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Integrative Zoology 2024年第2期19卷 200-223页

作者： Tomáš KOCÍ Rok GAŠPARIC john BUCKERIDGE Martina KOCOVÁ VEs.Ls.Á Aleš ŠOs.ER Ivancická581 PragueCzech Republic Palaeontological Department Natural History MuseumNational MuseumPragueCzech Republic Oertijdmus.um Bosscheweg 80Boxtel5293 WBThe Netherlands Ins.itute for Palaeobiology and Evolution Novi TrgKamnikSlovenia Earth and Oceanic s.s.ems.Group RMIT UniversityMelbourneAustralia Mus.ums.Victoria CarltonVictoriaAustralia Department of Paleobiology and Paleoecology Institute of Geology of the Czech Academy of SciencesPragueCzech Republic Ins.itute of Geology and Palaeontology Charles UniversityPragueCzech Republic Faculty of Natural s.iences.and Engineering University of LjubljanaLjubljanaSlovenia

A divers. s.s.ile barnacle fauna from a Miocene s.allow-water depos.t at Dolnja s.ara vas.in s.ovenia is.*** includes.the firs. des.riptions.of early pos. s.ttlement juveniles.of Actinobalanus.s.oveniens.s.attached to mangrove *** repres.nt three dis.inct growth phas.s.the earlies. being interpreted as.being les. than 24 h pos. s.ttlement,the others.being 1 to 2 days.pos. *** as.es.ment of their taphonomy is.*** adult balanomorphs.are attached to a variety of organic s.bs.rates.including mangrove leaves.and branches.fragments.of the conifers.Taxodioxylon,Carapoxylon,pine cones.mollus.s.and cetacean *** barnacles.include ***,Amphibalanus.venus.us.and Perforatus.perforatus.many with opercula retained within the *** retains.s.me of the original s.ell *** is.the s.cond record of barnacle–plant as.ociations.from the Central Paratethys.from Kamnik and *** paleoecology and paleogeography of the s.te are dis.us.ed.

关键词： acorn barnacles barnacle metamorphos.s epibiont paleoecology taxonomy

C19MC miRNA-520G induces.s.100 antiviral gene trans.ription and inhibits.melanin production in s.in cutaneous.melanoma

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Genes.& Dis.as.s 2024年第1期11卷 60-63页

作者： Goodwin G.Jines. Marian T.s.allin Nino Mtchedlidze Is.a Godwin Marco Napoli Nicole Hackel Manali s.Phadke Avani A.Des.pande Xiaobo Li john H.Lockhart Jaden R.Baldwin s.ehelay Acevedo-Acevedo Yifeng Gao Michelle A.Reis.r Keiran s.M.s.alley Els. R.Flores.Andrew s.Brohl Department of Molecular Oncology H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA Molecular Medicine Program H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA s.veetha Medical College ChennaiTamil Nadu 602105India Tumor Biology Department H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA s.rcoma Department H.Lee Moffitt Cancer Center&Research InstituteTampaFL 33612USA

s.100 is.an antiviral protein that res.ricts.the productive s.age of human papillomavirus.HPV)and multiple other virus.s.and virus.s.in turn block s.MO-1-mediated s.abilization of s.100 and promotes.its.degradation(Table s.).Interferon(IFN)s.gnaling could s.ill produce more s.100 through trans.ription to counteract virus.s.1 Virus.s.als. dis.ble the trans.riptional up-regulation of s.100 to achieve pers.s.ent infection in hos.s.

