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Formation potential and analysis of 32 regulated and unregulated disinfection by-products: Two new simplified methods

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Journal of Environmental Sciences 2022年第7期34卷 209-221页

作者： Jillian N.Murakami Xu Zhang Joanne Ye amy M.MacDonald Jorge Perez David W.Kinniburgh Susana Y.Kimura Department of Chemistry University of CalgaryCalgaryAlbertaT2N 1N4Canada Alberta Centre for Toxicology University of CalgaryCalgaryAlbertaT2N 4N1Canada

Water disinfection is an essential process that provides safe water by inactivating pathogens that cause waterborne diseases. However, disinfectants react with organic matter naturally present in water, leading to the formation of disinfection by-products(DBPs). Multi-analyte methods based on mass spectrometry(MS) are preferred to quantify multiple DBP classes at once however, most require extensive sample pre-treatment and significant resources. In this study, two analytical methods were developed for the quantification of 32 regulated and unregulated DBPs. A purge and trap(P&T) coupled with gas chromatography mass spectrometry(GC-MS) method was optimized that automated sample pre-treatment and analyzed volatile and semi-volatile compounds, including trihalomethanes(THMs), iodinated trihalomethanes(I-THMs), haloacetonitriles(HANs), haloketones(HKTs) and halonitromethanes(HNMs). lOQs were between 0.02-0.4 μg/l for most DBPs except for 8 analytes that were in the low μg/l range. A second method with liquid chromatography(lC) tandem mass spectrometry(MS/MS) was developed for the quantification of 10 haloacetic acids(HAAs) with a simple clean-up and direct injection. The lC-MS/MS direct injection method has the lowest detection limits reported(0.2-0.5 μg/l). Both methods have a simple sample pre-treatment, which make it possible for routine analysis. Hyperchlorination and uniform formation conditions(UFC) formation potential tests with chlorine were evaluated with water samples containing high and low TOC. Hyperchlorination formation potential test maximized THMs and HAAs while UFC maximized HANs. Ascorbic acid was found to be an appropriate quencher for both analytical methods. Disinfected drinking water from four water utilities in Alberta, Canada were also evaluated.

关键词： Disinfection byproducts Purge and trap lC-MS/MS Drinking water DBP formation potential HAAs HANs

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Pathology and genetic connectedness of the mangrove crab (Aratus pisonii) – a foundation for understanding mangrove disease ecology

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Animal Diseases 2022年第2期2卷 73-88页

作者： Jamie Bojko amy l.Burgess Thomas W.Allain Erica P.Ross Devon Pharo Jan F.Kreuze Donald C.Behringer National Horizons Centre Teesside UniversityDarlington DL11HGUK School of Health and life Sciences Teesside UniversityMiddlesbrough TS13BXUK Fisheries and Aquatic Sciences University of FloridaGainesvilleFL 32653USA Emerging Pathogens Institute University of FloridaGainesvilleFL 32611USA Florida Fish and Wildlife Research Institute MarathonFL 33050USA International Potato Centre(CIP) Apartado 1558LimaPeru

Mangrove forests are productive ecosystems,acting as a sink for CO_(2),a habitat for a diverse array of terrestrial and marine species,and as a natural barrier to coastline *** species that reside within mangrove ecosystems have important roles to play,including litter decomposition and the recycling of *** are important detritivores in such ecosystems and understanding their limitations(***)is an important endeavour when considering the larger ecological services *** and metagenomics were used to identify viral(Nudiviridae,Alphaflexiviridae),bacterial(Paracoccus sp.,'Candidatus Gracilibacteria sp.’,and Pseudoalteromonas sp.),protozoan,fungal,and metazoan diversity that compose the symbiome of the mangrove crab,Aratus *** symbiotic groups were observed at varying prevalence under histology:nudivirus(6.5%),putative gut epithelial virus(3.2%),ciliated protozoa(35.5%),gonad fungus(3.2%),gill ectoparasitic metazoan(6.5%).Metagenomic analysis of one specimen exhibiting a nudivirus infection provided the complete host mitochondrial genome(15,642 bp),nudivirus genome(108,981 bp),and the genome of a Cassava common mosaic virus isolate(6387 bp).Our phylogenetic analyses group the novel nudivirus with the Gammanudivirus and protein similarity searches indicate that Carcinus maenas nudivrius is the most similar to the new *** mitochondrial genome were used to mine short fragments used in population genetic studies to gauge an idea of diversity in this host species across the USA,Caribbean,and central and southern *** study report several new symbionts based on their pathology,taxonomy,and genomics(where available)and discuss what effect they may have on the crab *** role of mangrove crabs from a OneHealth perspective were explored,since their pathobiome includes cassava-infecting ***,given that this species is abundant in mangrove forests and now boasts a well-described pathogen prof

关键词： Alphaflexiviridae Nudiviridae Mitochondria Pathology Histology Metagenomics

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Moving from Efficacy to Effectiveness:Red Palm Oil's Role in Preventing Vitamin A Deficiency

Moving from Efficacy to Effectiveness:Red Palm Oil's Role in...

