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Surface geochemical data evaluation and integration with geophysical observations for hydrocarbon prospecting,Tapti graben,Deccan Syneclise,India

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Geoscience Frontiers 2014年第3期5卷 419-428页

作者： T.Satish Kumar a.m.dayal V.Sudarshan Centre of Excellence for Energy Studies Oil India LtdGuwahati 781022India National Geophysical Research Institute(CSIR) Hyderabad 500006India Applied Geochemistry Department Osmania UniversityHyderabad 500006India

The Deccan Syneclise is considered to have significant hydrocarbon potential. However, significant hydrocarbon discoveries, particularly for mesozoic sequences, have not been established through conventional exploration due to the thick basalt cover over mesozoic sedimentary rocks. In this study, near-surface geochemical data are used to understand the petroleum system and also investigate type of source for hydrocarbons generation of the study area. Soil samples were collected from favorable areas identified by integrated geophysical studies. The compositional and isotopic signatures of adsorbed gaseous hydrocarbons （methane through butane） were used as surface indicators of pe- troleum micro-seepages. An analysis of 75 near-surface soil-gas samples was carried out for light hydrocarbons （C_1-C_4） and their carbon isotopes from the western part of Tapti graben, Deccan Syneclise, India. The geochemical results reveal sites or clusters of sites containing anomalously high concentrations of light hydrocarbon gases. High concentrations of adsorbed thermogenic methane （C1 518 ppb） and ethane plus higher hydrocarbons （∑C2＋ = 977 ppb） were observed. Statistical analysis shows that samples from 13% of the samples contain anomalously high concentrations of light hydrocarbons in the soil-gas constituents. This seepage suggests largest magnitude of soil gas anomalies might be generated/source from mesozoic sedimentary rocks, beneath Deccan Traps. The carbon isotopic composition of methane, ethane and propane ranges are from 22.5‰to -30.2‰ PDB, -18.0‰ to 27.1‰,, PDB and 16.9‰-32.1‰ PDB respectively, which are in thermogenic source. Surface soil sample represents the intersection of a migration conduit from the deep subsurface to the surface connected to sub-trappean mesozoic sedimentary rocks. Prominent hydrocarbon concentra- tions were associated with dykes, lineaments and presented on thinner basaltic cover in the study area, which probably acts as channel for the micro-seep

关键词： Adsorbed gas microseepage Light hydrocarbon Stable isotope Geophysical Deccan Syneclise

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Geochemical evidences of trace metal anomalies for finding hydrocarbon microseepage in the petroliferous regions of the Tatipaka and Pasarlapudi areas of Krishna Godavari Basin,India

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Petroleum Science 2013年第1期10卷 19-29页

作者： Rasheed m A Lakshmi m Rao P L S Kalpana m S dayal A m Patil D J microbiology Laboratory Petroleum Geochemistry Group National Geophysical Research Institute (Council of Scientific and Industrial Research)

The long-term seepage of hydrocarbons, either as macroseepage or microseepage, can set up near-surface oxidation reduction zones that favor the development of a diverse array of chemical and mineralogical changes. The bacterial oxidation of light hydrocarbons can directly or indirectly bring about significant changes in the values of pH and Eh of the surrounding environment, thereby also changing the stability fields of the different mineral species present in that environment. The paper reports the role of hydrocarbon microseepage in surface alterations of trace metal concentrations. In this study trace metal alterations were mapped that appear to be associated with hydrocarbon microseepages in the oil/ gas fields. A total of 50 soil samples were collected near oil and gas fields of the Tatipaka and Pasarlapudi areas of the Krishna Godavari Basin, Andhra Pradesh. The soil samples were collected from a depth of 2-2.5 m. The paper reports the chemical alterations associated with trace metals in soils that are related to hydrocarbon microseepages above some of the major oil and gas fields of this petroliferous region. Trace metals, such as scandium （Sc）, vanadium （V）, chromium （Cr）, cobalt （Co）, nickel （Ni）, copper （Cu）, zinc （Zn）, barium （Ba） and strontium （Sr）, in soil samples were analyzed using inductively coupled plasma- mass spectrometry （ICP-mS）. The concentrations of Sc （8 to 40 mg/kg）, V （197 to 489 mg/kg）, Cr （106 to 287 mg/kg）, Co （31 to 52 mg/kg）, Ni （65 to 110 mg/kg）, Cu （88 to 131 mg/kg）, Zn （88 to 471 mg/kg）, Ba （263 to 3,091 mg/kg） and Sr （119 to 218 mg/kg） were obtained. It was observed that the concentrations of trace elements were tremendously increased when they were compared with their normal concentrations in soils. The analysis of adsorbed soil gas showed the presence of high concentrations of YC2＋（C2H6, C3H8 and n-C4H10） ranging from 7 to 222 μg/kg respectively. Integrated studies of trace elements over adsorbed light gaseous hydrocarbons （2C2

