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Journal of Advanced Dielectrics 2019年第6期9卷 10-22页

作者： M.Saleem Shivani Chouhan a.mishra Materials Science Laboratory School of Physics Vigyan BhawanDevi Ahilya University Khandwa Road CampusIndore 452001India

The preparation of La_(0.9)Na_(0.1)CrO_(3)(LNCO),Ni_(0.5)Cu_(0.5)Fe_(2)O_(4)(NCFO)and their composites of the type e1xT La_(0.9)Na_(0.1)CrO_(3)(LNCO)t(x)Ni_(0.5)Cu_(0.5)Fe_(2)O_(4)(NCFO)ex?0.25,0.50T through solid state route is *** X-ray diffraction data analysis,the parent La_(0.9)Na_(0.1)CrO_(3)was found to crystallize in orthorhombic structure(Pnma)while Ni_(0.5)Cu_(0.5)Fe_(2)O_(4)has crystallized into the cubic structure(Fd3m)further verified via Retvield *** morphology and compositional studies were carried out using field emission scanning electron microscopy(FESEM)and energy dispersive analysis of X-rays(EDAX),*** structure was confirmed via Raman characterization for the prepared *** sample formation was further verified through Fourier transform Infra-Red(FTIR)*** dielectric studies reveal the La_(0.9)Na_(0.1)CrO_(3)e13*10^(4)T and Ni_(0.5)Cu_(0.5)Fe_(2)O_(4)e1.83*10^(4)T exhibit high dielectric ***,their composites show abrupt drop in dielectric *** electric modulus study confirmed that the samples exhibit non-Debye character with spread of relaxation time constants.

关键词： Structure Retvield refinement morphology dielectric properties

Low dielectric constant and signature of ferroelectric nature in transition metal(Co,Ni,Cu)-doped Mg_(0.5)Zn_(0.5)Al_(2)O_(4)aluminates

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Journal of Advanced Dielectrics 2019年第4期9卷 63-70页

作者： M.Saleem M.Padole a.mishra Materials Science Laboratory School of Physics Vigyan BhawanDevi Ahilya University Khandwa Road CampusIndore 452001India

This paper throws light on the preparation of transition metal-doped Mg_(0.5)Zn_(0.5)Al_(2)O_(4)(x=0,0.05 and TM=Co,Ni,Cu)aluminates via solid-state reaction *** X-ray diffraction characterization analysis confirmed that all the samples have crystallized into the psuedocubic phase having space group Fd3m and were single *** incorporation of transition metals ***^(2+),Ni^(2+),Cu^(2+)in the Mg_(0.5)Zn_(0.5)Al_(2)O_(4)matrix does not result in the appearance of new peaks or any considerable shift in diffraction peaks within the limits of XRD *** infers homogeneous dispersion of dopants at the Mg-site which is attributed to nearly same ionic radii of the dopants to that of Mg-site in Mg 0:5 Zn0:5 Al 2 O *** structure,bonding nature and hence the spinel formation were verified through Raman scattering *** compositional verification was carried out via energy dispersive analysis of X-rays(EDAX).The surface morphology and hence the microstructural studies were carried out using field emission scanning electron microscopy(FESEM).The synthesized Mg_(0.5)Zn_(0.5)Al_(2)O_(4)(x=0,0.05 and TM=Co,Ni,Cu)aluminate samples were tested for polarization studies keeping their insulating nature into consideration and they displayed a sign of well-behaved P-E loop.

关键词： Nanoparticles structure morphology polarization

Pulmonary delivery of liposomal dry powder inhaler formulation for effective treatment of idiopathic pulmonary fibrosis

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Asian Journal of Pharmaceutical Sciences 2018年第1期13卷 91-100页

作者： S.Chennakesavulu a.mishra A.Sudheer C.Sowmya C.Suryaprakash Reddy E.Bhargav Pharmacy Department NDDS Laboratory Donors Plaza Faculty of Technology and Engineering The Maharaja Sayajirao University of Baroda Pharmacology Department Faculty of Technology and Engineering The Maharaja Sayajirao University of Baroda Center for Pharmaceutical Research Pharmaceutics Department Raghavendra Institute of Pharmaceutical Education and Research

