作者： SRICHANDAN Suchismita BALIARSINGH S.K. prakash Satya PANIGRAHY R.C. sahu K.C. Indian National Centre for Ocean Information Services Hyderabad 500090India Department of Marine Sciences Berhampur UniversityOdisha 760007India

To promote long-term studies on the distribution and diversity of marine zooplankton in Indian seas,a comprehensive review has been carried out based on the available *** studies in Indian waters started in the early 1900 s,and a plethora of literature has accumulated dealing with various aspects of zooplankton,especially from the Bay of Bengal,Arabian Sea and their associated estuaries and *** this review,a comprehensive description is offered on the species composition and distribution of zooplankton in the Indian *** is given to reflect the existing knowledge on the variations in zooplankton species composition in the Bay of Bengal and Arabian *** emerge as the most dominant component in all of these marine waters,as is the case *** are more diverse in the Bay of Bengal than in Arabian Sea.

关键词： zooplankton Arabian Sea Bay of Bengal coastal water oceanic water

Assessment of long-term climate variability and its impact on the decadal growth of horticultural crops in central India

在线全文

学校读者我要写书评

暂无评论

Ecological Processes 2022年第1期11卷 862-889页

作者： Gaurav Sharma Amita Sharma Nishant Kumar Sinha Om prakash Sharma Ashutosh Singh Ajai Kumar Pandey Abhishek Kumar Sudhir Kumar Trivedi Bharti Sao Mukesh Kumar sahu College of Horticulture and Forestry Rani Lakshmi Bai Central Agricultural UniversityJhansiUttar Pradesh 284003India Department of Environmental Science Rajmata Vijayaraje Scindia Krishi VishwavidyalayaGwaliorMadhya Pradesh 474002India Division of Soil Physics Indian Institute of Soil ScienceBhopalMadhya Pradesh 462038India Department of Floriculture and Landscape Architecture Indira Gandhi Krishi VishwavidyalayaRaipurChhattisgarh 492012India

Background:The impact of climate change on horticultural production is of utmost concern *** such vulnerable region of horticultural importance is the Madhya Pradesh state in the central part of *** is crucial to analyse the long-term trend in climatic variations and its effect on horticultural crop ***,this study focuses on detecting trends in mean annual precipitation and temperature of 115 years for the 15 districts covering all the regions of the state as well as projections of all the Representative Concentration Pathway(RCP)climatic scenarios for 2050 and 2080 of Madhya Pradesh *** decadal(2010–2020)insight into the area and production of horticultural crops is undertaken which will help forecasting the future growth *** a better insight,case study on four horticultural crops is undertaken to assess their decadal growth trend vis-à-vis climate parameters in these 15 ***:The Mann–Kendall test for 1901–2016 and Sen’s slope indicated a non-significant change in long-term trend for precipitation except for increasing change in Khargone and decreasing change in Rewa ***-cant increasing trend of average temperature is obtained for Hoshangabad,Jabalpur,Sagar and Rewa *** Sen’s slope indicated an increase of 0.005 to 0.009℃for maximum temperature and 0.005 to 0.012℃for minimum temperature *** projections of all the RCP climate scenarios for the years 2050 and 2080 indicated non-significant variation in precipitation but an increase in maximum(1.4 to 4.1℃)and minimum(1.45 to 4.65℃)annual *** increasing trend in area and production for horticultural crops is also observed in central India for the study *** is yield increase in all the crops selected in case study except for potato,which recorded a decreased yield between the years 2010–***:The Mann–Kendall test and projections indicate towards climate change with a temperature *** the decad

关键词： Climate change Horticulture Madhya Pradesh Precipitation Temperature Trend analysis

Broadcasting with Controlled Redundancy and Improved Localization in Wireless Sensor Networks

在线全文

学校读者我要写书评

暂无评论

Journal of Electronic Science and Technology 2013年第4期11卷 404-407页

作者： Tarun Dubey Om prakash sahu the Department of Electronics and Communication Engineering National Institute of Technology

Wireless sensor networks （WSNs） consist of sensor nodes that broadcast a message within a network. Efficient broadcasting is a key requirement in sensor networks and has been a focal point of research over the last few years. There are many challenging tasks in the network, including redundancy control and sensor node localization that mainly depend on broadcasting. In this paper, we propose a broadcasting algorithm to control redundancy and improve localization （BACRIL） in WSNs. The proposed algorithm incorporates the benefits of the gossip protocol for optimizing message broadcasting within the network. Simulation results show a controlled level of redundancy, which is up to 57.6% if the number of sensor nodes deployed in a 500 m×500 m area are increased from 50 to 500.

关键词： Broadcast gossip localization nodedensity redundancy wireless sensor networks.