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Analysis of driving forces behind diversified carbon dioxide emission patterns in regions of the mainland of China

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Frontiers of Environmental Science & Engineering 2011年第3期5卷 445-458页

作者： Xin TIAN Hidefumi IMURA Miao CHANG Feng SHI hiroki TANIKAWA Graduate School of Environmental Studies Nagoya UniversityNagoya 464-8601Japan School of Environment Tsinghua UniversityBeijing 100084China

China has large regional disparities in carbon dioxide CO_(2) emissions with economic development among its 31 provincial mainland *** paper investigates these disparities in CO_(2) emission patterns and identifies the factors underlying the *** show that the 30 study China's mainland provinces(Tibet not included)can be divided into seven groups with three typical CO_(2) emission *** decomposition results indicate that changes in economic development,the industrial sector,and technology contribute far more to increased CO_(2) emissions than do population,energy structure,and other *** inspection reveals that different industry structures and technology contribute greatly to the differences observed in CO_(2) emissions between provinces with similar economic *** study highlights the importance of region-specific industrial structure adjustment policies,especially for regions transitioning to heavy industry and for those still in the primary stages of *** potential application of a domestic carbon emissions trading system,to encourage regional investment in updated technology,is also discussed.

关键词： carbon dioxide emission patterns China economic development index decomposition analysis industrialization

Regulation of CTNNB1 signaling in gastric cancer and stem cells

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World Journal of Gastrointestinal Oncology 2016年第8期8卷 592-598页

作者： Shihori Tanabe Kazuhiko Aoyagi Hiroshi Yokozaki hiroki Sasaki Division of Risk Assessment Biological Safety Re-search Center National Institute of Health ScienceTokyo Department of Translational Oncology National Cancer Center Research InstituteTokyo Department of Pathology Kobe University of Graduate School of Medicine

Recent research has shown that the alteration of combinations in gene expression contributes to cellular phenotypic changes. Previously, it has been demonstrated that the combination of cadherin 1 and cadherin 2 expression can identify the diffuse-type and intestinal-type gastric cancers. Although the diffuse-type gastric cancer has been resistant to treatment, the precise mechanism and phenotypic involvement has not been revealed. It may be possible that stem cells transform into gastric cancer cells, possibly through the involvement of a molecule alteration and signaling mechanism. In this review article, we focus on the role of catenin beta 1 (CTNNB1 or β-catenin) and describe the regulation of CTNNB1 signaling in gastric cancer and stem cells.

关键词： CTNNB1 signaling &beta -catenin Epithelial-mesenchymal transition Gastric cancer Stem cell

Exploitation of shape memory alloy actuator using resistance feedback control and its development

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Progress in Natural Science:Materials International 2010年第1期20卷 97-103页

作者： hiroki CHO Takaei YAMAMOTO Yuji TAKEDA Akihiko SUZUKI Toshio SAKUMA Faculty of Engineering Oita University700 DannoharuOita 870-1192Japan TAKE R&D 2-7-27UmedaKasukabeJapan

The relationship between phase transformation and electric resistivity of Ti-42.6Ni-7Cu SMA was *** the isothermal tensile tests,stress-strain curve shows large hysteresis and nonlinearity,whereas the resistivity-strain curve can be fitted by *** resistivity of SMAs can be determined from the volume fractions of the martensitic and austenitic *** characteristics leads to that the resistance of the SMAs is used as a parameter of strain of SMAs.A SMA actuator using resistance feedback control system was proposed,which can control and retain positioning at any positions without using sensor devices,and the deviation of position of this system was less than 3 μm.