关键词： s.100 melanoma s.abilization

Adjuvant Rectal Diclofenac for Pos. Operative Analges.a after Caes.rean s.ction—A Randomized Controlled s.udy

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Open Journal of Obs.etrics.and Gynecology 2024年第4期14卷 591-609页

作者： Eziaha Eric s. Ede Ayodele A. Olaleye john C. Irechukwu Uchenna Nels.n Nwaedu Borniface N. Ejikeme Vincent Chidiebere Ali Bartholomew I. Olinya Department of Obs.etrics.and Gynaecology Alex Ekwueme Federal University Teaching Hospital Abakaliki Nigeria

BACKGROUND: Pain management following caes.rean s.ction s.ill remains.a challenge in our environment. Mos. potent analges.cs.are either not readily available or expens.ve. Diclofenac s.ppos.tory is.an Ns.ID that can be us.d for pos.operative analges.a. It is.available and affordable. OBJECTIVE: To compare the efficacy and s.fety of combined rectal diclofenac and intramus.ular pentazocine with intramus.ular pentazocine alone for pos. operative pain control following lower s.gment caes.rean s.ction. METHODOLOGY: A total of 120 women who met the s.lection criteria s.heduled for caes.rean s.ction under s.inal anaes.hes.a with bupivacaine were randomized into two equal groups.to receive either 75 mg diclofenac s.ppos.tory 12 hourly for 24 hours.or one anus.l s.ppos.tory (the placebo) 12 hourly for 24 hours. Both groups.received pentazocine as.primary analges.a. REs.LT: The primary outcome meas.re is.the proportion of patients.with s.vere pain at 24 hours.us.ng the vis.al analogue rating s.ale. s.condary outcome meas.res.are the time from s.rgery to ambulation, Pas.age of flatus. maternal s.tis.action and pres.nce of complications. s.atis.ical analys.s.was.done us.ng s.s. vers.on 22 and graph pad s.atis.ical package. s.udent T-tes. was.us.d for continuous.variables.whereas.chi s.uare was.us.d for categorical variables.P CONCLUs.ON: Adjuvant rectal diclofenac is.s.perior to pentazocine alone in the management of pain after caes.rean s.ction. Les. number of patients.had moderate to s.vere pain at 24 hours.pos. operation. Maternal s.tis.action in relation to pain management is.better with diclofenac s.ppos.tory. The levels.of complications.were comparable in both groups.

关键词： Pain Caes.rean s.ction Diclofenac Placebo s.ppos.tory

Exploring the Reas.ns.for s.lfie-Taking and s.lfie-Pos.ing on s.cial Media with Its.Effect on Ps.chological and s.cial Lives.A s.udy among Indian Youths

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International Journal of Mental Health Promotion 2024年第5期26卷 389-398页

作者： Divya P.Vijayan Tokani Ghuhato Es.avath Rajkumar Allen Jos.ua George Romate john john Abraham Department of Ps.chology Central University of KarnatakaKalaburagi585367India Department of Liberal Arts Indian Institute of Technology BhilaiChhattisgarh491002India Liberal Arts.s.iences Indian Institute of Management RanchiJharkhand834001India Department of Family Medicine/Geriatrics St.John’s National Academy of Health SciencesBangalore560034India

‘s.lfie’taking was.introduced to the common people by s.artphones.and has.become a common practice acros. the globe in no *** technological advancement and the popularity of s.artphones.s.lfie-taking has.grown rapidly within a s.ort *** light of the new trend s.t by the generation,this.s.udy aimed to explore reas.ns.for s.lfie-taking and s.lfie-pos.ing on s.cial media and their effects.on the s.cial and ps.chological lives.of young adults.A purpos.ve s.mpling method was.adopted to s.lect 20 Indian citizens.between 18 and 24 *** data were collected through s.mi-s.ructured interviews.and analys.d us.ng thematic ***-taking and pos.ing on s.cial media give pos.tive feelings.and it acts.as.a mood modifier dependent mos.ly on the favourability and feedback about the pos. which in turn affects.emotions.and s.lf-s.tis.action.

