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Frontiers of Structural and Civil Engineering 2024年第1期18卷 66-79页

作者： Yaxin TAO Xiaodi DAI Geert de.SCHUTTER Kim van TITTELBOOM de.artment of Structural Engineering and Building Materials Ghent UniversityGhent 9052Belgium

Robotic-based technologies such as automated spraying or extrusion-based 3-dimensional(3D)concrete printing can be used to build tunnel linings,aiming at reducing labor and mitigating the associated safety issues,especially in the high-geothermal ***-based 3D concrete printing(3DCP)has additional a.vantages over automated sprayings,such as improved surface quality and no ***,the effect of different temperatures on the adhesion performance of 3D-printed materials for tunnel linings has not been *** study de.eloped several alkali-activated slag mixtures with different activator modulus ratios to avoid the excessive use of Portland cement and enhance sustainability of 3D printable *** thermal responses of the mixtures at different temperatures of 20 and 40℃ were *** adhesion strength of the alkali-activated material was evaluated for both early and later ***,the structural evolution of the material exposed to different temperatures was *** was followed by microstructure *** indicate that elevated temperatures accelerate material reactions,resulting in improved early-age adhesion ***,higher temperatures contribute to the de.elopment of a de.ser microstructure and enhanced mechanical strength in the harde.ed stage,particularly in mixtures with higher silicate content.

关键词： alkali-activated material 3DCP tunnel lining high-geothermal environment adhesion

Influence of curing conditions on the shrinkage behavior of three-dimensional printed concrete formwork

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Frontiers of Structural and Civil Engineering 2024年第8期18卷 1225-1236页

作者： M.BEKAERT K.van TITTELBOOM G.de.SCHUTTER Magnel-vande.itte Laboratory for structural Engineering and Building Materials Department of Structural Engineering and Building MaterialsFaculty of Engineering and ArchitectureGhent UniversityGhent 60 B-9052Belgium

The use of three-dimensional(3D)printed concrete as formwork is becoming more wide.y applied within the ***,the technology is still not optimized and there are many reports of preliminary cracking during the curing of cast *** is believed to result from differential shrinkage between the printed and cast *** cracks(in the printed concrete or at the interface between the infill and printed concrete)form a preferential path for aggressive substances and can reduce the durability of the combined concrete *** ensure the de.ired service life of the structure,it is important that the differential shrinkage between cast and printed concrete is *** study investigated the effect of curing conditions on the differential shrinkage behavior of 3D and cast *** influence of prewetting of the dry-cured 3D printed formwork was also *** the experimental program,a vibrated and self-compacting concrete were used as cast *** 3D printed formwork was produced and combined with cast concrete to simulate a concrete *** formwork was cured for 1,7,or 28 d exposed to the air(relative humidity:60%or 95%)or submerged in *** length change of the combined elements was observed over 56 d after concrete casting and throughout the thickness of the *** show that increasing the curing period in dry conditions of the printed concrete leads to an expansion of the formwork on the first day after *** expansion leads to a non-uniform strain evolution throughout the curing period of the combined *** concrete formwork stored in wet conditions does not expand after the casting process but tends to show a de.reasing linear de.ormation within the whole elements.

关键词： 3D concrete printing formwork shrinkage curing

Sturge–Weber syndrome:an update for the pediatrician

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World Journal of Pediatrics 2024年第5期20卷 435-443页

作者： Emilie Dingenen Damien Segers Hannelore de.Maeseneer Dirk van Gysel Ghent University Faculty of Medicine and Health Sciences GhentBelgium de.artment of Pediatrics O.L.Vrouw Hospital AalstMoorselbaan 1649300AalstBelgium Interdisciplinary Unit of Pediatric de.matology Vrije Universiteit Brussel(VUB)Universitair Ziekenhuis Brussel(UZ Brussel)BrusselsBelgium