关键词： Ti-Ni-Cu alloy shape memory alloy resistivity shape memory characteristics phase transformation

Potential antioxidant bioactive peptides from camel milk proteins

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Animal Nutrition 2018年第3期4卷 273-280页

作者： Hisham R.Ibrahim hiroki Isono Takeshi Miyata Department of Biochemistry and Biotechnology Faculty of Agriculture Kagoshima University

Camel milk is traditionally considered to have medicinal characteristics that it has potential health benefits and could help to treat several illnesses. Particularly, it is closest to human breast milk and has high levels of nutrients and bioactive components. The aim of this study was to explore the antioxidant peptides derived from protein fractions of camel milk. Camel milk proteins(CMP) were fractionated into camel casein protein(CCP) and camel whey protein(CWP), which were hydrolyzed with pepsin to produce peptic digests P-CCP and P-CWP, respectively. RP-HPLC was used for fractionation of the peptides from the P-CCP and P-CWP. The antioxidant activities were evaluated using superoxide anion generating system of xanthine oxidase(XOD)and 2,2-diphenyl-1-picrylhydrazyl(DPPH) scavenging assay. Active peptides were analyzed using matrixassisted laser desorption ionization time of flight mass spectrometry(MALDI-TOF-MS) whereas a number of antioxidant peptides, with masses ranging from 913 to 2,951 Da, derived mainly from alpha-casein, lactophorin and lactoferrin, were identified. When yeast cells are used as a system for modeling mitochondrial disease, the peptides in caseins and whey fractions significantly enhanced the tolerance of yeast cells against peroxide-induced oxidative stress. The results show that both caseins and whey proteins of camel milk possess bioactive peptides with significant radical-scavenging activities and thus herald a fascinating opportunity for their potential as nutraceuticals or therapeutic peptides for prevention and treatment of oxidative stress-associated diseases.

关键词： Camel milk proteins Antioxidant Bioactive peptides Superoxide scavenging Yeast tolerance

Genotype-Phenotype Correlations in Ornithine Transcarbamylase Deficiency: A Mutation Update

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Journal of Genetics and Genomics 2015年第5期42卷 181-194页

作者： Ljubica Caldovic Iman Abdikarim Sahas Narain Mendel Tuchman hiroki Morizono Department of Integrative Systems Biology Center for Genetic Medicine Research Children's National Health System Department of Anthropology College of Arts and Sciences Washington University Graduate School of Biomedical Sciences and Professional Studies College of Medicine Drexel University

Ornithine transcarbamylase （OTC） deficiency is an X-linked trait that accounts for nearly half of all inherited disorders of the urea cycle. OTC is one of the enzymes common to both the urea cycle and the bacterial arginine biosynthesis pathway; however, the role of OTC has changed over evolution. For animals with a urea cycle, defects in OTC can trigger hyperammonemic episodes that can lead to brain damage and death. This is the fifth mutation update for human OTC with previous updates reported in 1993, 1995, 2002, and 2006. In the 2006 update, 341 mutations were reported. This current update contains 417 disease-causing mutations, and also is the first report of this series to incorporate information about natural variation of the OTC gene in the general population through examination of publicly available genomic data and examination of phenotype/genotype correlations from patients participating in the Urea Cycle Disorders Consortium Longitudinal Study and the first to evaluate the suitability of systematic computational approaches to predict severity of disease associated with different types of OTC mutations.

关键词： Ornithine transcarbamylase Mutation Ornithine transcarbamylase deficiency Urea cycle Hyperammonemia

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曹村废弃矿山防治工程设计研究

曹村废弃矿山防治工程设计研究

作者： ago Able Mardochee 绍兴文理学院

学位级别：硕士

随着社会经济的快速发展,城乡建设正迎来前所未有的提升。在此基础上,矿产资源的开发就显得尤为重要,因为矿产资源的开发为我国经济建设提供了大量的物质和能源基础,是推动中国经济建设的强大力量。但是,大量的采矿作业造成了土地资源... 详细信息