Dry powder inhaler Liposomes were prepared to investigate the effectiveness of pulmonary delivery of Colchicine and Budesonide for Idiopathic Pulmonary fibrosis. Budesonide(BUD) and Colchicine(COL) liposomes were prepared by thin layer film hydration method(TFH) using 1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium(DPPG), Hydrogenated Soyaphosphotidylcholine(HSPC), Soyaphosphatidylcholine(SPC), cholesterol(CHOL) and drug in different weight ratios. The optimum lipid composition for BUD(74.22 ± 0.97%) was DPPG:HSPC: CHOL(4:5:1) and for COL(50.94 ± 2.04%) was DPPG: SPC: CHOL(3:6:1). These compositions retained drug for a longer period of time so selected for further study. Liposomes were found to be spherical in shape with mean size below 100 nm. Liposomes lyophilized using Mannitol as carrier and cryoprotectant showed high entrapment efficiency(97.89-98.6%). The powder was dispersed through an Andersen cascade impactor to evaluate the performance of the aerosolized powder. It was found that prepared liposomal dry powder inhaler(DPIs) sustained the drug release up to 24 hours. Optimized Budesonide DPI Formulation B2(86.53 ± 1.9%), Colchicine DPI Formulation C2(90.54 ± 2.3 %) and BUD and COL DPI Combination M2(89.91 ± 1.8%, 91.23 ± 1.9%). Histopathological results, measurements of lung hydroxyproline content, Myeloperoxidase activity indicated that liposomal drypowder inhaler administration attenuates lung fibrosis induced by bleomycin. Long term stability studies indicated that lyophilised BUD and COL liposomes were stable for 6 months at(25 °C± 2 °C, 60% ± 5% RH) and refrigerated conditions(2-8 °C). These results supported that combination of budesonide and colchicine liposomal dry powder inhaler pulmonary drug delivery for treatment of idiopathic Pulmonary Fibrosis exhibits prolonged drug retention at targeted site and reduces the systemic exposure.

关键词： Idiopathic Pulmonary fibrosis Budesonide Colchicine Liposomal dry powder inhaler Pulmonary drug delivery

Dielectric and ferroelectric properties of CoCr_(2)O_(4)nanoceramics

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Journal of Advanced Dielectrics 2019年第3期9卷 1-7页

作者： Pankaj Choudhar P.Saxena A.Yadav V.N.Rai a.mishra Materials Science Laboratory School of Physics Vigyan BhawanDevi Ahilya University Khandwa Road CampusIndore 452001India Department of Physics Medi-Caps University PigdamberIndore 453331India

CoCr_(2)O_(4)nanoceramics are prepared by sol-gel auto combustion *** X-ray diffraction analysis affirms the singlephasepristine cubic structure with space group ***-Scherrer method estimates the crystallite size of main intense peak tobe~27:15 *** bands obtained in infrared spectra at 448 and 599 cm^(-1)are due to metal-oxygen stretching bond presentat tetrahedral and octahedral *** parameters decrease as frequency increases from 103 to 106 Hz that can be interpretedby Maxwell-Wagner-type interfacial *** impedance spectra(Nyquist plot)reveal arc like behavior,which ismainly due to intergrain(grain boundary)resistance that also exhibits conducting nature of the *** ferroelectricityis mainly associated with the partial reversal of the *** current behavior follows the Ohmic and Child square *** conduction process was interpreted by space-charge limited current(SCLC)*** current behaviorobserved in cobalt chromite nanoceramics is mainly attributed to the oxygen vacancies.

关键词： CoCr_(2)O_(4)nanoceramics synchrotron X-ray diffraction dielectric spectroscopy electric polarization leakage currentbehavior

Spectroscopic analysis and temperature-dependent dielectric properties of bulk Ni-Zn ceramics

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Journal of Advanced Dielectrics 2019年第2期9卷 21-32页

作者： Anand Yadav Pankaj Choudhary P.Saxena V.N.Rai a.mishra Materials Science Laboratory School of Physics Vigyan BhawanDevi Ahilya University Khandwa Road CampusIndore 452001India Department of Physics Medi-Caps University PigdamberRau 453331India

In the present work,series of Zn ion-doped Ni_(1-x)Zn_(x)Fe_(2)O_(4)(0:0≤x≤0.5)ceramics were prepared by the double sintered solidstate reaction route to find out the influence of Zn2t ions on the crystal structure,lattice structure and dielectric behavior of parent NiFe_(2)O_(4).X-ray diffraction(XRD)study favors that all the prepared compounds belong to the cubic spinel *** parameters found to have increasing value with increased Zn^(2+)ion *** Raman scattering measurement discerns optical-active modes with blue shift as the doping *** dielectric constant(ε′)and dielectric tangent loss(tanδ)decrease with an increase in frequency and at higher frequency,both become *** parameters observe nonlinear behavior with increasing Zn^(2+)ion *** temperature dielectric constant of 10%Zn ion-doped NiFe_(2)O_(4)[Ni_(0.9)Zn_(0.1)Fe_(2)O_(4)]is much higher as compared to other prepared *** room temperature ac conductivity is found to increase with increase in frequency and temperature-dependent ac conductivity increases with increase in temperature.