Sturge–Weber syndrome(SWS)is a rare congenital neurocutaneous disorde. characterized by the simultaneous presence of both cutaneous and extracutaneous capillary *** usually presents as a facial port-wine birthmark,with a varying presence of leptomeningeal capillary malformations and ocular vascular *** latter may lead to significant neurological and ocular morbidity such as epilepsy and *** is most often caused by a somatic mutation involving the G protein subunit alpha Q or G protein subunit alpha 11 gene causing various alterations in downstream signaling *** specifically conducted a comprehensive review focusing on the current knowledge of clinical practices,the latest pathophysiological insights,and the potential novel therapeutic avenues they *** sources A narrative,non-systematic review of the literature was conducted,combining expert opinion with a balanced review of the available literature.A search of PubMed,Google Scholar and Embase was conducted,using keywords“Sturge–Weber Syndrome”OR“SWS”,“Capillary malformations”,“G protein subunit alpha 11”OR“G protein subunit alpha Q”.Results One of the hallmark features of SWS is the presence of a port-wine birthmark at birth,and forehead involvement is most indicative for *** most common ocular manifestations of SWS are glaucoma and choroidal *** presents in either in infancy(0–3 years of age)or later in *** complications are common in SWS,occurring in about 70%–80%of patients,with seizures being the most common *** significantly impacts the quality of life for patients and their families,and requires a multidisciplinary approach for diagnosis and ***,no disease-modifying therapies exist,and treatment is mostly focused on symptoms or complications as they *** SWS remains a complex and heterogeneous *** research is neede. to optimize diagnostic and therapeutic strategies,and to transl

关键词： Capillary malformations G-protein Gq-G11 Port-wine birthmark Neurocutaneous disorde. Sturge-Weber syndrome

Clinical-based phenotypes in children with pediatric post-COVID-19 condition

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World Journal of Pediatrics 2024年第7期20卷 682-691页

作者： Lieke C.E.Noij Jelle M.Blankestijn Coen R.Lap Marlies a.van Houten Giske Biesbroek Anke-Hilse Maitland-van de. Zee Mahmoud I.Abde.-Aziz Johannes B.van Goudoever Mattijs W.Alsem Caroline L.H.Brackel Kim J.Oostrom Simone Hashimoto Suzanne W.J.Terheggen-Lagro de.artment of Pediatric Pulmonology and Allergy Amsterdam UMCLocation AMCEmma Children’s HospitalAmsterdam University Medical CenterRoom G2-222Meibergdreef 91105AZAmsterdamThe Netherlands de.artment of Pulmonary Medicine Amsterdam UMCAmsterdamThe Netherlands de.artment of Pediatrics Spaarne GasthuisHoofddorpThe Netherlands de.artment of Pediatrics Emma Children’s HospitalAmsterdam University Medical CenterAmsterdamThe Netherlands de.artment of Rehabilitation Medicine Amsterdam Movement SciencesMeibergdreef 9AmsterdamThe Netherlands de.artment of Paediatric Pulmonology Department of PaediatricsTergooi MCHilversumThe Netherlands de.artment of Child and Adolescent Psychiatry and Psychosocial Care Amsterdam UMCAmsterdam Reproduction and DevelopmentAmsterdamThe Netherlands

Background Pediatric post coronavirus disease 2019(COVID-19)condition(PPCC)is a heterogeneous syndrome,which can significantly affect the daily lives of *** study aimed to ide.tify clinically meaningful phenotypes in children with PPCC,to better characterize and treat this *** Participants were children with physician-diagnosed PPCC,referred to the acade.ic hospital Amsterdam UMC in the Netherlands between November 2021 and March *** factors and information on post-COVID symptoms,comorbidities,and impact on daily life were *** clusters were ide.tified using an unsupervised and unbiased approach for mixed data *** Analysis of 111 patients(aged 3–18 years)revealed three distinct clusters within *** 1(n=62,median age=15 years)predominantly consisted of girls(74.2%).These patients suffered relatively more from exercise intolerance,dyspnea,and smell *** 2(n=33,median age=13 years)contained patients with an even gende. distribution(51.5%girls).They suffered from relatively more sleep problems,memory loss,gastrointestinal symptoms,and *** 3(n=16,median age=11 years)had a higher proportion of boys(75.0%),suffered relatively more from fever,had significantly fewer symptoms(median of 5 symptoms compared to 8 and 10 for clusters 1 and 2 respectively),and experienced a lower impact on daily *** This study ide.tified three distinct clinical PPCC phenotypes,with variations in sex,age,symptom patterns,and impact on daily *** findings highlight the need for further research to unde.stand the potentially diverse unde.lying mechanisms contributing to post-COVID symptoms in children.

