检索结果-南通市图书馆

Exacerbated conceptus signaling does not favor establishment of pregnancy in beef cattle

Journal of Animal Science and Biotechnology 2019年第1期10卷 67-78页

作者： T.martins m.Sponchiado O.A.Ojeda-Rojas a.m.gonella-diaza E.O.S.Batista B.O.Cardoso C.C.Rocha A.C.Basso m.Binelli Department of Animal Reproduction School of Veterinary Medicine and Animal ScienceUniversity of Sao PauloPirassunungaSao PauloBrazil Department of Nutrition and Animal Production School of Veterinary Medicine and Animal ScienceUniversity of Sao PauloPirassunungaSao PauloBrazil In Vitro Brasil Mogi MirimSao PauloBrazil Department of Animal Sciences University of FloridaGainesvilleFloridaUSA

Background: Insufficient production of anti-luteolytic signals by the pre-attachment embryo is considered a major cause of pregnancy failure in *** tested the hypothesis that transfer of multiple blastocysts(n = 5/recipient) and progesterone(P4) supplementation amplify anti-luteolytic signaling and reduce embryonic losses in beef *** detected in estrus(D0; n = 104) were assigned randomly to receive 150 mg of injectable long-acting P4(iP4) or vehicle(non-iP4) on D4 and transcervical transfer of none or five,grade 1,not-frozen,in vitro-produced blastocysts,on *** development and time of structural luteolysis were monitored by *** P4 concentrations were determined on D4,D5 and D7,and daily between D14 and *** signaling was monitored by transcript abundance of interferon-stimulated gene 15(ISG15) in peripheral blood mononuclear cells isolated on D14,D16,D18 and *** embryonic mortality(EEm) was defined as the absence of ISG15 m RNA upregulation over time and/or luteal regression up to *** embryonic mortality(LEm) was defined as the absence of a conceptus with a heartbeat on pregnancy diagnosis at D30(PD30) after observing upregulation of ISG15 mRNA and extension of luteal *** cows presented conceptuses with heartbeat at ***: On D5,iP4-treated cows had P4 concentrations 2.07-fold greater than non-iP4 treated(P m animals showed a progressive increase in the abundance of ISG15 from D14 to ***4-treated cows detected pregnant at PD30 had 1.53-fold greater abundance of ISG15 mRNA between D14 and D20 than non-iP4 treated cows(P = 0.05).iP4 doubled the frequency of EEm while it did not affect *** PD30,embryonic survival was 37.0% vs.55.6% for iP4-treated *** *** of pregnant cows(71%)presented only a single viable ***: A substantial proportion of cows had EEm(31%) and LEm(20%) even after transferring

关键词： Corpus luteum Luteolysis Pregnancy Uterus

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Exacerbated conceptus signaling does not favor establishment of pregnancy in beef cattle.

引用

畜牧与生物技术杂志(英文版) 2019年第1期

作者： T.martins m.Sponchiado O.A.Ojeda-Rojas a.m.gonella-diaza E.O.S.Batista B.O.Cardoso C.C.Rocha A.C.Basso m.Binelli Department of Animal Reproduction，School of Veterinary medicine and Animal Science，University of S?o Paulo Department of Nutrition and Animal Production，School of Veterinary medicine and Animal Science，University of S?o Paulo Department of Animal Sciences，University of Florida

来源：评论

学校读者我要写书评

暂无评论

Perturbations in the uterine luminal fluid composition are detrimental to pregnancy establishment in cattle

引用

Journal of Animal Science and Biotechnology 2019年第1期10卷 56-66页

作者： Thiago martins Guilherme Pugliesi mariana Sponchiado Angela.m.gonella-diaza Oscar A.Ojeda-Rojas Frederich D.Rodriguez Roney S.Ramos Andrea C.Basso mario Binelli Department of Animal Reproduction School of Veterinary Medicine and Animal ScienceUniversity of Sao Paulo Department of Nutrition and Animal Production School of Veterinary Medicine and Animal ScienceUniversity of Sao Paulo University Corporation of Huila ABS Global In Vitro Brasil Department of Animal Sciences University of Florida