关键词： Hydrocarbons microseepage trace metal alterations adsorbed soil gas Krishna Godavari Basin

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Torsion of spleen and portal hypertension: Pathophysiology and clinical implications

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World Journal of Hepatology 2021年第7期13卷 774-780页

作者： Ashish Kumar Jha Sameer Bhagwat Vishwa mohan dayal Arya Suchismita Department of Gastroenterology Indira Gandhi Institute of Medical SciencesPatna 800014India Department of Paediatric Hepatology Institute of Liver and Biliary SciencesDelhi 110070India

The displacement of spleen from its normal location to other places is known as wandering spleen(WS)and is a rare *** repeated torsion of WS is due to the presence of long pedicle and absence/laxity of anchoring ligaments.A WS is an extremely rare cause of left-sided portal hypertension(PHT)and severe gastric variceal ***-sided PHT usually occurs as a result of splenic vein occlusion caused by splenic torsion,extrinsic compression of the splenic pedicle by enlarged spleen,and splenic vein *** is a paucity of data on WSrelated PHT,and these data are mostly in the form of case *** this review,we have analyzed the data of 20 reported cases of WS-related *** mechanisms of pathogenesis,clinico-demographic profile,and clinical implications are described in this *** majority of patients were diagnosed in the second to third decade of life(mean age:26 years),with a strong female preponderance(m:F=1:9).Eleven of the 20 WS patients with left-sided PHT presented with abdominal pain and *** 6 of the 11 patients,varices were detected incidentally on preoperative imaging studies or discovered ***,pre-operative search for varices is required in patients with splenic torsion.

关键词： Wandering spleen Splenic torsion Left-sided portal hypertension Gastric variceal bleeding Splenectomy

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Effect of replenishment of vitamin D on survival in patients with decompensated liver cirrhosis:A prospective study

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World Journal of Gastrointestinal Pathophysiology 2017年第3期8卷 133-141页

作者： Ashish Kumar Jha Sharad Kumar Jha Amarendra Kumar Vishwa mohan dayal Sanjeev Kumar Jha Department of Gastroenterology Indira Gandhi Institute of Medical SciencesSheikhpuraPatna 800014India

To assess the vitamin D (VD) deficiency as a prognostic factor and effect of replenishment of VD on mortality in decompensated cirrhosis. mETHODSPatients with decompensated liver cirrhosis were screened for serum VD levels. A total of 101 VD deficient patients (mL) were randomly enrolled in two groups: Treatment group (n = 51) and control group (n = 50). Treatment group received VD treatment in the form of intramuscular cholecalciferol 300000 IU as loading dose and 800 IU/d oral as maintenance dose along with 1000 mg oral calcium supplementation. The VD level, clinical parameters and survival of both the groups were compared for 6-mo. RESULTSPrevalence of vitamin D deficiency (VDD) in decompensated CLD was 84.31%. The mean (SD) age of the patients in the treatment group (m:F: 40:11) and control group (m:F: 37:13) were 46.2 (± 14.93) years and 43.28 (± 12.53) years, respectively. Baseline mean (CI) VD (ng/mL) in control group and treatment group were 9.15 (8.35-9.94) and 9.65 (8.63-10.7), respectively. mean (CI) serum VD level (ng/mL) at 6-mo in control group and treatment group were 9.02 (6.88-11.17) and 29 (23-35), respectively. Over the period of time the VD, calcium and phosphorus level was improved in treatment group compared to control group. There was non-significant trend seen in greater survival (69% vs 64%; P > 0.05) and longer survival (155 d vs 141 d; P > 0.05) in treatment group compared to control group. VD level had no significant association with mortality (P > 0.05). In multivariate analysis, treatment with VD supplement was found significantly (P mo. CONCLUSIONVD deficiency is very common in patients of decompensated CLD. Replenishment of VD may improve survival in patients with decompensated liver cirrhosis.

关键词： Chronic liver diseases Vitamin D Vitamin D deficiency Decompensated liver cirrhosis Survival

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Design of a railway tunnel parallel to an existing tunnel

Design of a railway tunnel parallel to an existing tunnel

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Harmonising Rock Engineering and the Environment—12th ISRm International Congress on Rock mechanics

作者： R.K.Goel A.Swarup R.K.dayal V.Bhardwaj CImFR Regional Centre RoorkeeIndia

＜正＞mumbai Rail Vikas Corporation Limited has planned to construct 5th and 6th railway lines from Thane to *** the route,the rail line passes through various geological features like creeks,lineament,hills and flood creek *** of the varied topography,various structures like bridges,foot over bridges and tunnels are to be *** per the Geotechnical investigation report,two tunnels are planned on the route. The proposed new tunnel having length 165 m,width 12 m and height 8.5 m is to be driven parallel to the existing tunnel.