关键词： Ni-Zn ferrite X-ray diffraction Rietveld refinement Raman spectroscopy dielectric measurements.

Effect of in ovo feeding of xylobiose and xylotriose on plasma immunoglobulin, cecal metabolites production, microbial ecology, and metabolic pathways in broiler chickens

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1578-1589页

作者： Razib Das Pravin mishra Birendra.mishra Rajesh Jha Department of Human Nutrition Food and Animal SciencesCollege of Tropical Agriculture and Human ResourcesUniversity of Hawaii at ManoaHonoluluHI 96822USA

Background Dietary supplementation of xylooligosac charides(XOS) has been found to influence gut health by manipulating cecal microbiota and producing microbe-origin *** no study investigated and compared the effect of in ovo feeding of xylobiose(XOS2) and xy lotriose(XOS3) in *** study investigated the effect of in ovo feeding of these XOS compounds on post-hatch gut health parameters in chickens.A total of 144 fertilized chicken eggs were divided into three groups:a) non-injected control(CON),b) XOS2,and c) *** the 17^(th) embryonic day,the eggs of the XOS2 and XOS3 groups were injected with 3 mg of XOS2 and XOS3 diluted in 0.5 mL of 0.85% normal saline through the amniotic *** hatching,the chicks were raised for 21 *** was collected on d 14 to measure plasma *** digests were collected for measuring short-chain fatty acids(SCFA) on d 14 and 21,and for microbial ecology and microbial metabolic pathway analyses on d 7 and *** The results were considered significantly different at P<*** quantified plasma IgA and IgG on d 14chickens,revealing no differences among the *** chromatography results showed no significant differences in the concentrations of cecal SCFAs on d 14 but significant differences on d ***;the SCFA concentrations were lower in the XOS3 than in the CON group on d *** cecal metagenomics data showed that the abundance of the family Clostridiaceae significantly decreased on d 7,and the abundance of the family Oscillospiraceae increased on d 21 in the XOS2 compared to the *** was a reduction in the relative abundance of genus Clostridium sense stricto 1 in the XOS2 compared to the CON on d 7 and the genus Ruminococcus,torques in both XOS2 and XOS3 groups compared to the CON on d *** XOS2 and XOS3 groups reduced the genes for chondroitin sulfate degradation Ⅰ and L-histidine degradation Ⅰpathways,which contribute to improved gut health,respectivelyc in the micr

关键词： Broiler In ovo Metagenomics Prebiotic Xylooligosaccharides

Numerical analysis of moving train induced vibrations on tunnel,surrounding ground and structure

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Earthquake Engineering and Engineering Vibration 2024年第1期23卷 179-192页

作者： Swati Srivastav Sowmiya Chawla Swapnil mishra Department of Applied Geophysics Indian Institute of Technology(ISM)Dhanbad 826004India Department of Civil Engineering Indian Institute of Technology(ISM)Dhanbad 826004India Department of Mining Engineering Indian Institute of Technology(ISM)Dhanbad 826004India

This study is focused on the effect of vibration induced by moving trains in tunnels on the surrounding ground and structures.A three-dimensional finite element model is established for a one-track railway tunnel and an adjacent twelve-storey building frame by using commercial software Midas GTS-NX(2019)and Midas *** study considered the moving load effect of a complete train,which varies with space as well as with *** effect of factors such as train speed,overburden pressure on the tunnel and variation in soil properties are studied in the time *** a result,the variations in horizontal and vertical acceleration for two different sites,i.e.,the free ground surface(without structure)and the area containing the structure,are ***,the displacement pattern of the raft foundation is plotted for different train *** lower speeds,the heaving phenomenon is negligible,but as the speed increases,both the heaving and differential settlement increase in the *** study demonstrates that the effect of moving train vibrations should be considered in the design of new nearby structures and proper ground improvement should be considered for existing structures.