Background: A major,unresolved issue is how the uterine microenvironment determines pregnancy success in *** implantation,conceptus development depends on the uterine secretome(i.e.,histotroph).Despite its pivotal role,little is known about the dynamics of histotroph synthesis and changes in composition throughout the early diestrus and the relevance to pregnancy *** hypothesize that disturbances on histotroph composition affect the establishment of *** was to disturb histotroph composition at early diestrus and verify the effects on:(Exp.1) timing to restore its composition; and(Exp.2) pregnancy rate after multiple-embryo *** cycle of multiparous Nelore cows were synchronized and estrus was considered d 0(D0) of the *** was through flushing each uterine horn with 30 m L of DmPBS and collecting the resulting uterine luminal flushing(ULF) on D1; D4; D7; D1 + D4 + *** group remained *** Exp.1,ULF was collected on D7.5 from all animals and used for quantification of total protein concentration and abundance of *** Exp.2,three in vitro-produced embryos were transferred to the uterine horn ipsilateral to the ovary containing the CL on D7.5 and pregnancy was checked on D25 by ***: In Exp.1,ULF collection on D4 or D7 increased(1.5-to 2.2-folds) the total protein concentration and albumin *** collection on D1 did not alter(P > 0.10) these *** Exp.2,ULF collected on D4 or D7 decreased pregnancy rates to approximately half of that measured in the remaining ***: Subtle perturbations imposed to the native intrauterine milieu,such as those caused by a single,low-volume collection of ULF,profoundly disturbs intrauterine composition and pregnancy *** least 4 d were necessary for the uterus to recover its composition and the functional capacity to carry post-implantation gestation.

关键词： Albumin Embryo Histotroph Protein

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impact of hormonal modulation at proestrus on ovarian responses and uterine gene expression of suckled anestrous beef cows

引用

Journal of Animal Science and Biotechnology 2018年第1期9卷 77-90页

作者： manoel Francisco de Sá Filho Angela maria gonella-diaza mariana Sponchiado marcio Ferreira mendanha Guilherme Pugliesi Roney dos Santos Ramos Sónia Cristina da Silva Andrade Gustavo Gasparin Luiz Lehmann Coutinho marcelo Demarchi Goissis Fernando Silveira mesquita Pietro Sampaio Baruselli mario Binelli Departamento de Reproducao Animal FMVZ USP Sao Paulo SP Brazil Departamento de Genetica e Biologia Evolutiva IB-USP- Sao Paulo SP Brazil Laboratorio de Biotecnologia Animal ESALQ USP Av Padua Dias Piracicaba SP 11 Brazil Universidade Federal do Pampa Uruguaiana RS Brazil Universidade de Sao Paulo Faculdade de Medicina Veterinriae Zootecnia Departamento de Reprodcao Animal Avenida Duque de Caxias Norte 225 Pirassununga SP Zip Code 13635900 Brazil

