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Robust Reversible Audio Watermarking Scheme for Telemedicine and Privacy Protection

Computers, Materials & Continua 2022年第5期71卷 3035-3050页

作者： Xiaorui Zhang Xun Sun Xingming Sun Wei Sun Sunil kumar jha Engineering Research Center of Digital Forensics Ministry of EducationJiangsu Engineering Center of Network MonitoringSchool of Computer and SoftwareNanjing University of Information Science&TechnologyNanjing210044China Wuxi Research Institute Nanjing University of Information Science&TechnologyWuxi214100China Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment Technology Nanjing University of Information Science&TechnologyNanjing210044China IT Fundamentals and Education Technologies Applications University of Information Technology and Management in RzeszowRzeszow Voivodeship100031Poland

The leakage of medical audio data in telemedicine seriously violates the privacy of *** order to avoid the leakage of patient information in telemedicine,a two-stage reversible robust audio watermarking algorithm is proposed to protect medical audio *** scheme decomposes the medical audio into two independent embedding domains,embeds the robust watermark and the reversible watermark into the two domains *** order to ensure the audio quality,the Hurst exponent is used to find a suitable position for watermark *** to the independence of the two embedding domains,the embedding of the second-stage reversible watermark will not affect the first-stage watermark,so the robustness of the first-stage watermark can be well *** the second stage,the correlation between the sampling points in the medical audio is used to modify the hidden bits of the histogram to reduce the modification of the medical audio and reduce the distortion caused by reversible *** experiments show that this scheme has strong robustness against signal processing operations such as MP3 compression of 48 db,additive white Gaussian noise(AWGN)of 20 db,low-pass filtering,resampling,re-quantization and other attacks,and has good imperceptibility.

关键词： Telemedicine privacy protection audio watermarking robust reversible watermarking two-stage embedding

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A Robust 3-D Medical Watermarking Based on Wavelet Transform for Data Protection

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Computer Systems Science & Engineering 2022年第6期41卷 1043-1056页

作者： Xiaorui Zhang Wenfang Zhang Wei Sun Xingming Sun Sunil kumar jha Engineering Research Center of Digital Forensics Ministry of EducationJiangsu Engineering Center of Network MonitoringSchool of Computer and SoftwareNanjing University of Information Science&TechnologyNanjing210044China Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment Technology(CICAEET) Nanjing University of Information Science&TechnologyNanjing210044China Wuxi Research Institute Nanjing University of Information Science&TechnologyWuxi214100China IT Fundamentals and Education Technologies Applications University of Information Technology and Management in RzeszowRzeszowVoivodeship100031Poland

In a telemedicine diagnosis system,the emergence of 3D imaging enables doctors to make clearer judgments,and its accuracy also directly affects doctors’diagnosis of the *** order to ensure the safe transmission and storage of medical data,a 3D medical watermarking algorithm based on wavelet transform is proposed in this *** proposed algorithm employs the principal component analysis(PCA)transform to reduce the data dimension,which can minimize the error between the extracted components and the original data in the mean square ***,this algorithm helps to create a bacterial foraging model based on particle swarm optimization(BF-PSO),by which the optimal wavelet coefficient is found for embedding and is used as the absolute feature of watermark embedding,thereby achieving the optimal balance between embedding capacity and imperceptibility.A series of experimental results from MATLAB software based on the standard MRI brain volume dataset demonstrate that the proposed algorithm has strong robustness and make the 3D model have small deformation after embedding the watermark.

关键词： 3-D medical watermarking robust watermarking PCA BF-PSO

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Sleep alterations in mammals:Did aquatic conditions inhibit rapid eye movement sleep?

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Neuroscience Bulletin 2012年第6期28卷 746-758页

作者： Vibha Madan Sushil k.jha School of Life Sciences Jawaharlal Nehru UniversityNew Delhi-110067India

Sleep has been studied widely in mammals and to some extent in other vertebrates. Higher vertebrates such as birds and mammals have evolved an inimitable rapid eye movement （REM） sleep state. During REM sleep, postural muscles become atonic and the temperature regulating machinery remains suspended. Although REM sleep is present in almost all the terrestrial mammals, the aquatic mammals have either radically reduced or completely eliminated REM sleep. Further, we found a significant negative correlation between REM sleep and the adaptation of the organism to live on land or in water. The amount of REM sleep is highest in terrestrial mammals, significantly reduced in semi-aquatic mammals and completely absent or negligible in aquatic mammals. The aquatic mammals are obligate swimmers and have to sur- face at regular intervals for air. Also, these animals live in thermally challenging environments, where the conductive heat loss is approximately -90 times greater than air. Therefore, they have to be moving most of the time. As an adaptation, they have evolved unihemispheric sleep, during which they can rove as well as rest. A condition that immobilizes muscle activity and suspends the thermoregulatory machinery, as happens during REM sleep, is not suitable for these animals. It is possible that, in accord with Darwin＇s theory, aquatic mammals might have abolished REM sleep with time. In this review, we discuss the possibility of the intrinsic role of aquatic conditions in the elimination of REM sleep in the aquatic mammals.