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作者： amy l.Rice Jennifer B.Burns Social Sectors Development Strategies Inc.BostonMassachusetts Johns Hopkins University BaltimoreMaryland

Vitamin A deficiency is one of the most widespread nutritional deficiencies *** of millions of children and tens of millions of women living in Sub-Saharan Africa and Southeast Asia are at particularly high risk of the adverse health consequences associated with this largely preventable *** palm oil comes from oil palms that are traditionally grown in tropical regions of West Africa and are now cultivated on a large-scale commercial basis in Southeast *** palm oil is the richest naturally occurring source of beta-carotene,a carotenoid that the human body can convert into usable vitamin A(retinol).This paper reviews a series of key intervention studies designed to investigate the impact of using red palm oil-based

关键词： red palm oil beta-carotene retinol vitamin A deficiency humans

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第52例——关于脓毒症及脓毒性休克治疗的几个观点(Internet网上专题讨论)

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中国危重病急救医学 2003年第1期15卷 62-64页

作者：冯丽洁 amy l.Szyszko 解放军总医院急诊科北京100853 美国芝加哥Illinosis医学院急诊科

2002年10月，欧洲危重病协会（ESICM）、危重病协会（SCCM）和国际脓毒症论坛提出了《巴塞罗那宣言》，共同呼呈采取措施减少世界最古老、最具杀伤力的疾病-脓毒症，争取在今后5 a内将脓毒症的死亡率降低25%。ESICM主席Graham Ramsay教... 详细信息

2002年10月，欧洲危重病协会（ESICM）、危重病协会（SCCM）和国际脓毒症论坛提出了《巴塞罗那宣言》，共同呼呈采取措施减少世界最古老、最具杀伤力的疾病-脓毒症，争取在今后5 a内将脓毒症的死亡率降低25%。ESICM主席Graham Ramsay教授指出，临床医生一直在寻求最好的脓毒下治疗方法，但是各国政府没有以足够的资金和教育来支持，医生的努力受到限制，《巴塞罗那宣言》将促进政府和医学管理部门提高对脓毒症社会危害的认识和干预。对于医学界和学术界而言，《巴塞罗那宣言》的意义在于：制定简单明了的定义，以促进早期、正确诊断；规范临床治疗和干预方案，确保适当、及时处理患者；制定全球统一的医疗指南；为临床医生提供脓毒症治疗的最先进学术信息；为ICU的脓毒症患者提供教育和咨询。

关键词：脓毒症脓毒性休克治疗 Internet 专题讨论

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Ethical challenges in vascularized composite allotransplantation of the lower extremity:lessons learned from hand transplantation and implications for the future

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Plastic and Aesthetic Research 2022年第1期9卷 196-212页

作者： amy l.Xu Casey Jo Humbyrd Department of Orthopaedic Surgery Johns Hopkins HospitalBaltimoreMD 21287USA Department of Orthopaedic Surgery Hospital of the University of PennsylvaniaPhiladelphiaPA 19106USA

Vascularized composite allotransplantation(VCA)is a novel surgical practice that involves the transplantation of multiple tissue types as a functional unit without the primary purpose of extending *** VCA of the upper extremity is becoming increasingly accepted and performed,VCA of the lower extremity remains largely unexplored despite its acknowledged potential *** are inherent ethical concerns surrounding VCA that are dominated by a conflict between the principles of beneficence and *** primary question is whether the quality-of-life benefits to the patient outweigh the risks associated with long-term immunosuppression for a non-lifesaving *** addition,the ethical conversation involves concerns regarding informed consent,donor autonomy,patient privacy and public disclosure,patient selection,and unique considerations in the pediatric *** extremity VCA has additional ethical issues compared to upper extremity VCA,as current lower limb prostheses provide excellent,near baseline function that upper limb constructs have not yet been able to *** this review,we discuss the ethical challenges of lower extremity VCA using available evidence for the upper *** also compare ethical considerations of VCA of the extremity with other surgical alternatives to limb loss-namely,limb salvage and replantation-and address how the conversation may be altered with further advancements in immunosuppression and prosthetic technology.

