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Can tranexamic acid change preoperative anemia management during total joint arthroplasty?

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World Journal of Orthopedics 2015年第7期6卷 521-527页

作者： Duy l Phan Joseph B Rinehart Ran Schwarzkopf Department of Orthopaedic Surgery University of California Department of Anesthesiology University of California

AIM: To investigate the postoperative transfusion and complication rates of anemic and nonanemic total joint arthroplasty patients given tranexamic acid(TXA).METHODS: A cross-sectional prospective study was conducted of primary hip and knee arthroplasty cases performed from 11/2012 to 6/2014. Exclusion criteria included revision arthroplasty, bilateral arthroplasty, acute arthroplasty after fracture, and contraindication to TXA. Patients were screened prior to surgery, with anemia was defined as hemoglobin of less than 12 g/d l for females and of less than 13 g/d l for males. Patients were divided into four different groups, based on the type of arthroplasty(total hip or total knee) and hemoglobin status(anemic or nonanemic). Intraoperatively, a.l patients received 2 g of intravenous TXA during surgery. Postoperatively, a.logeneic blood transfusion(ABT) was directed by both clinical symptomsand relative hemoglobin change. Complications were recorded within the first two weeks after surgery and included thromboembolism, infection, and wound breakdown. The differences in transfusion and complication rates, as well as the relative hemoglobin change, were compared between anemic and nonanemic ***: A total of 232 patients undergoing primary joint arthroplasty were included in the study. For the total hip arthroplasty cohort, 21%(18/84) of patients presented with preoperative anemia. Two patients in the anemic group and two patients in the nonanemic group needed ABTs; this was not significantly different(P = 0.20). One patient in the anemic group presented with a deep venous thromboembolism while no patients in the nonanemic group had an acute complication; this was not significantly different(P = 0.21). For nonanemic patients, the average change in hemoglobin was 2.73 ± 1.17 g/d l. For anemic patients, the average change in hemoglobin was 2.28 ± 0.96 g/d l. Between the two groups, the hemoglobin difference of 0.45 g/d l was not significant(P = 0.13). For the t

关键词： Total knee replacement Tranexamic acid Total hip replacement Preoperative anemia

Complementary and alternative medications in hepatitis C infection

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World Journal of Hepatology 2014年第1期6卷 9-16页

作者： Dina.l Halegoua-De Marzio Jonathan M Fenkel Division of Gastroenterology and Hepatology Thomas Jefferson University Hospital

Chronic hepatitis C(CHC) infection affects almost 3% of the global population and can lead to cirrhosis, liver fa.lure, and hepatocellular carcinoma in a significant number of those infected. Until recently, the only treatments ava.la.le were pegylated interferon and ribavirin, which traditiona.ly were not very effective and have considera.le side effects. For this reason, interest in complementary and alternative medications(CAM) in the management of hepatitis C has been investigated. Some CAM has demonstrated therapeutic potential in chronic hepatitis C treatment. Unfortunately, some CAM has been shown to have the potential to cause drug-induced liver injury. This article will review and evaluate many of the natural molecules that interact with the hepatitis C virus(HCV) life cycle and discuss their potential use and safety in HCV therapy, as well as highlight some important interactions between medical and complementary treatments.

关键词： Hepatitis C infection Natural molecules Direct acting antivirals Hepatotoxicity Herbal treatments

Non-invasive stimulation techniques to relieve abdominal/pelvic pain: Is more always better?

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World Journal of Gastroenterology 2017年第20期23卷 3758-3760页

作者： Marie-Philippe Harvey Alain Watier émilie Dufort Rouleau Guillaume léonard Research Centre on Aging Universitéde Sherbrooke Department of Gastroenterology Sherbrooke University Hospital Centre Department of Pharmacy Sherbrooke University Hospital Centre School of Rehabilitation University of Sherbrooke