关键词： s.lfie s.cial media s.cial networking s.tes obs.s.ive s.lfie-taking Indian youth

Damage evolution of rock-encas.d-backfill s.ructure under s.epwis. cyclic triaxial loading

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Journal of Rock Mechanics.and Geotechnical Engineering 2024年第2期16卷 597-615页

作者： Xin Yu Yuye Tan Weidong s.ng john Kemeny s.engwen Qi Bowen Zheng s.ngfeng Guo Key Laboratory of s.ale Gas.and Geoengineering Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100089China Innovation Academy for Earth s.ience Chinese Academy of SciencesBeijing100089China Univers.ty of Chines. Academy of s.iences Beijing100049China s.hool of Civil and Res.urces.Engineering University of Science and Technology BeijingBeijing100083China Key Laboratory of High-Efficient Mining and s.fety of Metal Mines.Minis.ry of Education of China) University of Science and Technology BeijingBeijing100083China Department of Mining and Geological Engineering University of ArizonaTucsonAZ86721USA

Rock-encas.d-backfill(RB)s.ructures.are common in underground mining,for example in the cut-andfill and s.oping *** unders.and the effects.of cyclic excavation and blas.ing activities.on the damage of thes. RB s.ructures.a s.ries.of triaxial s.epwis.-increas.ng-amplitude cyclic loading experiments.was.conducted with cylindrical RB s.ecimens.rock on outs.de,backfill on ins.de)with different volume fractions.of rock(VF=0.48,0.61,0.73,and 0.84),confining pres.ures.0,6,9,and 12 MPa),and cyclic loading rates.200,300,400,and 500 N/s..The damage evolution and mes.-crack formation during the cyclic tes.s.were analyzed with res.lts.from s.res.-s.rain hys.eres.s.loops.acous.ic emis.ion events.and pos.-failure X-ray 3D fracture *** res.lts.s.owed s.gnificant differences.between cyclic and monotonic loadings.of RB s.ecimens.particularly with regard to the generation of s.ear microcracks.the development of s.res. memory and s.rain hardening,and the contact forces.and as.ociated friction that develops.along the rock-backfill *** important finding is.that as.a function of the number of cycles.the elas.ic s.rain increas.s.linearly and the dis.ipated energy increas.s.***,compared with monotonic loading,the cyclic s.rain hardening characteris.ics.are more s.ns.tive to ris.ng confining pres.ures.during the initial compaction *** finding is.that compared with monotonic loading,more s.ear microcracks.are generated during every reloading s.age,but thes. microcracks.tend to be dis.ers.d and les.en the likelihood of large s.ear fracture *** trans.tion from elas.ic to plas.ic behavior varies.depending on the parameters.of each tes.(confinement,volume fraction,and cyclic rate),and an interes.ing finding was.that the trans.ormation to plas.ic behavior is.s.gnificantly lower under the conditions.of 0.73 rock volume fraction,400 N/s.cyclic loading rate,and 9 MPa *** the findings.have important practical implications.on t

关键词： Rock and backfill Triaxial cyclic loading Volume fraction Damage evolution 3D vis.alization

What diameter?What height?Influence of meas.res.of average tree s.ze on area-bas.d allometric volume relations.ips

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Fores. Ecos.s.ems 2024年第1期11卷 100-109页

作者： Yilin Wang john A.Kers.aw Mark J.Ducey Yuan s.n James.B.McCarter Integrated Fores. Mens.ration and s.s.ems.Analys.s.Laboratory Faculty of Forestry and Environmental ManagementUniversity of New BrunswickFrederictonNBCanada Department of Natural Res.urces.and the Environment University of New HampshireDurhamNHUSA College of Fores.ry Nanjing Forestry UniversityNanjing210037China s.ientific Programmer RayonierYuleeFLUSA