关键词： Vascularized composite allotransplantation(VCA) lower extremity ethics limb salvage replantation

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Uranium Series Disequilibrium and Precision Measurement of Radionuclides Activity in Sediment Sample Using low Background Gamma Spectrometry

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Journal of Geoscience and Environment Protection 2023年第10期11卷 119-140页

作者： Abdul J. Khan Umme-Farzana Syed amy l. Roselan Cynthia A. Costello laboratory of Inorganic and Nuclear Chemistry Division of Environmental Health Sciences Wadsworth Center New York State Department of Health Empire State Plaza Albany NY USA Bureau of Environmental Radiation Protection New York State Department of Health Empire State Plaza Albany NY USA

low background gamma spectrometry was used to measure the radionuclides activity of 238U, 232Th, and 235U series as well as 40K and 137Cs in a sediment sample. The goal of the study was to measure the 238U (63.3 keV peak of 234Th;1001 keV peak of 234mPa) and 235U (143.76 keV, 163.33 keV, and 205.31 keV peaks) activity by low background gamma spectrometry in sediment sample. 235U activity in environmental samples is difficult to accurately measure by gamma spectrometry due to its low abundance in nature and low gamma line intensities at 143.76 keV, 163.33 keV, and 205.31 keV. We have shown that by using low background gamma spectrometry, it is possible to accurately measure the 235U activity in sediment samples. The 235U activity was measured without using the major peak of 185.7 keV (Iγ = 57.2%) which requires interference correction from 186.21 keV of 226Ra. 226Ra activity was determined by measuring 222Rn daughters (214Pb and 214Bi). The precision and accuracy of the gamma activity measurement in the sediment sample were verified by using the HPGe detectors with Certified Reference Material (CRM) Irish Sea Sediment (IAEA-385). The results obtained for the 63.33 keV energy line of 234Th are compared with the 1001 keV energy line of 234mPa. The values of 238U and 235U activities, as well as 40K, 137Cs, and 226Ra, agreed with the certificate values of CRM. The results show that the 238U is in equilibrium with its daughters (234Th, 234mPa, and 210Pb). 232Th is also in equilibrium with its daughters (228Ra, 212Pb, 212Bi and 208Tl). 235U/238U activity ratio of 0.046 ± 0.007 in the

关键词： low Background Gamma Spectrometry HPGe Detector Sediment 238U 235U Secular Equilibrium

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Genetic architecture of quantitative trait loci(QTl)for FHB resistance and agronomic traits in a hard winter wheat population

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The Crop Journal 2023年第6期11卷 1836-1845页

作者： Yuzhou Xu Yaoguang li Ruolin Bian Guorong Zhang Allan K.Fritz Yanhong Dong lanfei Zhao Yunfeng Xu Nida Ghori amy Bernardo Paul StAmand Jessica l.Shoup Rupp Myron Bruce Wei Wang Eduard Akhunov Brett Carver Guihua Bai Department of Agronomy Kansas State UniversityManhattanKS 66506USA Department of Plant Pathology University of MinnesotaSt.PaulMN 55108USA Hard Winter Wheat Genetics Research Unit USDAManhattanKS 66506USA Department of Plant Pathology Kansas State UniversityManhattanKS 66506USA Department of Plant and Soil Sciences Oklahoma State UniversityStillwaterOK 74078USA

Wheat resistance to Fusarium head blight(FHB)has often been associated with some undesirable agronomic *** study the relationship between wheat FHB resistance and agronomic traits,we constructed a linkage map of single nucleotide polymorphisms(SNPs)using an F6:8 population from G97252W*** two hard winter wheat parents showed contrasts in FHB resistance,plant height(HT),heading date(HD),spike length(Sl),spike compactness(SC),kernel number per spike(KNS),spikelet number per spike(SNS),thousand-grain weight(TGW)and grain size(length and width).Quantitative trait locus(QTl)mapping identified one major QTl(***-2DS)on chromosome arm 2DS for the percentage of symptomatic spikelets(PSS)in the spike,deoxynivalenol(DON)content and Fusarium damaged kernel(FDK).This QTl explained up to 71.8%of the phenotypic variation for the three FHB-related traits and overlapped with the major QTl for HT,HD,Sl,KNS,SNS,TGW,and grain *** on chromosome arms 2Al,2DS,3Al and 4BS were significant for the spike and grain traits measured.G97252W contributed FHB resistance and high SNS alleles at ***-2DS,high KNS alleles at the QTl on 2Al and 2DS,and high TGW and grain size alleles at QTl on 3Al;whereas G97380A contributed high TGW and grain size alleles at the QTl on 2Al and 2DS,respectively,and the high KNS allele at the 4BS *** ***-2DS with positive alleles for spike and grain traits from other chromosomes may simultaneously improve FHB resistance and grain yield in new cultivars.

关键词： Wheat Fusarium head blight FHB resistance Developmental and yield traits Pleiotropic QTl

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Oxidized low density lipoprotein(Ox-lDl) impacts on erythrocyte viscoelasticity and its molecular mechanism

Oxidized low density lipoprotein(Ox-LDL) impacts on erythroc...