随着社会经济的快速发展,城乡建设正迎来前所未有的提升。在此基础上,矿产资源的开发就显得尤为重要,因为矿产资源的开发为我国经济建设提供了大量的物质和能源基础,是推动中国经济建设的强大力量。但是,大量的采矿作业造成了土地资源破坏、水环境干扰、矿山次生灾害、景观和生态破坏等一系列环境问题。而且,早期大量的不规范开采作业对矿山生态环境造成了永久性的破坏;在经济建设的背景下,矿产资源的开发进程是不可阻挡的,因此中国矿山的可持续发展显得尤为重要。虽然矿山生态修复也在快速发展,但目前使用的矿山生态修复理论和技术仍存在一定的局限性。特别是在矿山现场地形地貌的实时测量中,仍采用较为传统的方法。因此,本研究以曹村废弃矿山为研究对象,引入无人机倾斜摄影测量技术,作为一项足够的技术,弥补勘探采矿地形数据处理的不足。首先对矿山生态修复的概念进行了界定,并对矿山生态修复领域存在的问题和未来的发展趋势进行了探讨。同时阐述了无人机倾斜摄影测量产生真实三维空间模型的过程和原理,并对其应用领域和发展潜力进行了论证。此外,我们提出了从三维点云中自动识别和表征岩体中结构面的一种新的方法,该方法基于4个步骤:（1）使用迭代法向量计算再加权平面拟合（IRPF）方法,（2）结构面集集群的快速搜索和发现密度峰值（CFSFDP）算法,和费雪的K值迭代计算消除噪声点,（3）结构面分割使用基于密度比的方法,并使用随机结构面拟合样本共识（RANSAC）算法,（4）持久性和间距计算利用解析几何理论。最后,本文也提出了矿山生态恢复的设计方法,研究总结了无人机倾斜摄影测量和提出的三维点云的岩体结构面自动识别和表征方法相对于传统测量方法的优势,即更具灵活性、高效性,降低了勘察和预防设计过程的成本和时间消耗。

关键词：矿山生态修复无人机倾斜摄影灾害防治 3D点云岩体节理

Endoscopic ultrasound-guided fine-needle aspiration biopsy-Recent topics and technical tips

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World Journal of Clinical Cases 2019年第14期7卷 1775-1783页

作者： Kazuya Matsumoto Yohei Takeda Takumi Onoyama Soichiro Kawata hiroki Kurumi hiroki Koda Taro Yamashita Hajime Isomoto Division of Internal Medicine Irisawa Medical ClinicMatsue 690-0025Japan Department of Multidisciplinary Internal Medicine Tottori UniversityYonago 683-8504Japan

Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) is a useful procedure that enables reliable pathological diagnoses of pancreatobiliary diseases, subepithelial lesions, and swollen lymph nodes. In recent years, a pathological diagnosis based on EUS-FNA has made it possible to provide accurate treatment methods not only in these fields, but also in respiratory organs and otorhinolaryngology. This review discusses the latest topics pertaining to EUS-FNA as well as procedural tips.

关键词： Endoscopic ultrasound-guided fine-needle aspiration biopsy Cytology Pathology Pancreatobiliary diseases Subepithelial lesions Lymph nodes

The right hepatic artery syndrome

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World Journal of Gastroenterology 2005年第19期11卷 3008-3009页

作者： Kazumi Miyashita Katsuya Shiraki Takeshi Ito hiroki Taoka Takeshi Nakano First Department of Internal Medicine Mie University School of Medicine TsuMie 514-8507Japan First Department of Surgery Mie University School of Medicine TsuMie 514-8507Japan

Various benign and malignant conditions could cause biliary obstruction. Compression of extrahepatic bile duct (EBD) by right hepatic artery was reported as a right hepatic artery syndrome but all cases were compressed EBD from stomach side. Our case compressed from dorsum was not yet reported, so it was thought to be a very rare case. We present here the first case of bile duct obstruction due to the compression of EBD from dorsum by right hepatic artery.

关键词： Right hepatic artery syndrome Obstructive jaundice Extrahepatic bile duct Right hepatic artery Endoscopic retrograde cholangiography Cholangioen-terostomy

Genomics in Space Life Sciences

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Genomics, Proteomics & Bioinformatics 2008年第1期6卷 1-3页

作者： Jade Q. Clement hiroki Yokota Department of Chemistry and NASA University Research Center for Biotechnology and Environmental Health Texas Southern UniversityHouston TX 77004 USA Department of Biomedical Engineering / Department of Anatomy and Cell Biology Indiana University-Purdue University IndianapolisIndianapolis IN 46202 USA

Since the early days of manned spaceflight, hazardous effects of the space environment on living organisms have been disputed. With the continuous manning of the International Space Station, the planned Chinese space station, and renewed interest in returning to the Moon and sending manned flights to Mars, identifying and addressing the potential outcomes of long-term space exposures is critically important.

关键词： gene Genomics in Space Life Sciences