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Expanding the liver donor pool worldwide with hepatitis C infected livers, is it the time?

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World Journal of Transplantation 2024年第2期14卷 13-27页

作者： Mai hashem Mohammed A Medhat Doaa Abdeltawab Nahed A Makhlouf Fellow of Tropical Medicine and Gastroenterology Assiut University HospitalAssiut 71515Egypt Department of Tropical Medicine and Gastroenterology Faculty of MedicineAssiut UniversityAssiut 71515Egypt Department of Tropical Medicine and Gastroenterology Al-Rajhi Liver HospitalAssiut UniversityAssiut 71515Egypt

Liver transplantation(LT)provides a life-saving option for cirrhotic patients with complications and hepatocellular *** the increasing number of liver transplants performed each year,the number of LT candidates on the waitlist remains unchanged due to an imbalance between donor organ supply and the demand which increases the waitlist time and *** donor liver transplant had a great role in increasing the donor pool and shortened waitlist time for LT ***,further strategies can be implemented to increase the pool of potential donors in deceased donor LT,such as reducing the rate of organ *** hepatitis C virus(HCV)seropositive liver grafts is one of the expanded donor organ criteria.A yearly increase of hundreds of transplants is anticipated as a result of maximizing the utilization of HCV-positive organs for HCV-negative ***-acting antiviral therapy's efficacy has revolutionized the treatment of HCV infection and the use of HCV-seropositive donors in *** American society of Transplantation advises against performing transplants from HCV-infected liver donors(D+)into HCV-negative recipient(R-)unless under Institutional Review Board-approved study rules and with full informed consent of the knowledge gaps associated with such *** selection of patients to be transplanted with HCV-infected grafts and confirming their access to direct-acting antivirals if needed is *** and international consensuses are needed to regulate this process to ensure the maximum benefit and the least adverse events.

关键词： Donor pool Hepatitis C-viremic organs Non-viremic organs Direct acting antivirals Hepatitis C virus treated Liver transplantation

Vanillylacetone attenuates cadmium chloride-induced hippocampal damage and memory loss through upregulation of nuclear factor erythroid 2-related factor 2 gene and protein expression

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Neural Regeneration Research 2024年第12期19卷 2750-2759页

作者： Fahaid H.A.L-hashem salah O.Bashir Amal F.Dawood Moutasem s.Aboonq Ismaeel Bin-Jaliah Abdulaiziz M.Al-Garni Mohamed D.Morsy Department of Physiology College of MedicineKing Khalid UniversityAbhaSaudi Arabia Department of Basic Medical sciences College of MedicinePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia Department of Physiology College of MedicineTaibah UniversityAl-Madinah Al-MunawwarahSaudi Arabia Department of Medicine College of MedicineKing Khalid UniversityAbhaSaudi Arabia

Memory loss and dementia are major public health concerns with a substantial economic *** stress has been shown to play a crucial role in the pathophysiology of hippocampal damage-induced memory *** investigate whether the antioxidant and anti-inflammatory compound vanillyla cetone(zingerone) can protect against hippocampal damage and memory loss induced by cadmium chloride(CdCl_(2)) administration in rats,we explo red the potential involvement of the nuclear factor erythroid 2-related factor 2(Nrf2) signaling pathway,which is known to modulate oxidative stress and *** healt hy male Wistar rats were divided into five groups:vehicle-treated(control),vanillylacetone,CdCl_(2),vanillylacetone+ CdCl_(2),vanillylacetone+ CdCl_(2)+ brusatol(a selective pharmacological N rf2inhibitor) *** effectively attenuated CdCl_(2)-induced damage in the dental gyrus of the hippocampus and improved the memory function assessed by the Morris Water Maze ***,vanillylacetone markedly decreased the hippocampal tissue levels of inflammatory biomarkers(interleukin-6,tumor necrosis factor-α,intracellular cell adhesive molecules) and apoptosis biomarkers(Bax and cleaved caspase-3).The control and CdCl_(2)-treated groups treated with va nillylacetone showed reduced generation of reactive oxygen species,decreased malondialdehyde levels,and increased superoxide dismutase and glutathione activities,along with significant elevation of nuclear Nrf2 mRNA and protein expression in hippocampal *** the protective effects of vanillylacetone we re substantially blocked by the co-administration of brusatol(a selective N rf2 inhibitor).Va nillylacetone mitigated hippocampal damage and memory loss induced by CdCl_(2),at least in part, by activating the nuclear transcription factor ***,vanillylacetone exerted its potent antioxidant and antiinflammatory actions.