Background： This study evaluated the impact of hormonal modulation at the onset of proestrus on ovarian response and uterine gene expression of beef ***： A total of 172 anestrous beef cows were assigned to one of four groups according to the treatment with estradiol cypionate（ECP） and/or equine chorionic gonadotropin（eCG） [CON（n = 43）, ECP（n = 43）, eCG（n = 44）and ECP ＋ eCG（n = 42）].Results： ECP-treated cows（ECP and ECP ＋ eCG groups） presented greater occurrence of estrus（44.6% vs. 65.4%; P = 0.01） and pregnancy per AI [47.1% vs. 33.3%; P = 0.07], but similar progesterone（P4） concentration at subsequent diestrus than cows not treated with ECP（CON and eCG groups）. Nonetheless, eCG-treated cows（eCG and ECP ＋ eCG groups） presented larger follicle at timed AI（12.6 ± 0.3 vs. 13.5 ± 0.3 mm; P = 0.03）, greater ovulation rate（96.5%vs. 82.6%; P = 0.008） and greater P4 concentration at d 6（3.9 ± 0.2 vs. 4.8 ± 0.2 ng/mL; P = 0.001） than cows not treated with eCG（CON and ECP groups）. Next, cows with a new corpus luteum 6 d after TAI were submitted to uterine biopsy procedure. Uterine fragments [CON（n = 6）, ECP（n = 6）] were analyzed by RNA-Seq and a total of 135 transcripts were differentially expressed between groups（73 genes up-regulated by ECP treatment）. Subsequently,uterine samples were analyzed by q PCR（genes associated with cell proliferation）. ECP treatment induced greater abundance of PTCH2（P = 0.07） and COL4 A1（P = 0.02）, whereas suppressed EGFR（P = 0.09） expression. Conversely, eCG treatment increased abundance of HB-EGF（P = 0.06）, ESR2（P = 0.09）, and ITGB3（P = 0.05）, whereas it reduced transcription of ESR1（P = 0.05）. Collectively, supplementation with ECP or eCG at the onset of proestrous of anestrous beef cows influenced ovarian responses, global and specific endometrial gene ***： Proestrus estradiol regulate the endometrial transcriptome, particularly stimulating proliferative activity in the endometrium.

关键词： Cattle eCG Endometrium Estradiol Transcriptome

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

引用

Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli m.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik m.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot m. Ait Tamlihat B. Aitbenchikh I. Aizenberg m. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt m. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi m. Algren m. Alhroob B. Ali H.m.J. Ali S. Ali S.W. Alibocus m. Aliev G. Alimonti W. Alkakhi C. Allaire B.m.m. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani m. Alvarez Estevez A. Alvarez Fernandez m. Alves Cardoso m.G. Alviggi m. Aly Y. Amaral Coutinho A. Ambler C. Amelung m. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel m.T. Anthony E. Antipov m. Antonelli F. Anulli m. Aoki T. Aoki J.A. Aparisi Pozo m.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin m. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia m. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.m. Baldin P. Balek E. Ballabene F. Balli L.m. Baltes W.K. Balunas J. Balz E. Banas m. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak m. Barakat E.L. Barberio D. Barberis m. Barbero m.Z. Barel K.N. Barends T. Barillari m-S. Barisits T. Barklow P. Baron D.A. Baron mo The ATLAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Perturbations in the uterine luminal fluid composition are detrimental to pregnancy establishment in cattle.

引用

畜牧与生物技术杂志(英文版) 2019年第1期

作者： Thiago martins Guilherme Pugliesi mariana Sponchiado Angelam.gonella-diaza Oscar A.Ojeda-Rojas Frederich D.Rodriguez Roney S.Ramos Andrea C.Basso mario Binelli Department of Animal Reproduction，School of Veterinary medicine and Animal Science，University of S?o Paulo Department of Nutrition and Animal Production，School of Veterinary medicine and Animal Science，University of S?o Paulo University Corporation of Huila ABS Global In Vitro Brasil Department of Animal Sciences，University of Florida

来源：评论

学校读者我要写书评

暂无评论

The Three-component One-pot Synthesis of 4,6-Diarylpyrimidin-2(1h)-ones and 9-Phenyl-8-oxa-10,12-diaza-tricyclo[7.3.1.0^(2,7)]trideca-2(7),3,5-trien-11-one

引用

复旦学报（自然科学版） 2007年第5期46卷 766-页

作者： F.Derikvand m.m.Heravi L.Ranjbar Department of Chemistry School of sciencesAzzahra University

1 Results Pyrimidinones (Pms) are a class of important heterocycles which have been well documented throughout the literature due to their biological importance. They exhibit a wide range of pharmaceutical and therapeutic properties[1].A rapid and efficient one-pot method for the synthesis of 4,6-diarylpyrimidin-2(1H)- ones and related heterocycles is *** condensation of acetophenone derivatives,aldehydes and urea in the presence of sulfamic acid was employed to synthesize a variety of pyrimid...

