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某小型发电柴油机应急运行线路设计

移动电源与车辆 2024年第3期55卷 1-5页

作者：王瑞成丁德宇刘桃生海军士官学校安徽蚌埠233012 海军92038部队山东青岛266100

本文由一起小型车载10kW发电柴油机起动故障为引,在分析故障原因的基础上,进行了应急运行线路设计和实施方法,并确保机组在应急运行状态下具备基本的保护功能,避免机组发生重大故障,有效提高车载机动设备的供电可靠性。

关键词：线路设计应急运行故障检修

Dispersal of invasive species by drifting

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Current Zoology 2011年第6期57卷 818-827页

作者： M.C. VAN RIEL G. VAN deR VELde A. BIJ de VAATE Radboud University Nijmegen Institute for Water and Wetland Research Department of Animal Ecology and Ecophysiology Section Aquatic Animal Ecology Heyendaalseweg 135 6525 AJ Nijmegen The Netherlands Team Freshwater Ecology DLO-Alterra P.O. Box 47 6700 AA Wageningen The Netherlands Netherlands Centre for Biodiversity Naturalis EO. Box 9517 2300 RA Leiden The Netherlands Waterfauna Hydrobiologisch Adviesbureau Oostrandpark 30 8212 AP Lelystad The Netherlands

Drifting can be an effective way for aquatic organisms to disperse and colonise new areas. Increasing connectivity between European large rivers facilitates invasion by drifting aquatic macroinvertebrates. The present study shows that high abundances of invasive species drift in the headstream of the river Rhine. Dikerogammarus villosus and Chelicorophium cur- vispinum represented up to 90% of the total of drifting macroinvertebrates. Drift activity shows seasonal and diel patterns. Most species started drifting in spring and were most abundant in the water column during the summer period. Drift activity was very low during the winter period. Diel patterns were apparent; most species, including D. villosus, drifted during the night. Drifting macroinvertebrates colonised stony substrate directly from the water column. D. villosus generally colonised the substrate at night, while higher numbers of C. curvispinum colonised the substrate during the day. It is very likely that drifting functions as a disper- sal mechanism for crustacean invaders. Once waterways are connected, these species are no longer necessarily dependent on dispersal vectors other than drift for extending their distribution range

关键词： Amphipods Invaders Colonization Drift Daily rhythms Seasonal variation

The Global Bifurcation of a Cubic System

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Acta Mathematicae Applicatae Sinica 2006年第2期22卷 325-332页

作者： de-sheng Shang Mao-an Han Jin-ping Sun School of Mathematics and Information Science Shandong University of Technology Zibo 255049 China School of Mathematical Sciences Shanghai Normal University Shanghai 200234 China

In this paper, we study the perturbation of certain of cubic system. By using the method of multi-parameter perturbation theory and qualitative analysis, we infer that the system under consideration can have five limi... 详细信息

关键词： Perturbation bifurcation cubic system limit cycle Homoclinic loop

Parallel Algorithms for Large-scale Linearly Constrained Minimization Problem

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Acta Mathematicae Applicatae Sinica 2014年第3期30卷 707-720页

作者： Cong-ying HAN Fang-ying ZHENG Tian-de GUO Guo-ping HE School of Mathematical Sciences University of the Chinese Academy of Sciences department of Mathematical Science Zhejiang Sci-Tech University College of Information Science and Engineering Shandong University of Science and Technology

In this paper, two PVD-type algorithms are proposed for solving inseparable linear constraint optimization. Instead of computing the residual gradient function, the new algorithm uses the reduced gradients to construct the PVD directions in parallel computation, which can greatly reduce the computation amount each iteration and is closer to practical applications for solve large-scale nonlinear programming. Moreover, based on an active set computed by the coordinate rotation at each iteration, a feasible descent direction can be easily obtained by the extended reduced gradient method. The direction is then used as the PVD direction and a new PVD algorithm is proposed for the general linearly constrained optimization. And the global convergence is also proved.

关键词： nonlinear programming large-scale minimization parallel algorithm constrained convex opti-mization

轻度子痫前期实验室血液指标危险因素及诊断价值分析

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中国妇幼保健 2024年第12期39卷 2222-2227页

作者：林蓉蓉邱德稳高国栋江西省妇幼保健院检验科江西南昌330006

目的探讨轻度子痫前期实验室血液指标变化特征,寻找轻度子痫前期的危险因素,分析各研究指标对轻度子痫前期的诊断价值。方法选择2020年12月—2021年12月江西省妇幼保健院孕20周后正常孕妇158例作为对照组,同期收治104例轻度子痫前期... 详细信息

