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Round Robin Study on the Thermal Conductivity/Diffusivity of a Gold Wire with a Diameter of 30μm Tested via Five Measurement Methods

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Journal of Thermal Science 2022年第4期31卷 1037-1051页

作者： ABE Ryo SEKIMOTO Yuki SAINI Shirkant MIYAZAKI Koji LI Qin-Yi LI Dawei TAKAHASHI Koji YAGI Takashi NAKAMURA Masakazu division of materials science nara institute of science and technologyikoma 630-0192japan department of mechanical and control engineering kyushu institute of technologykitakyushu 804-8550japan department ofaeronautics and astronautics kyushu universityfukuoka819-0395japan international institute for carbon-neutral energy research(wpi-i2cner) kyushu universityfukuoka 819-0395japan national metrology institute of japan national institute of advanced industrial science and technology tsukuba 305-8565japan

Since first establishing thermal measurement techniques for micrometer-scale wires,various methods have been devised and improved upon.However,the uncertainty of different measurements on the same sample has not yet been discussed.In this work,a round robin test was performed to compare the thermal conductivity and thermal diffusivity measurement methods for a fine metal wire.The tested material was a pure gold wire,with a diameter of 30μm.The wire was cut into certain lengths and distributed to four institutions using five different measurement methods:the direct current(DC)self-heating method,the DC heating T-type method,the 3ωmethod for thermal conductivity,the scanning laser heating alternating current(AC)method,and the spot periodic heating radiation thermometry method for thermal diffusivity.After completing the measurements,the reported thermal conductivity and thermal diffusivity at room temperature,i.e.,317 W·m^(-1)·K^(-1)and 128×10^(-6)m^(2)·s^(-1),respectively,were adopted as references for comparison with the measurement results.The advantages and disadvantages of each method are described in terms of the effect of electrical and thermal junctions fabricated on a wire,such as an electrode,a thermocouple,and a heat bath.The knowledge obtained from the tested methods will be useful for selecting and designing a measurement technique for various wire-like materials.

关键词： thermal conductivity thermal diffusivity round robin test microscale wire

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Liver-targeted hydrodynamic gene therapy: Recent advances in the technique

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World Journal of Gastroenterology 2016年第40期22卷 8862-8868页

作者： Takeshi Yokoo Kenya Kamimura Hiroyuki abe Yuji Kobayashi Tsutomu Kanefuji Kohei Ogawa ryo Goto Masafumi Oda Takeshi Suda Shuji Terai Division of Gastroenterology and Hepatology Graduate School of Medical and Dental Sciences Niigata University Institute for Research Collaboration and Promotion Niigata University

One of the major research focuses in the field of gene therapy is the development of clinically applicable, safe, and effective gene-delivery methods. Since the first case of human gene therapy was performed in 1990, a number of gene-delivery methods have been developed, evaluated for efficacy and safety, and modified for human application. To date, viral-vectormediated deliveries have shown effective therapeutic results. However, the risk of lethal immune response and carcinogenesis have been reported, and it is still controversial to be applied as a standard therapeutic option. On the other hand, delivery methods for nonviral vector systems have been developed, extensively studied, and utilized in in vivo gene-transfer studies. Compared to viral-vector mediated gene transfer, nonviral systems have less risk of biological reactions. However, the lower gene-transfer efficiency was a critical hurdle for applying them to human gene therapy. Among a number of nonviral vector systems, our studies focus on hydrodynamic gene delivery to utilize physical force to deliver naked DNA into the cells in the living animals. This method achieves a high gene-transfer level by DNA solution injections into the tail vein of rodents, especially in the liver. With the development of genome editing methods, in vivo gene-transfer therapy using this method is currently the focus in this research field. This review explains the method principle, efficiency, safety, and procedural modifications to achieve a high level of reproducibility in large-animal models.