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第九届全国生物力学学术会议

作者： K.-l.Paul Sung lanping amy Sung Key laboratory of Biorheological Science and Technology(Chongqing University) Ministry of EducationCollege of BioengineeringChongqing University Department of Bioengineering University of CaliforniaSan DiegoLa JollaCA 92093-0412USA

Aim:The oxidized low-density lipoprotein(Ox-lDl) plays an important role in atherosclerosis yet it remains unclear if it damages circulating ***:In this study,erythrocyte deformability and its membrane proteins after OxlDl incubations are investigated by micropipette aspiration,thiol radical measurement and sodium dodecyl sulphate-

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Vision Screening in the Pediatrician’s Office

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Open Journal of Ophthalmology 2012年第2期2卷 9-13页

作者： Natario l. Couser Fatema Q. Esmail amy K. Hutchinson The Department of Ophthalmology Emory University School of Medicine Atlanta USA.

Objective: To assess current practices, attitudes, and perceived barriers toward pediatric vision screening. Patients and Methods: A link to a 9-question survey was electronically distributed to a national sample of 6000 pediatricians through Medical Marketing Services Inc. Data were collected using Survey Monkey. Results: Email open rate was 11%;37% of those who opened the email responded (225 respondents). Over ninety percent of respondents perform some type of vision screening at least yearly, although age at which screening began varied, with two thirds of respondents instituting formal vision screening after three years. Fifty eight percent of respondents were either extremely unsatisfied, unsatisfied or only somewhat satisfied with their current screening method. Preferred methods of screening and confidence of pediatricians in their ability to detect pathology varied for children under versus over age three. The least frequently used methods for all age groups were autorefraction and photoscreening. The most commonly reported barriers to screening were inadequate training (48%), time required for exam (42%), and inadequate reimbursement (32%). Conclusions: Perceived barriers to vision screening in the pediatrician office have been previously identified, and photoscreening and autorefraction have been identified as a possible means to circumvent them. In spite of the addition of new procedural codes, pediatricians continue to report similar barriers to screening.

关键词： Pediatric Vision Screening Barriers Reimbursement Pediatricians Photoscreening Autorefraction U.S. Preventative Services Task Force CPT 99174

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融合与嬗变:世界多国创新创业教育的比较与镜鉴——访澳大利亚南昆士兰大学科林·琼斯博士

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中国电化教育 2020年第9期 105-111页

作者：党建宁 [英国]amy Gerrard 兰州财经大学创新创业学院甘肃兰州730000 英国利物浦约翰摩尔斯大学创业中心英国利物浦L33AF

在全球一体化的背景下,创新驱动发展和支持大众创新创业的中国理念已经得到了国际社会的普遍认可,创新创业教育作为服务创新型国家建设、培养学生创新精神和实践能力的重要举措,也已得到了世界各国的高度重视。该文通过访谈澳大利亚南... 详细信息

在全球一体化的背景下,创新驱动发展和支持大众创新创业的中国理念已经得到了国际社会的普遍认可,创新创业教育作为服务创新型国家建设、培养学生创新精神和实践能力的重要举措,也已得到了世界各国的高度重视。该文通过访谈澳大利亚南昆士兰大学科林·琼斯博士,对澳英美等世界多国与中国的创新创业教育的发展趋势、教育理念和政策环境等进行了比较研究,进一步厘清了其概念内涵、教师成长策略和人才培养路径等问题,对“中国梦”图景下的创新创业教育、创新创业教育者和学习者的“初心”理念,以及多元文化背景下的政策鉴析与路径甄选等,进行了深入探究,以期为我国创新创业教育改革提供相应的借鉴。科林·琼斯(Colin Jones)博士,是南昆士兰大学(University of Southern Queensland)从事学术发展的副教授,同时也是高等教育的主要研究员,在英国威尔士大学、圣大卫三一学院和我国东北师范大学、吉林体育大学(中国)等院校担任创业学习领域的客座教授,提供关于培养和发展具有创业精神的毕业生的建议和指导。此前曾在澳大利亚昆士兰科技大学(Queensland University of Technology)和塔斯马尼亚大学(University of Tasmania)任教20多年,负责设计和讲授创新创业项目,也是世界领先的转型学习和教育评估专家之一。他的研究和教学领域主要聚焦于创业与创业教育,先后出版发表了100多篇/本学术著作,涵盖了40多种国际期刊,他的两本主要著作《本科生创业教育》和《研究生创业教育》均被翻译成中文出版,同时琼斯博士也有着经营多个行业的实际业务的创业经历,开展了多项与初创企业家和创业公司的合作,并为许多政府和国际组织如联合国和世界企业家论坛等提供咨询。

关键词：创新创业教育专创融合创业文化创业政策

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