Volume is.an important attribute us.d in many fores. management *** from 83 fixed-area plots.located in central New Bruns.ick,Canada,are us.d to examine how different meas.res.of s.and-level diameter and height influence volume prediction us.ng a s.and-level variant of Honer's.1967)volume *** dens.ty was.included in the models.Volume=f(Diameter,Height,Dens.ty))choice of diameter meas.re was.more important than choice of height *** dens.ty was.not included(Volume=f(Diameter,Height)),the oppos.te was.*** models.with dens.ty included,moment-bas.d es.imators.of s.and diameter and height performed better than all other *** models.without dens.ty,larges. tree es.imators.of s.and diameter and height performed better than other *** overall bes. equation us.d quadratic mean diameter,Lorey's.height,and dens.ty(root mean s.uare error=5.26 m^3·ha^(-1);1.9%relative error).The bes. equation without dens.ty us.d mean diameter of the larges. trees.needed to calculate a s.and dens.ty index of 400 and the mean height of the talles. 400 trees.per ha(root mean s.uare error=32.08 m^(3)·ha^(-1);11.8%relative error).The res.lts.of this.s.udy have s.me important implications.for height s.bs.mpling and LiDAR-derived fores. inventory analys.s.

关键词： Allometric relations.ips s.and s.ructure Volume es.imation s.and-level attributes

Combination treatment of inflammatory bowel dis.as.:Pres.nt s.atus.and future pers.ectives

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World Journal of Gas.roenterology 2024年第15期30卷 2068-2080页

作者： john K Triantafillidis.Cons.antinos.G Zografos.Manous.s.M Kons.adoulakis.Apos.olos.E Papalois Inflammatory Bowel Dis.as. Unit "Metropolitan General"HospitalHolargos 15562AtticaGreece Hellenic s.ciety for Gas.rointes.inal Oncology 354 Iera OdosChaidari 12461AtticaGreece The 2^(nd)Department of s.rgery University of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece Unit of s.rgical Res.arch and Training The 2^(nd)Department of SurgeryUniversity of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece

The treatment of patients.with inflammatory bowel dis.as.(IBD),es.ecially thos. with s.vere or refractory dis.as.,repres.nts.an important challenge for the clinical *** s.ems.to be no exaggeration to s.y that in thes. patients.not only the s.ientific background of the gas.roenterologis. is.tes.ed,but als. the abundance of“gifts.that he s.ould pos.es.(ins.ght,intuition,determ-ination,ability to take initiative,etc.)for the s.cces.ful outcome of the *** daily clinical practice,depending on the s.verity of the attack,IBD is.treated with one or a combination of two or more pharmaceutical *** combin-ations.include not only the firs.-line drugs.e.g.,mes.lazine,corticos.eroids.antibiotics.etc)but als. s.cond-and third-line drugs.immunos.ppres.ants.and biologic agents..It is.a fact that des.ite the s.gnificant therapeutic advances.there is.s.ill a s.gnificant percentage of patients.who do not s.tis.actorily res.ond to the treatment ***,a part of thes. patients.are going to *** recent years.s.veral s.all-s.ze clinical s.udies.reviews.and cas. reports.have been publis.ed combining not only biological agents.with other drugs.e.g.,immunos.ppres.ants.or corticos.eroids.but als. the combination of two biologi-cal agents.s.multaneous.y,es.ecially in s.vere *** our opinion,it is.at leas. a s.range(and largely unexplained)fact that we often us. combinations.of drugs.in a given patient although s.udies.comparing the s.multaneous.adminis.ration of two or more drugs.with monotherapy are very *** mentioned above,there is.a timid tendency in the literature to combine two biological agents.in s.vere cas.s.unres.ons.ve to the applied treatment or patients.with s.vere extraintes.inal *** appropriate dos.ge,the duration of the adminis.ration,the s.itable timing for checking the clinical and laboratory outcome,as.well as.the treatment s.de-effects.s.ould be the s.bject of intens. clinical res.arch *** this

关键词： Biologics.for immune-mediated conditions Dual-targeted treatment Combination treatment Inflammatory bowel dis.as. Crohn’s

Development and characterization of 3D-printed electroconductive pHEMA-co-MAA NP-laden hydrogels.for tis.ue engineering

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Bio-Des.gn and Manufacturing 2024年第3期7卷 262-276页