关键词： aquatic mammals aquatic adaptation mammalian sleep phylogenetic evolution

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Articulating beneficial rhizobacteria-mediated plant defenses through induced systemic resistance:A review

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Pedosphere 2023年第4期33卷 556-566页

作者： Aniruddh RABARI Janki RUPARELIA Chaitanya kumar jha Riyaz Z.SAYYED Debasis MITRA Ankita PRIYADARSHINI Ansuman SENAPATI Periyasamy PANNEERSELVAM Pradeep k.DAS MOHAPATRA Department of Microbiology and Biotechnology Gujarat UniversityAhmedabadGujarat 380006(India) Microbiology Department Gujarat Arts and Science CollegeEllisbridgeAhmedabadGujarat 380006(India) Department of Microbiology PSGVP Mandal's ArtsScience and Commerce CollegeMaharashtraShahada 425409(India) Department of Microbiology Raiganj UniversityRaiganjUttar DinajpurWest Bengal 733134(India) Crop Production Division Indian Council of Agriculture Research(ICAR)-National Rice Research InstituteCuttackOdisha 753006(India) Professor A.k.B.Environment Conservation Centre Raiganj UniversityRaiganjWest Bengal 733134(India)

Induced systemic resistance(ISR)is a mechanism by which certain plant beneficial rhizobacteria and fungi produce immunity,which can stimulate crop growth and resilience against various phytopathogens,insects,and *** beneficial rhizobacteria and fungi improve plant performance by regulating hormone signaling,including salicylic acid(SA),jasmonic acid(JA),prosystemin,pathogenesis-related gene 1,and ethylene(ET)pathways,which activate the gene expression of ISR,the synthesis of secondary metabolites,various enzymes,and volatile compounds that ultimately induce defense mechanisms in *** protect themselves from disease,plants have various advanced defense mechanisms in which local acquired resistance,systemic gene silencing,systemic wound response,systemic acquired resistance(SAR),and ISR are *** rhizobacteria activate the SA-dependent SAR pathway by producing SA at the root’s *** contrast,other rhizobacteria can activate different signaling pathways independent of SA(SA-independent ISR pathways)such as those dependent on JA and ET *** main objective of this review is to provide insight into the types of induced resistance utilized for plant *** to this,the genetic approaches used to suppress disease-causing genes,i.e.,RNA interference and antisense RNA,which are still underutilized in sustainable agriculture,along with the current vision for virus-induced gene silencing are also discussed.

关键词： biocontrol gene silencing local acquired resistance phytohormone secondary induced resistances signaling pathways systemic acquired resistance

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Locus Coeruleus Acid-Sensing Ion Channels Modulate Sleep–Wakefulness and State Transition from NREM to REM Sleep in the Rat

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Neuroscience Bulletin 2021年第5期37卷 684-700页

作者： Fayaz A.Mir Sushil k.jha School of Life Sciences Jawaharlal Nehru UniversityNew Delhi 110067India

The locus coeruleus(LC) is one of the essential chemoregulatory and sleep–wake(S–W) modulating centers in the brain. LC neurons remain highly active during wakefulness, and some implicitly become silent during rapid eye movement(REM) sleep. LC neurons are also involved in CO_2-dependent modulation of the respiratory drive. Acid-sensing ion channels(ASICs) are highly expressed in some brainstem chemosensory breathing regulatory areas, but their localization and functions in the LC remain unknown. Mild hypercapnia increases the amount of non-REM(NREM) sleep and the number of REM sleep episodes, but whether ASICs in the LC modulate S–W is unclear. Here, we investigated the presence of ASICs in the LC and their role in S–W modulation and the state transition from NREM to REM sleep. Male Wistar rats were surgically prepared for chronic polysomnographic recordings and drug microinjections into the LC. The presence of ASIC-2 and ASIC-3 in the LC was immunohistochemically *** of amiloride(an ASIC blocker) and APETx2(a blocker of ASIC-2 and-3) into the LC significantly decreased wakefulness and REM sleep, but significantly increased NREM sleep. Mild hypercapnia increased the amount of NREM and the number of REM episodes. However, APETx2 microinjection inhibited this increase in REM frequency. These results suggest that the ASICs of LC neurons modulate S–W, indicating that ASICs could play an important role in vigilance-state transition. A mild increase in CO_2 level during NREM sleep sensed by ASICs could be one of the determinants of state transition from NREM to REM sleep.