关键词： Adolescents Clusters Long COVID Pediatric Phenotypes Post-COVID syndrome

Editorial for Special Issue on Artificial Intelligence for Art

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Machine Intelligence Research 2024年第1期21卷 1-3页

作者： Luntian Mou Feng Gao Zijin Li Jiaying Liu Hongxun Yao Johan F.hoorn Beijing University of Technology China Peking University China Central Conservatory of Music China Harbin Institute of Technology China The Hong Kong Polytechnic University China

As an innovative engine for digital content generation,AI-generated content(AIGC)has drawn more and more attention from acade.ic fields as well as *** in the area of art creation,AI has de.onstrated its great potential and gained increasing *** are greatly impressed by AI painting,composing,writing,virtual hosting,fashion,and ***,AI is also becoming capable of unde.standing art,evaluating the aesthetic value of art,and protecting the copyright of art as *** has not only exhibited creativity to some extent,but also served as an enabling tool to discover the principles unde.neath creativity and imagination,which are traditional challenges for neuroscience,cognitive science,and *** all these promising features of AI for art,we still have to face the many challenges such as the explainability of generative mode.s and the copyright issues of AI art works.

关键词： gained becoming spite

A tribo-chemical view on astringency of plant-based food substances

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Friction 2024年第7期12卷 1392-1407页

作者： Samuel S.GAMANIEL Paloma S.DUEÑAS ROBLES Hans TROMP Els H.A.de.HOOG Sissi de.BEER Emile van de. HEIde Laboratory for Surface Technology and Tribology Faculty of Engineering TechnologyUniversity of TwenteEnschede 7522 LWthe Netherlands NIZO Food Research B.V. Ede6710 BAthe Netherlands de.artment of Molecules and Materials MESA+Institute for Nanotechnology University of TwenteEnschede 7500 AEthe Netherlands

Consumption of plant-based food products having high composition of polyphenols leads to the sensation of *** sliding oral surfaces,friction is an essential property during the oral perception of roughness and dryness which are attributes associated with *** factors including the chemical composition of interacting layers,structure and operation of interfaces have an effect on the astringency de.elopment *** manner of interactions occurring at oral interfaces suggest there is a system de.ende.ce of astringency and highlights the importance of adopting a tribosystems *** measurement techniques have shown an existing relationship between salivary protein-polyphenol interaction and an astringent ***,the tribo-chemistry involved in this multifaceted sensation remains largely unexplored in a comprehensive *** this review the unde.lying tribo-chemical processes useful in unde.standing the mechanism of astringency are highlighted and discussed conside.ing current techniques employed to investigate astringency *** of lubrication on oral surfaces owing to the tribo-chemical interactions involving saliva and astringent plant proteins requires subsequent de.ormations of oral tissues which are significant enough to induce strains at mechanoreceptor locations,leading to the sensation of *** is proposed that micro-scale contact mode.ling on the interaction of food particles/aggregates,boundary layers and oral surfaces shows potential in addressing the knowledge gap between tribo-chemical measurement techniques and panel tests,making it possible to attain a predictor for astringency.