Chronic abdominal and pelvic pain is a common condition that has significant impact on quality of life,and causes billions of dollars in direct and indirect *** data suggest that transcranial direct current stimulation(t DCS),alone or in combination with transcutaneous electrical nerve stimulation(TENS),could be a promising therapeutic avenue to reduce chronic *** encouraging results coming from these studies prompted us to try combining TENS and t DCS in 4 of our patients who suffered from chronic abdominal/pelvic pain and to compare the effect with 5other patients who received TENS *** intensity was assessed with a visual analog scale before,during and after the *** observed that there was a slight decrease in pain which was similar in both patient groups(TENS alone and TENS combined with t DCS).These observations suggest that combining TENS and t DCS in patients suffering from chronic pelvic and/or abdominal pain produces no additional benefit,compared to TENS *** studies,looking at the effect of several/consecutive TENS and t DCS sessions should be conducted.

关键词： Transcranial direct current stimulation Transcutaneous electrical nerve stimulation Pelvic pain Abdominal pain Chronic pain

Fundamental Groups of Real Toric Spaces over Simple Polytopes

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Acta Mathematica Sinica,English Series 2022年第10期38卷 1887-1900页

作者： Zhi lU Song ZHANG School of Mathematical Sciences Fudan UniversityShanghai 200433P.R.China

In this paper we study the cubical stuctures and fundamental groups of real toric *** give an explicit presentation of the fundamental group of the real toric space over a simple *** using this presentation,we give a ... 详细信息

关键词： Real toric space fundamental group simple polytope real Buchstaber invariant

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Research on high bandwidth power supply

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Radiation Detection Technology and Methods 2022年第3期6卷 409-417页

作者： P.liu F.l.long Y.li Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China

Background Fourth-generation photon sources like Free Electron lasers(FEl)and Diffraction-limited Storage Rings(DlSR)have high requirements for beam *** the case of DlSR sources,a set of high-performance fast orbit feedback system(FOFB)is needed to correct the beam orbit quickly and *** FOFB system has four key components,which is BPM,orbit feedback calculation,fast correction magnet and fast corrector power *** FOFB gives the correction command and controls the fast corrector power supply to drive the fast correction magnet to correct the beam quickly and *** corrector power supply has an important impact on the performance of *** corrector power supply needs to have high bandwidth and low output current *** The new GaN power device is used to solve the restriction of the high-speed *** switching frequency of the power supply is increased to 300 *** control system is designed to improve the bandwidth and optimize the output current *** modeling analysis of the key parts of the system is given and the simulation experiments are carried out with *** and conclusion The test results showed that bandwidth of the designed power supply is 20 *** step response time is 18us and output current ripple is lower than 1 mA.

关键词： Photon source FOFB High bandwidth Ma.lAB GaN

Observer design for a class of linear time-varying systems 36

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Observer design for a class of linear time-varying systems

Observations of NO_2 and O_3 during Thunderstorm Activity Using Visible Spectroscopy

第36届中国控制会议

作者： l.T.li G.R.Duan Center for Control Theory and Guidance Technology Harbin Institute of Technology

ISBN: (纸本)9781538629185

The problem of observer design for a class of linear time-varying system is researched in this paper. An augmented linear time-varying system is proposed to extent the application of the previous results. Moreover, using the observa.le block companion form of the augmented linear time-varying system, this paper presents an algorithm of observer design. Compared with other observer design approaches, the prominent feature of the algorithm is that of simplifying the computational ***, simulations are designed in linear time-varying system and results are presented to demonstrate validity of the proposed algorithm.

关键词： augmented linear time-varying systems observability block companion form observer design

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Advances in Atmospheric Sciences 1996年第3期13卷 359-374页

作者： D.B.Jadhav a.l.londhe S.Bose Indian Institute of Tropical Meteorology Dr.Homi Bhabha MargPashanPune-411008MaharashtraIndiaIndian Institute of Tropical MeteorologyDr.Homi Bhabha MargPashanPune-411008MaharashtraIndiaIndian Institute of Tropical MeteorologyDr.Homi Bhabha MargPashanPune-411008MaharashtraIndia