关键词： Acid-sensing ion channels Carbon dioxide Hypercapnia NREM sleep REM sleep

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Unsteady natural convection Couette flow of heat generating/absorbing fluid between vertical parallel plates filled with porous material

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Applied Mathematics and Mechanics(English Edition) 2012年第3期33卷 303-314页

作者： B.k.jha M.k.MUSA Department of Mathematics Ahmadu Bello UniversityZaria 234Nigeria Mathematics Unit School of Basic and Remedial StudiesAhmadu Bello UniversityFuntua 6007Nigeria

The extended Brinkman Darcy model for momentum equations and an energy equation is used to calculate the unsteady natural convection Couette flow of a viscous incompressible heat generating/absorbing fluid in a vertical channel （formed by two infinite vertical and parallel plates） filled with the fluid-saturated porous medium. The flow is triggered by the asymmetric heating and the accelerated motion of one of the bounding plates. The governing equations are simplified by the reasonable dimensionless parameters and solved analytically by the Laplace transform techniques to obtain the closed form solutions of the velocity and temperature profiles. Then, the skin friction and the rate of heat transfer are consequently derived. It is noticed that, at different sections within the vertical channel, the fluid flow and the temperature profiles increase with time, which are both higher near the moving plate. In particular, increasing the gap between the plates increases the velocity and the temperature of the fluid, however, reduces the skin friction and the rate of heat transfer.

关键词： heat generating/absorbing fluid natural convection flow porous material acceleration motion

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A comprehensive analysis of the role of molecular docking in the development of anticancer agents against the cell cycle CDk enzyme

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BIOCELL 2023年第4期47卷 707-729页

作者： PRIYANkA SOLANkI NISARG RANA PRAkASH C.jha ANU MANHAS Department of Chemistry Pandit Deendayal Energy UniversityGandhinagar382426India School of Applied Material Sciences Central University of GujaratGandhinagar382030India

Cancer is considered one of the most lethal diseases responsible for causing deaths *** there have been many breakthroughs in anticancer development,cancer remains the major cause of death *** this regard,targeting cancer-causing enzymes is one of the efficient therapeutic *** functions like cell cycle,transcription,metabolism,apoptosis,and other depend primarily on cyclin-dependent kinases(CDks).These enzymes help in the replication of DNA in the normal cell cycle process,and deregulation in the functioning of any CDk can cause abnormal cell growth,which leads to *** review is focused on anticancer drug discovery against cell cycle CDk enzyme using an in silico technique,i.e.,molecular docking *** docking helps in deciphering the key interactions formed within the inhibitor and the respective *** concise study provides an overview of the most current in silico research advancements made in the field of anticancer drug *** findings presented in the current review article can help in understanding the nature of inhibitor-target interactions and provide information on the structural and molecular prerequisites for the inhibition of cell cycle CDks.

关键词： CDks Cancer Molecular docking

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A Component Selection Framework of Cohesion and Coupling Metrics

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Computer Systems Science & Engineering 2023年第1期44卷 351-365页

作者： M.Iyyappan Arvind kumar Sultan Ahmad Sudan jha Bader Alouffi Abdullah Alharbi Department of Computer Science and Engineering SRM UniversityDelhi-NCRSonepat131029India Department of Computer Science College of Computer Engineering and SciencesPrince Sattam Bin Abdulaziz UniversityAlkharj11942Saudi Arabia School of Sciences Christ(Deemed to be University)Delhi-NCRGhaziabad201003India Department of Computer Science College of Computers and Information TechnologyTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Department of Information Technology College of Computers and Information TechnologyTaif UniversityP.O.Box 11099Taif21944Saudi Arabia

Component-based software engineering is concerned with the develop-ment of software that can satisfy the customer prerequisites through reuse or inde-pendent *** and cohesion measurements are primarily used to analyse the better software design quality,increase the reliability and reduced system software *** complexity measurement of cohesion and coupling component to analyze the relationship between the component *** this paper,proposed the component selection framework of Hexa-oval optimization algorithm for selecting the suitable components from the *** measures the interface density modules of coupling and cohesion in a modular software *** cohesion measurement has been taken into two parameters for analyz-ing the result of complexity,with the help of low cohesion and high *** coupling measures between the component of inside parameters and outside *** process of coupling and cohesion,the measured values were used for the average calculation of components *** paper measures the complexity of direct and indirect interaction among the component as well as the proposed algorithm selecting the optimal component for the *** better result is observed for high cohesion and low coupling in compo-nent-based software engineering.