关键词：基因治疗肝水动力学基因交货非病毒指导图象

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飞舞空中的粗野派——岛的厨房

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缤纷 2012年第4期 66-71页

作者： ryo abe 韩佳纹 LiLi DAICI ANO

"岛的食堂"是一个质朴却别具匠心的建筑环境更新项目。当然,这并不仅仅是一间迷你食肆,更有为艺术的展示的潜在功能。岛,是西日本濑户内海的环抱中偏远小岛,虽然距离日本著名的艺术旅行名岛——直岛相近,却仍然只是一个保持了浓厚乡土... 详细信息

"岛的食堂"是一个质朴却别具匠心的建筑环境更新项目。当然,这并不仅仅是一间迷你食肆,更有为艺术的展示的潜在功能。岛,是西日本濑户内海的环抱中偏远小岛,虽然距离日本著名的艺术旅行名岛——直岛相近,却仍然只是一个保持了浓厚乡土情趣的村庄。场地中现存旧房子的周围曾经有过一些其他的建筑,但均已经在许久之前拆毁。留存下来的,只有一个破旧的仓库,两颗柿子树,还有个头不大的无花果树在风雨中飘摇。不过,就是在这个一个旧房子和它稀松平常的乡村环境中。

关键词：厨房建筑师住宅建筑周围环境行为艺术设计师乡土气息房子景观材料

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Pulmonary <i>Mycobacterium kansasii</i>Disease with Solitary Nodule

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Journal of Tuberculosis Research 2019年第1期7卷 19-24页

作者： Yoshihiro Kobashi Masaaki abe ryo Shirai Shigeki Kato Department of Respiratory Medicine Kawasaki Medical School Matsushima Japan

We recently encountered two patients with pulmonary Mycobacterium kansasii disease showing a solitary nodule. The patients were 53 and 66 years old and both were male. One patient had underlying diseases. The diagnosis was based on the clinical symptom in one patient and an abnormal chest shadow in the other. The final diagnosis was obtained by bronchoscopy and CT-guided lung biopsy. Antituberculous drugs were administered to one patient. We emphasize the importance of the positive identification of causative microorganisms in patients who present with a solitary nodule including surgical methods to differentiate the infection from lung cancer.

关键词： Pulmonary Mycobacterium kansasii Disease Lung Cancer

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Non-contact Acoustic Contour Imaging Method Using Phase Difference in Extremely Shallow Underground

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Journal of Energy and Power Engineering 2012年第12期6卷 2010-2017页

作者： Tsuneyoshi Sugimoto ryo Akamatsu Touma abe Department of Electronics and Information Faculty of Engineering Toin University of Yokohama Yokohama 225-8503 Japan Inspection Division IHI Inspection & Instrumentation Co. Ltd. Tokyo 140-0014 Japan

Buried object which exists at extremely shallow underground can be detected by using an acoustic vibration and a SLDV (scanning laser Doppler vibrometer). Non-contact acoustic exploration can be realized by using air coupled sound. It was confirmed that discovery and the identification of a buried thing were possible using the OFR method (optimum frequency range method). However, in this method, only the amplitude of the vibration speed spectrum is used and did not use the phase information. Therefore, a new imaging method is proposed that used the phase information of the vibration speed spectrum. From the experimental results, the possibility of the outline extraction by using the phase difference between each scan point is confirmed. As a future task, the phase difference image will become clearer by changing the scan point density and long duration time of emitted wave.

关键词：成像方法非接触式轮廓提取相位差声学相位信息激光多普勒浅层地下水

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An interactive approach to investigate brightness perception of daylighting in Immersive Virtual Environments:Comparing subjective responses and quantitative metrics

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Building Simulation 2022年第1期15卷 41-68页

作者： Muhammad Hegazy Kensuke Yasufuku Hirokazu abe Graduate School of Engineering Osaka UniversityYamadaoka 2-1 Suita Osaka567-0047Japan Cybermedia Center Osaka UniversityJapan

