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A child with Erysipelothrix-beware of the little known

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Asian Pacific Journal of Tropical Biomedicine 2012年第6期2卷 503-504页

作者： Chiranjay Mukhopadhyay Hitesh Shah KE Vandana Frenil Munim Sandeep vijayan Department of Microbiology Kasturba Medical College Manipal University Department of Orthopaedics Kasturba Medical College Manipal University

Erysipelothrix rhusiopathiaeis an established animal pathogen while the zoonotic infections in humans are rarely reported. Infections occur after exposure to animals or animal products that are mostly occupational in adults. Here we report in a child for the first time septic arthritis and osteomyelitis without an identifiable risk factor. A 5-year-old male child was admitted with pain in the left hip joint and inability to bear weight on the limb. Clinical examination followed by radiological and magnetic resonance imaging was suggestive of septic *** rhusiopathiaegrew from peroperative joint specimen. The infection was resolved following arthrotomy, joint lavage and antibiotic therapy.

关键词： Erysipelothrix rhusiopathiae Osteomyelitis Septic arthritis

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小冰淇淋店的物联网

市场营销（实务版） 2010年第10期

作者： Jaikumar vijayan

来源：人大复印报刊资料评论

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鞘氨醇激酶1调控麻疹病毒的复制

微生物与感染 2014年第4期9卷 260-260页

作者： vijayan M

麻疹病毒（MV）可操纵宿主因素以促进病毒复制。鞘氨醇激酶（SK）能催化鞘氨醇‐1‐磷酸的形成和调节多种细胞过程，包括宿主防御系统。该研究确定了SK1在MV复制中的作用。过表达SK1增强MV复制。与此相反，抑制SK病毒蛋白表达受损，表... 详细信息

麻疹病毒（MV）可操纵宿主因素以促进病毒复制。鞘氨醇激酶（SK）能催化鞘氨醇‐1‐磷酸的形成和调节多种细胞过程，包括宿主防御系统。该研究确定了SK1在MV复制中的作用。过表达SK1增强MV复制。与此相反，抑制SK病毒蛋白表达受损，表达MV受体（SLAM或Nectin‐4）的细胞中感染性病毒生产减少。这种抑制现象在细胞感染了疫苗菌株或野生型或V／C基因缺损的MV后均被观察到。重要的是，抑制SK活性能抑制MV诱导的核因子κB（NF‐κB）活化。NF‐κB信号通路抑制剂可抑制MV蛋白合成，揭示NF‐κB活化对有效MV复制的重要性。因此，抑制SK能限制MV复制并调节NF‐κB信号通路，提示SK是MV复制的关键细胞因子。

关键词：鞘氨醇激酶病毒复制麻疹病毒细胞因子调控信号通路核因子κB 防御系统

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小企业账户网络犯罪日益增加

软件世界 2009年第10期 25-25页

作者： Jaikumar vijayan 赵军

小银行和企业正在遭受日益增多的网络攻击浪潮，犯罪分子们通过盗取银行认证证书盗取公司帐户中的钱。

关键词：小企业网络犯罪账户网络攻击认证证书犯罪分子银行

State of deceased donor transplantation in India:A model for developing countries around the world

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World Journal of Transplantation 2016年第2期6卷 331-335页

作者： Georgi Abraham Madhusudan vijayan Natarajan Gopalakrishnan Sunil Shroff Joseph Amalorpavanathan Anand Yuvaraj Sanjeev Nair Saravanan Sundarrajan Madras Medical Mission Hospital Kilpauk Medical College Madras Medical College and Government General Hospital

Renal replacement therapy(RRT) resources are scarce in India, with wide urban-rural and interstate disparities. The burden of end-stage renal disease is expected to increase further due to increasing prevalence of risk factors like diabetes mellitus. Renal transplantation, the best RRT modality, is increasing in popularity, due to improvements made in public education, the deceased donor transplantation(DDT) programme and the availability of free and affordable transplant services in government hospitals and certain non-governmental philanthropic organizations. There are about 120000 haemodialysis patients and 10000 chronic peritoneal dialysis patients in India, the majority of them waiting for a donor kidney. Shortage of organs, lack of transplant facilities and high cost of transplant in private facilities are major barriers for renal transplantation in India. The DDT rate in India is now 0.34 per million population, among the lowest in the world. Infrastructural development in its infancy and road traffic rules not being strictly implemented by the authorities, have led to road traffic accidents being very common in urban and rural India. Many patients are declared brain dead on arrival and can serve as potential organ donors. The DDT programme in the state of Tamil Nadu has met with considerable success and has brought down the incidence of organ trade. Government hospitals in Tamil Nadu, with a population of 72 million, provide free transplantation facilities for the underprivileged. Public private partnership has played an important role in improving organ procurement rates, with the help of trained transplant coordinators in government hospitals. The DDT programmes in the southern states of India(Tamil Nadu, Kerala, Pondicherry) are advancing rapidly with mutual sharing due to public private partnership providing vital organs to needy patients. Various health insurance programmes rolled out by the governments in the southern states are effective in alleviatin

关键词： Deceased donor transplantation Kidney India Developing countries

TNC 2021年度全球摄影大赛获奖名单出炉(下)

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科学中国人 2021年第30期 64-64,F0003页

作者： [比利时]Alain Schroeder(摄) [澳大利亚]Tom Overall(摄) [土耳其]Sebnem Coskun(摄) [捷克共和国]Viktor Vrbovsky(摄) Minqiang Lu(摄) [加拿大]Thomas vijayan(摄) [哥伦比亚]Kristhian Castro(摄) [英国]Anup Shah(摄) 不详

日前,大自然保护协会(TNC)2021年度全球摄影大赛落下帷幕。大赛期间,共收到来自158个国家和地区超过10万张摄影作品,并选出了特等奖、人民选择奖和各组别获奖作品。下面,就请大家欣赏一下此次大赛的优秀作品吧!