关键词： hippocampus neuroprotective Nrf2 gene oxidative stress vanillylacetone

Exploring dielectric phenomena in sulflower-like nanostructures via Monte Carlo technique

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Communications in Theoretical Physics 2024年第4期76卷 188-198页

作者： N saber Z Fadil Hussein sabbah A Mhirech B Kabouchi L Bahmad Chaitany Jayprakash Raorane siva sankar sana Hassan Fouad Mohamed hashem Laboratory of Condensed Matter and Interdisciplinary sciences(LaMCscI) Research Unit Labelled CNRSTURL-CNRST-17.Faculty of SciencesPO Box 1014Mohammed Ⅴ University in RabatMorocco College of Engineering and Technology American University of the Middle EastEgaila 54200Kuwait school of Chemical Engineering Yeungnam UniversityGyeongsan38541Republic of Korea Applied Medical science Department Community CollegeKing Saud UniversityPO Box 11433Riyadh Saudi Arabia Department of Dental Health College of Applied Medical SciencesKing Saud UniversityPO Box 12372RiyadhSaudi Arabia

This research focuses on the electric behavior of a mixed ferrielectric sulflower-like *** structure includes a core with spin s_(i)^(Z)-1 atoms and a shell with spin σ_(j)^(Z)-5/2 *** Blume–Capel model and the Monte Carlo technique(MCt)with the Metropolis algorithm are *** are established for absolute zero,investigating stable spin configurations correlated with various physical *** MCt method explores phase transition behavior and electric hysteresis cycles under different physical parameters.

关键词： sulfower-like nanostructure dielectric characteristics Monte Carlo technique phase transition phase diagrams electric hysteresis

spatial correlation of pit and mound topography with canopy gaps in a virgin mixed beech forest, northern Iran

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Journal of Forestry Research 2019年第1期30卷 295-303页

作者： hashem Habashi Faculty of Forest sciences Gorgon University of Agricultural Sciences and Natural Resources

In a reserved forest parcel in a virgin eastern Hyrcanian mixed beech forest,80 ha was surveyed to determine the pit and mound topography,canopy gaps and dead *** aim was to investigate the spatial patterns and correlation of pit and mound features with canopy ***-five canopy gaps and 61 pit and mound features were *** univariate first order nearest neighbor(R_(CE))and bivariate second order test(Ripley’s K)statistic were applied.R_(CE) statistics highlighted a general aggregation pattern for canopy gaps and pits and mounds,while pits and mounds alone were more *** between canopy gaps were 130 m average,whereas distances between pit and mound features and dead trees were 60 and 78 m,*** positive correlation of canopy gaps with pits and mounds were observed with all *** result of spatial correlations between canopy gaps with pits and mounds confirmed that windthrows cause micro successions in fallen tree ecosystem-scale correlated with gap phase dynamics in the forest community-scale.

关键词： Pit and mound Canopy gap Mixed beech spatial pattern spatial correlation

Control of purity and entanglement for two spatially two-separated qubits via phase damping

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Chinese Physics B 2012年第10期21卷 115-121页

作者： A.s.F.Obada H.A.Hessian A.B.A.Mohamed M.hashem Faculty of science Al-Azhar UniversityNasr CityCairoEgypt Faculty of science Assiut UniversityAssiutEgypt Faculty of science Al-Baha UniversityAl-BahaSaudi Arabia Al-Aflaj Community College Salman Bin Abdulaziz University Al-AflajSaudi Arabia

Control of purity and entanglement of two two-qubits dispersively coupled to a field with a reservoir are *** the qubits are entangled,while the field is either in a coherent state or a statistical mixture of two coherent *** an alternative entanglement measure we calculate the negativity of the eigenvalues of the partially transposed density matrix.A measure related to the mutual entropy,namely the index of entropy,is employed to measure the *** results agree well with the *** is found that the entanglement and purity have strong sensitivity to phase *** asymptotic behaviour of the states of the field,the two two-qubits,and the total system fall into mixed states.

关键词： entanglement phase damping purity separated qubits

Evaluation of Al and some of Its Alloys as Anode Materials vs γ-MnO_2 as Cathode Material and Ore Produced γ-MnO_2 vs Zn Anode in KOH solution

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Journal of Materials science & Technology 2006年第1期22卷 25-30页

作者： A.M.A.hashem Kh.s.Abou-El-sherbini s.Zein El Abedin H.Abbas Inorganic Chemistry Department National Research CentreBehoes StreetDokkiCairoEgypt Physical Chemistry Department National Research CentreBehoes StreetDokkiCairoEgypt

In this study electrochemical performance of Al and some of its alloys （Al-Zn, Al-rvlg and Al-rvln） anodes vs MnO2 cathode were carried out in alkaline solution. The results show that the Al-Zn alloy anode has the best cell capacity among the other alloys. Cell capacity values go in the order Al-Zn〉Al-Mg〉Al〉Al-Mn. This result is probably related to the nature of passive films formed on the surface of the alloys which examined by scanning electron microscopy （sEM）. sEM morphologies of Al and its alloys showed coarse grains of passive films formed on the surface of these anode materials while Al-Mn morphology shows a needle-like structure. Electrolytic manganese dioxide （EMD） produced by electrodepositing on platinum anode from liquor resulting from reduction of low grade pyrolusite ore （β-MnO2） by sulfur slag was characterized as cathode in alkaline Zn-MnO2 batteries. Ore produced sample （EMD1） was performed well in comparison with EMD standard （EMD2）（commercial battery grade electrolytic manganese dioxide, TOsOH-Hellas GH-s）. sEM morphology of Zn anode after cell reaction was carried out and showed that Zn anode has fine grains of passive film on its surface.