Daylighting plays an eminent role in the performance of indoor environments and their occupants,thus necessitating the need to investigate daylight perception of potential occupants at early design stages.The present study introduces an interactive approach to collect and visualize brightness perception of daylighting in a large-scale immersive virtual environment using a game engine as a daylight simulation tool.The developed system allows users to explore building models freely at different day times set in virtual reality and report their perceptions in real time.Following a validation study(N=36)to investigate the consistency of brightness perceptions in a real environment and its virtual replica,a set of 24 participants were recruited to use the system to report their brightness perception in a virtual model of a daylit art museum,through snapshotting the scenes where they perceive as one of the following in terms of daylighting:(very dark,dark,bright,or very bright).Using an output of 419 snapshots,a"Perceptual Light Map"(PLM)was developed to visualize the collective brightness perception of participants as a heat map.Subjective responses were found to be positively correlated with four daylight metrics,with the highest correlation to mean luminance and the lowest to luminance ratio.The findings of this exploratory study represent a step towards a user-oriented supplement tool to the existing quantitative daylight metrics,validating game engines’adequacy as a daylight simulation tool,and illustrating the potentials of immersion and interaction principles for the perception of daylit spaces in virtual reality.

关键词： immersive virtual environment daylighting game engine human perception mean luminance

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Dilute long period stacking/order(LPSO)-variant phases along the composition gradient in a Mg-Ho-Cu alloy

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Journal of Magnesium and Alloys 2022年第6期10卷 1573-1580页

作者： Kai Guan Daisuke Egusa Eiji abe Department of Materials Science and Engineering The University of TokyoTokyo 113-8656Japan Research Center for Structural Materials National Institute for Materials ScienceTsukuba 305-0047Japan

We have systematically investigated the microstructures of as-cast Mg_(97.49)Ho_(1.99)Cu_(0.43)Zr_(0.09)alloy by atomic resolution high-angle annular dark field scanning transmission electron microscopy(HAADF-STEM), revealing the coexistence of 18R, 14H and 24R long period stacking/order(LPSO) phases with fully coherent interfaces along step-like composition gradient in a blocky intermetallic compound distributed at grain boundary. The short-range order(SRO) L1_(2)-type Cu_(6)Ho_(8)clusters embedded across AB’C’A-stacking fault layers are directly revealed at atomic scale. Importantly, the order degree of SRO clusters in the present dilute alloy is significant lower than previous 6M and 7M in-plane order reported in ternary Mg-TM(transition metal)-RE(rare earth) alloys, which can be well matched by 9M in-plane order. This directly demonstrates that SRO in-plane L1_(2)-type clusters can be expanded into more dilute composition regions bounded along the definite TM/RE ratio of 3/4. In addition, the estimated chemical compositions of solute enriched stacking fault(SESF) in all LPSO variants are almost identical with the ideal SESF composition of 9M in-plane order, regardless of the type of LPSO phases. The results further support the viewpoint that robust L1_(2)-type TM_(6)RE_(8)clusters play an important role in governing LPSO phase formation.

关键词： Magnesium alloys Long period stacking/order(LPSO)phases Short-range order(SRO)clusters High-angle annular dark field scanning transmission electron microscopy(HAADF-STEM)

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Effects of Etelcalcetide on Bone Microstructure in the Adenine-Induced Chronic Kidney Disease Rat Model

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Open Journal of Orthopedics 2023年第12期13卷 509-524页

作者： Shun Igarashi Yuji Kasukawa Koji Nozaka Hiroyuki Tsuchie Kazunobu abe Hikaru Saito ryo Shoji Fumihito Kasama Shuntaro Harata Kento Okamoto Keita Oya Naohisa Miyakoshi Department of Orthopedic Surgery Akita University Graduate School of Medicine Akita Japan Department of Rehabilitation Medicine Akita University Hospital Akita Japan