关键词： diarylopyrimidinones solvent-free reactions sulfamic acid multi-component reactions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

大二环型侧向穴醚的合成

引用

化学学报 1983年第8期41卷 730-733页

作者： J.m.Lehn 吴成泰 P.plumere Le Bel Institute Louis Pasteur University Strasbourg France Strasbourg France武汉大学化学系

本文报道一个大二环型侧向穴醚的合成方法借2,6-二（溴甲基）吡啶与β-（N-对甲苯磺酰基）丙氨酸酯缩合,产物经水解成酸后转换为酰氯（8）,8借高度稀释法与1,7-二氮杂-4,10-二硫杂环十二烷（5）缩合成环,然后还原羰基.脱对甲苯磺酰基后... 详细信息

本文报道一个大二环型侧向穴醚的合成方法借2,6-二（溴甲基）吡啶与β-（N-对甲苯磺酰基）丙氨酸酯缩合,产物经水解成酸后转换为酰氯（8）,8借高度稀释法与1,7-二氮杂-4,10-二硫杂环十二烷（5）缩合成环,然后还原羰基.脱对甲苯磺酰基后得大二环型侧向穴醚1,5,13,17,28-五氮杂-20,25-二硫杂-三环[15,5,5,17,11]-廿八-7,9,11（28）三烯（2）.

关键词：穴醚二氯甲烷氯代烃硫杂环十二烷环型侧向二硼烷对甲苯磺酰基收率甲酞胺

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Synthesis of lateral macrobicyclic cryptand

引用

Chinese Journal of Chemistry 1983年第1期1卷 67-70页

作者： J.m.LEHN WU Cheng-tai P.PLUmERE Le Bel Institute,Louis Pasteur University,Strasbourg,France Department of Chemistry,Wuhan University,Wuhan,China. Le Bel Institute Louis Pasteur University Strasbourg France

This paper deals with the synthesis of a new lateral macrobicyclic cryptand ***-tion of 2,6-di（bromomethyl）pyridine with 3-（n-tosylamino）methyl propionate in the presence ofanhydrous KCOat room temperature gave 5 which was hydrolyzed to *** of the latter withexcess sulfonyl chloride afforded 2,6-di（4’-chloroformyl-2’-tosyl-2’-azabutyl）pyridine（7）.Pentaaza-1,5,13,17,28-dithia-20,25-tricyclo[15,5,5,1]-octacosa-7,9,11（28）-triene（10）has been synthesized bythe following sequence of reactions:Condensation of 7 with 1,7-diaza-4,10-dithia-dodecane（3）by highdilution technique in toluene-THF at room femperature afforded 8 which was reduced by diboranein THF solution to give *** of 9 with sodium anthracene in monoglyme produced 10.

关键词： Synthesis of lateral macrobicyclic cryptand

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Seismic Oceanography:A New Geophysical Tool to Investigate the Thermohaline Structure of the Oceans

Seismic Oceanography:A New Geophysical Tool to Investigate t...

引用

中国科学院地质与地球物理研究所2012年度（第12届）学术年会

作者： Haibin Song Luis m.Pinheiro Barry Ruddick Xinghui Huang Key Laboratory of Petroleum Resources Research Institute of Geology and GeophysicsChinese Academy of Sciences Departamento de Geociencias and CESAm Universidade de AveiroAveiroPortugal Department of Oceanography Dalhousie UniversityHalifaxNova ScotiaCanada

*** Seismic oceanography is a new cross discipline between seismology and physical *** consists of the apphcation of the multichannel seismic reflection method, commonly used in the oil industry to image the subsurface geological structure,to the investigation of the therm ohaline fine structure of the *** apphcation of the seismic reflection method for this purpose was first reported by gonella and michon(1988),but that

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：