目的探讨轻度子痫前期实验室血液指标变化特征,寻找轻度子痫前期的危险因素,分析各研究指标对轻度子痫前期的诊断价值。方法选择2020年12月—2021年12月江西省妇幼保健院孕20周后正常孕妇158例作为对照组,同期收治104例轻度子痫前期孕妇作为观察组。比较两组在血常规、生化、凝血、甲功及炎症指标的变化特征,用logistic回归分析上述实验室血液指标的危险因素,并运用受试者工作曲线(ROC)分析实验室血液指标对轻度子痫前期诊断价值。结果血常规指标中,两组在红细胞(RBC)、白细胞(WBC)、中性粒细胞比率(NEU)、血小板压积(PCT)、平均血小板体积(MPV)及血小板分布宽度(PDW)水平比较差异均有统计学意义(均P0.05);(4)在生化指标中,两组在肝功能上,观察组在谷草转氨酶(AST)、谷氨酰转肽酶(GGT)、碱性磷酸酶(ALP)及乳酸脱氢酶(LDH)水平均高于对照组(Pk)、肌酸激酶同工酶(CkMB)及ɑ-羟丁酸(HBDH)水平上,差异均无统计学意义(均P>0.05);在血脂上,观察组总胆固醇(TCHOL)、三酰甘油(TG)、高密度脂蛋白(HDL)、载脂蛋白A1(APOA1)及载脂蛋白B(APOB)水平均高于对照组(P<0.05);在电解质水平上,观察组镁(MG)及磷(P)水平均高于对照组(P<0.05)。结论通过对实验室血液指标的检测,及早发现孕妇的子痫前期,以防止母婴不良妊娠结局。

关键词：血液指标轻度子痫前期危险因素诊断价值

Psychological impact of chronic hepatitis C:Comparison with other stressful life events and chronic diseases

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World Journal of Gastroenterology 2006年第10期12卷 1545-1550页

作者： Laurent Castera Aymery Constant Pierre-Henri Bernard Victor de Ledinghen Patrice Couzigou Service d'Hépato-Gastroentérologie Centre Hospitalier Universitaire de Bordeaux Hpital Haut Lévêque 33604 Pessac France Service d'Hépato-Gastroentérologie Centre Hospitalier Universitaire de Bordeaux Hpital St-André 33000 Bordeaux France Laboratoire de Psychologie de la Santé EA 3662 Université Victor Segalen Bordeaux-2 33000 Bordeaux France Service d'Hépato-Gastroentérologie Centre Hospitalier Universitaire de Bordeaux Hpital St-André33000 BordeauxFrance Service d'Hépato-Gastroenterologie Centre Hospitalier Universitaire de Bordeaux Hpital Haut Lévêque33604 PessacFrance

AIM： To examine the psychological impact of chronic hepatitis C （CHC） diagnosis in a large cohort of CHC patients as compared with other stressful life events and chronic diseases carrying a risk of life-threatening complications. METHODS： One hundred and eighty-five outpatients with compensated CHC were asked to self-grade, using a 100-mm visual analogue scale （VAS）, the degree of stress caused by the learning of CHC diagnosis and the perceived severity of their disease. Diagnosis-related stress was compared to four other stressful life events and perceived CHC severity was compared to four other common chronic diseases. RESULTS： Learning of CHC diagnosis was considered a major stressful event （mean ± SD scores： 72±25）, significantly less than death of a loved-one （89±13, P〈0.0001） and divorce （78 ± 23, P〈0.007）, but more than job dismissal （68 ± 30, P〈 0.04） and home removal （26±24, P〈 0.0001）. CHC was considered a severe disease （74± 19）, after AIDS （94±08, P〈 0.001） and cancer （91± 11, P〈 0.001）, but before diabetes （66±23, P〈0.001） and hypertension （62±20, P〈0.001）. Perceived CHC severity was not related to the actual severity of liver disease, assessed according to Metavir fibrosis score. In multivariate analysis, diagnosisrelated stress was related to perceived disease severity （P〈0.001）, trait anxiety （P〈 0.001） and infection through blood transfusion （P〈 0.001）. CONCLUSION： Our results show the considerable psychological and emotional burden that a diagnosis of CHC represents, even in the absence of significant liver disease. They should be taken into account when announcing a diagnosis of CHC in order to reduce its negative effects.