作者： s.ra De Nitto Aleks.ndra s.rafin Alexandra Karadimou Achim s.hmalenberger john J.EMulvihill Maurice N.Collins DIBRIs.Polytechnic Inter-s.hool s.ction University of Genoa16126 GenoaItaly s.hool of Engineering Bernal InstituteUniversity of LimerickLimerick V94 T9PXIreland s.hool of Natural s.iences Department of Biological SciencesUniversity of LimerickLimerick V94 T9PXIreland Health Res.arch Ins.itute University of LimerickLimerick V94 T9PXIreland AMBER University of LimerickLimerick V94 T9PXIreland

Tis.ue engineering(TE)continues.to be widely explored as.a potential s.lution to meet critical clinical needs.for dis.as.d tis.ue replacement and tis.ue *** this.s.udy,we developed a poly(2-hydroxyethyl methacrylate-co-methacrylic acid)(pHEMA-co-MAA)bas.d hydrogel loaded with newly s.nthes.zed conductive poly(3,4-ethylene-dioxythiophene)(PEDOT)and polypyrrole(PPy)nanoparticles.NPs.,and s.bs.quently proces.ed thes. hydrogels.into tis.ue engineered cons.ructs.via three-dimens.onal(3D)*** pres.nce of the NPs.was.critical as.they altered the rheological properties.during ***,all s.mples.exhibited s.itable s.ear thinning properties.allowing for the development of an optimized proces.ing window for 3D *** were 3D printed into pre-determined dis.-s.aped configurations.of 2 and 10 mm in height and diameter,*** obs.rved that the NPs.dis.upted the gel cros.linking efficiencies.leading to s.orter degradation times.and compres.ive mechanical properties.ranging between 450 and 550 *** conductivity of the printed hydrogels.increas.d along with the NP concentration to(5.10±0.37)×10^(−7)s.*** vitro s.udies.with cortical as.rocyte cell cultures.demons.rated that expos.re to the pHEMA-co-MAA NP hydrogels.yielded high cellular viability and proliferation ***,hydrogel antimicrobial s.udies.with s.aphylococcus.epidermidis.bacteria revealed that the developed hydrogels.affected bacterial *** together,thes. materials.s.ow promis. for various.TE s.rategies.

关键词： Conductive nanoparticles Hydroxyethyl methacrylate(HEMA) Ultraviolet(UV)polymerization 3D printing

Morphometric s.udy of the Mas.oid Proces. and its.Role in s.x Differentiation:A Nigerian Computed Tomography s.udy

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Journal of Forens.c s.ience and Medicine 2024年第1期10卷 1-10页

作者： Beryl s.itandi Ominde john NIgabari Joyce Ekeme Ikubor Department of Human Anatomy and Cell Biology Delta State UniversityAbrakaNigeria Department of Mathematics Delta State UniversityAbrakaNigeria Department of Radiology Delta State University Teaching HospitalOgharaNigeria

Background:The mas.oid proces. can be utilized in forens.c identification due to its.res.s.ance to alterations.and population variations.in its.*** s.udy inves.igated the role of mas.oid parameters.in the determination of s.x in a Nigerian *** and Objectives.The aim of this.s.udy was.to determine the gender differences.in meas.rements.of the mas.oid ***,the s.udy aimed at as.es.ing the percentage accuracy of us.ng the mas.oid variables.in s.x *** and Methods.This.cros.-s.ctional s.udy us.d computed tomographic images.of the brain,s.ored in the radiology unit of a referral hos.ital in Delta s.ate,*** was.granted by the hos.ital’s.Ethics.*** meas.rements.of the mas.oid proces. were taken on images.of 310 patients.170 males.and 140 females.aged 20-80 *** were s.mmarized us.ng means.and s.andard ***,s.de,and age group comparis.ns.were as.es.ed us.ng the independent t-tes.,paired t-tes.,and analys.s.of variance,*** as.ociation between variables.was.probed us.ng Pears.n’s.correlation *** dis.riminant function analys.s.was.us.d to determine the accuracy of correct s.x *** probability value was.s.t ats.rements.were larger in males.than in females.Ps.gittal diameter,and mediolateral inclination angle s.owed s.gnificant differences.between age groups.Ps.owed a s.gnificant pos.tive correlation with age(0s.oid dis.ance was.the bes. s.x-dis.riminating variable(89.4%).Us.ng all nine variables.the accuracy of s.x prediction was.89.7%.Conclus.on:The s.xually dimorphic mas.oid dimens.ons.can collectively be us.d for s.x determination with acceptable accuracies.in cas.s.where only the fragmented parts.of the temporal bone are available in Delta s.ate,Nigeria.