关键词： oral lubrication astringency tribo-chemistry tribology

Urbanization does not increase“object curiosity”in vervet monkeys,but semi-urban individuals selectively explore food-related anthropogenic items

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Current Zoology 2024年第3期70卷 383-393页

作者： Lindsey Ellington Stephanie Mercier Alba Motes-Rodrigo Erica.van de.Waal Sofa Forss Behavioural&Physiological Ecology University of GroningenP.O.Box 111039700 CCGroningenThe Netherlands de.artment of Ecology and Evolution University of LausanneBiophore-CH-1015LausanneSwitzerland de.artment of Evolutionary Biology and Environmental Studies University of ZurichWinterthurerstrasse 190CH-8057ZurichSwitzerland School of Life Sciences University of KwaZulu-NatalPrivate Bag X01Scottsville3209South Africa

Urban environments expose animals to abundant anthropogenic materials and foods that facilitate foraging innovations in species with oppor-tunistic diets and high behavioral *** and exploration tende.cy are believed to be important behavioral traits for animals thriving in urban *** monkeys(Chlorocebus pygerythrus)are one of few primate species that have successfully adapted to urban environments,thus making them an ide.l species to study these *** a within-species cross-habitat approach,we compared neophilia and exploration of novel objects(jointly referred to as"object curiosity")between semi-urban,wild,and captive monkeys to shed light on the cognitive traits facilitating urban *** measure"object curiosity:"we exposed monkeys to various types of novel stimuli and compared their approaches and explorative *** results revealed differences in the number of approaches and explorative behavior toward novel stimuli between the habitat types *** vervet monkeys were significantly more explorative than both semi-urban and wild troops,sug-gesting that positive experiences with humans and lack of predation,rather than exposure to human materials per se,influence object *** habitats,juvenile males were the most explorative age-sex *** is likely due to males being the dispersing sex and juveniles being more motivated to learn about their ***,we found that items potentially associated with human food,elicited stronger explorative responses in semi-urban monkeys than non-food related objects,suggesting that their motivation to explore might be driven by"anthrophilia'that is,their experience of rewarding foraging on similar anthropogenic food *** conclude.that varying levels of exposure to humans,predation and pre-exposure to human food packaging explain variation in"object curiosity"in our sample of vervet monkeys.

关键词： animal urbanization neophilia novelty response object curiosity vervet monkeys

The shear strength of the interface between artificial rock and printed concrete at super-early ages

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Frontiers of Structural and Civil Engineering 2024年第1期18卷 51-65页

作者： Yong Yuan Xiaoyun Wang Jiao-Long Zhang Yaxin Tao Kim van Tittelboom Luc Taerwe Geert de.Schutter College of Civil Engineering Tongji UniversityShanghai 200092China State Key Laboratory of Disaster Reduction in Civil Engineering Tongji UniversityShanghai 200092China Belgium-China Joint Laboratory for Industrialized Construction Tongji UniversityShanghai 200092China Magnel-vande.itte Laboratory for Structural Engineering and Building Materials Ghent UniversityGhent 9052Belgium

3D concrete printing has the potential to replace shotcrete for construction of linings of tunnels in hard *** shear strength of the interface between rock and printed concrete is vital,especially at super-early ***,traditional methods for testing the shear strength of the interface,e.g.,the direct shear test,are time-consuming and result in a high variability for fast-harde.ing printed *** this paper,a new fast bond shear test is *** test can be completed in 1 min,with another 2 min for preparing the next *** influence of the matrix composition,the age of the printed matrices,and the interface roughness of the artificial rock substrate on the shear strength of the interface was experimentally *** tests were conducted at the age of the matrices at the 1st,the 4th,the 8th,the 16th,the 32nd,and the 64th min after its final setting.A dimensionless formula was established to calculate the shear strength,accounting for the age of the printed matrices,the interface roughness,and the shear failure *** was validated by comparing the calculated results and the experimental results of one group of samples.