关键词： moving train load tunnels vibration effect finite element method(FEM) wave propagation

Multi-head neural networks for simulating particle breakage dynamics

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Theoretical & Applied Mechanics Letters 2024年第2期14卷 130-141页

作者： Abhishek Gupta Barada Kanta.mishra School of Mechanical Sciences Indian Institute of Technology(IIT)GoaPonda 403401India School of Chemical and Materials Science Indian Institute of Technology(IIT)GoaPonda 403401India

The breakage of brittle particulate materials into smaller particles under compressive or impact loads can be modelled as an instantiation of the population balance integro-differential *** this paper,the emerging computational science paradigm of physics-informed neural networks is studied for the first time for solving both linear and nonlinear variants of the governing *** conventional methods,the proposed neural network provides rapid simulations of arbitrarily high resolution in particle size,predicting values on arbitrarily fine grids without the need for model *** network is assigned a simple multi-head architecture tailored to uphold monotonicity of the modelled cumulative distribution function over particle *** method is theoretically analyzed and validated against analytical results before being applied to real-world data of a batch grinding *** agreement between laboratory data and numerical simulation encourages the use of physics-informed neural nets for optimal planning and control of industrial comminution processes.

关键词： Particle breakage dynamics Population balance equation Physics-informed neural networks

Embryonic thermal manipulation:a potential strategy to mitigate heat stress in broiler chickens for sustainable poultry production

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1347-1375页

作者： Sadid Al Amaz Birendra.mishra Department of Human Nutrition Food and Animal SciencesCollege of Tropical Agriculture and Human ResourcesUniversity of Hawaii at ManoaAgSci 2161955 East‑West RdHonoluluHI 96822USA

Due to high environmental temperatures and climate change, heat stress is a severe concern for poultry health and production, increasing the propensity for food insecurity. With climate change causing higher temperatures and erratic weather patterns in recent years, poultry are increasingly vulnerable to this environmental stressor. To mitigate heat stress, nutritional, genetic, and managerial strategies have been implemented with some success. However, these strategies did not adequately and sustainably reduce the heat stress. Therefore, it is crucial to take proactive measures to mitigate the effects of heat stress on poultry, ensuring optimal production and promoting poultry well-being. Embryonic thermal manipulation(TM) involves manipulating the embryonic environment's temperature to enhance broilers' thermotolerance and growth performance. One of the most significant benefits of this approach is its cost-effectiveness and saving time associated with traditional management practices. Given its numerous advantages, embryonic TM is a promising strategy for enhancing broiler production and profitability in the poultry industry. TM increases the standard incubation temperature in the mid or late embryonic stage to induce epigenetic thermal adaption and embryonic metabolism. Therefore, this review aims to summarize the available literature and scientific evidence of the beneficial effect of pre-hatch thermal manipulation on broiler health and performance.

关键词： Broiler Embryo Epigenetics Global warming Thermoregulation

Relaxor ferroelectric behavior of BaBi_(4)Ti_(4)O_(15) aurivillius ceramic

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Journal of Advanced Dielectrics 2013年第2期3卷 52-58页

作者： T.Badapanda R.K.Harichandan a.mishra S.Anwar Department of Physics C.V.Raman College of Engineering BhubaneswarOdisha 752054India Department of Physics Centurion University of Technology&Management BhubaneswarOdisha 751020India Colloids&Materials Chemistry Institute of Minerals and Materials Technology BhubaneswarOdisha 751013India

Aurivillius type compound BaBi_(4)Ti_(4)O_(15)(BBT)ceramic was prepared by solid state reaction route and its electrical properties were studied.X-ray diffraction(XRD)pattern showed orthorhombic structure with space group A21am confirming it to be an m=4 member of the Aurivillius *** scanning electron microscope of the sintered pellet showed a plate-like morphology of grains which is a characteristic feature of the Aurivillius *** temperature and frequency dependence dielectric study showed a shifting of transition temperature with frequency indicating relaxor type behavior in the *** diffuseness parameter(γ)established the relaxor nature and it was attributed to the A-site cationic *** dielectric relaxation obeyed the VogelFulcher(VF)relation and various parameters like activation energy for relaxation,freezing temperature,relaxation frequency were determined after nonlinear curve *** temperature dependence of dielectric constant at temperatures much higher and lower than Tm was analyzed by two exponential functions,which gives an idea about the production of polar clusters at high temperature and the distribution of freezing temperatures at lower *** other associated parameters were calculated by nonlinear curve fitting and their significance has been explained.

关键词： Aurivillius compound diffuse phase transition relaxor ferroelectric P-E loop