关键词： Site characterization Rock mass classification Numerical modeling Tunnelling Rock support

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Identification of HCV Inhibitors from a Cell-Based Sub-Genomic Replicon Screen

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Open Journal of medicinal Chemistry 2013年第1期3卷 16-25页

作者： David C. Pryde Thien-Duc Tran mark Gardner Chris Pickford Stephen m. Shaw mike Westby Tanya Parkinson Caroline Smith-Burchnell Rob Webster Satish dayal Anti-Infectives Research Unit Pfizer Global Research and Develoapment Sandwich UK Anti-Infectives Research Unit Pfizer Global Research and Development Sandwich UK Pharmacokinetics Dynamics and Metabolism Pfizer Global Research and Development Sandwich UK Worldwide medicinal Chemistry Pfizer Global Research and Development Sandwich UK

A high throughput screen of the Pfizer compound collection was carried out using a hepatitis C virus (HCV) genotype 1b subgenomic replicon cell line. Those confirmed hits that demonstrated broad spectrum activity without overt cytotoxicity were further evaluated, leading to the identification of a series of pyrrolopyridines with excellent antiviral activity in a fully infectious HCV cell-based assay and pharmacokinetic properties.

关键词： HCV Replicon Antiviral Cell-Based Screen

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马铃薯实生种子千粒重、块茎产量及其他形态特性的相关研究

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中国马铃薯 1988年第2期 117-119页

作者： T.R.dayal m.D.Upadhya S.N.Chaturvedi 金黎平

用马铃薯72个杂交组合和18亲本第一代（F1）实生苗的9种性状一年的数据计算了表现型的、基因型的和环境的简单相关系数。用12个母本系和6个父本测交种按品系×测交种的模式做了杂交。试验设计采取了随机区组,重复3次,在Kafri,Simla（印... 详细信息

用马铃薯72个杂交组合和18亲本第一代（F1）实生苗的9种性状一年的数据计算了表现型的、基因型的和环境的简单相关系数。用12个母本系和6个父本测交种按品系×测交种的模式做了杂交。试验设计采取了随机区组,重复3次,在Kafri,Simla（印度）于1979～1980年作物生长期进行。发现了实生种子千粒重与块茎总产量、主茎叶片数、单株茎数和收获指数的表现型的和基因型的正相关。试验结果指出,实生种子千粒重能用于对F1代实生苗的产量和其他性状的选择。

关键词：千粒重表现型总产量实生苗杂交组合亲本杂种组合块茎产量实生种子形态特性

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EXCEL与PARTNER支架单一植入治疗急性ST段抬高型心肌梗死长期临床应用的安全性和有效性研究

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实用医学杂志 2013年第11期29卷 1764-1767页

作者：王琳曲鹏娄大元牛楠王虹艳袁大军丁彦春王纪文 Aswinee Kumar Karooa m.Fazil moussa Rikesh dayal 李雪梅郑英花张鸿大连医科大学附属第二医院心内科 116023 大连医科大学附属第二医院导管室 116023

目的:比较EXCEL与PARTNER支架单一植入治疗急性ST段抬高型心肌梗死(STEmI)的长期有效性和安全性。方法:328例入选患者,分为EXCEL组(175例)与PARTNER组(153例),行PCI治疗并单一植入EXCEL或PARTNER支架。随访12～70个月观察两组mACE的发... 详细信息

目的:比较EXCEL与PARTNER支架单一植入治疗急性ST段抬高型心肌梗死(STEmI)的长期有效性和安全性。方法:328例入选患者,分为EXCEL组(175例)与PARTNER组(153例),行PCI治疗并单一植入EXCEL或PARTNER支架。随访12～70个月观察两组mACE的发生率及两组生存时间。结果:两组间mACE发生率及心源性死亡、非致命性心肌梗死、TVR的发生率无统计学差异。两组间生存时间:EXCEL组:(58.77±1.51)个月;PARTNER组:(61.92±1.57)个月;两组生存时间比较,t=0.074,P=0.78。结论:国产生物可降解涂层与不可降解涂层药物支架在急性STEmI PCI治疗中有相似的安全性和有效性。在长期的临床随访中,心源性死亡、非致命性心肌梗死和靶血管血运重建以及mACE的发生率无显著差异。但本研究发现,术后很长时间(>59个月)内,EXCEL药物洗脱支架患者的生存率比PARTNER药物洗脱支架患者的生存率高,在冠心病真实世界中造成该现象可能与样本例数少有关,需要进一步进行多中心、更大样本的研究。

关键词：雷帕霉素生物可降解涂层经皮冠状动脉介入治疗抗血小板

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