关键词： Electrolytic MnO2 Zn Al Alkaline batteries

Assessing effects of deficit irrigation techniques on water productivity of tomato for subsurface drip irrigation system

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International Journal of Agricultural and Biological Engineering 2018年第4期11卷 156-167页

作者： Mahmoud s hashem Tarek Zin El-Abedin Hussein M Al-Ghobari Agricultural Engineering Department College of Food and Agriculture SciencesKing Saud UniversityRiyadh 11451Saudi Arabia Agricultural Engineering Research Institute(AEnRI) Agricultural Research CenterGizaEgypt Agricultural Engineering Department College of AgricultureAlexandria UniversityAlexandriaEgypt

Water resources are subjected to ever-increasing supply constraints due to extensive agricultural water demand for irrigated ***,water-saving irrigation strategies need to be *** present study was conducted to explore the possibilities of using regulated deficit irrigation(RDI)and partial root zone drying irrigation(PRD)methods as water-saving irrigation techniques for subsurface *** objective of this study are to assess the effects of RDI and PRD irrigation on the water productivity of vegetable crops(tomato)under ssD systems in arid climatic conditions,and to compare the responses of tomato crops to PRD,RDI,and FI under an ssD system in terms of productivity,crop quality,and the amount of water *** field experiment was conducted during the fall 2014-2015 and 2015-2016 seasons in an experimental field located on an educational farm owned by the Faculty of Food and Agriculture sciences Department,King saud University,Riyadh,Kingdom of saudi *** area of 102.7 m^(2)(13 m×7.9 m)was allocated for the experiment to manage three treatments:RDI,PRD,and full irrigation(FI).The RDI and PRD treatments received 70%of the irrigation water volume of *** was replicated three *** most important results indicated that the soil water content(sWC)for the RDI and PRD treatments was lower than that of the FI *** had the highest stomatal conductance values(gs),while PRD had the lowest stomatal conductance *** photosynthetic rate(A_(n))was lower under RDI and PRD compared to ***,there was no significant change in A_(n) between treatments for most readings taken during both time periods,which means that the water saving treatments(PRD and RDI)did not affect the net photosynthesis rate,thereby enhancing irrigation water use efficiency(IWUE)under DI *** water-saving irrigation techniques decreased transpiration rate(T)compared to the FI *** values of the abscisic acid(ABA)contents were higher

关键词： full irrigation(FI) regulated deficit irrigation(RDI) partial root zone drying(PRD) irrigation water use efficiency(IWUE)

Monte Carlo Analytic Hierarchy Process (MAHP) approach to selection of optimum mining method

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International Journal of Mining science and Technology 2013年第4期23卷 561-566页

作者： Ataei Mohammad shahsavany hashem Mikaeil Reza Faculty of Mining Petroleum and Geophysics Engineering Shahrood University of Technology Faculty of Mining Engineering Kordestan University Faculty of Mining Engineering Uromia University of Technology

One of the most critical and complicated steps in mine design is a selection of suitable mining method based upon geological,geotechnical,geographical,safety and economical *** aim of this study is developing a Monte Carlo simulation to selection the optimum mining method by using effective and major criteria and at the same time,taking subjective judgments of decision makers into *** approach is based on the combination of Monte Carlo simulation with conventional Analytic Hierarchy Process(AHP).Monte Carlo simulation is used to determine the confdence level of each alternative’s score,is calculated by AHP,with the respect to the variance of decision makers’*** proposed method is applied for Jajarm Bauxite Mine in Iran and eventually the most appropriate mining methods for this mine are ranked.

关键词： Multi-criteria decision making AHP Monte Carlo simulation Mining method selection

Effect of the Mesh Transparency on the Electrical Characteristics of DC Pseudo Discharge

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Plasma science and Technology 2015年第6期17卷 481-487页

作者： M.A.Abd AL-HALIM A.ABU-hashem D.I.MOUBARAK Physics Department Faculty of ScienceBenha University Basic science Department Thebes High Institute of Engineering

A DC pseudo discharge for air has been studied. Air pressure is used in the range between 0.7 Torr and 12 Torr. The breakdown occurs between a plane cathode and a mesh anode at transparencies of 19%, 46%, and 65%. The current-voltage characteristic curves of the discharge, which are measured at different pressures, distances, and mesh transparences, take effect in the region of abnormal glow. The discharge voltage decreases as the air pressure increases, while more voltage is needed to maintain the discharge when either the mesh transparency or the inter- electrode distance is increased. An increment of mesh transparency causes high negative potential behind the mesh due to the high concentration of electrons, which accumulate and collide with neutral atoms. Paschen curves deviate from the expected regular one. The left side of Paschen curves appears at inter-electrode distance of 1 mm, whereas the right side appears at inter-electrode distance of 5 mm. The intermediate region is observed only at 3 mm distance between the two electrodes. For the transparency range used in this work, it is found that the decrement of the breakdown voltage, on the right side, depends on the mesh transparency. For different electrode separations, the measured Paschen curves are coincident and deviate from the standard ones of Paschen＇s law.

关键词： pseudo discharge mesh transparency Paschen curves