Objective: Chronic kidney disease (CKD) with secondary hyperparathyroidism (SHPT) increases the risk of fragility fractures with deterioration of cortical and trabecular bone microstructure. Etelcalcetide (EC), which is used to treat SHPT, reduces parathyroid hormone (PTH) levels in the blood. However, the details of the effects of EC on the microstructure of cortical and trabecular bone remain unclear. This study investigated whether EC improved the cortical and trabecular bone microstructure in CKD model rats. Methods: Eight-week-old, male Wistar rats were fed with a 0.75% adenine diet for 4 weeks to establish the CDK model rats. At 20 weeks of age, the rats were divided into two groups (n = 9 - 11 in each group): CKD group (vehicle administration) and EC group (0.6 mg/kg, daily). EC was injected for 4 weeks starting at 20 weeks of age. After treatment, the biochemical tests, measurement of bone mineral density and bone strength, and evaluation of cortical and trabecular bone microstructure were performed. Results: Compared with the CKD group, the EC group showed significantly lower serum blood urea nitrogen, calcium, and inorganic phosphorus levels (p p p p p Conclusions: EC significantly improved cortical microstructure and cortical porosity, suppressing deterioration of cortical bone strength and loss of trabecular bone in the adenine-induced CKD model rats.

关键词： Chronic Kidney Disease Secondary Hyperparathyroidism Osteoporosis Etelcalcetide

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Quantitative classification of Camellia japonica and Camellia rusticana(Theaceae)based on leaf and flower morphology

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Plant Diversity 2021年第3期43卷 216-224页

作者： Harue abe Hiroki Miura Yoshitaka Motonaga Center for Sustainable Agriculture and Forestry Faculty of AgricultureNiigata University94-2 KodaSadoNiigata952-2206Japan Aomori Prefectural Asamushi Aquarium 1-25 BabayamaAsamushiAomoriAomori039-3501Japan Faculty of Agriculture Niigata University8050 Ikarashi-ninochoNishi-kuNiigata950-2181Japan

In Japan,Camellia japonica and Camellia rusticana are naturally distributed.Despite differences in their habitats and morphologies,they have been classified by various researchers as either varieties,subspecies,or species.The taxonomic position of C.japonica and C.rusticana remain unclear because morphological comparisons have been restricted to limited areas and quantitative data are scarce.C.rusticana grows in snowy places,unlike C.japonica.While C.japonica displays ornithophily,C.rusticana displays entomophily.Both species have adapted to different growing environments and pollinators,which have altered the morphology of flowers and leaves.We therefore quantitatively estimated the differentiation between these two taxa by comparing the morphologies of leaf hypodermis,flower form,petal color,and filament color in twenty populations.Our findings allowed us to differentiate these two species by the presence or absence of a leaf hypodermis.We also discovered an intermediate type of leaf hypodermis,which might also be caused by hybridization.Principal component analysis(PCA)indicated that the flower morphologies between these species were significantly different.The petal and filament colors were also significantly different.Our quantitative analysis suggests that speciation caused by differences in both pollinators and environment is one of the factors involved in this group.These findings in C.japonica and C.rusticana help to explain speciation processes for other species as well.

关键词： Camellia japonica Camellia rusticana Ecological isolation Pollinator shift Pollination syndrome Reproductive isolation

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Current overview on the genetic basis of key genes involved in soybean domestication

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aBIOTECH 2022年第2期3卷 126-139页

作者： Sijia Lu Chao Fang Jun abe Fanjiang Kong Baohui Liu Innovative Center of Molecular Genetics and Evolution School of Life SciencesGuangzhou UniversityGuangzhou 510006China Guangzhou Key Laboratory of Crop Gene Editing Guangzhou UniversityGuangzhou 510006China Research Faculty of Agriculture Hokkaido UniversitySapporoHokkaido 060-0808Japan

Modern crops were created through the domestication and genetic introgression of wild relatives and adaptive differentiation in new environments.Identifying the domestication-related genes and unveiling their molecular diversity provide clues for understanding how the domesticated variants were selected by ancient people,elucidating how and where these crops were domesticated.Molecular genetics and genomics have explored some domestication-related genes in soybean(Glycine max).Here,we summarize recent studies about the quantitative trait locus(QTL)and genes involved in the domestication traits,introduce the functions of these genes,clarify which alleles of domesticated genes were selected during domestication.A deeper understanding of soybean domestication could help to break the bottleneck of modern breeding by highlighting unused genetic diversity not selected in the original domestication process,as well as highlighting promising new avenues for the identification and research of important agronomic traits among different crop species.

关键词： Soybean Domestication Diversity Gene

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