关键词：摄影大赛大自然保护摄影作品 TNC 获奖作品优秀作品获奖名单全球

Choice of wound care in diabetic foot ulcer: A practical approach

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World Journal of Diabetes 2014年第4期5卷 546-556页

作者： Karakkattu vijayan Kavitha Shalbha Tiwari Vedavati Bharat Purandare Sudam Khedkar Shilpa Sameer Bhosale Ambika Gopalakrishnan Unnikrishnan Podiatry Department Chellaram Diabetes Institute Pune 411021 India Research Department Chellaram Diabetes In-stitute Pune 411021 India Diabetes and Endocrinology Department Chellaram Diabetes Institute Pune 411021 India

Diabetic foot ulcers are the consequence of multiple factors including peripheral neuropathy,decreased blood supply,high plantar pressures,etc.,and pose a significant risk for morbidity,limb loss and *** critical aspects of the wound healing mechanism and host physiological status in patients with diabetes necessitate the selection of an appropriate treatment strategy based on the complexity and type of *** addition to systemic antibiotics and surgical intervention,wound care is considered to be an important component of diabetic foot ulcer *** article will focus on the use of different wound care materials in diabetic *** a clinical perspective,it is important to decide on the wound care material depending on the type and grade of the *** article will also provide clinicians with a simple approach to the choice of wound care materials in diabetic foot ulcer.

关键词： Diabetes Foot Wound Debridement Topical

Growth, Optical, Mechanical, Thermal and Second Harmonic Generation （SHG） of N-methyl Urea Doped Benzimidazole Single Crystal Grown by VBT

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材料科学与工程（中英文A版） 2013年第12期3卷 806-813页

作者： Riscob Bright Manayi Koodathingal Raseel Rahman Mohammad Shkir Narayanasamy vijayan DavidsonSajan Mohammad Margub Abdullah Godavarthi Bhagavannarayana Mohammad Abdul Wahab Institute for Plasma Research Bhat Gandhinagar 382 428 Gujarat India Department of Physics Bishop Moore College Mavelikara 690 110 Kerala India Crystal Growth Lab Departmento de Fisica de Materiales Universidad A utonoma de Madrid Madrid Spain-28049 CSIR-National Physical Laboratory New Delhi-12 India Promising Centre for Sensors and Electronic Devices (PCSED) Department of Physics Najran University PO Box 1988Najran- l l O01 Saudi Arabia Crystal Growth & XRD Lab Dept. of Physics Jamia Millia Islamia New Delhi-25 India

N-methylurea doped benzimidazole single crystals were grown by vertical Bridgman technique (VBT) for the first time. The grown crystals were subjected to powder X-ray diffraction analysis for the confirmation of crystal system and lattice parameter. The transmission spectrums were recorded for both crystals and found that the doped crystal has more transparency than the pure. The photoluminescence study was carried out by using PL spectrophotometer and mechanical strength has been analyzed by Vicker"s hardness tester. The laser damage threshold results and relative second harmonic generation efficiency studies reveals doped sample is showing better performance for nonlinear optical applications. Thermal studies clearly indicate about the stability of pure and doped samples at higher temperature regions.

关键词：二次谐波产生掺杂晶体苯并咪唑类 N-甲基脲光学应用生长单晶 SHG

Inhaled hypertonic saline for cystic fibrosis: Reviewing the potential evidence for modulation of neutrophil signalling and function

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World Journal of Critical Care Medicine 2015年第3期4卷 179-191页

作者： Emer P Reeves Cormac McCarthy Oliver J McElvaney Maya Sakthi N vijayan Michelle M White Danielle M Dunlea Kerstin Pohl Noreen Lacey Noel G McElvaney Respiratory Research Division Department of Medicine Royal College of Surgeons in Ireland Beaumont Hospital

Cystic fibrosis(CF) is a multisystem disorder with significantly shortened life expectancy. The major cause of mortality and morbidity is lung disease with increasing pulmonary exacerbations and decline in lung function predicting significantly poorer outcomes. The pathogenesis of lung disease in CF is characterised in part by decreased airway surface liquid volume and subsequent failure of normal mucociliary clearance. This leads to accumulation of viscous mucus in the CF airway, providing an ideal environment for bacterial pathogens to grow and colonise, propagating airway inflammation in CF. The use of nebulised hypertonic saline(HTS) treatments has been shown to improve mucus clearance in CF and impact positively upon exacerbations, quality of life, and lung function. Several mechanisms of HTS likely improve outcome, resulting in clinically relevant enhancement in disease parameters related to increase in mucociliary clearance. There is increasing evidence to suggest that HTS is also beneficial through its anti-inflammatory properties and its ability to reduce bacterial activity and biofilm formation. This review will first describe the use of HTS in treatment of CF focusing on its efficacy and tolerability. The emphasis will then change to the potential benefits of aerosolized HTS for the attenuation of receptor mediated neutrophil functions, including down-regulation of oxidative burst activity, adhesion molecule expression, and the suppression of neutrophil degranulation of proteolytic enzymes.

关键词： Cystic fibrosis Hypertonic saline Mucociliary clearance Neutrophils and inflammation