关键词： Component-based software system coupling metric cohesion metric complexity component interface module density

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A Real-time Cutting Model Based on Finite Element and Order Reduction

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Computer Systems Science & Engineering 2022年第10期43卷 1-15页

作者： Xiaorui Zhang Wenzheng Zhang Wei Sun Hailun Wu Aiguo Song Sunil kumar jha Wuxi Research Institute Nanjing University of Information Science&TechnologyWuxi214100China Engineering Research Center of Digital Forensics Ministry of EducationJiangsu Engineering Center of Network MonitoringSchool of Computer and SoftwareNanjing University of Information Science&TechnologyNanjing210044China School of Automation Nanjing University of Information Science&TechnologyNanjing210044China State key Laboratory of Bioelectronics Jiangsu Key Lab of Remote Measurement and ControlSchool of Instrument Science and EngineeringSoutheast UniversityNanjing210096China IT Fundamentals and Education Technologies Applications University of Information Technology and Management in RzeszowRzeszow Voivodeship100031Poland

Telemedicine plays an important role in Corona Virus Disease 2019(COVID-19).The virtual surgery simulation system,as a key component in telemedicine,requires to compute in ***,this paper proposes a realtime cutting model based on finite element and order reduction method,which improves the computational speed and ensure the real-time *** proposed model uses the finite element model to construct a deformation model of the virtual ***,a model order reduction method combining proper orthogonal decomposition and Galerkin projection is employed to reduce the amount of deformation *** addition,the cutting path is formed according to the collision intersection position of the surgical instrument and the lesion area of the virtual ***,the Bezier curve is adopted to draw the incision outline after the virtual lung has been ***,the simulation system is set up on the PHANTOM OMNI force haptic feedback device to realize the cutting simulation of the virtual *** results show that the proposed model can enhance the real-time performance of telemedicine,reduce the complexity of the cutting simulation and make the incision smoother and more natural.

关键词： Virtual surgery cutting model finite element model model order reduction Bezier curve

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Effects of the COVID-19 pandemic on semen quality in male partners of infertile couples: a hospitalbased observational study

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Asian Journal of Andrology 2023年第2期25卷 240-244页

作者： Tribhuwan kumar kamlesh jha Md Zabihullah kumari Neelu Yogesh kumar kumar Siddharth Department of Physiology All India Institute of Medical SciencesPatna 801507BiharIndia Akshat Spandan Clinic Patna 801507BiharIndia

The effects of the coronavirus disease 2019(COVID-19)pandemic on male fertility have received considerable attention because human testes contain high levels of angiotensin-converting enzyme-2 receptors,through which severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can *** studies showed decreases in semen quality during and after recovery from ***,no semen quality studies have examined the effects of widespread subclinical and mild disease,as well as changes in lifestyle,psychosocial behavior,intake of dietary supplements,and *** cross-sectional study compared semen quality parameters in male partners of infertile couples between men who underwent semen analysis before the COVID-19 pandemic(prepandemic group)and men who underwent semen analysis during the pandemic period(pandemic group);the analysis sought to clarify the overall effects of the *** participants in the pandemic group had experienced clinically overt *** the 239 participants,mean body weight(P=0.001),mean body mass index(P<0.001),median sperm concentration(P=0.014),total sperm count(P=0.006),and total percentages of motile(P=0.013)and abnormal cells(P<0.001)were significantly greater in the pandemic group(n=137)than those in the prepandemic group(n=102).Among abnormal cells,the percentages of cells with excess residual cytoplasm(P<0.001),head defects(P<0.001),and tail defects(P=0.015)were significantly greater in the pandemic group than those in the prepandemic *** the exception of morphology,the overall semenogram results were better in the pandemic group than those in the prepandemic group.

关键词： coronavirus disease 2019 pandemic male infertility SARS-CoV-2 semen analysis

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