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Duality for a Control Problem involving Support Functions

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Applied Mathematics 2014年第21期5卷 3525-3535页

作者： i. Husain Abdul Raoof Shah Rishi K. Pandey Department of Mathematics Jaypee University of Engineering and Technology Guna India Department of Statistics University of Kashmir Srinagar India

Mond-Weir type duality for control problem with support functions is investigated under generalized convexity conditions. Special cases are derived. A relationship between our results and those of nonlinear programmin... 详细信息

关键词： Control Problem Support Function Generalize Convexity Converse Duality Nonlinear Programming

Speech Encoding Scheme for the Extra-Cochlear Pulsed Electrical Stimulation System

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Open Journal of Acoustics 2018年第3期8卷 52-60页

作者： Yuta Tamai Kazuyuki Matsumoto Shizuko Hiryu Kohta i. Kobayasi Life and Medical Science Doshisha University Kyoto Japan

An extra-cochlear stimulation system has been investigated as a less invasive alternative to conventional cochlear implant;however, the system is used primarily as a speech-reading aid. The purpose of this study was to develop a speech encoding scheme for the extra-cochlear stimulation system to convey intelligible speech. A click-modulated speech sound (CMS) was created as a simulation of the extra-cochlear stimulation system. The CMS is a repetitive click with a repetition rate similar to the formant frequency transition of an original sound. Seven native Japanese speakers with normal hearing participated in the experiment. After listening to the CMS, synthesized from low familiarity Japanese words, the subjects reported their perceptions. The results showed that the rates of correctly identified vowels and consonants were significantly higher than those of the control stimulus, suggesting that the CMS can generate at least partially intelligible vowel and consonant perceptions. in all, the speech encoding scheme could be applied to the extra-cochlear stimulation system to restore speech perception.

关键词： Auditory Prosthesis Cochlear implant Noninvasive Stimulation System Speech Perception

Survival of <i>Staphylococcus aureus</i>in Bio-Yoghurt

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Open Journal of Applied Sciences 2019年第7期9卷 564-572页

作者： Neveen S. M. Soliman Lamiaa i. Ahmed Department of Food Hygiene & Control Faculty of Veterinary Medicine Cairo University Giza Egypt

introduction: Due to the increasing demand for natural probiotic products, yogurt is the most popular type of fermented dairy products. Aim: Yoghurt produced using probiotic bacteria and its effect on Staphylococcus aureus as a pathogenic microorganism is discussed as compared with traditional yoghurt. Material and method: The influence of yoghurt using starter culture on S. aureus during manufacture and storage for three brands of Lab. made yoghurt (A, B and C) was judged as excellent concerning the total acceptability. Result: The inoculated S. aureus decreases in number by the end of the storage period. in addition, the best effect of inhibition was observed in brand (B) using yoghurt starter with Lactobacillus acidophilus, followed by brand (C) using yoghurt starter L. acidophilus together with Bifidobacterium bifidum and the least effect was belonging to brand (A) using yoghurt starter only. This inhibitory effect may be attributed either to the probiotic bacteria itself or to the antibacterial substances secreted by them. Conclusion: The authors recommended the consumption of bio-yoghurt as it is not only palatable but also, safe due to improved hygienic quality.

关键词： Yoghurt Probiotics Lactobacillus acidophilus Bifidobacterium bifidum

<i>in silico</i>analysis of influence of the missense mutation P629S on the molecular interaction and 3D properties of PiK3R5

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Advances in Biological Chemistry 2013年第4期3卷 408-417页

作者： Jameela Shinwari Asma i. Tahir Saeed Bohlega Nada AlTassan Department of Genetics King Faisal Specialist Hospital and Research Centre Riyadh KSA Department of Neurosciences King Faisal Specialist Hospital and Research Centre Riyadh KSA

PiK3R5 is the regulatory subunit of Phosphoinositide 3-kinase γ (Pi3Kγ) that is responsible for phosphory-lating membrane lipids to activate the AKT pathway. PiK3R5 binds Gβγ and facilitates the interaction with p110γ catalytic subunit (PiK3CG) during Pi3Kγ activation. The identification of PiK3R5 P629S mutation in AOA2 patients indicated a potential defect in the AKT pathway resulting from impaired PiK3R5 interaction with Gβγ and PiK3CG, defective AKT pathway can result in cerebellar cell death causing neurological symptoms. Our in silico macromolecular docking of the wild type and mutant PiK3R5 protein models with ligand revealed an energy requirement to maintain the mutant complexes compared to no energy required to maintain the wild type complexes, in addition, the mutant structures were loose compared to rigid wild type structures, such structural changes may impair the molecular function of the PiK3R5 and hence affect the AKT pathway.

关键词： PiK3R5 Missense Mutation Protein Modelling Protein-Protein Docking PiK3CG Gβγ

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作者： i·阿西莫夫(i Asimov)

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地震工程和土动力问题译文集

地震工程和土动力问题译文集

Changes in Ammonium and pH within intertidal Sediments in Relation to Temperature and the Occurrence of Non-indigenous Bivalves

作者： i.M.·伊德里斯(i.M. idriss)

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Open Journal of Marine Science 2014年第3期4卷 151-162页

作者： Leah i. Bendell Kayi Chan Sophie Crevecoeur Charlotta Prigent Department of Biological Sciences Simon Fraser University Burnaby Canada

Our objective was to determine the role of two invasive bivalves on the concentration of ammonium as well as pH within intertidal surface sediments (0 - 3 and 3 - 6 cm depth) and interstitial waters, within the context of a warming environment. To meet this objective we applied both controlled laboratory (microcosm) and field (mesocosm) experiments where we varied bivalve presence and absence and sediment temperature. Mesocosm sampling was tide dependent as we attempted to capture changes in ammonium concentration and pH as related to flood and ebb tide. We focused on ammonium as this nutrient is typically a limiting nutrient in oceanic systems and its cycling is a key process that regulates biological productivity. We also determined pH because of the increasing threat of ocean acidification. integration of laboratory and field studies suggests that bivalves significantly contribute to ammonium to the intertidal with this amount increasing with increasing temperature. This ammonium is then released from the sediment as a “pulse” to overlying seawater on the flood tide. Under laboratory conditions, increased temperature and density of bivalves decreased overlying water pH. Mesocosm studies suggested some tide dependence of pH with flood tide acting as a buffer, increasing pH on the flood tide, after sediment exposure during ebb tide. increased numbers of invasive bivalves within a warming environment are likely to increase amounts of ammonium released as a pulse on flood tides from intertidal ecosystems making this region a source of ammonium to coastal seas. Greater numbers of non-indigenous bivalves within the intertidal could also contribute to increased acidity within these regions although the significance of such increases is unknown.

关键词： Non-indigenous Bivalves Temperature intertidal Ammonium Flood Tide