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Aptamer based detection and separation platforms for ochratoxin A:A systematic review

BIOCELL 2022年第12期46卷 2537-2557页

作者： RAHELEH TORABI abbas ali rezvanipour HADI ESMAEILI GOUVARCHINGHALEH REZA RANJBAR MOHAMMAD HEIAT Laboratory of Bioanalysis Institute of Biochemistry&BiophysicsUniversity of TehranTehranIran Baqiyatallah Research Center for Gastroenterology and Liver Diseases(BRCGL) Baqiyatallah University of Medical SciencesTehranIran Applied Virology Research Center Baqiyatallah University of Medical SciencesTehranIran Molecular Biology Research Center Systems Biology and Poisonings InstituteBaqiyatallah University of Medical SciencesTehranIran

Ochratoxin A(OTA),one of the most dangerous mycotoxins for human health,has been subjected to numerous studies for separation and detection in minimal *** as novel recognition elements have been employed to fabricate ultrasensitive biosensors for the detection of OTA and designing delicate analytical *** review attempted to comprehensively examine all reported aptamer-based detection and separation platforms for *** most relevant databases were considered to discover all specific aptamers for dealing with ***-based detection and separation devices specified for OTA were searched for,analyzed,discussed,and classified based on their *** optical aptasensors have gathered a higher interest than electrochemical aptasensors,which can achieve a lower limit of ***,some extraction platforms based on these aptamers were also ***,aptamer-based devices seem to have some challenges in their application.

关键词： Aptamer Aptasensors Ochratoxin A Mycotoxin Biosensor

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Central composite design for optimization and formulation of desulphurization of iron ore concentrate using atmospheric leaching process

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Journal of Iron and Steel Research International 2018年第1期25卷 57-64页

作者： ali Mostafavi Hassan rezvanipour Dariush Afzali Tayebeh Shamspur Amir Hajizadehomran Department of Chemistry Shahid Bahonar Universityof Kerman Kerman 84156-83111 Iran Gol-e-Gohar Iron Ore Mining and Industrial Company Sirjan Km 50 of Shiraz road 111/78185 Kerman Iran Department of Environment Institute of Science and HighTechnology and Environmental Sciences GraduateUniversity of Advanced Technology Kerman 76311-33131Iran

Owing to the negative effects of sulphur in iron ore on steelmaking process and environment, a tank leaching process was performed in atmospheric conditions to remove the sulphur from the iron ore concentrate and simultaneously to transform sulphide minerals into useful by-products. To achieve desirable sulphur removal rate and efficiency, central composite design was adopted as a response surface methodology for the optimization and evaluation of the process. A full-quadratic polynomial equation between the sulphur removal and the studied parameters was established to assess the behaviour of sulphur removal as a function of the factors and to predict the results in various conditions. The optimum conditions were obtained based on the variance tests and response surface plots, from which the optimized ranges for each factor resulting in the best response （corresponding to the highest percentage of desulphurization） could be then achieved. The results show that most desirable conditions are atmospheric leaching in 1.39 mol/dm3 nitric acid and 0.88 mol/dm3 sulphuric acid for 47 h. The designed process under the optimized desulphurization conditions was applied to a real iron ore concentrate. More than 75% of the total sulphur was removed via the leaching process. In addition to the desulphurization, the conversion of sulphide-bearing minerals into useful by-products, extraction of valuable metals, and executing the process under atmospheric conditions are the other advantages of the proposed method.

关键词： Desulphurization Iron ore concentrate Sulphide mineral leaching Central composite design Atmosphericleaching process

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