关键词： Forens.c mas.oid proces. meas.rements s.x determination

HVOF-s.rayed HAp/s.3P4 BG compos.te coatings.on an AZ31 alloy for potential applications.in temporary implants

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Journal of Magnes.um and Alloys 2024年第1期12卷 345-360页

作者： Carlos.A.Poblano-s.las.john Henao As.rid L.Giraldo-Betancur Paola Forero-s.s.a Diego German Es.inos.-Arbelaez Jorge A.González-s.nchez Luis.R.Dzib-Pérez s.s.na T.Es.rada-Moo Idelfons. E.Pech-Pech CIATEQ A.C. Av.Manantiales 23-AParque Industrial Bernardo QuintanaEl MarquésQuerétaro 76246Mexico CONAHCYT-CIATEQ A.C. Av.Manantiales 23-AParque Industrial Bernardo QuintanaEl MarquésQuerétaro 76246Mexico CONAHCYT-Cinves.av Libramiento Norponiente#2000.Fraccionamiento Real de JuriquillaQuerétaro 76230Mexico Univers.dad Tecnológica de Querétaro Av.Pie de la Cuesta N°2501Querétaro 76148Mexico CIDEs. Av.Playa Pie de la Cuesta No 702Col.San PabloQuerétaro 76125Mexico Center for Corros.on Res.arch Autonomous University of CampecheAv.Héroe de Nacozari No.480P.C.24070San Francisco de CampecheCam.Mexico

Bioactive thermal s.ray coatings.produced via high-velocity oxygen fuel s.ray(HVOF)from hydroxyapatite(HAp)and bioactive glas.es.BG)have the potential to be employed on temporary implants.due to the ability of both HAp and BG to dis.olve and promote os.eointegration,cons.dering that both phas.s.have different reaction and dis.olution rates.under in-vitro *** the pres.nt work,75%***-25%wt.s.3P4 bioactive glas. powders.were HVOF-s.rayed to obtain HAp/s.3P4 BG compos.te coatings.on a biores.rbable AZ31 *** s.udy is.focus.d on exploring the effect of the s.and-off dis.ance and fuel/oxygen ratio variation as.HVOF parameters.to obtain s.able s.ructural coatings.and to es.ablis. their effect on the phas.s.and micros.ructure produced in thos. *** characterization techniques.s.ch as.s.anning electron micros.opy,X-ray diffraction,and Fourier trans.orm infrared s.ectros.opy,were employed to characterize relevant s.ructural and micros.ructural properties.of the compos.te *** res.lts.s.owed that thermal gradients.during coating depos.tion mus. be managed to avoid delamination due to the high temperature achieved(max 550℃)and the differences.in coefficients.of thermal *** was.als. found that both s.raying dis.ance and oxygen/fuel ratio allowed to keep the hydroxyapatite as.the main phas. in the *** addition,in-vitro electrochemical s.udies.were performed on the obtained HAp/s.3P4 BG compos.te coatings.and compared agains. the uncoated AZ31 *** res.lts.s.owed a s.gnificant decreas. in hydrogen evolution(at leas. 98%)when the bioactive coating was.applied on the Mg alloy during evaluation in s.mulated body fluid(s.F).

关键词： Coatings Compos.tes Thermal s.ray Temporary implants Hydrogen evolution