关键词： Hepatitis C Stressful life event Perceived severity Visual analogue scale

EH4电磁成像系统在西南含盐含石膏隧洞勘察中的应用探析

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贵州地质 2024年第1期41卷 42-50页

作者：宋启文陈德靖杨海龙贵州省地矿局地球物理地球化学勘查院贵州贵阳550018

本文介绍了EH4电磁成像系统的原理、工作方法和资料处理,通过EH4电磁成像系统在云南禄丰黑井隧洞勘察中的应用实例,提出该方法可以应用在含盐和石膏隧道勘察中,在勘查地质构造、岩石破碎带和含盐、含石膏地层方面有很好的效果,为这类隧... 详细信息

本文介绍了EH4电磁成像系统的原理、工作方法和资料处理,通过EH4电磁成像系统在云南禄丰黑井隧洞勘察中的应用实例,提出该方法可以应用在含盐和石膏隧道勘察中,在勘查地质构造、岩石破碎带和含盐、含石膏地层方面有很好的效果,为这类隧道勘察提供了科学依据。

关键词： EH4电磁成像系统隧洞勘察

Effectiveness of Helicobacter pylori eradication in the treatment of early-stage gastric mucosa-associated lymphoid tissue lymphoma:An up-to-date meta-analysis

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World Journal of Gastroenterology 2023年第14期29卷 2202-2221页

作者： Fabian Fellipe Bueno Lemos Caroline Tianeze de Castro Mariana Santos Calmon Marcel Silva Luz Samuel Luca Rocha Pinheiro Clara Faria Souza Mendes dos Santos Gabriel Lima Correa Santos Hanna Santos Marques Henrique Affonso delgado kádima Nayara Teixeira Cláudio Lima Souza Márcio Vasconcelos Oliveira Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029094BahiaBrazil Instituto de Saúde Coletiva Universidade Federal da BahiaSalvador 40110040BahiaBrazil Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45029094BahiaBrazil Campus Toledo Universidade Federal do ParanáToledo 85919899ParanáBrazil

BACkGROUND Gastric mucosa-associated lymphoid tissue(MALT)lymphoma(GML)is usually a low-grade B-cell neoplasia strongly associated with Helicobacter pylori(***)-induced chronic *** practice guidelines currently recommend *** eradication as the preferred initial treatment for early-stage *** determine the practical effect of bacterial eradication as the sole initial therapy for early-stage GML,an updated analysis and review of available evidence is *** To perform a meta-analysis to assess the rate of complete remission(CR)of ***-positive early-stage GML following bacterial *** We performed independent,computer-assisted literature searches using the PubMed/MEDLINE,Embase,and Cochrane Central databases through September *** and retrospective observational studies evaluating the CR of early-stage GML following bacterial eradication in ***-positive *** risk of bias was assessed using Joanna Briggs Institute(JBI)Critical Appraisal *** pooled estimate of the complete histopathological remission rate and respective confidence intervals(95%CI)were calculated following the random-effects *** and inconsistency were assessed using Cochran’s Q test and I2 statistic,and heterogeneity was defined as P50%,*** and meta-regression analyses were conducted to explore potential sources of *** The titles and abstracts of 1576 studies were screened;96 articles were retrieved and selected for full-text ***,61 studies were included in the proportional meta-analysis(P-MA).Forty-six were prospective and fifteen were retrospective uncontrolled,single-arm,observational *** overall risk of bias was low to moderate in all but a single report,with an average critical appraisal score across all studies of 79.02%.A total of 2936 ***-positive early-stage GML patients,in whom *** was successfully eradicated,were incl

关键词： Lymphoma B-cell Marginal zone Gastric mucosa-associated lymphoid tissue lymphoma Stomach lymphoma Helicobacter pylori Therapeutics Eradication therapy

Tousled-like kinase 1:a novel factor with multifaceted role in mCRPC progression and development of therapy resistance

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Cancer Drug Resistance 2022年第1期5卷 93-101页

作者： Md Imtiaz khalil Arrigo de Benedetti department of Biochemistry and Molecular Biology LSU Health Sciences CenterShreveportLA 71103USA

Standard treatment for advanced Prostate Cancer(PCa)consists of androgen deprivation therapy(ADT),but ultimately fails,resulting in the incurable phase of the disease:metastatic castration-resistant prostate cancer(mCRPC).Targeting PCa cells before their progression to mCRPC would greatly improve the outcome,if strategies could be devised selectively targeting androgen receptor(AR)-dependent and/or independent compensatory pathways which promote mCRPC *** therapy by targeting the DNA damage response(DDR)along with ADT has been limited by general toxicity,and a goal of clinical trials is how to target the DDR more *** recent years,our lab has identified a key role for the DDR kinase,TLk1,in mediating key aspects of adaptation to ADT,first by promoting a cell cycle arrest(through the TLk1>NEk1>ATR>Chk1 kinase cascade)under the unfavorable growth conditions(androgen deprivation),and then by reprogramming the PCa cells to adapt to androgen-independent growth via the NEk1>YAP/AR>CRPC *** addition,TLk1 plays a key anti-apoptotic role via the NEk1>VDAC1 regulation on the intrinsic mitochondrial apoptotic pathway when the DDR is ***,TLk1 was recently identified as having an important role in motility and metastasis via regulation of the kinases Mk5/PRAk and AkT(indirectly via AkTIP).

关键词： TLk1 NEk1 YAP1 VDAC1 DNA damage response prostate cancer metastatic castration-resistant prostate cancer drug resistance in mCRPC