关键词： rock tunnel printed concrete interface fast bond shear test shear strength

Nonsteroidal anti-inflammatory drugs before endoscopic ultrasound guide. tissue acquisition to reduce the incide.ce of post procedural pancreatitis

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World Journal of Gastroenterology 2024年第8期30卷 811-816页

作者： Mike de.Jong Foke van de.ft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema Marco Bruno de.artment of Gastroenterology and Hepatology Radboud University Medical CenterNijmegen 6525 GANetherlands de.artment of Gastroenterology and Hepatology Erasmus University Medical CenterRotterdam 3015 GDNetherlands

Endoscopic ultrasound(EUS)with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and auto-immune pancreatitis or to analyze cyst *** most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis,which is likely induced by the same pathophysiological mechanisms as after en-doscopic retrograde.cholangiopancreatography(ERCP).According to the current European Society of Gastrointestinal Endoscopy guide.ine,nonsteroidal anti-inflammatory drugs are administered prior to ERCP as a scientifically proven treatment to reduce post-ERCP pancreatitis incide.ce rate.A single suppository of diclofenac or indomethacin prior to EUS guide. tissue acquisition(TA)is harm-less in healthy *** it is associated with low costs and,most important,may prevent a dreadsome complication,we strongly recommend the adminis-tration of 100 mg diclofenac rectally prior to *** will explain this recom-mendation in more de.ail in this review as well as the risk and pathophysiology of post-EUS TA pancreatitis.

关键词： Pancreatitis Endoscopic ultrasound Tissue acquisition Nonsteroidal antiinflammatory drugs Pancreatic cancer

Ide.tific tion of quantitative trait loci and associated candidate genes for pregnancy success in Angus–Brahman crossbred heifers

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Journal of Animal Science and Biotechnology 2024年第1期15卷 162-170页

作者： Quinn A.hoorn Gabriel A.Zayas Eduardo E.Rodriguez Laura M.Jensen Raluca G.Mateescu Peter J.Hansen de.artment of Animal Sciences Donald Henry Barron Reproductive and Perinatal Biology Research Programand the Genetics InstituteUniversity of FloridaGainesvilleFLUSA School of Applied Systems Biology La Trobe UniversityBundooraVIC 3083Australia

Background In beef cattle, more than 50% of the energy input to produce a unit of beef is consumed by the female that produced the calf. de.elopment of genomic tools to ide.tify females with high genetic merit for reproductive function could increase the profitability and sustainability of beef *** Genome-wide.association studies(GWAS) were performed using a single-step genomic best linear unbiased prediction approach on pregnancy outcome traits from a population of Angus–Brahman crossbred heifers. Furthermore, a validation GWAS was performed using data from another farm. Heifers were genotyped with the Bovine GGP F250 array that contains 221,077 SNPs. In the discovery population, heifers were bred in winter breeding seasons involving a single round of timed artificial insemination(AI) followed by natural mating for 3 months. Two phenotypes were analyzed: pregnancy outcome to first-service AI(PAI;n = 1,481) and pregnancy status at the end of the breeding season(PEBS;n = 1,725). The heritability was estimated as 0.149 and 0.122 for PAI and PEBS, respectively. In the PAI mode., one quantitative trait locus(QTL), located between 52.3 and 52.5 Mb on BTA7, explained about 3% of the genetic variation, in a region containing a cluster of γ-protocadherin genes and SLC25A2. Other QTLs explaining between 0.5% and 1% of the genetic variation were found on BTA12 and 25. In the PEBS mode., a large QTL on BTA7 was synonymous with the QTL for PAI, with minor QTLs located on BTA5, 9, 10, 11, 19, and 20. The validation population for pregnancy status at the end of the breeding season were Angus–Brahman crossbred heifers bred by natural mating. In concordance with the discovery population, the large QTL on BTA7 and QTLs on BTA10 and 12 were *** In summary, QTLs and candidate SNPs ide.tified were associated with pregnancy outcomes in beef heifers, including a large QTL associated with a group of protocadherin genes. Confirmation of these associations

关键词： Beef cattle Fertility GWAS QTL