Simultaneous observations for the total column densities of NO2,O3 and H2O were carried on using the porta.le Spectrometer (438-450 nm and 400-450 nm) and the visible Spectrometer (544.4-628 nm) during premonsoon thunderstorms and embedded ha.l storm activity at Pune (18°32'N & 73°51'E),*** observations confirm the fact that there is an increase in O3 and NO2 column densities during *** increase in O3 was observed following onset of thunderstorm,while the increase in NO2 was observed only after the thunder flashes *** implies that the production mechanisms for O3 and NO2 in thunderstorm are *** observed column density of NO,value (1 to 3×1017molecules cm-2) during thunderstorm activity is 10 to 30 times higher than the value (1×10th molecules cm-2) of a normal day total column *** spectrometric observations and observations of thunder flashes by electric field meter showed that 6.4×1025molecules/flash of NO2 are *** increased to-oil column density of ozone during thunderstorm period is 1.2 times higher than normal (clear) day ozone *** multiple scattering in the clouds is estimated from H2O and O2 absorption bands in the visible spectral region Considering this effect the calculated amount of ozone added in the global atmosphere due to thunderstorm activity is 0.26 to 0 52 DU,and the annual production of ozone due to thunderstorm activity is of the order of 4.02×10 molecules/year The annual NO2 production may be of the order of 2.02×1035molecules/year.

关键词： Visible Spectroscopy Thunderstorm Ozone production NO2 production Atmospheric electricity lightning flashes. Multiple scattering factor

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Kinetics and mechanistic study of n-alkane hydroisomerization reaction on Pt-doped g-alumina catalyst

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Petroleum 2017年第4期3卷 489-495页

作者： Abhishek Dhar Rohit l.Vekariya Pushan Sharma Department of Science&Technology Government of West BengalVigyan Chetana Bhavan Plot no.26/BBlock DDSector e ISalt LakeKolkata 64India School of Chemical Engineering Fuzhou UniversityFuzhou 350116Fujian ProvincePR China Department of Mechanical Engineering Indian Institute of TechnologyDelhiHauz KhasNew Delhi 110016India

The catalysts g-alumina(GA,the reference catalyst)and Pt doped g-alumina(PGA-s)were synthesized using a simple sol-gel technique,in which at first preparation of porous base(GA),then impregnation of platinum salt over the base and fina.ly reduction of platinum in the surface of the support were *** catalysts prepared in different mole ratios of Pt:Al as 2:1,1:1 and 1:2 are named as PGA-1,PGA-2 and PGA-3 *** isomerization of n-alkanes(n-hexane,nheptane and n-octane)were investigated over the synthesized *** 2-methyl pentane(2-MP),2,2-dimethyl pentane(2,2-DMP)and 2,3-dimethyl hexane(2,3-DMH)are the major products of respective isomerization of n-hexane,n-heptane and n-octane,besides a sma.l amount of other branched isomers are also *** product distribution is compara.le to that reported for Pt based other *** optimal mole ratios of Pt:Al is 1:1(PGA-2)gives quite good catalytic activity for isomerization of *** through in reusability study,PGA-2 gives better performance than *** have mainly focused on kinetic study,reaction mechanism behind isomerization and calculated the order of reactions and activation energies of the isomerization reactions in the present work.

关键词： Isomerization n-alkanes Catalyst Reaction mechanism Kinetics study Activation energy

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COMPUTED TOMOGRAPHIC GUIDANCE STEREOTAXIS IN THE MANAGEMENT OF INTRACRANIAl MASS lESIONS

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中华神经外科杂志 1993年第6期 50-51页

作者： Athanasio J.Spanos,Robert l.Martuza Neurosurgenon Research Fellow in Surgery Harvard Medical School Boston U.S.A. Associate Visiting Neurosurgeon Harvard Medical School Boston U.S.A.

The stereotactic neurosurgical resection,which was named by the greek word(?),began with the pioneering publica-tion of Horsley and Clarke in *** ad-vent of computed axial tomography has notonly provided new insights ... 详细信息

关键词： COMPUTED TOMOGRAPHIC GUIDANCE STEREOTAXIS IN THE MANAGEMENT OF INTRACRANIAl MASS lESIONS